• Title/Summary/Keyword: Skeletal

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Diversity of contractile properties in skeletal muscle fibers (골격근 섬유의 수축성 특성의 다양성)

  • Kim, Sik-hyun
    • PNF and Movement
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    • v.2 no.1
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    • pp.35-47
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    • 2004
  • Purpose : The purpose of this article was to review the literature on contractile properties of skeletal muscle with reference to its molecular and functional diversity. Method : This review outlines scientific findings regarding different contractile properties in skeletal muscle fibers, and discusses their involvement in functional diversity. Result & Conclusions: Muscle fibers possess distinct mechanical and energetic properties. Myosis, one of the primary contractile muscle proteins, displays structural, functional variability and plays the role of the molecular motor of muscle contraction. Muscle satellite cells are normally mitotically quiescent, but initiate proliferation and give rise to daughter myogenic precursor cells as required for the postnatal growth and regeneration of adult muscle. Passive extensibility is an important component of total muscle function because it allows for the maximal length of skeletal muscles. Proprioceptive neuromuscular facilitation(PNF) stretching can help to restore or improve flexibility and coordination, thereby improving overall muscle function.

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Productivity Enhancement of Automotive Glass Manufacturing Company by the Improvement of Working Environment (작업환경 개선을 통한 자동차 유리제조업체의 생산성 향상)

  • Yang Sung Hwan;Cho Mun Son;Park Peom
    • Journal of the Korea Safety Management & Science
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    • v.7 no.2
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    • pp.85-94
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    • 2005
  • The purpose of this study is to execute the investigation of injurious factors causing muscle-skeletal diseases at an automotive glass manufacturing company and, on the basis of the results, to enhance productivity by the improvement of working environment. By using an survey and an ergonomic evaluation method, symptoms of muscle-skeletal diseases of workers and working postures at each process were analyzed, and quantitative evaluation of muscle-skeletal disease risk against each process was performed. Based on the result of the evaluation, to enhance the working environment, improvement of worktable, working space, tools, and outfit was suggested, and induction of mechanical system was also suggested. Suggested improvement plan was applied to the workplace step by step and it is confirmed that improvement plan not only removes the injurious factors of muscle-skeletal diseases but also is effective to enhance productivity.

Postmortem skeletal muscle metabolism of farm animals approached with metabolomics

  • Susumu Muroya
    • Animal Bioscience
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    • v.36 no.2_spc
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    • pp.374-384
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    • 2023
  • Skeletal muscle metabolism regulates homeostatic balance in animals. The metabolic impact persists even after farm animal skeletal muscle is converted to edible meat through postmortem rigor mortis and aging. Muscle metabolites resulting from animal growth and postmortem storage have a significant impact on meat quality, including flavor and color. Metabolomics studies of postmortem muscle aging have identified metabolisms that contain signatures inherent to muscle properties and the altered metabolites by physiological adaptation, with glycolysis as the pivotal metabolism in postmortem aging. Metabolomics has also played a role in mining relevant postmortem metabolisms and pathways, such as the citrate cycle and mitochondrial metabolism. This leads to a deeper understanding of the mechanisms underlying the generation of key compounds that are associated with meat quality. Genetic background, feeding strategy, and muscle type primarily determine skeletal muscle properties in live animals and affect post-mortem muscle metabolism. With comprehensive metabolite detection, metabolomics is also beneficial for exploring biomarker candidates that could be useful to monitor meat production and predict the quality traits. The present review focuses on advances in farm animal muscle metabolomics, especially postmortem muscle metabolism associated with genetic factors and muscle type.

Age-Related Loss of Skeletal Muscle and Associated Risk Factors in Middle-Aged Men: A Comprehensive Study

  • Jongseok Hwang
    • Journal of the Korean Society of Physical Medicine
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    • v.18 no.2
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    • pp.13-21
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    • 2023
  • PURPOSE: This study examined the specific clinical risk factors in middle-aged men with age-related loss of skeletal muscle mass (ALSMM). METHODS: The present research analyzed the data from a cross-sectional study of 1,564 community-dwelling participants aged between 40 to 49 years old. The participants were screened for ALSMM. The study examined various risk factors, including age, height, weight, body mass index, waist circumference, skeletal muscle mass index, smoking and drinking status, systolic and diastolic blood pressure, fasting glucose levels, and triglyceride and cholesterol levels. RESULTS: The risk factors of ALSMM were height, body mass index, waist circumference, skeletal muscle mass index, systolic blood pressure, diastolic blood pressure, drinking status, fasting glucose, and triglyceride levels (p < .05). The weight, triglyceride, and smoking status variables were non-significant (p > .05). CONCLUSION: The risk factors for ALSMM among community-dwelling adults were determined. These results are expected to contribute to the existing literature on ALSMM and provide potential risk factors associated with the development of ALSMM in middle-aged males.

