• Journal of Institute of Control, Robotics and Systems
• /
• v.12 no.6
• /
• pp.547-553
• /
• 2006

This paper studies digital control of biodynamic model of HIV-1 via intelligent digital redesign (IDR). The purpose of the IDR is to develop an equivalent digital fuzzy controller maintaining the satisfactory performance of an existing continuous-time fuzzy controller in the sense of the state-matching. Some conditions for the stability as well as the global state-matching are provided.. They are given by the form of the linear matrix inequalities (LMIs) and thereby easily tractable by the convex optimization techniques. The main features of the proposed method are that 1) the generalized control scheme is provided for the multirate as well as the single-rate digital controllers; 2) a new compensated block-pulse function method is applied to closely match the states of the continuous-time and the sampled-data fuzzy systems in the discrete-time domain; 3) the two-step procedure of IDR is presented to prevent the performance degradation caused by the additional stability conditions. The applicability of the proposed approach is shown through the biodynamic model of HIV-1.

• Nuclear Engineering and Technology
• /
• v.17 no.4
• /
• pp.279-289
• /
• 1985

The purpose of this paper is to investigate the density-wave oscillation type instability in the recirculating loop of U-tube steam generator (UTSG). The perturbed and nodalized conservations equations based on the drift-flux model have been derived to obtain the single-and two-phase pressure drop perturbations, by taking into account the slip between phases, nonuniform heat flux and heated wall dynamics. To assess the stability, the frequency domain technique with the Nyquist criterion has been used under the constant pressure drop boundary condition through the loop. The computer implementation of this model, SASG, was used for the parametric study of the steam generator in Kori-Unit 1. The results of the parametric study revealed important factors influencing UTSG stability margin.

• Nuclear Engineering and Technology
• /
• v.54 no.8
• /
• pp.2828-2839
• /
• 2022

This study developed a safety assessment tool for geological disposal systems called APro, a systemically integrated modeling system based on modularizing and coupling the processes which need to be considered in a geological disposal system. Thermal, hydraulic, chemical, canister failure, radionuclide release and transport processes were considered in the current version of APro. Each of the unit processes in APro consists of a single Default Module, and several Alternative Modules which can increase the flexibility of the model. As an initial stage of developing the modularization concept and modeling interface, the Default Modules of each unit process were described, with one Alternative Module of chemical process. The computation part of APro is mainly a MATLAB workspace controlling COMSOL and PHREEQC, which are coupled by an operator splitting scheme. The APro model domain is a stylized geological disposal system employing the Swedish disposal concept (KBS-3 type), but the repository layout can be freely adjusted. In order to show the applicability of APro to the total system performance assessment of geological disposal system, some sample simulations were conducted. From the results, it was confirmed that coupling of the thermal and hydraulic processes and coupling of the canister failure and the radionuclide release processes were well reflected in APro. In addition, the technical connectivity between COMSOL and PHREEQC was also confirmed.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.16 no.10
• /
• pp.3211-3229
• /
• 2022

To solve the problems existing in the process of Weibo disaster rumor recognition, such as lack of corpus, poor text standardization, difficult to learn semantic information, and simple semantic features of disaster rumor text, this paper takes Sina Weibo as the data source, constructs a dataset for Weibo disaster rumor recognition, and proposes a deep learning model BERT_AT_Stacked LSTM for Weibo disaster rumor recognition. First, add adversarial disturbance to the embedding vector of each word to generate adversarial samples to enhance the features of rumor text, and carry out adversarial training to solve the problem that the text features of disaster rumors are relatively single. Second, the BERT part obtains the word-level semantic information of each Weibo text and generates a hidden vector containing sentence-level feature information. Finally, the hidden complex semantic information of poorly-regulated Weibo texts is learned using a Stacked Long Short-Term Memory (Stacked LSTM) structure. The experimental results show that, compared with other comparative models, the model in this paper has more advantages in recognizing disaster rumors on Weibo, with an F1_Socre of 97.48%, and has been tested on an open general domain dataset, with an F1_Score of 94.59%, indicating that the model has better generalization.

• Journal of the Society of Naval Architects of Korea
• /
• v.59 no.3
• /
• pp.141-148
• /
• 2022

A hybrid turbulence model has developed by combining a sub-grid scale model using dynamic k equation in LES with k-𝜔 SST model of RANS equation. To ascertain potential applicability of the hybrid turbulence model, fully developed turbulent channel flows at Re_𝜏=180 have been simulated of which computational domain has a top wall with coarse cells and a bottom wall with fine cells. The streamwise mean velocity and turbulent intensity profiles showed a good agreement with DNS data when using the hybrid model rather than using a single model in k-𝜔 SST or dynamic k equation models. Computational simulations of turbulent flows around KVLCC2 with a pre-swirl duct have been mainly performed using the hybrid turbulence model. Compared to the results obtained from RANS simulation with k-𝜔 SST model as well as LES with dynamic k equation SGS model, turbulent wakes of the duct in the present simulation using the hybrid turbulence model were very similar to that of LES. Also, the resistances acting on hull, rudder and duct in hybrid turbulence model were similar to those in RANS simulation whereas the viscous forces acting on the hull in LES had a significant error due to coarse cells inappropriate to the sub-grid scale model.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.7
• /
• pp.2713-2717
• /
• 2015

