• 약학회지
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• 제47권5호
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• pp.325-330
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• 2003

Solanum melongena L. (Solanaceae) has anti-oxidant, analgesic, and hypolipidemic effects. We previously showed that Solanum melongena (SM) aqueous extract inhibits mast cell-mediated allergic reactions. The activation of protease-activated receptor-2 (PAR-2) induces acute inflammation in rat hindpaw. In the present study, we investigated the effects of the SM aqueous extract on mouse paw edema induced by PAR2 agonists. Trypsin or trans-cinnamoyl-LIGRLO-NH$_2$ (tc-NH$_2$), PAR-2 agonists, was injected into the hind paw of mice to induce paw edema. SM aqueous extract (1, 5, 10, and 100 mg/kg) was orally administered 1 hr before induction of paw edema. SM aqueous extract (5, 10, and 100 mg/kg) significantly inhibited both paw edema and vascular permeability in the dose-dependent manner. Furthermore, SM aqueous extract (10 mg/kg) significantly inhibited PAR-2 agonist-induced myeloperoxidase (MPO) activity and tumor necrosis factor (TNF)-$\alpha$ expression in paw tissue compared to that of saline. These results suggest that SM aqueous extract may be useful for treatment of PAR-2-mediated inflammation.

• 생약학회지
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• 제41권2호
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• pp.89-93
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• 2010

Korean folk medicine 'GaJi' has been used to treat a boil, cough, mushroom poisoning and stomach cancer. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'GaJi', the morphological and anatomical characteristics of the stems of Solanum species growing in Korea, i.e. S. japonense Nakai, S. lyratum Thunb., S. melongena L., S. nigrum L. were compared. As a result, it was determined that GaJi was the stem of Solanum melongena L.

• Archives of Pharmacal Research
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• 제28권6호
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• pp.657-659
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• 2005

A new biflavonol glycoside named as solanoflavone (1) was isolated from aerial part of Solanum melongena. The chemical structure was elucidated as isorhamnetin-3-O-$\beta$-D-glucopyranoside-(4'$\to$O$\to$4"')-galangin-3"-O-$\to$-D-glucopyranoside on the basis of physicochemical and spectroscopic methods, including 2D NMR spectral techniques.

• Journal of Applied Biological Chemistry
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• 제59권2호
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• pp.103-106
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• 2016

가지 잎으로부터 3종의 phenylpropanoid, 1종의 flavonoid glycoside, 그리고 1종의 norsesquiterpenoid glycoside 화합물을 분리 동정하였다. 가지 잎을 80 % MeOH로 추출하였으며, 얻어진 추출물을 n-hexane, EtOAc, n-BuOH 및 물 층으로 계통분획을 실시하였다. 이 중 n-BuOH 분획에 대하여 $SiO_2$, ODS 및 Sephadex LH-20 column chromatography를 반복 실시하여 5종의 화합물을 분리, 정제하였다. Nuclear magnetic resonance, infrared spectroscopy 및 mass spectrometry의 spectroscopic data를 해석하여 이 화합물들을 caffeic acid (1), chlorogenic acid (2), cryptochlorogenic acid (3), panasenoside (4), 및 (6R,7E,9R)-4,7-megastigmadien-3-one-9-${\beta}$-${\small{D}}$-glucopyranoside (5) 로 각각 동정하였다. 본 연구에서 화합물 3과 4는 가지 잎에서 처음으로 분리, 동정하였다.

• Mycobiology
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• 제33권3호
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• pp.163-165
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• 2005

In April 2002 and 2003, soft rot on fruit of eggplant (Solanum melongena) caused by Choanephora cucurbitarum was observed in the experimental fields at Gyeongnam Agricultural Research and Extension Services in Korea. The disease began with water-soaking and dark-green lesions, and then the infected tissues were rapidly rotten. Sporangium was subglobose in shape and sized $40{\sim}130\;{\mu}m$. Monosporous sporangiola were elliptic, fusiform or ovoid, brown in color, and measured as $12{\sim}20\;{\times}\;6{\sim}14\;{\mu}m$. Sporangiospores having three or more appendages were elliptic, fusiform or ovoid in shape, dark brown or brown in color, and sized $14{\sim}20\;{\times}7{\sim}16\;{\mu}m$. The fungus grew well on potato dextrose agar between 15 and $40^{\circ}C$ and its optimum growth temperature was $30^{\circ}C$. Based on morphological characteristics, the causal fungus of the fruit soft rot of eggplant was identified as C. cucurbitarum. This is the first report on the soft rot of S. melongena caused by C. cucurbitarum in Korea.

• 한국식품영양과학회지
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• 제30권1호
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• pp.133-137
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• 2001

21종 식용식물의 부위별 MeOH Ex. DPPH와 TBA법으로 항산화 효과를 조사한 결과 DPPH를 이용한 유리라디칼 소거 효과는 참취잎, 쑥갓잎 및 머위잎에서 특이적으로 높은 효과가 관찰되었으며 시료추출물의 buffer에 의해 유발된 과산화지질 억제효과는 참외껍질의 억제 효과 강도는 $IC_{50}$ 값이 $10\mu\textrm{g}/mL$로 매우 강하였다. $S_2O_z$로 유발시킨 지질과산화에 대한 억제효과는 0.25 mg 농도에서 L-ascorbic acid의 과산화 억제율과 비교하면 가지 잎, 머위 잎, 감자껍질의 항산화 억제 효과가 가장 높았으며 $FeSO_4$로 유발시킨 지질과산화에 대한 억제효과는 쑥갓잎의 $IC_{50}$가 0.08 mg/mL로 특이적으로 높았다.

