• 한국자동차공학회논문집
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• 제14권6호
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• pp.112-119
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• 2006

This paper is concerned with the light-weight design of a center-pillar assembly for the high-speed side impact of vehicle using advanced high strength steels(AHSS). Steel industries continuously promote the ULSAB-AVC project for applying AHSS to structural parts as an alternative way to improve the crashworthiness and the fuel efficiency because it has the superior strength compared to the conventional steel. In order to simulate deformation behavior of the center-pillar assembly, a simplified center-pillar model is developed and parts of that are subdivided employing tailor-welded blanks(TWB) in order to control the deformation shape of the center-pillar assembly. The thickness of each part which constitutes the simplified model is selected as a design parameter. Factorial design is carried out aiming at the application and configuration of AHSS to simplified side-impact analysis because it needs tremendous computing time to consider all combinations of parts. In optimization of the center-pillar, S-shaped deformation is targeted to guarantee the reduction of the injury level of a driver dummy in the crash test. The objective function is constructed so as to minimize the weight and lead to S-shape deformation mode. Optimization also includes the weight reduction comparing with the case using conventional steels. The result shows that the AHSS can be utilized effectively for minimization of the vehicle weight and induction of S-shaped deformation.

• 대한전자공학회논문지SP
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• 제39권6호
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• pp.641-651
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• 2002

전송 오류율이 높은 이동통신 환경에서 동영상 서비스를 제공하려면 전송오류에 대한 검출 및 은닉이 필요하다. 본 논문에서는 MPEG-4 동영상 비트열을 구성하는 비디오 패킷 데이터가 손실되었을 때, 수신단에서 간단히 손상된 영상을 복구해낼 수 있는 적응적 오류은닉 방법을 제안한다. 제안된 방법은, 손실된 비디오 패킷에 포함되었을 매크로블록의 개수가 영상의 움직임 특성을 반영한다는 사실을 이용하여, 블록 반복 및 움직임 보상을 적응적으로 사용하므로써 영상 오류를 은닉하게 된다. 실험 결과, 제안 방법은 영상에 존재하는 움직임 특성에 따라 효과적으로 사용됨을 알 수 있었다. 일반적으로 손쉽게 사용될 수 있는 블록 반복 은닉 방법 혹은 움직임 보상 은닉 방법과 비교하여 최대 1dB 이상의 화질 개선이 있었으며, 주관적 화질 측면에서도 우수한 결과를 얻었다.

• 전기학회논문지
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• 제56권6호
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• pp.1170-1176
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• 2007

The conventional urodynamic monitoring is fulfilled by artificially filling a bladder with saline. Generally. it is difficult to evaluate the physiological functions of the storage and voiding of a bladder. With this aim, we constructed an ambulatory urodynamic monitoring (AUM) system and proposed a novel method estimating abdominal pressure by measuring bio-impedance variations. Our system was clinically evaluated for 10 patients. It turned out to be that as the intensity of the abdomen contraction increased, the amplitude of bio-impedance signal and the RMS value of EMG increased more as compared to those who observed during the rest mode. Also, we determined the optimum electrode pair for estimating the abdominal pressure using bio-impedance method and consequently compared with the conventional methods. Because impedance changes differ from a weight, a height, contractile force, volume of muscle and blood other or whatever of individuals, it was quantified in terms of impedance change, correlation coefficient and SNR Our results showed the optimum electrode pair (1,9) which could detect impedance changes due to the increase of the intensity in the abdominal pressure. The correlation coefficient and quadratic function between the RMS values of EMG and the impedance changes were 0.87 and $y=0.0014x^2+0.0620x+0.6958$, respectively. Thus, our system demonstrated that the abdominal pressure could be measured noninvasively and conveniently by simply estimating bio-impedance values. We propose that this optimum electrode configuration would be useful for the future studies involving the handy measurements of abdominal pressure with our suggested ambulatory urodynamics monitoring system.