Background: Possible associations between the single nucleotide polymorphism (SNP) rs8034191 in the aminoglycosidephosphotransferase domain containing 1 (AGPHD1) gene and lung cancer risk have been studied by many researchers but the results have been contradictory. Materials and Methods: A computerized search for publications on rs8034191 and lung cancer risk was performed. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess the association between rs8034191 and lung cancer risk with 13 selected case-control studies. Sensitivity analysis, test of heterogeneity, cumulative meta-analysis, and assessment of bias were also performed. Results: A significant association between rs8034191 and lung cancer susceptibility was found using the dominant genetic model (OR=1.344, 95% CI: 1.285-1.406), the additive genetic model (OR=1.613, 95% CI: 1.503-1.730), and the recessive genetic model (OR=1.408, 95% CI: 1.319-1.503). Moreover, an increased lung cancer risk was found with all genetic models after stratification of ethnicity. Conclusions: The association between rs8034191 and lung cancer risk was significant using multiple genetic models, suggesting that rs8034191 is a risk factor for lung cancer. Further functional studies of this polymorphism and lung cancer risk are warranted.

• Journal of Korea Society of Industrial Information Systems
• /
• v.24 no.5
• /
• pp.17-25
• /
• 2019

In this paper, we introduce the technology to convert a single human image into a fashion show animation video clip. The technology can help the customers confirm the dynamic fitting result when combined with the virtual try on technique as well as the interesting experience to a normal person of being a fashion model. We developed an extended technique of full human 2D to 3D inverse modeling based on SMPLify human body inverse modeling technique, and a rigged model animation method. The 3D shape deformation of the full human from the body model was performed by 2 part deformation in the image domain and reconstruction using the estimated depth information. The quality of resultant animation videos are made to be publically available for evaluation. We consider it is a promising approach for commercial application when supplemented with the post - processing technology such as image segmentation technique, mapping technique and restoration technique of obscured area.

• The KIPS Transactions:PartA
• /
• v.14A no.7
• /
• pp.399-408
• /
• 2007

Currently various techniques for efficiently developing sensor network applications are developed. However, these techniques provide the method for developing only single sensor network application easily and rapidly. Since sensor network applications control various sensor nodes based on core components of operating system, the technique to develop applications by defining common functionalities of various applications and selecting variable functionalities according to the work flow of specific application is efficient. Accordingly, this paper presents an experimental study that identifies commonality of sensor network application domain and supports optional development according to the variability of application by applying product line approach to developing sensor network application. Through the experimental study, we describe the characteristics of sensor network application domain compared with general business domain for product line development. Also, we show the effectiveness of the proposed approach by presenting that core assets designed using the proposed variability feature model and VEADL are reused according to the functionalities of each sensor node.

• Journal of Microbiology and Biotechnology
• /
• v.19 no.11
• /
• pp.1306-1318
• /
• 2009

The filamentous ascomycete Sclerotinia sclerotiorum is well known for its ability to produce a large variety of hydrolytic enzymes. Two $\alpha$-amylases ScAmy54 and ScAmy43 predicted to play an important role in starch degradation were showed to produce specific oligosaccharides essentially maltotriose that have a considerable commercial interest. Primary structure of the two enzymes was established by N-terminal sequencing, MALDI-TOF masse spectrometry and cDNA cloning. The two proteins have the same N-terminal catalytic domain and ScAmy43 derived from ScAmy54 by truncation of 96 amino acids at the carboxyl-terminal region. Data of genomic analysis suggested that the two enzymes originated from the same $\alpha$-amylase gene and that truncation of ScAmy54 to ScAmy43 occurred probably during S. sclerotiorum cultivation. The structural gene of Scamy54 consisted of 9 exons and 8 introns, containing a single 1,500-bp open reading frame encoding 499 amino acids including a signal peptide of 21 residues. ScAmy54 exhibited high amino acid homology with other liquefying fungal $\alpha$-amylases essentially in the four conserved regions and in the putative catalytic triad. A 3D structure model of ScAmy54 and ScAmy43 was built using the 3-D structure of 2guy from A. niger as template. ScAmy54 is composed by three domains A, B, and C, including the well-known $(\beta/\alpha)_8$ barrel motif in domain A, have a typical structure of $\alpha$-amylase family, whereas ScAmy43 contained only tow domains A and B is the first fungal $\alpha$-amylase described until now with the smallest catalytic domain.

• The Journal of Information Systems
• /
• v.3
• /
• pp.71-82
• /
• 1994

Knowledge acquisition, maintenance of knowledge base, and validation and verification of knowledge are the addressed bottlenecks of building successful knowledge based systems. Along with the increment of interesting in the knowledge based systems, the organization needs to develop a new one although it has a similar one. This causes several serious problems including knowledge redundancy and maintenance of knowledge base. This paper present three models of the reusable knowledge base which might be the solution to the above problem. Three models are : 1) multiple knowledge bases for a single AI application, 2) multiple knowledge bases for multiple AI applications, 3) a single knowledge base for multiple AI applications. A new approach to build such a reusable knowledge base in a homogeneous environment is presented. Our model combines the essential object-oriented techniques with rules in a consistent manner. Important aspects of applying object-oriented techniques to AI are discussed (inheritance, encapsulation, message passing), and some potential problems in building an AI application (decomposition technique of knowledge, search time, and heterogeneous environment) are pointed out. The models of a reusable knowledge base provide several amenities : 1) reduce the knowledge redundancy, 2) reduce the effort of maintenance of the knowledge base, 3) reuse the resource of the multiple domain knowledge bases, 4) reduce the development time.