• 제목/요약/키워드: Slow design

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Preparation and Characterization of Cisplatin-Incorporated Chitosan Hydrogels, Microparticles, and Nanoparticles

  • Cha, Ju-Eun;Lee, Won-Bum;Park, Chong-Rae;Cho, Yong-Woo;Ahn, Cheol-Hee;Kwon, Ick-Chan
    • Macromolecular Research
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    • v.14 no.5
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    • pp.573-578
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    • 2006
  • Three different, polymer-platinum conjugates (hydrogels, microparticles, and nanoparticles) were synthesized by complexation of cis-dichlorodiammineplatinum(II) (cisplatin) with partially succinylated glycol chitbsan (PSGC). Succinic anhydride was used as a linker to introduce cisplatin to glycol chitosan (GC). Succinylation of GC was investigated systematically as a function of the molar ratio of succinic anhydride to glucosamine, the methanol content in the reaction media, and the reaction temperature. By controlling the reaction conditions, water-soluble, partially water-soluble, and hydrogel-forming PSGCs were synthesized, and then conjugated with cisplatin. The complexation of cisplatin with water-soluble PSGC via a ligand exchange reaction of platinum from chloride to the carboxylates induced the formation of nano-sized aggregates in aqueous media. The hydrodynamic diameters of PSGC/cisplatin complex nano-aggregates, as determined by light scattering, were 180-300 nm and the critical aggregation concentrations (CACs), as determined by a fluorescence technique using pyrene as a probe, were $20-30{\mu}g/mL$. The conjugation of cisplatin with partially water-soluble PSGC, i.e., borderline between water-soluble and water-insoluble PSGC, produced micro-sized particles $<500{\mu}m$. Cisplatin-complexed PSGC hydrogels were prepared from water-insoluble PSGCs. All of the cisplatin-incorporated, polymer matrices released platinum in a sustained manner without any significant initial burst, suggesting that they may all be useful as slow release systems for cisplatin. The release rate of platinum increased with the morphology changes from hydrogel through microparticle to nanoparticle systems.

Design of Evolvable Hardware based on Genetic Algorithm Processor(GAP)

  • Sim Kwee-Bo;Harashiam Fumio
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.5 no.3
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    • pp.206-215
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    • 2005
  • In this paper, we propose a new design method of Genetic Algorithm Processor(GAP) and Evolvable Hardware(EHW). All sorts of creature evolve its structure or shape in order to adapt itself to environments. Evolutionary Computation based on the process of natural selection not only searches the quasi-optimal solution through the evolution process, but also changes the structure to get best results. On the other hand, Genetic Algorithm(GA) is good fur finding solutions of complex optimization problems. However, it has a major drawback, which is its slow execution speed when is implemented in software of a conventional computer. Parallel processing has been one approach to overcome the speed problem of GA. In a point of view of GA, long bit string length caused the system of GA to spend much time that clear up the problem. Evolvable Hardware refers to the automation of electronic circuit design through artificial evolution, and is currently increased with the interested topic in a research domain and an engineering methodology. The studies of EHW generally use the XC6200 of Xilinx. The structure of XC6200 can configure with gate unit. Each unit has connected up, down, right and left cell. But the products can't use because had sterilized. So this paper uses Vertex-E (XCV2000E). The cell of FPGA is made up of Configuration Logic Block (CLB) and can't reconfigure with gate unit. This paper uses Vertex-E is composed of the component as cell of XC6200 cell in VertexE

Design of Crank Drive System Based on Gait Pattern for Stand-up Bicycle (보행패턴을 접목한 직립주행 자전거용 크랭크 구동장치의 거동분석)

  • Hyeong, Joonho;Roh, Jongryun;Kim, Sayup
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.10
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    • pp.991-996
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    • 2017
  • Gait stability is partly characterized by an extended stance phase that comprises 60 of the gait % cycle. In this study, a gait pattern was employed for a crank drive system that allows for stable lower limb kinematics during stand-up cycling. A quick return mechanism was applied to the crank system to allow for a slow rotation of the crank during the stance phase and for a quick return during the swing phase. Design parameters for the quick return crank mechanism were defined, and kinematic simulations were performed to understand the behavior of the mechanism. To evaluate the design, an experimental instrument was fabricated, and the cycling motion was analyzed. The results indicated that this new drive system can stabilize the center of mass of the user. This study can contribute to the development of a stand-up bicycle that allows for more comfortable leg kinematics.

