• Journal of computational fluids engineering
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• v.12 no.2
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• pp.21-25
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• 2007

A general purpose program NUFLEX has been extended for two-phase flows with topologically complex interface and cavitation flows with liquid-vapor phase change caused by large pressure drop. In analysis of two-phase flow, the phase interfaces are tracked by employing a LS(Level Set) method. Compared with the VOF(Volume-of-Fluid) method based on a non-smooth volume-fraction function, the LS method can calculate an interfacial curvature more accurately by using a smooth distance function. Also, it is quite straightforward to implement for 3-D irregular meshes compared with the VOF method requiring much more complicated geometric calculations. Also, the cavitation process is computed by including the effects of evaporation and condensation for bubble formation and collapse as well as turbulence in flows. The volume-faction and continuity equations are adapted for cavitation models with phase change. The LS and cavitation formulation are implemented into a general purpose program for 3-D flows and verified through several test problems.

• Bulletin of the Korean Mathematical Society
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• v.60 no.4
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• pp.1085-1100
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• 2023

For any given function f, we focus on the so-called prescribed mean curvature problem for the measure e^-f(|x|2)dx provided thate^-f(|x|2) ∈ L¹(ℝⁿ⁺¹). More precisely, we prove that there exists a smooth hypersurface M whose metric is ds² = dρ² + ρ²d𝜉² and whose mean curvature function is ${\frac{1}{n}}(\frac{u^p}{{\rho}^{\beta}})e^{f({\rho}^2)}{\psi}(\xi)$ for any given real constants p, β and functions f and ψ where u and ρ are the support function and radial function of M, respectively. Equivalently, we get the existence of a smooth solution to the following quasilinear equation on the unit sphere 𝕊ⁿ, $${\sum_{i,j}}({{\delta}_{ij}-{\frac{{\rho}_i{\rho}_j}{{\rho}^2+|{\nabla}{\rho}|^2}})(-{\rho}ji+{\frac{2}{{\rho}}}{\rho}j{\rho}i+{\rho}{\delta}_{ji})={\psi}{\frac{{\rho}^{2p+2-n-{\beta}}e^{f({\rho}^2)}}{({\rho}^2+|{\nabla}{\rho}|^2)^{\frac{p}{2}}}}$$ under some conditions. Our proof is based on the powerful method of continuity. In particular, if we take $f(t)={\frac{t}{2}}$, this may be prescribed mean curvature problem in Gauss measure space and it can be seen as an embedded result in Gauss measure space which will be needed in our forthcoming papers on the differential geometric analysis in Gauss measure space, such as Gauss-Bonnet-Chern theorem and its application on positive mass theorem and the Steiner-Weyl type formula, the Plateau problem and so on.

• Clinical and Experimental Pediatrics
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• v.48 no.6
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• pp.580-587
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• 2005

New evidence is emerging that airway smooth muscle(ASM) may act as an immunomodulatory cell by providing pro-inflammatory cytokines and chemokines, polypeptide growth factors, extracellular matrix proteins, cell adhesion receptors and co-stimulatory molecules. ASM can promote the formation of the interstitial extracellular matrix, and potentially contribute to the alterations within the extracellular matrix in asthma. In addition, extracellular matrix components can alter the proliferative, survival, and cytoskeletal synthetic function of ASM cells through integrin-directed signaling. Increased ASM mass is one of the most important features of the airway wall remodeling process in asthma. Three different mechanisms may contribute to the increased ASM mass : cell proliferation, increased migration and decreased rate of apoptosis. The major signaling pathways of cell proliferation activated by ASM mitogens are those dependent on extracellular signal-regulated kinase and phosphoinositide 3'-kinase. The key signaling mechanisms of cell migration have been identified as the p38 mitogen-activated protein kinase and the p21-activated kinase 1 pathways. ASM cells contain ${\beta}2$-adrenergic receptors and glucocorticoid receptors. They may represent a key target for ${\beta}2$-adrenergic receptor agonist/corticosteroid interactions which have antiproliferative activity against a broad spectrum of mitogens.

• Structural Engineering and Mechanics
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• v.42 no.1
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• pp.121-129
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• 2012

All contemporary seismic Codes have adopted smooth design acceleration response spectra, which have derived by statistical analysis of many elastic response spectra of natural accelerograms. The above smooth design spectra are characterized by two main branches, an horizontal branch that is 2.5 times higher than the peak ground acceleration, and a declining parabolic branch. According to Eurocode EN/1998, the period range of the horizontal, flat branch is extended from 0.1 s, for rock soils, up to 0.8 s for softer ones. However, from many natural recorded accelerograms of important earthquakes, the real spectral amplification factor appears to be much higher than 2.5 and this means that the spectrum leads to an unsafe seismic design of the structures. This point is an issue open to question and it is the object of the present study. In the present paper, the spectral amplification factor of the smooth design acceleration spectra is re-calculated on the grounds of a known "reliability index" for a desired probability of exceedance. As a pilot scheme, the seismic area of Greece is chosen, as it is the most seismically hazardous area in Europe. The accelerograms of the 82 most important earthquakes, which have occurred in Greece during the last 38 years, are used. The soil categories are taken into account according to EN/1998. The results that have been concluded from these data are compared with the results obtained from other strong earthquakes reported in the World literature.

