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Patient Severity Classification in a Medical ICU using APACHE Ⅲ and Patient Severity Classification Tool (APACHE Ⅲ를 이용한 중환자 분류도구의 타당도 검증)

  • Lee, Gyeong-Ok;Sin, Hyeon-Ju;Park, Hyeon-Ae;Jeong, Hyeon-Myeong;Lee, Mi-Hye;Choe, Eun-Ha;Lee, Jeong-Mi;Kim, Yu-Ja;Sim, Yun-Gyeong;Park, Gwi-Ju
    • Journal of Korean Academy of Nursing
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    • v.30 no.5
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    • pp.1243-1253
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    • 2000
  • The purpose of this study was to verify the validity of the Patient Severity Classification Tool by examining the correlations between the APACHE Ⅲ and the Patient Severity Classification Tool and to propose admission criteria to the ICU. The instruments used for this study were the APACHE Ⅲ developed by Knaus and the Patient Severity Classification Tool developed by Korean Clinical Nurses Association. Data was collected from the 156 Medical ICU patients during their first 24 hours of admission at the Seoul National University Hospital by three trained Medical ICU nurses from April 20 to August 31 1999. Data were analyzed using the frequency, $x^2$, Wilcoxon rank sum test, and Spearman rho. There was statistically significant correlations between the scores of the APACHE III and the Patient Severity Classification Tool. Mortality rate was increased as patients classification of severity in both the APACHE III and the Patient Severity Classification Tool scored higher. The Patient Severity Classification Tool was proved to be a valid and reliable tool, and a useful tool as one of the severity predicting factors, ICU admission criteria, information sharing between ICUs, quality evaluations of ICUs, and ICU nurse staffing.

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Glutathione Sulphydryl Contents and Antioxidant Activities of Lactobacillus spp. and Bacillus coagulans (Lactobacillus spp.와 Bacillus coagulans의 Glutathione Sulphydryl 함유율과 황산화 활성)

  • Byun, Jeong-Yeol;Yoon, Yeong-Ho
    • Journal of Dairy Science and Biotechnology
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    • v.22 no.2
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    • pp.91-97
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    • 2004
  • The antioxidative ability on the basis of reduced glutathione sulphydryl(GSH) level, the inhibition activities of linoleic acid peroxidation of cell free extract of Lactobacillus spp. and Bacillus spp. have been determined; Lactobacillus casei CU4114 contained the highest level of GSH among the probiotic strains with 25.15 ${\mu}$mole/g. Significantly high level of GSH occured in the intracellular cell free extract of Lactobacillus rhamnosus CU4201, Lactobacillus plantarum CU4203. The antioxidant activity and inhibition of linoleic acid peroxidation of cell free extract of Lactobacillus spp. and Bacillus spp. by thiobarbituric acid(TBA) assay have been shown to be significantly differed depending on the strains(P>0.01). Intracellular cell free extracts of L. acidophilus CU4111, L. casei CU4114, and strains of Bacillus coacillus revealed a significantly intensive inhibitory activity in the linoleic acid peroxidation reactions. Spearmans' rank correlation between inhibitory activity on linoleic acid peroxidation and cellular GSH levels of Lactobacillus spp. was analysed and the correlation quotient was 0.65 which means a significant positive correlation.

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The Effect of Vocal Hygiene for the Female Elementary School Teachers (초등학교 여교사를 대상으로 한 음성위생법 효과성)

  • Park, Sung-Shin;Sim, Hyun-Sub;Chung, Sung-Min;Park, Young-Hak;Cho, Seung-Ho
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.15 no.1
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    • pp.27-30
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    • 2004
  • Background and Objectives : The purpose of the present study is to investigate the effect of vocal hygiene education for the female elementary school teachers. Materials and Method : Thirty healthy female elementary school teachers were enrolled for the study. We provided a vocal hygiene education to the half of them. Voice handicap index and acoustic parameters were measured before and 4 week after the education. The efficacy of vocal hygiene education was analyzed by Wilcoxon Signed-rank test. Results : The vocal hygiene group showed significant improvement both in the subjective and objective data after the education. However, the non-vocal hygiene group failed to show any improvement. In functional score, emotional score, jitter, shimmer, only Junior Class(JC) could find significant after the education. Only low career(LC) could find significant in subjective data. Conclusion : Vocal hygiene education may be useful in reducing vocal misuse and abuse associated with teaching, and can be an effective method to maintain and improve the vocal health of teachers.

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Clinical changes of TMD and condyle stability after two jaw surgery with and without preceding TMD treatments in class III patients

  • Yoon, Sang-Yong;Song, Jae-Min;Kim, Yong-Deok;Chung, In-Kyo;Shin, Sang-Hun;Pusan Korea Pusan National University
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.37
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    • pp.9.1-9.7
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    • 2015
  • Background: This study are to identify the symptomatic changes and condylar stability after 2 jaw surgery without preceding treatments for Temporomandibular joints(TMJ) in class III patients with the TMJ symptoms; and to assess therapeutic effect of 2 jaw surgery and the necessity of preceding treatment for alleviation of TMJ symptoms. Methods: 30 prognathic patients with preexisting TMJ symptoms were divided into 2 groups according to presence or absence of preceding treatments before the surgery. We evaluated symptomatic changes on both TMJ by questionnaires and clinical examinations. And we reconstructed 3D cone beam computed tomography images before 2 jaw surgery, immediately after the surgery, and 6 months or more after the surgery with SimPlant software, and analyzed the stability of condylar position on 3D reconstruction model. Significances were assessed by the Wilcoxon signed rank test on SPSS ver. 20.0. Results: Both groups had favorable changes of TMJ symptoms after orthognathic surgery. And postoperative position of condyle had good stability during follow-up period. Conclusion: 2 jaw surgery without preceding treatments for TMD can have therapeutic effect for TMD patients with class III malocclusion.

