• Title/Summary/Keyword: Skin knowledge

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Stress Hormone Cortisol Damages the Skin Barrier by Regulating Tight Junctions (밀착연접 조절을 통한 스트레스 호르몬 코티졸의 피부장벽 손상 연구)

  • Lee, Sung Hoon;Son, Eui Dong;Choi, Eun-Jeong;Park, Won-Seok;Kim, Hyoung-June
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.46 no.1
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    • pp.73-80
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    • 2020
  • Psychological stress can affect the physiological condition of the skin and cause various cutaneous disorders. The stress hormone cortisol is secreted by various skin cells such as fibroblasts, keratinocytes, and melanocytes. Tight junctions (TJs) are cell-cell junctions that form a barrier in the stratum granulosum of mammalian skin. TJs can also affect other skin barriers and are affected by chemical, microbial, or immunological barriers. Stress can cause damage to the skin barrier. Interestingly, to our knowledge, there has not been any research demonstrating the involvement of TJs in this process. In this study, cortisol was used to treat keratinocytes to determine its role in regulating TJs. We found that cortisol damaged skin barrier function by regulating the gene expression and structure of TJ components. Cortisol also inhibited the development of the granular layer in a skin equivalent model. These results suggest that cortisol affects the skin barrier function by the regulation of TJs.

Assessing a Sun Protection Program Aimed at Greek Elementary School Students for Malign Melanoma Prevention

  • Saridi, Maria Ioannis;Rekleiti, Maria Demetrios;Toska, Aikaterini George;Souliotis, Kyriakos
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.12
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    • pp.5009-5018
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    • 2014
  • Introduction: Numerous countries have launched campaigns regarding sun protection in the last decades. Aim: The aim of the present study was to assess an intervention program aimed at higher knowledge and healthier attitudes regarding sun protection. Materials and Methods: The sample consisted of 4,133 students aged 8-12 years from a single Greek province. Results: In most items, knowledge levels after the intervention were found to be higher than those before ($2.8{\pm}0.9$ vs $3.3{\pm}0.9$), while knowledge about sun protection factors seems to have had the highest improvement (27.1% vs 56.6%). However, student attitudes did not appear to improve, with the exception of applying sunscreen with a higher SPF (29.7% vs 54.8%). Girls seemed to have healthier attitudes compared to boys, but gender played no role with regard to knowledge levels. Also, place of residence did not play any role regarding knowledge levels, although those living in semi-urban areas seemed to have more unhealthy attitudes. Logistic regression by correlating knowledge and attitudes established that higher knowledge levels are usually accompanied by healthier attitudes, albeit marginally. Conclusions: The intervention had a positive contribution to the student knowledge level regarding sun protection and also led to small improvements regarding some attitudes. Continuous similar interventions could lead to better results and the adoption of healthier attitudes.

Knowledge of Diaper Dermatitis and Diaper Hygiene Practices among Mothers of Diaper-wearing Children (영유아 어머니의 기저귀 발진에 대한 지식 및 기저귀 관리 실태)

  • Kim, Jin Sun;Jeong, Yong Sun;Jeong, Eun Jin
    • Child Health Nursing Research
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    • v.25 no.2
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    • pp.112-122
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    • 2019
  • Purpose: The purpose of this study was to investigate the prevalence of diaper dermatitis (DD), knowledge of DD prevention and treatment, and diaper hygiene practices among mothers with diaper-wearing children. Methods: The participants were 176 mothers who presented to an outpatient clinic at a children's hospital with diaper-wearing children. Data were collected using a structured self-administered questionnaire. Results: The percent of correct answer for knowledge about DD was 59.7%. Almost half of the participants' children had experienced at least 1 episode of DD during the last 6 months. Inappropriate diaper hygiene practices, such as using talcum powder on DD and rubbing with a dry towel after cleansing, were reported. Moreover, only 37% of mothers used the recommended skin barrier to prevent DD. Although many children suffer from DD, levels of educational experience and perceived need for education on this topic were low. Almost 70% of mothers obtained DD-related information through internet sites. Conclusion: Educating parents about the etiology of DD and evidence-based diaper hygiene practices is an important aspect of effective DD prevention and treatment. Internet sites or smartphone apps may be effective methods for education on DD prevention and treatment considering parents' preferences for ways to obtain health information.