Design of the Fuel Cell Powered Line-Interactive UPS System (연료전지 시스템을 이용한 Line-Interactive 방식의 무정전 전원 공급 장치의 설계)

  • Choi, Woo-Jin;Jeon, Hee-Jong
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.18 no.6
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    • pp.205-212
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    • 2004
  • In this paper the design of a 1-[KVA] fuel cell powered line-interactive UPS system employing modular (fuel cell & DC/DC converter) blocks is proposed. The proposed system employs the two fuel cell modules along with suitable DC/DC converters and these modules share the DC-Link of the DC/AC inverter. A supercapacitor module is also employed to compensate for the instantaneous power fluctuations and to overcome the slow dynamics of the fuel processor. The energy stored in the supercapacitor can also be utilized to handle the overload conditions for a short time period. Due to the absence of batteries, the system satisfies the demand for an environmentally friendly and dean source of the energy. A complete design example illustrating the amount of hydrogen storage required for 1hr power outage, and sizing of supercacpacitor for transient load demand is presented for a 1-[KVA] UPS.

Design of the Robust Generalized Sinusoidal Frequency Modulated Pulse in Reverberation Environments (잔향환경에 강인한 Generalized Sinusoidal Frequency Modulated 펄스 생성 기법)

  • Kim, Guenhwan;Yoon, Kyungsik;Lee, Donghwa;Cho, Chomgun;Hong, Jungpyo;Lee, Kyunkyung
    • Journal of Korea Society of Industrial Information Systems
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    • v.24 no.5
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    • pp.95-104
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    • 2019
  • In this paper, we propose a method to design a generalized sinusoidal frequency modulated(GSFM) pulse that is robust to reverberation environment. GSFM pulses are a generalized form of SFM(Sinusoidal frequency modulated) pulses, which have the advantage of having a thumbtack ambiguity function with excellent range and Doppler resolution. However, the periodicity disappears during the generalization process, therefore, the detection performance is reduced in reverberation environment compared to SFM pulse with comb spectrum. In this paper, the trade-off relationship between the reverberation suppression performance of the SFM pulse and the range resolution performance of the GSFM pulse is analyzed by appropriately changing the parameter ${\rho}$ of the GSFM pulse. In order to verify the performance of the proposed GSFM pulse, the simulation was performed and it was confirmed that the proposed GSFM pulse has excellent distance resolution while detecting the slow Doppler target.

A Research on Characteristics of Internal Flow Based on the Gun Barrel Length and Ammunition Pressure. (포신 길이와 탄약 압력에 따른 포신 내부 유동 특성 연구)

  • Jung, Hee-Chur;Kim, Kyoung-Rok;Kang, Yo-Han;Ban, Young-Woo;Jung, Duck-Hyeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.513-520
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    • 2018
  • This research concerns the characteristics of tank barrel inner flow according to the barrel length and the pressure of ammunition when fired. By analyzing the flow characteristics of the bore evacuator according to barrel length and ammunition pressure regarding ammunition design, it is possible to prevent the flareback phenomenon that may occur during ammunition operation. Through bore evacuator flow analysis by barrel length and ammunition pressure, we identified key design factors concerning barrel and ammunition compatibility including speed, accuracy, penetration performance and range. Test results found if barrel length is long and ammunition pressure is low, bore evacuator operation time is slow. Therefore, there is a high probability that propellant gas will enter the battle vehicle. Therefore, the correlation analysis method of bore evacuator flow characteristics based on barrel length and ammunition pressure is considered as a primary method to improve operational performance. When designing new ammunition, the correlation analysis method will be used to determine ammunition weight and select the propellant pressure.

An Optimal Design Method of a Linear Generator for Conversion of Wave Energy (파력에너지 변환을 위한 선형발전기의 최적 설계 방법)

  • Kim, Jung-Yoon;Kim, Byung Soo
    • The Journal of the Korea institute of electronic communication sciences
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    • v.16 no.6
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    • pp.1195-1204
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    • 2021
  • In this paper, we present an optimal design method for wave power generators using the response surface analysis. Especially, in our method, we reduce the mechanical loss by selecting the linear generator whose linear movement can be converted to the electrical energy directly with the vertical movement of waves. Therefore, we calculate the exciting force acting on the drive device in a slow-wave condition and determine the winding process with a ratio of the slots and poles for the improvement of energy conversion efficiency. In addition, we employ the regression analysis for deriving the shape factors of the stator and the translator, which have a significant effect on the performance of a generator. We choose the best design variables through the response surface analysis, and then we study the optimization method for designing the efficient experiment using the analysis results. Finally, we show the validity of the proposed method through the simulation results.

