• Journal of the Korean Geographical Society
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• v.29 no.3
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• pp.233-252
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• 1994

One of major advantages of Lumped model is its ability to simulate extended flows. A further advantage is that it requires only conventional, readily available hydrological data (rainfall, evaporation and runoff). These two advantages commend the use of this type of model for the analysis of the hydrological effects of landuse change. Experimental Catchment(K11) of Kimakia site in Kenga experienced three phases of landuse change for sixteen and half years. The Institute of Hydrology offered the hydrological data from the catchment for this research. On basis of Blackie's(l972) 9-parameter model, a new model(R1131) was reorganized in consideration of the following aspects to reflect the hydrological characteristics of the catchment: 1) The evapotranspiration necessary for the landuse hydrology, 2) high permeable soils, 3) small catchment, 4) input option for initial soil moisture deficit, and 5) othel modules for water budget analysis. The new model is constructed as a 11-parameter, 3-storage, 1-input option model. Using a number of initial conditions, the model was optimized to the data of three landuse phases. The model efficiencies were 96.78%, 97.20%, 94.62% and the errors of total flow were -1.78%, -3.36%, -5.32%. The bias of the optimized models were tested by several techniques, The extended flows were simulated in the prediction mode using the optimized model and the data set of the whole series of experimental periods. They are used to analyse the change of daily high and low-flow caused by landuse change. The relative water use ratio of the clearing and seedling phase was 60.21%, but that of the next two phases were 81.23% and 83.78% respectively. The annual peak flows of second and third phase at a 1.5-year return period were decreased by 31.3% and 31.2% compared to that of the first phase. The annual peak flow at a 50-year return period in the second phase was an increase of only 4.8%, and that in the third phase was an increase of 12.9%. The annual minimum flow at a 1.5-year return period was decreased by 34.2% in the second phase, and 34.3% in the third phase. The changes in the annual minimum flows were decreased for the larger return periods; a 20.2% decrease in the second phase and 20.9% decrease in the third phase at a 50-year return period. From the results above, two aspects could be concluded. Firstly, the flow regime in Catchment K11 was changed due to the landuse conversion from the clearing and seedling phade to the intermediate stage of pine plantation. But, The flow regime was little affected after the pine trees reached a certain height. Secondly, the effects of the pine plantation on the daily high- and low-flow were reduced with the increase in flood size and the severity of drought.

• Journal of the Korean Geographical Society
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• v.40 no.4 s.109
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• pp.428-440
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• 2005

There is currently no agreement among archaeologists, environmental historians, and paleoecologists as to the relative significance of pre- and post-Conquest human impact on the environments of Highland Mexico. This paper presents the results of pollen, microscopic charcoal, dung fungal spore, isotope, and magnetic susceptibility analyses on ca. 4m sediment core. The coring site is Hoya Rincon de Parangueo, one of the seven maar lakes in the Valle do Santiago. Amaranthaceae pollen, one of important disturbance indicators and Zea mays pollen obviously indicate two periods of agricultural activities. The first period begins ca. 400 B.C. and ends ca. A.D. 850. The second begins around A.D. 1550 and continues to the present. During the first period, the degree of agricultural activities was related to periodical sunspot cycles and the most intense activities were present between ca. A.D. 150-ca. A.D. 400. The abrupt increase of $\delta^{18}O$ around 280cm may reflect that an important transition to a dry phase took place around A.D. 450. People probably stopped cultivating crops due to dry conditions prevailing since ca. A.D. 450. The second period, the post-Conquest, exhibits a dramatic increase of sporormiella, dung fungal spores resulted fron the introduction of cattle. Low Poaceae frequency and charcoal production and high $\delta^{13}C$ values, magnetic susceptibility, and organic contents all indicate the arrival of the Spanish. Most importantly, it seems that mesquite (Prosopis juliflora) could have benefits from declined fire frequencies caused by cattle grazing. The study area is now entirely dominated by woody plants like mesquite, which clearly demonstrates that serious vegetation change occurred in the study area.