Successful Management of Hepatic Lipidosis Accompanied by a Feline Skin Fragility Syndrome-like Lesion in a Cat (고양이 피부유약증 유사병변을 동반한 지방간에 이환된 한 마리 고양이의 성공적인 치료증례)

  • Park, Hyoung-Jin;Hong, Eun-Ji;Kwon, Hyo-Jung;Park, Seong-Jun;Park, Joo Min;Song, Kun-Ho;Seo, Kyoung-Won
    • Journal of Veterinary Clinics
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    • v.32 no.5
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    • pp.449-453
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    • 2015
  • A 7-year-old spayed female Somali-cross cat was admitted with a 4-week history of anorexia, vomiting, weight loss, and lethargy. The cat was diagnosed with hepatic lipidosis. With intensive care and nutritional support via a nasogastric feeding tube for 3 weeks, the clinical signs of hepatic lipidosis were improved. However, skin lesions were found in the left and right scapular regions during the treatment that were suspected to be due to feline skin fragility syndrome (FSFS). Intensive wound healing therapy with granulated sugar, laser therapy, and a surgical flap was conducted. Skin lesions improved uneventfully without other clinical signs or recurrence of any skin lesion for a year. To our knowledge, this is the first report of a good prognosis in a hepatic disorder and concurrent FSFS.

Serological and molecular prevalence of lumpy skin disease virus in Korean water deer, native and dairy cattle in Korea

  • Ko, Young-Seung;Oh, Yeonsu;Lee, Taek Geun;Bae, Da-Yun;Tark, Dongseob;Cho, Ho-Seong
    • Korean Journal of Veterinary Service
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    • v.45 no.2
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    • pp.133-137
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    • 2022
  • Lumpy skin disease (LSD) is a severe cross-border infectious disease that causes fever, skin and visceral nodules in cattle. LSD is caused by the lumpy skin disease virus (LSDV), a dsDNA virus that belongs to the genus Capripoxvirus. Although LSD has been found only in Southern Africa traditionally, in the last decade it is spreading very quickly through the Middle East and into Eastern Europe and China. It usually affects cattle and water buffalos being transmitted by blood-feeding insects. As it causes a huge economic impact, LSD is a notifiable disease by World Organisation for Animal Health, and managed as the legal infectious disease class I in Korea. Therefore, the purpose of this study was to confirm the existence of LSDV antigens or antibodies in Korean livestock. We collected 1,200 blood samples from cattle (Korean native and dairy cattle) and Korean water deer in 4 major provinces of the country, then tested the existence of LSDV antigen and antibody. None (0.0%) of the 1,200 blood samples were positive for both antigen and antibody of LSDV. To the best of our knowledge, this is the first study that examines the prevalence of LSDV in Korea. Our study aims to report the LSDV occurrence situation obtained by surveillance in Korea and provide information that may help prevention of LSD epidemics.

Metastasizing Dermatofibroma to Lungs: A Case Report (폐로 전이한 피부섬유종: 증례보고)

  • Choi, Se Woon;Suh, Man Soo;Park, Sae Jung;Lim, Yeung Kook
    • Archives of Plastic Surgery
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    • v.33 no.5
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    • pp.663-665
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    • 2006
  • Purpose: Dermatofibroma is a lesion several millimeters to several centimeters in size, arising from dermis or subcutaneous tissue, mostly at extremities of a middle aged female. It is a benign fibrous tumor that to our knowledge metastasis have not been reported and may recur only locally. Here we report a rare case of 36-year-old female with dermatofibroma arising from back and metastasized to both lungs. Methods: We performed an en-block elliptical mass excision for skin lesion and metastatectomy for multiple nodules of both lungs. Results: Histologically, the tumors of both lungs and skin lesion showed dilated cystic airspaces which were lined by respiratory epithelium with underlying layers of tumor cells. The tumor cells were composed of plump to spindled fibrohistiocytic cells arranged in storiform growth pattern. There were no cellular pleomorphism, atypical mitosis, and necrosis. These are the specific features of a dermatofibroma and we could examined the histologic findings of skin and lungs identical. Thus, this indicates that dermatofibroma of back was metastasized to both lungs. Conclusion: We report this case to notice that dermatofibroma is a benign tumor but it rarely metastasizes.