Effects of activator treatment on different skeletal patterns in growing class II malocclusion patients (성장기 II급 부정교합자에서 골격 형태에 따른 액티베이터 사용 효과에 관한 연구)

  • Ki, Jun-Hun;Lee, Jin-Woo
    • The korean journal of orthodontics
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    • v.37 no.1 s.120
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    • pp.29-43
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    • 2007
  • Objective: To establish proper diagnosis and treatment plan for skeletal Class II malocclusions, some important factors to consider are the patient's skeletal morphology, prognosis as well as the treatment effects. Therefore, the present study analyzed the effects of activator treatment on different skeletal patterns in growing Class II malocclusion patients. Methods: A total of 116 patients (53 boys & 63 girls) in the experimental group were treated with the activator appliance. The experimental group was classified into either hyperdivergent or hypodivergent groups according to articular and genial angles. Results: Patients with hypodivergent growth patterns showed good effects of activator treatment. Conclusion: It seems conceivable that through classifying adolescent Class II malocclusion patients into different skeletal patterns, activator treatment effects may be predicted during the diagnosis and treatment planning stage.

Sarcopenia: Nutrition and Related Diseases

  • Du, Yang;No, Jae Kyung
    • Culinary science and hospitality research
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    • v.23 no.1
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    • pp.66-78
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    • 2017
  • "Sarcopenia", sarcopenia is an old age syndrome, and used to describe the reduction of skeletal muscle. Initially, it was thought that sarcopenia was only a senile disease characterized by degeneration of muscle tissue. However, its cause is widely regarded as multifactorial, with neurological decline, hormonal changes, inflammatory pathway activation, declines in activity, chronic illness, fatty infiltration, and poor nutrition, all shown to be contributing factors. Skeletal muscle mass can be measured by a variety of methods, currently, the commonly used methods are dual-energy X-ray scanning (DXA), computer tomography (CT), magnetic resonance imaging (MRI), etc. Muscular skeletal disorders can also be assessed by measuring appendicular skeletal muscle (ASM), particularly muscle tissue content. At the same time, sarcopenia refers to skeletal muscle cell denervation, mitochondrial dysfunction, inflammation, hormone synthesis and secretion changes and a series of consequences caused by the above process and is a progressive loss of skeletal muscle syndrome, which can lead to the decrease of muscle strength, physical and functional disorders, and increase the risk of death. Sarcopenia is mainly associated with the aging process, but also related to other causes such as severe malnutrition, neurodegenerative diseases, and disuse and endocrine diseases associated with muscular dystrophy, and it is the comprehensive results of multi-factors, so it is difficult to define that sarcopenia is caused by a specific disease. With the aging problem of the population, the incidence of this disease is increasingly common, and seriously affects the quality of the life of the elderly. This paper reviews the etiology and pathogenesis of myopathy, screening methods and diagnosis, the influence of eating habits, etc, and hopes to provide reference for the diagnosis and treatment of this disease. At present, adequate nutrition and targeted exercise remain the gold standard for the therapy of sarcopenia.

THE EFFECT OF PRE-OPERATIVE MAXILLARY OCCLUSAL PLANE ANGLE TO POST-OPERATIVE SKELETAL STABILITY AFTER TWO-JAW SURGERY (수술 전 상악 교합평면각이 상하악 동시 수술 후 골격 안정성에 미치는 영향)

  • Choi, Youn-Mo;Ryu, Dong-Mok;Oh, Jung-Hwan
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.29 no.2
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    • pp.141-147
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    • 2007
  • The purpose of this study was to evaluate the effects of maxillary occlusal plane angle to postoperative skeletal stability by comparative analysis after two-jaw surgery of patients with skeletal CIII malocclusion. This study was made with lateral cephalometric radiography of 52 patients with skeletal class III malocclusion that were performed to Le Fort I osteotomy and BSSRO. And 52 patients were divided to Group A(n=30) and B(n=22). Maxillary posterior impaction was not conducted in Group A, which the pre-operative maxillary occlusal plane angle was in a normal range, and for Group B, which the pre-operative maxillary occlusal plane was low, the maxillary posterior impaction was conducted. The results were obtained as follows : 1. The relapse rate of Group A, which the pre-operative maxillary occlusal plane angle was in a normal range, was relatively stable compared to Group B, which the pre-operative maxillary occlusal plane was low. 2. The relapse rate of each measurement of Group B, which had the maxillary occlusal plane altered during the operation, was somewhat high, and of those, the post-operative relapse rate of overjet, overbite, mandibular plane angle appeared to be significantly high in the statistics. The analyzed results above, was thought to be indicating that the pre-operative maxillary occlusal plane angle was closely related to the post-operative skeletal stability, and that obtaining post-operative skeletal stability only through operative normalization of occlusal plane angle may meet limitations.