• Journal of Korean Society of Forest Science
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• v.87 no.2
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• pp.131-144
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• 1998

Understanding of the reasons why users in recreation settings select particular trails may provide useful information for effective recreation resources management. This study investigated the present use of the major trails in Mudeung-san Provincial Park and the major influential factors on trail selection. This study was conducted in Mudeung-san Provincial Park stretching over Hwasun-gun and Damyang-gun of Chonnam Province and Kwang-ju city during August in 1996. Data were collected through on-site survey and mail-back questionnaire. 519(44.2%) out of 1173 survey samples were used for analysis. Reasons for selecting a particular trail were classified into 8 major factors. In overall, the order of the importance degree of the factors was 1) aesthetics of landscape, 2) safety(from physical and crime), 3) conditions for health, 4) quietness, 5) familiarity, 6) on the way to the destination, 7) convenience/social, 8) others' intention. There were differences in the degree of importance of each factor depending on trails, users' characteristics(eg., gender, age, group size, visit experience, etc.) and users' behavioral patterns. Recreation motivations were classified into 5 major factors. The order of the importance degree of the factors was 1) contacting with nature, 2) self-training, 3) solitude, 4) social interaction, 5) appreciating cultural properties. Regardless of trails, 'contacting with nature' was the most important factor, and the degree of importance in the other 4 motivational factors showed only a little differences in order according to the trails. There were correlations between major factors for trail selection and recreation motivations. The results of this study may provide foundational information for establishing effective management strategies through better understanding of the present use of trails and influential factors on trail selection. It can be used for reducing the present social and ecological problems caused by use concentration on certain trails and providing users with better quality of diverse recreational experiences. This study discussed the findings, and suggested some management strategies based on these information.

• Microbiology and Biotechnology Letters
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• v.41 no.1
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• pp.17-25
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• 2013

The thermotolerant methylotrophic yeast Hansenula polymorpha is an attractive model organism for various fundamental studies, such as the genetic control of enzymes involved in methanol metabolism, peroxisome biogenesis, nitrate assimilation, and resistance to heavy metals and oxidative stresses. In addition, H. polymorpha has been highlighted as a promising recombinant protein expression host, especially due to the availability of strong and tightly regulatable promoters. In this study, we investigated the possibility of employing human serum albumin (HSA) as the fusion tag for the secretory expression of heterologous proteins in H. polymorpha. A set of four expression cassettes, which contained the methanol oxidase (MOX) promoter, translational HSA fusion tag, and the terminator of MOX, were constructed. The expression cassettes were also designed to contain sequences for accessory elements including His8-tag, $2{\times}(Gly_4Ser_1)$ linkers, tobacco etch virus protease recognition sites (Tev), multi-cloning sites, and strep-tags. To determine the effects of the size of the HSA fusion tag on the secretory expression of the target protein, each cassette contained the HSA gene fragment truncated at a specific position based on its domain structure. By using the Green fluorescence protein gene as the reporter, the properties of each expression cassette were compared in various conditions. Our results suggest that the translational HSA fusion tag is an efficient tool for the secretory expression of recombinant proteins in H. polymorpha.

• The Korean Journal of Pharmacology
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• v.32 no.1
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• pp.23-29
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• 1996

According to the traditional receptor model, competitive antagonists share with agonists the ability to bind to a common site on receptors, but they are different from agonist in that they cannot trigger the biological response-i.e., they lack intrinsic efficacy. Recent findings extend the model by indicating that not all antagonists display an intrinsic efficacy of zero but that some display 'inverse agonism'. In the present study we studied the inverse agonism at $A_1$ adenosine receptors in membranes prepared from rat cerebral cortex. Eight commercially available $A_1$ adenosine receptor antagonists (CGS-15943, ADPX, CPT, DPCPX, DPX, N-0840, PACPX and 8-PT) were screened for inverse agonism by measuring the extent of $[^{35}S]guanosine-5'-({\gamma}-thio)$ triphosphate $([^{35}S]GTP_{\gamma}S)$ binding to G proteins. The agonist-induced stimulation of $[^{35}S]GTP_{\gamma}S$ bindings was completely blocked in the presence of $A_1$ adenosine receptor antagonists. Under optimal conditions, two types of antagonists could be distinguished. Seven antagonists including DPCPX decreased the basal $[^{35}S]GTP_{\gamma}S$ binding in the absence of agonist, displaying inverse agonist activity. One (CGS-15943) had no effect on the basal bindings. N-ethylmaleimide treatment reduced the basal bindings as well as agonist-mediated stimulation of $[^{35}S]GTP_{\gamma}S$ bindings, indicating that a substantial amount of this binding reflects an activated state of the C proteins. In good agreement with these findings, 0.1 mM GTP decreased the apparent affinity of the receptors for the agonist PIA, increased that for DPCPX, and had no effect on that for CGS-15943.