• Mycobiology
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• v.48 no.2
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• pp.153-156
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• 2020

Calvatia nipponica, a puffball mushroom (Agaricaceae), is thought to be an aphrodisiac, as this mushroom is traditionally known to improve sexual function in males. As part of the systematic study to determine the bioactive secondary metabolites from C. nipponica responsible for aphrodisiac effects, chemical analysis of methanol (MeOH) extracts of the fruiting bodies of C. nipponica resulted in the isolation of two major compounds: N,N-dimethyl-anthranilic acid (1) and (7Z,10Z)-7,10-octadecadienoic acid methyl ester (2). Compounds 1 and 2 were evaluated for cumulative dose-dependent relaxation responses to precontracted penile corpus smooth muscle (PCCSM). Results show that compounds 1 and 2 exhibited a maximum relaxation effect of 20.33 ± 2.18% and 24.63 ± 3.60%, respectively. These findings indicate that compounds 1 and 2, major components of C. nipponica, could potentially be used to treat erectile dysfunction, functioning as natural aphrodisiacs.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.3 s.168
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• pp.107-114
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• 2005

A new approach which combines implicit surface scheme and point projection method is presented in order to fill the arbitrarily shaped holes in the polygon model. In the method a trimmed surface which has an outer boundary curve is generated by using the implicit surface scheme and normal projection of point onto the base surface. The base surface is constructed by creating smooth implicit surface from the incomplete polygon model through which the surface should pass. In this paper an implicit surface is defined by a radial basis function, a continuous scalar-valued function over the domain $R^3$. The base surface is the set of all points at which this scalar function takes on the value zero and is created by placing zero-valued constraints at the vertices of the polygon model. In order to show the validity of the present study, various hole fillings are carried out for the complex polygon model of arbitrary topology.

• International Journal of Precision Engineering and Manufacturing
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• v.8 no.1
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• pp.3-10
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• 2007

A new approach based on implicit surface interpolation combined with domain decomposition is proposed for filling complex-shaped holes in a large polygon model, A surface was constructed by creating a smooth implicit surface from an incomplete polygon model through which the actual surface would pass. The implicit surface was defined by a radial basis function, which is a continuous scalar-value function over the domain $R^{3}$. The generated surface consisted of the set of all points at which this scalar function is zero. It was created by placing zero-valued constraints at the vertices of the polygon model. The well-known domain decomposition method was used to treat the large polygon model. The global domain of interest was divided into smaller domains in which the problem could be solved locally. The LU decomposition method was used to solve the set of small local problems; the local solutions were then combined using weighting coefficients to obtain a global solution. The validity of this new approach was demonstrated by using it to fill various holes in large and complex polygon models with arbitrary topologies.

• Transactions of the Korean Society of Mechanical Engineers
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• v.19 no.9
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• pp.2237-2248
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• 1995

In incompressible flow which has multi-length scale, it has a very important effect which dependent variables are used for adaptive grid generation. Among many length scales in incompressible flow, the dependent variables used for the adaptive grid generation should be able to represent the feature of the concerned system. In this paper, by using vorticity and stream function, in addition to velocity components, the smoother and more stable grid generation is possible and these four flow properties represent each scale. The adaptive grid generation for a lid-driven cavity flow with $N_{re}$ =3200 using four flow properties such as velocity components, vorticity, stream function is performed, and the usefulness of using vorticity and stream function as the indicator for adaptive grid generation is shown.

• Journal of international Conference on Electrical Machines and Systems
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• v.3 no.1
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• pp.1-6
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• 2014

A new sensorless control strategy for brushless DC (BLDC) motors is proposed in this paper. This technique builds a rotor position-related flux function, which is independent of the speed. By observing the flux function, the information of rotor position and commutation can be obtained. As the function is not speed-related, this control process can be used in a wider range of speed and improves the motor's performance during startup. An experimental test bad based on TMS320F2812 has been built, and the experimental result indicates that the motor achieves a smooth starting-up and stable phase commutation with the proposed control strategy.

• The Korean Journal of Applied Statistics
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• v.14 no.2
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• pp.333-344
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• 2001

통계적 추론에 사용되는 많은 통계량들은 평균벡터의 평활함수의 형태로 표현이 가능하다. 본 연구에서는 이들 통계량들의 분포함수에 대한 안부점근사법을 제시하였다. 이 방법은 Na(1998)에서 제시된 일반적 통계량의 분포함수에 대한 안부점근사법이 평균벡터의 평활함수모형에 특히 유용하게 사용될 수 있음을 보인 것이다. 이 근사법은 정규근사에 비해 근사의 정도가 뛰어나며, 특히 통계량의 꼬리부분의 확률에 대해서도 정확도가 그대로 유지되는 장점이 있어 정밀한 추론이 요구되는 많은 문제에 효과적으로 사용될 수 있다. 모의 실험에 사용할 평균벡터의 평활함수 모형으로는 스튜던트화 분산을 고려하였다.