• Current Research on Agriculture and Life Sciences
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• 제5권
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• pp.19-26
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• 1987

Solanum melongena var. fructualbo 품종(品種)을 이용(利用)해서 원형질체 유리(遊離)에 미치는 여러 가지 요인(要因)을 규명하여 원형질체를 배양(培養)하여 금후(今後) 유용(有用)한 체세포잡종식물의 획득(獲得)에 필요한 기초자료로 활용하고자 실험(實驗)하였다. CPW 무기염이 함유(含有)된 0.7M mannitol 용액(溶液)에 1시간(時間)동안 전처리(前處理)한 후(後) cellulase 1.5%, macerozyme 0.2%, mannitol 0.6M, MES 0.01M, BSA 0.2%, pH 6.3에서 4시간(時間) 배양(培養)한 것이 원형질체 수량(收量) 및 상태(狀態)가 가장 양호(良好)하였다. 수세용액내(水洗溶液內) mannitol 농도(濃度)는 0.7M에서, sucrose 농도(濃度)는 0.6M로 하여 ESSCC방법(方法)으로 회수(回收)하는 것이 건전하고 안정(安定)된 원형질체 대량획득(大量獲得)에 적합하였으며, 거의 최적조건을 이용(利用)하여 처리(處理)된 원형질체를 $2.5{\times}10^4/m{\ell}$의 밀도(密度)로 8P-KM배지(培地)에 배양(培養)했을 때 3~5일(日)부터 세포신장(細胞伸長)을 하였고, 그 이후(以後)부터 세포분열(細胞分裂)이 이루어져 10일(日) 후(後)부터 colony 형성(形成)이 관찰되었다.

• BMB Reports
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• 제30권2호
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• pp.150-156
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• 1997

Tyrosinase was purified from Solanum melongena by ammonium sulfate precipitation, Sephadex G-150 and DEAE-Sephacel column chromatography. The molecular weight of the purified tyrosinase was approximately 88,600 daltons with 805 amino acid residues. The amino acid composition showed the characteristic high contents of glycine, glutamic acid and serine residues. The enzyme had high substrate specificity towards (+)-catechin. The $K_m$, value for L-DOPA was 20.8 mM. L-ascorbic acid, ${\beta}-mercapto-ethanol$, sodium diethyldithiocabamate, KCN and $NaN_3$ had strong inhibitory effects on enzyme activity. Sodium diethyldithiocabamate was a competitive inhibitor of the enzyme with a $K_i$ value of $5.2{\times}10^{-2}\;mM$. The optimum pH of the enzyme was 9.0 and the optimum temperature was $65^{\circ}C$ with L-DOPA as a substrate. In addition, the activity was enhanced by addition of $Ca^{+2}$ or $Cu^{+2}$, but decreased in the presence of $Fe^{2+},Fe^{3+}$ and $Zn^{2+}$ ions.

• 농업과학연구
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• 제38권4호
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• pp.625-629
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• 2011

To investigate the protective effect of eggplant (Solanum melongena L.) and its active compound, delphinidin, we used in vitro and cellular system. The active fraction from eggplant, BuOH fraction, showed protective effect from hydrogen peroxide-induced oxidative stress in WI-38 fibroblast cells. It suggests that eggplant would have the protective activity from radical-induced oxidative damage and its BuOH fraction would play the crucial role with antioxidative activity. In addition, delphinidin, the active compound from eggplant, exerted the strong 1,1-diphenyl-2-picrylhydrazyl scavenging effect with $IC_{50}$ value of 6.59 ${\mu}g/mL$. Furthermore, the cellular oxidative stress was induced by 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH) in LLC-$PK_1$ cells, while treatment of delphinidin atteunated AAPH-induced oxidative stress as dose-dependent manner. The present study suggests the antioxidative activity of eggplant and delphinidin against free radical-induced oxidative stress.

• 한국환경과학회지
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• 제33권6호
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• pp.417-425
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• 2024

This study investigated the effects of various planting models on the joint cultivation of eggplant (Solanum melongena) and marigold (Tagetes erecta)to enhance sustainable rooftop urban farming. Rooftop agriculture is increasingly valued to boost the food supply and benefit the environment. Integrating such practices into urban planning is viewed as a way to sustainably manage resources and improve the food-energy-water cycle in cities. The experiment was conducted on a rooftop in Chungju, South Korea from May to August. Four different planting setups were used: central eggplant with peripheral marigold (SET), eggplant with a protective net (SIC), central marigold with peripheral eggplant (TES), and control with only eggplant (CON S). These models tested the effects of companion planting versus monoculture using a lightweight soil mix ideal for rooftops made from cocopeat and perlite and enriched with organic fertilizer. Measurements focused on soil conditions and plant health and assessed soil temperature, moisture, conductivity, plant height, width, and leaf size. The results indicated that the SET modelyielded the best growth. This setup benefited from marigold pest control properties and its ability to improve soil conditions by enhancing moisture and nutrient levels and aiding eggplant growth. These findings underscore the potential of mixed planting on rooftops and suggest that such approaches can be effectively incorporated into urban agriculture to boost yield and environmental sustainability. This study supports the idea that diverse planting methods can significantly affect plant growth and promote urban greening and food security.