• 생약학회지
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• 제5권3호
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• pp.167-172
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• 1974

The stems of Aristolochia manshuriensis $K_{OMAROV}$ collected in Kang-won-do, Korea, have been shown to contain aristolochic acids I and II and debilic acid. ${\beta}-Sitosterol$ and the ester of linolic acid were isolated from the petroleum ether: ether(1 : 1) extracts of the stem by using column chromatography.

• 생약학회지
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• 제23권2호
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• pp.115-116
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• 1992

From the bulbs of Erythronium japonicum Decaisne(Liliaceae), ${\beta}-sitosterol$ and its $3-O-{\beta}-D-glucoside$ together with fatty acids were isolated. All compounds were identified on the basis of spectral data. Campesterol and stigmasterol were also identified as minor components. Paimitic acid was identified as a major component and stearic, oleic, arachidic, behenic, tricosanoic and lignoceric acids were also characterized as minor ones.

• Archives of Pharmacal Research
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• 제16권2호
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• pp.109-113
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• 1993

The dried unnipe fruits of Rubus sp. (Rubi Fructus, Bogabunja) have yielded $\beta$-sitosterol glucoside and four urs 12 en-28-oic acid derivatives, three of which were as their glucosiders. They were identified as 23-hydroxytomentic acid, rosamultin, niga-ichigosides $F_1\;and\;F_2$ on the basis of spectral data.

• 약학회지
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• 제27권1호
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• pp.37-43
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• 1983

The rhizome of Polygonum sachalinense Fr. Schm. (=Reynoutria sachalinensis Nakai, Polygonaceae) has been used as "Polygoni Rhizoma" (Hu Zhang) in the Orient as laxatives, diuretics and for treatment of suppurative dermatitis, gonorrhoea, favus and athlete's foot. From the methanolic extract of the dried rhizome physcion, emodin, emodin-8-O-$\beta$-D-glucoside as anthraquinone derivatives and .betha.-sitosterol glucoside were isolated and identified. Stilbene derivatives which have antibacterial and antifungal activities were also isolated.

• Archives of Pharmacal Research
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• 제6권1호
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• pp.29-33
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• 1983

From the roots of Pandia siamensis, D-mannitol, a mixture of .betha.-sitosterol and campesterol, oleanolic acid acetate, oleanolic acid-3-.alpha.-L-arabino side and mesembryanthemoidigenic acid as a sapogenin were isolated and characterized.

• 생약학회지
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• 제52권4호
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• pp.208-211
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• 2021

Four compounds were isolated from 90% ethanol extract of the stem of Clematis heracleifolia. On the basis of spectral data, the structure of isolated compounds were identified as sitosterone (1), β-sitosterol (2), scoparone (3) and octadecanoyl caffeate (4), respectively. Sitosterone (1) and octadecanoyl caffeate (4) are isolated from this plant for the first time.

• Food Science and Biotechnology
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• 제17권2호
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• pp.367-372
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• 2008

Cellular protection against carcinogens could be achieved by the induction of phase 2 detoxifying and antioxidant enzymes such as glutathione S-transferase (GST), NAD(P)H:quinone oxidoreductase 1 (NQO1) and heme oxygenase 1 (HO1). Nuclear transcription factor E2-related factor 2 (Nrf2) binds to antioxidant response element (ARE) in the promoter region of these genes and the resulting transactivation occurs. In the present study the effect of gujeolcho (Chrysanthemum zawadskii) roots on the Nrf2-ARE pathway were investigated. C. zawadskii root extract was fractionated with a series of organic solvents and their ability to induce Nrf2-ARE pathway was examined. We separated the most potent dichloromethane (DCM) fraction into 12 sub-fractions and found several sub-fractions with strong effects on the Nrf2-ARE pathway. Fraction 4 strongly induced the ARE-reporter gene activity as well as Nrf2 expression. Sitosterol was isolated as a major compound in fraction 4 although its activity was not as potent as its mother fraction. These results indicate that C. zawadskii roots might be used as a potential natural chemopreventive source.