• 대한전자공학회논문지SD
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• 제38권11호
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• pp.828-835
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• 2001

고정도 전류-모드 신호 처리를 위한 새로운 바이폴라 트랜스레지스턴스 증폭기(TRA)와 이것의 오프셋 보상된 TRA를 제안하였다. 두 TRA는 전류 입력을 위한 두 개의 전류 폴로워, 전류차를 얻기 위한 전류 가산기, 전류를 전압으로 변환시키기 위한 저항, 그리고 전압 출력을 위한 전압 폴로워로 구성되었다. 오프셋 보상된 TRA는 TRA의 오프셋 전압을 감소시키기 위한 다이오드 결선된 npn과 pnp 트랜지스터를 채용하였다. 시뮬레이션 결과, TRA근 입-출력 단자에서 0.5 Ω의 임피던스와 40 mV의 오프셋 전압을 갖고 있다는 것이 확인되었다. 오프셋 보상된 TRA는 1.1 mV의 오프셋 전압과 0.25 Ω의 임피던스를 갖고 있다. 두 개의 TRA를 단위-이득의 트랜스레지스턴스를 갖는 전류-전압 변환기로 이용할 때 3-dB 차단 주파수는 40 MHz이다. 제안한 두 TRA의 전력 소비는 11.25 mW이다.

• 한국광학회지
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• 제17권4호
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• pp.371-380
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• 2006

금으로 된 금속선 광 도파로를 따라 속박되는 장거리 표면 플라즈몬을 이용하여 파장 가변 필터를 설계하고 제작하였다. 실리콘 기판 위에 제작된 금속선 도파로는 두 층의 열광학 폴리머 사이에 샌드위치 구조로 끼어 있도록 설계되었다. 도파로의 바로 윗면에는 유전체로 된 Bragg 회절격자가 적합한 주기로 제작되어, 중심 파장이 광통신 파장대 (1520$\sim$1570 nm)에 있으면서 높은 소광률($\sim$25 dB)을 갖는 파의 반사가 가능했고, 전체손실은 25 dB/cm 이하로 나타났다. 또한, 제작된 파장 가변 필터가 폴리머의 열-광학적 특성에 의해 파장가변 필터 소자로서의 응용이 가능함을 확인했으며, 금속선 광 도파로에 직접 연결된 전극 구조에 동시에 가해준 전류에 의해 파장이 가변 될 수 있음을 실험적으로 확인하였다.

• Imaging Science in Dentistry
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• 제49권4호
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• pp.301-306
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• 2019

Purpose: This report presents a procedure for performing power Doppler ultrasound-guided sialography using the phenomenon of increased blood flow and illustrates its application to practical patient cases. Materials and Methods: The salivary gland was scanned using ultrasound equipment (GE LOGIQ5 Expert^® device; GE Medical Systems, Milwaukee, WI, USA) to identify pathological findings related to the patient's chief complaint. To identify the orifice of the main duct, it should be cannulated using a lacrimal dilator. After inserting the catheter into the cannulated main duct, the position of the catheter within the duct was confirmed by ultrasound. A contrast agent was injected until the patient felt fullness, and ultrasound (B-mode) was used to confirm whether the contrast agent filled the main canal and secondary and tertiary ducts. Then, power Doppler ultrasound was performed to determine whether the salivary gland had increased blood flow. Results: In 2 cases in this report, a power Doppler ultrasound scan showed a significant increase in blood flow after contrast medium injection, which was not observed on a preoperative scan. Conclusion: Power Doppler ultrasound was found to be a simple, safe, and effective tool for real-time sialography monitoring.

• 한국식품위생안전성학회지
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• 제5권3호
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• pp.159-164
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• 1990

To detect and quantitation residual antibiotics and antibacterial agents in meats, we performed a biological assay employing the three microorganisms Bacillus subtilis ATCC 6633, Micrococcus luteus ATCC 9341, and Bacillus cereus var. mycoides ATCC 11778 for the screening purpose and developed a Gas Chromatography-mass Spectrometry(GC/MS) analysis for the confirmation and quantiation. In the biological assay (paper disk method), three test solution are used depending on the character of the residual antibiotics and antibacterial agents, follow by a simple clean up procedure which includes homogenization with Mcilvaine buffer, defatting with includes homogenization with Mcilvaine buffer, defatting with hexane, extraction with chloroform, clean-up by Sep-Pak $C_{18}$ and Bakerbond SPE carboxylic acid column. The chloroform layer is used for the analysis of sulfa agents. macrolides antibiotics and antibacterial agents, Adsorbed materials in the Sep-Pak $C_{18}$ were also employed for th analysis of penicillins and tetracyclines. Effluents from the Sep-Pak $C_{18}$ were cleaned-up one more by Bakerbond 10 SPE COOH column and employed for the analysis of aminoglycosides. In the instrumental analysis by using the GC/MSD, residual antibiotics and antibacterial agent were quantitated by selected ion monitoring (SIM) mode after derivatization. A simultaneous analysis of six residual antibiotic and antibacterial agent such as oxytetracycline, penicillin, ampicillin, choliraphenicol and thiamphenicol was developed with simple cleanup procedures revealing good recovery and reproducibility. Also, simultaneous detection of macrolides antibiotics such as erythromycin, spiramycin, and oleandomycin was developed after acid hydrolysis due to their large molecular structures. Because of the high reproducibility and selectivity of these two methods, it is very desirable that the combination of the two methods be used in the bioassay for the screening of residual antibiotics and antibacterial agent and that GC/MSD analysis be used for the confirmation and quantitation.