Analysis of 3D Building Construction Applications in Augmented Reality

  • Khan, Humera Mehfooz;Waseemullah, Waseemullah;Bhutto, Muhammad Aslam;Khan, Shariq Mahmood;Baig, Mirza Adnan
    • International Journal of Computer Science & Network Security
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    • v.22 no.10
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    • pp.340-346
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    • 2022
  • Construction industry is considered as one of the oldest industries in the world since human came into being and the need of their own space is realized. All this led to make the world a space of many beautiful constructive ventures. As per the requirements of today's world, every industry is recognizing the need for use and adoption of modern as well as innovative technologies due to their benefits and timely production. Now construction industry has also started adopting the use of modern and innovative technologies during their projects but still the rate of adoption is so slow. From design to completion, construction projects take a lot to manage for which technology based solutions have continuously been proposed. These include Computer Aided Design (CAD), building information modeling (BIM) and cloud computing have been proved to be much successful until now. The construction projects are high budgeted, and direly require timely and successful completion with quality, resource and other constraints. So, the researchers observe the need of more clear and technology based communication between the construction projects and its constructors and other stakeholders is required before and during the construction to take timely precautions for expected issues. This study has analyzed the use of Augmented Reality (AR) technology adopting GammaAR, and ARki applications in construction industry. It has been found that both applications are light-weighted, upgradable, provide offline availability and collaborative environment as well as fulfil most of the requirements of the construction industry except the cost. These applications also support different screen size for better visualization and deep understanding. Both applications are analyzed, based on construction's application requirements, usability of AR and ratings of applications user collected from application's platform. The purpose of this research is to provide a detail insight of construction applications which are using AR to facilitate both the future developers and consumers.

Effects of 'Methylen Urea' Slow Released Fertilizer and 'T-Vigor' Microbial Fertilizer as Environmental Fertilizer on Growth of Creeping Bentgrass in Golf Course (친환경적 비료인 완효성 비료 'Methylen Urea' 및 미생물 비료 'T-Vigor' 처리가 골프장 그린의 크리핑 벤트크래스 생육에 미치는 영향)

  • Lee Kyeung-Ju;Lee Jae-Pil;Kim Doo-Hwan
    • Asian Journal of Turfgrass Science
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    • v.18 no.2
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    • pp.63-70
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    • 2004
  • This study was conducted to figure out the effect of 'Methlyen Urea(MU)', slow released fertilizer and 'T-Vigor', microbial fertilizer as environment fertilizer on growth of 'Crenshaw' creeping bentgrass for environmental management in golf course. This study was conducted at No. 3, 4, 5 Valley Courses of Rexfield Country Club from April to July in 2004. MU, T-Vigor, sterilized T-Vigor were applied five times with 5g and 7.5ml per square meter, respectively. Polt size was 1 square meter and there were three replications with Completely Randomize Design. Collecting data were turf density$(No.\;of\;shoot\;/cm^2)$, chlorophyll $amount(\%)$, root length(cm), dry weight of clipping(g), and dry weight of root(g). The results are as follows; All of turf density, chlorophyll amount and dry weight(g) of MU and T-Vigor were better than control and sterilized T-Vigor. Especially root length of MU and T-Vigor was superior to control and sterilized T-Vigor, even if temperature and humidity was high. In conclusion, MU and T-Vigor might be used as slow release fertilizer for environmental green management in golf course.

Minimizing Design of the Schiffman Phase Shifter Using the Defected Ground Structure (결함접지면을 이용한 쉬프만 위상 천이기의 소형화)

  • Kim, Gi-Rae
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.13 no.9
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    • pp.1745-1752
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    • 2009
  • This Paper represents a new method, which uses defected ground structure (DGS) on the ground planes of microstrip lines, to reduce the size of the Schiffman phase shifter. DGS on the microstrip line shows an increased slow-wave effect due to the additional equivalent L and C components. So the electrical length of transmission line with DGS is longer than that of standard transmission line for the same physical length. Then, the length of transmission line with DGS can be shortened in order to maintain the original electrical length to be same. The performances of reduced phase shifter with DGS are quite similar to the ones of original Schiffman phase shifters. We can reduce the size about 15% using the DGS in original Schiffman phase shifter.