• 한국식품과학회지
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• 제12권1호
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• pp.6-12
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• 1980

한국산(韓國産) 목이(木耳) 석의중(石衣中) 지방산(脂肪酸) 조성(組成)과 스테롤 성분(成分)의 구명(究明)을 G.L.C.와 I.R. 분석(分析)에 의하여 검토(檢討)한 결과(結果) 다음과 같은 결과(結果)를 얻었다. G.L.C에 의(依)한 지방산(脂肪酸의 조성(組成)은 목이(木耳)의 경우 linoleic acid 33.73, palmitic acid 15.52, stearic acid 5.03, oleic acid 16.03, linolenic acid 17.80 및 미지산(未知酸) 11.89%를 나타낸 반면(反面), 석의(石衣)는 linoleix acid 46.35, palmitic acid 31.71, oleic acid 16.82, 미지산(未知酸) 5.12% 및 소량(小量)의 stearic acid와 linolenic acid를 보여주었다. 스테롤 성분(成分)을 T.L.C.에 의(依)하여 분리(分離)한 후(後) I.R. 분석(分析)으로 구명(究明)한 결과(結果) 목이(木耳)와 석의(石衣) 모두 sitosterol과 ergosterol을 함유(含有) 하였다.

• 한국식품저장유통학회지
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• 제15권6호
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• pp.878-883
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• 2008

항균력이 탁월한 매실추출물로부터 항균활성물질을 column chromatography를 이용하여 순수하게 분리하고, nuclear magnetic resonance (NMR) spectrophtometer 측정기에 의하여 항균활성물질의 화학구조를 다음과 같이 분리 동정하였다. 즉, 매실추출물을 상온에서 메탄올에 현탁한 후, ethyl ether, ethyl acetate, n-butanol로 각각 분배 추출하여 각 용매의 수용성 추출물을 획득하였다. 각 용매의 수용성 추출물을 loading한 후, silica gel(70-230 mesh, Merck) column chromatography하여 소획분을 얻었다. 분리된 분획 중 항균력이 있는 소획분을 Sephadex LH 20을 충진하고 column chromatography하여 각 항균분획물질을 분리하였다. column chromatography에서 분리한 각 항균분획물질(Compound A, Compound B, Compound C)의 구조분석을 위해 $^{1}H$ 및 $^{13}C$ NMR 스펙트럼을 실온에서 측정하였다. NMR은 Bruker DRX500 (500MHz)을 이용하여 측정하였으며, 용매와 기준물질은 $CDCl_3$와 TMS를 각각 사용하였다. 이와같이 분리한 각 항균분획물질을 NMR 분석법으로 동정한 결과, isoeugenol, nomilin 및 $\beta$-sitosterol 등으로 확인되었다.

• 한국수산과학회지
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• 제15권1호
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• pp.94-98
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• 1982

낙동강 하류산 재첩 (Corbicula elatior)에 함유되어 있는 지질의 이화학적 성질, 조성 그리고 이 지질의 지방산과 sterol 조성을 밝히기 위하여 실험한 결과는 다음과 같다. (1) 조지질과 불연화물 함양은 각각 $2.17\%,\;16.6\%$였으며 요-드가는 119였다. (2) 조지질의 조성은 린지질이 약 $43\%$로 가장 많았고 triglyceride (약$40\%$), 유리 sterol ($11\%$)의 순이었다. (3) 지방기조성은 $C_{16:0}$가 $48.4\%$로 가장 많았고, C_{14:0}\;(10.0\%, C_{14:1}\;5.4\%,\;C_18:1 (5.3\%)의 순이였으며 $C_{19:0}$으로 생각되는 지방산이 $6.4\%$였다. (4) 6종의 sterol 이 검출되었는데 24-nlethylene-cholesterol이 $41\%$로 가장 많았고 $\beta-sitosterol(22.5\%)$, fucosterol이 $14.9\%$였으며 isofucosterol과 과 $\Delta^7-avenasterol (?)(5.2\%)$로 생각되는 것이 각각 $14.0\%$, $5.2\%$ 였고 cholesterol은 $2.3\%$로 가장 적었다.