A Study on the Growth, Skeletal Maturity of Chidren with Low Weight (저체중 소아의 성장과 골성숙도에 관한 임상적 연구)

  • Kim, Cho-Young;Chang, Gyu-Tae
    • The Journal of Pediatrics of Korean Medicine
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    • v.24 no.2
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    • pp.147-158
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    • 2010
  • Objectives The study was designed to find out the relationships between low weight and growth, skeletal maturity among children by analyzing body composition and bone age. Methods Subjects were composed of 336 children from six years to seventeen years of age, without any other diseases related to growth, who visited the department of oriental pediatrics East West Neo Medical Center at Kyung Hee University and were measured their body composition and bone age. Results There were significant correlations between decreasing of RH-MPH(%) and low weight. 1. As obesity index decreased, the RH-MPH was also decreased. 2. The RH-MPH(%) of the low weight group according to the obesity index classification was significantly decreased than that of the normal weight group. 3. The skeletal maturity was more decreased in the low weight group. However, the differences between the two group was not significant. 4. The RH-MPH(%) was increased in children who developed secondary sexual character. Skeletal maturity was decreased in children who developed secondary sexual character. 5. The RH-MPH(%), and skeletal maturity was not significantly different between males and females. 6. Only in the case of children without development of secondary sexual character, low weight caused significant RH-MPH(%) decrease. Conclusions Low weight children might be smaller than what it supposed to be. Also, low weight could affect body development more to the children than to the teenager.

Effect of Low-Energy Laser Irradiation on the Proliferation and Gene Expression of Myoblast Cells (저출력 레이져 자극이 근육세포의 증식 및 유전자 발현에 미치는 효과)

  • Kwag, J.H.;Jeon, O.H.;Kang, D.Y.;Ryu, H.H.;Kim, K.H.;Jung, B.J.;Kim, C.H.
    • Journal of Biomedical Engineering Research
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    • v.31 no.1
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    • pp.81-86
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    • 2010
  • Laser irradiation is known to affect various tissues such as skin, bone, nerve, and skeletal muscle. Laser irradiation promotes ATP synthesis, facilitates wound healing, and stimulates cell proliferation and angiogenesis. In skeletal muscle, laser irradiation is related to the proliferation of skeletal muscle satellite cells. Normal skeletal muscle contains remodeling capacity from myogenic cells that are derived from mononuclear satellite cells. Their processes are activated by the expression of genes related with myogenesis such as muscle-specific transcription factors (MyoD and Myf5) and VEGF (vascular endothelial growth factor). In this study, we hypothesized that laser irradiation would enhance and regulate muscle cell proliferation and regeneration through modulation of the gene expressions related with the differentiation of skeletal muscle satellite cells. $C_2C_{12}$ myoblastic cells were exposed to continuous/non-continuous laser irradiation (660nm/808nm) for 10 minutes daily for either 1 day or 5 days. After laser irradiation, cell proliferation and gene expression (MyoD, Myf5, VEGF) were quantified. Continuous 660nm laser irradiation significantly increased cell proliferation and gene expression compared to control, continuous 808nm laser irradiation, and non-continuous 660nm laser irradiation groups. These results indicate that continuous 660nm laser irradiation can be applied to the treatment and regeneration of skeletal muscle tissue.

CEPHALOMETRIC MEASUREMENT ACCORDING TO SKELETAL MATURITY STAGE OF THE HAND AND WRIST (수완부골성숙단계에 따른 두부방사선계칙학적 연구)

  • Choi, Hae-Woon;Kim, Jae-Hyung
    • The korean journal of orthodontics
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    • v.17 no.1
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    • pp.135-148
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    • 1987
  • To investigate the relationship between craniofacial growth and bone maturity of the hand wrist in normal occlusion, the author took cephalogram and handwrist radiogram of 391 students (male 192, female 199) and assessed the measurements of cephalogram according to skeletal maturity stages of the hand and wrist. In this study, four skeketal stages and 36 linear, angular measurements of the cephalometrics were selected. In hand-wrist X-ray the bones used to determine skeletal maturity were the middle phalanges of the third finger, and distal epiphysis of the radius. In cephalogram, the landmark used to measure the angle and length were N, S, Po., Ar., Go., Me., Gn., Pog., Point B, Point A, ANS, PNS, Or., U1, L1, U6, L6 etc.. The results were as follows, 1. The table of mean, standard deviation, p-value from measurements were made in each group and both sex. 2. The increased measurements according to skeletal maturity were anterior cranial bese length, posterior cranial base length, ramus height, anterior facial height, posterior facial height, L1 to mandibular plane (mm), facial plane angle. In contrast to, decreased measurements were genial angle, facial cnvexity and facial plane angle. 3. Denture pattern measurements (IMPA, FMIA, occlusal plane to Go-Gn, interincisal angle, U1 to SN plane, U1 to SN plane, U1 to facial plane, L1 to facial plane etc.) .had nothing to do with skeletal maturity. 4. Skeletal maturity had close relationship with craniofacial growth, but had little to do with tooth development.

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