• 대한약침학회지
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• 제16권1호
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• pp.43-49
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• 2013

Objective: Pyungwi-san (PWS) plays a role in a number of physiologic and pharmacologic functions in many organs. Interstitial cells of Cajal (ICCs) are pacemaker cells that generate slow waves in the gastrointestinal (GI) tract. We aimed to investigate the beneficial effects of PWS in mouse small-intestinal ICCs. Methods: Enzymatic digestion was used to dissociate ICCs from the small intestine of a mouse. The whole-cell patch-clamp configuration was used to record membrane potentials from the cultured ICCs. Results: ICCs generated pacemaker potentials in the GI tract. PWS produced membrane depolarization in the current clamp mode. Pretreatment with a $Ca^{2+}$-free solution and a thapsigargin, a $Ca^{2+}$-ATPase, inhibitor in the endoplasmic reticulum, eliminated the generation of pacemaker potentials. However, only when the thapsigargin was applied in a bath solution, the membrane depolarization was not produced by PWS. Furthermore, the membrane depolarizations due to PWS were inhibited not by U-73122, an active phospholipase C inhibitor, but by chelerythrine and calphostin C, protein kinase C inhibitors. Conclusions: These results suggest that PWS might affect GI motility by modulating the pacemaker activity in the ICCs.

• 동의생리병리학회지
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• 제27권5호
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• pp.520-529
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• 2013

Needham Problem(NP) is the influential question that English historian of Chinese science Joseph Needham raised, "Why modern science had not developed in the Chinese civilisation but only in that of Europe?" Our objectives in this paper are as follows: First, we will revisit NP in the broad context of the emergence of modernity rather than treating it just as an internal problem of Chinese science. After that, the problem of modernity in Chinese medicine will be discussed from the viewpoint of NP. After NP's intellectual backgrounds are summarized, its value and implications are examined, and then Needham's own answers are presented. Afterwards, we present supplementary hypotheses, adapted from Weber, as our solution to NP in Chinese science and medicine. Needham thought that the European scientific revolution would not have been possible without the rise of modern capitalism. He also believed that Chinese bureaucratism facilitated early development of Chinese science and in turn, inhibited later radical change by interrupting the rise of capitalism. According to our hypotheses, scientific changes are related to social changes, especially to the legitimation crises, which lead to the alternations of mode of justification in sciences. The Chinese society did not go through the legitimation crises as the European society did, and therefore it failed to produce a radically different kind of justification from the traditional one. This is the reason why there was no revolution in science and medicine in China.

• 한국위성정보통신학회논문지
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• 제6권1호
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• pp.28-31
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• 2011

본 논문에서는 d33 모드로 구동하여 우수한 성능을 가지는 RF-MEMS 스위치의 구현을 위한 희생층과 구조층의 조합으로서 DLC와 포토레지스트를 제안하였다. 포토레지스트의 경화현상을 방지하기 위하여 DLC 구조층은 상온에서 RF-PECVD 방법을 이용하여 증착하였다. 그리고 PZT 압전층은 RF 마그네트론 스퍼터링 방법을 이용하여 상온에서 구조층 위에 증착하였으며, 희생층의 제거 후 결정화를 위하여 급속 열처리 (RTA) 장비를 이용하여 후 열처리하였다. PZT의 결정화 과정과 DLC의 기계적 성질의 변화를 다양한 온도조건에 따라 분석한 결과 DLC는 PZT의 결정화 온도까지 영률과 강도면에서 우수한 특성을 나타냄을 확인하였다. 또한 포토레지스트를 사용함으로서 공정을 단순화하고 낮은 비용으로 제작이 가능하였다.