• Journal of Environmental Impact Assessment
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• v.29 no.3
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• pp.157-181
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• 2020

Sediments from rivers, lakes and marine ports serve as end points for pollutants discharged into the water, and at the same time serve as sources of pollutants that are continuously released into the water. Until now, the contaminated sediments have been landfilled or dumped at sea. Landfilling, however, was expensive and dumping at sea was completely banned due to the London Convention. Therefore, this study applied contaminated sedimentation soil of 'Royal Palace Livestock Complex' as soil purification method. Soil remediation methods were applied to pretreatment, composting, soil washing, electrokinetics, and thermal desorption by selecting overseas application cases and domestically applicable application technologies. As a result of surveying the site for pollutant characteristics, Disolved Oxigen (DO), Suspended Solid (SS), Chemical Oxygen Demand (COD), Total Nitrogen (TN), and Total Phosphorus (TP) exceeded the discharged water quality standard, and especially SS, COD, TN, and TP exceeded the standard several tens to several hundred times. Soil showed high concentrations of copper and zinc, which promote the growth of pig feed, and cadmium exceeded 1 standard of Soil Environment Conservation Act. In the pretreatment technology, hydrocyclone was used for particle size separation, and the fine soil was separated by more than 80%. Composting was performed on organic and Total Petroleum Hydrocarbon (TPH) contaminated soils. TPH was treated within the standard of concern, and E. coli was analyzed to be high in organic matter, and the fertilizer specification was satisfied by applying the optimum composting conditions at 70℃, but the organic matter content was lower than the fertilizer specification. As a result of continuous washing test, Cd has 5 levels of residual material in fine soil. Cu and Zn were mostly composed of ion exchange properties (stage 1), carbonates (stage 2), and iron / manganese oxides (stage 3), which facilitate easy separation of contamination. As a result of applying acid dissolution and multi-stage washing step by step, hydrochloric acid, 1.0M, 1: 3, 200rpm, 60min was analyzed as the optimal washing factor. Most of the contaminated sediments were found to satisfy the Soil Environmental Conservation Act's standards. Therefore, as a result of the applicability test of this study, soil with high heavy metal contamination was used as aggregate by applying soil cleaning after pre-treatment. It was possible to verify that it was efficient to use organic and oil-contaminated soil as compost Maturity after exterminating contaminants and E. coli by applying composting.

• Journal of Hospice and Palliative Care
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• v.12 no.3
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• pp.139-146
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• 2009

This study was designed to examine the effect of aroma massage therapy on lower extremity edema of terminal cancer patients. Methods: A total of thirty-six terminal cancer patients with lower extremity edema were divided into two groups: the aroma massage group received massage with blending oil which was applied from toes to 10 cm above the knee of the subject for 15 to 20 minutes in each turn, while the control group received sham aroma massage (applied with carrier oil only). The circumferences of the fore-foot, ankle and calf were measured before massage and 30 minutes, 2 hours, and 12 hours after massage. The blood pressure, pulse and body temperature were also measured to find the change of subject's physiologic conditions. Results: There were no significant differences in blood pressure, heart rate, body temperature and lower extremity circumferences between two groups. However, edema at each site was slightly improved in the treatment group after the aroma massage therapy, compared to baseline data (P<0.05). In addition, the reduction of lower extremity circumference was maximal at 2 hours in foot, 30 min in right ankle and 12 hours in right calf after aroma massage therapy (P<0.05). Conclusion: Our results suggest that aroma massage therapy is not effective on the lower extremity edema of terminal cancer patients.

• Korean Journal of Ecology and Environment
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• v.42 no.3
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• pp.340-349
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• 2009

The natural type section of Gap Stream was divided into 7 sites, such as, closed pool, runs, riffle, opened pool, pool, reek-scattered riffle, and Dam-type pool. The ecological characteristics of fish community at each site was examined from April, 2007 to October, 2008. During the survey period, 29 species belonging to 8 families were collected, and Carassius auratus (St. 1), Coreoleuciscus splendidus (St. 3), Acheilognathus lanceolatus (St. 4) and Zacco platypus (St. 2, 5, 6, 7) were characteristic species that represent each habitat. The species of C. auratus preferred physical habitat with sand-bottom pool, moderate depth of 65$\sim$90 cm, and stagnant water. The species of C. splendidus mainly preferred physical habitat with cobbles and pebbles are scattered riffles (St. 3), moderate depth of 65$\sim$90 cm, and flow velocity is 0.14$\sim$0.85 m $sec^{-1}$. It also preferred where concentration of BOD, COD, TN, TP and SS is low and DO's value is high, because the flow velocity is fast. A. lanceolatus preferred where the depth of water is low (3$\sim$44 cm) like an opened pool (St. 4) and the flow velocity is slow (0.01$\sim$0.02 m $sec^{-1}$). Z. platypus dominated in a variety of habitats such as runs (St. 2), pool (St. 5), rock-scattered riffles (St. 6) and D-type pool (St. 7), and it preferred places where flow is abundant and riverbed structure is diverse. On the other hand, 4 individuals of Iksookimia choii appeared at reek-scattered riffles (St. 6). I. choii appeared in this research lived in where the width of river is 24 m, the depth of water is 3$\sim$35 cm and the flow velocity is 0.01$\sim$0.49 m $sec^{-1}$, and riverbed structure was diversely formed with boulder to sand. Also, water temperature, EC, BOD, COD, TN and TP was low, but concentrations of DO and SS were high comparatively. Therefore, it seems that I. choii can live only in physical and chemical environment with similar conditions.