Cutaneous melanocytic tumor in a slaughtered pig (도축돈에서 발생한 피부 멜라닌 세포성 종양)

  • Yang, Hyoung-Seok;Kang, Sang-Chul;Bae, Jong-Hee;Kim, Jae-Hoon
    • Korean Journal of Veterinary Research
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    • v.46 no.3
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    • pp.275-278
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    • 2006
  • A 7-month-old brown pig with a discoid and pedunculate mass measuring $14.0{\times}12.5{\times}2.5cm$ on the skin of the right shoulder was noted at the slaughter house in Jeju. The surface of mass approximately $7{\times}4cm$ was interfaced with skin. The color of mass with firm consistency was mainly black and partially white on cut surface. Histopathologically, numerous unencapsulated endocrine-like cellular nodules of epithelioid cell type with abundant intracytoplasmic black pigment, melanin, were occupied in dermis and subcutis. Most of nodules in deep dermis were surrounded by lightly pigmented spindle cells and loose fibrous tissues. Mitotic figures were infrequently observed. The overlying epidermis was hyperplastic due to the down-growth of rete peg. Based on the gross and histopathologic findings, this case was diagnosed as cutaneous melanoma. In our best knowledge, this is the first case of swine cutaneous melanoma in Korea.

Face region detection algorithm of natural-image (자연 영상에서 얼굴영역 검출 알고리즘)

  • Lee, Joo-shin
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.7 no.1
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    • pp.55-60
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    • 2014
  • In this paper, we proposed a method for face region extraction by skin-color hue, saturation and facial feature extraction in natural images. The proposed algorithm is composed of lighting correction and face detection process. In the lighting correction step, performing correction function for a lighting change. The face detection process extracts the area of skin color by calculating Euclidian distances to the input images using as characteristic vectors color and chroma in 20 skin color sample images. Eye detection using C element in the CMY color model and mouth detection using Q element in the YIQ color model for extracted candidate areas. Face area detected based on human face knowledge for extracted candidate areas. When an experiment was conducted with 10 natural images of face as input images, the method showed a face detection rate of 100%.

A study on the Preference of Material quality and the Demand Performance of Clothing for Underwear Materials (내의 소재에 대한 재질선호 및 요구 성능에 대한 연구)

  • Park, Young-Hee
    • Fashion & Textile Research Journal
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    • v.11 no.1
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    • pp.147-155
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    • 2009
  • This study has been made to examine the basic information, the preferences of material quality, and the demand performance of clothing for underwear materials between atopic patients and non-patients. The measurement tool was a questionnaire. For statistical analysis of data, crosstabs, ${\chi}^2$-test, t-test and ANOVA through SPSS for Windows(version 14.0) were used. The results obtained are as follows. The degree of the basic knowledge about clothing materials indicated that women was higher than men. The material decision method and the most considering part in case of selecting underwear products showed difference between men and women. The preference factors for underwear material quality were drawn with the five factors of sense of weight/pliability, lustering/see-through, tactility, and sense of cold and warmth. The preferred underwear material showed difference according to gender, existence and nonexistence of atopic determatitis, and degree of strength of skin itching caused by clothing materials. The demand performances of clothing in case of selecting underwear were drawn with the four factors of hygiene/practicality, skin protection, quality of materials, and aesthetic attribute. The demand performance of underwear showed difference according to gender, existence and nonexistence of atopic determatitis, degree of strength of skin itching caused by clothing materials.

Delayed Allergic Reaction to Secondary Administrated Epidural Hyaluronidase

  • Park, A Reum;Kim, Woong Mo;Heo, Bong Ha
    • The Korean Journal of Pain
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    • v.28 no.2
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    • pp.153-155
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    • 2015
  • We are reporting a rare case of a delayed hypersensitivity reaction caused by hyaluronidase allergy following a lumbar transforaminal epidural block. Using an intradermal skin test, we have provided evidence that the systemic allergic reaction resulted from hypersensitivity to hyaluronidase. To our knowledge, this is a rare case of a delayed hypersensitivity reaction to epidural hyaluronidase, comprised of an initial exposure to hyaluronidase with no subsequent allergic response in prior block followed by a subsequent delayed reaction to hyaluronidase during a second epidural block.