• Journal of the Korean association of regional geographers
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• v.2 no.1
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• pp.25-38
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• 1996

As the proportion of women's participation in economic activities is rising, the increase of husband and wife both working and nuclear families makes children up-bringing a social problem. But many families have difficulties by the shortage of day nurseries which can solve it. As we can see in the research, the most urgent problem is the extension of nurseries in quantity. In Taegu, since it became a wide-area city, there are 473 nurseries. But in the respect of distribution, only less than 10% of Dongs have more than 7 nurseries and more than 90% of Dongs have less than 7 nurseries. Consequently nurseries are extremely insufficient. Moreover 29 Dongs don't have any nurseries at all and they take 18.6% of Dongs. The second problem is the unbalanced distribution of nurseries. West and north ward which are industrial complex and swarmed with low-income families, and Tal-sung county which is recently included in the wide-area city keenly need the establishment of nurseries. Besides, Bi-san 1 Dong and Non-gong which have only $1{\sim}2$ nurseries though they have high proportion of children and women who can be pregnant are also the areas which take precedence of nursery establishment. The third problem is that government support must be increased in the areas which have many small, petty and profit-making private nurseries so that good quality teachers can make breeding activities in nice facilities and environment. In materials which are obtained by the interviews with publich servants in charge of family welfare in some ward offices. Young and unexperienced persons who aquired certificate of qualification take day-nursery permits and run nurseries only a few months. and if the profits are insufficient, they sell the nurseries for premiums to third persons who are not qualified. Then the third managers only think of profits without thought of good quality childcare. As the result, the nurseries become asylums not nurseries. That is why the conditions of nursery establishment must be restricted to suitable scale and experienced persons. The fourth problem is that the nurseries in work places are extremely insufficient. The women who have jobs have many things to do before they go to work such as preparing meals and leaving children in the care of someone. Hence the childcare problem of working women must be solved. In nuclear families, childcare is the most serious problem for working women. The fifth one is the reduction of childcare expenses. Women must sacrifice themselves a lot to make social activities. To say nothing of physical and mental burden, they have to spend much of their salaries on childcare. And yet they don't take the benefit of good quality childcare. For the participation of women in public affairs, society must support the childcare problem to have then be devoted to their jobs without worries about their children. Therefore Taegu wide-area city must select west, north ward which are industrial complex and the low-income swarmed area before everything and establish many national, public and corporate nurseries which cost less expenses.

• Journal of Food Hygiene and Safety
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• v.25 no.2
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• pp.162-169
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• 2010

The compulsory beef labelling system has launched from January 1st 2007 by the amended Food Hygiene Law, we were checked the actual conditions of beef origin with a nationwide scale by the Hanwoo differentiation specific test method which was developed by Korea FDA using 90 SNP biomarkers. The test method is useful tool to differentiate the beef origin carrying out the mission of KFDA's annual food safety management guidance. Also we have technically transferred the Hanwoo differentiation specific test method to other institutes as well regional KFDA and established the training program as a regular course in Korea Human Resource Development Institute for Health and Welfare. The beef used in this study were collected according to the 2009 Food safety guidance in roast beef restaurants where business site area greater than 100 $m^2$. Total 216 samples were consisted of 48 samples of the Seoul area and 168 of the region. The monitoring result from restaurants in all the region of Korea showed that 3 of 216 Hanwoo-labelled beefs were found out as a non-Hanwoo (1.3%). This results are gradually deceasing trend compared with 34.0% in 2005, 30.1% in 2006, 3.2% in 2007 and 5.14% in 2008. From these data, the Hanwoo differentiation specific test method on the settlement of the compulsory beef labelling system has an important role. As a outcome of this project, we might be considered the early settlement of the compulsory beef labelling system, technically transferred to other institutes and the establishment of regular training program of the test method.