Academic Achievement, Self-directed Learning, and Critical Thinking Disposition According to Learning Styles of Nursing Students (일 대학 간호대학생의 학습유형에 따른 학업성취도, 자기주도적 학습능력 및 비판적 사고성향)

  • Yang, Sun-Hee;Ha, Eun-Ho;Lee, Og-Cheol;Sim, In-Ok;Park, Young-Mi;Nam, Hyun-A;Kim, Jeong-Sook
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.19 no.3
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    • pp.334-342
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    • 2012
  • Purpose: This descriptive study was done to identify the academic achievement, self-directed learning (SDL), and critical thinking disposition (CTD) of nursing students according to their learning styles. Method: The participants were 240 nursing students. Data were collected using structured questionnaires which included Kolb's Learning Style Inventory, Academic Achievement in Fundamental Nursing and Health Assessment, Self Directed Learning Readiness Scale, and California Critical Thinking Disposition Inventory. Data were analyzed using ${\chi}^2$ test, ANOVA, Pearson' correlation coefficients, and Spearman rank correlation coefficient. Results: One third of respondents were shown to be Convergers in their learning style (33.3%). The Academic Achievement of students who were Convergers was significantly higher than those who were Divergers or Accommodators (F=5.95, p=.001). The SDL and CTD of students who were Convergers were significantly higher than Divergers and Assimilators (F=9.67, p<.001 and F=8.42, p<.001). No significant correlations were found between Academic Achievement and SDL or CTD, but a statistically significant positive correlation was found between SDL and CTD (r=.68, p<.001). Conclusion: The findings of this study indicate that learning style influences academic achievement, SDL and CTD.

Effect of Sequential Embryo Transfer in vitro Fertilization (체외수정시술시 Sequential ET의 효용성에 관한 연구)

  • Jung, Byeong-Jun;Kim, Jong-Sik;Song, Hyun-Jin
    • Clinical and Experimental Reproductive Medicine
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    • v.27 no.1
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    • pp.75-81
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    • 2000
  • Objective: The objective of this study is to influence of sequential embryo transfers in an invitro fertilization was examined. Method: After in vitro fertilization, a maximum of 6 fertilized oocytes was enrolled in this study. At day 3 after an oocytes retrieval, embryos with good quality were transferred (mean 4.9), remaining embryos (mean 2.0/cycle) were cryopreserved at blastocyst stage (Group 1). At day 5 after oocytes collection, second a embryo transfer (mean 1.2/cycle) was performed, if one of these embryos had reached the blastocyst stage (Group 2) using P1 supplemented with 10 SSS and 30% Follicular fluid. No statistical difference in the pregnancy rate could be seen between the group without a second embryo transfer (n=21; 28.6%) and the group with a second transfer (n=52; 28.8%). Results: The incidence of multiple pregnancy rate per embryo transfer was not statistically different between both group and no high-rank multiple pregnancy (greater than triplete) were observed (0.9%, 15.4%, respectively, p=0.74, ${\chi}^2$). Out of 114 cycles (506 embryos) cultured embryos in group 2, 52 cycles (159 embryos, 29.8%) reached the blastocyst stage. Conclusion: The second transfer did not have a significant effect on the pregnancy rate. The most important factor for the pregnancy seems to be the quality of the embryos transferred on day 3 following oocyte retrieval. We recommend embryo transfer is performed only one, day $2{\sim}3$ or D5.

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Change of Bone Mineral Density after Kirindiet therapy in Middle-Aged Obese Women under Normal Bone Mineral Density (정상골밀도이하 중년비만여성환자의 기린다이어트시 골밀도 변화)

  • Choi, Young-Min;Sim, Woo-Jin;Kim, Kil-Soo;Yoon, Yoo-Sik;Shin, Seung-Uoo
    • Journal of Korean Medicine for Obesity Research
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    • v.5 no.1
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    • pp.47-56
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    • 2005
  • Objectives : This study was performed to investigate the change of bone mineral density(BMD) after 1 month Kirindiet therapy including very low calory diet(VLCD) in middle-aged obese women$(65>age{\geqq}40,\;BMI{\geqq}25)$ under normal $BMD(T-score{\leqq}0)$. Methods : We examined body weight, body fat, protein mass and BMD of 13 middle-aged obese women who visited to Kirin Oriental Hospital from Sep. 7. 2004 to Oct. 12. 2005 before and after 1 month Kirindiet therapy. Body weight, body fat and protein mass was checked by Inbody 4.0 and BMD was checked by quantitated computed tomography. Wilcoxon signed rank test was used for analyzing changes of body weight, body fat, protein mass and BMD before and after treatment. Results : Alter 1 month treatment body weight(-4.89Kg, -6.74%, p=0.001), body fat(-3.47Kg, p=0.001) and protein mass(-0.97Kg, p=0.006) was significantly reduced. BMD was significantly increased in all cases(+4.87mg/cc, +4.16%, p=0.001). Though body weight, body fat and protein mass were significantly reduced, BMD was significantly increased(p<0.01). Conclusions : In this study, we can conclude that after 1 month Kirindiet therapy including VLCD, BMD in middle-aged obese women under normal BMD was significantly increased inspite of reduction of body weight, body fat and protein mass.

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A Ranking Method for Improving Performance of Entropy Coding in Gray-Level Images (그레이레벨 이미지에서의 엔트로피 코딩 성능 향상을 위한 순위 기법)

  • You, Kang-Soo;Sim, Chun-Bo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.4
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    • pp.707-715
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    • 2008
  • This paper proposes an algorithm for efficient compression gray-level images by entropy encoder. The issue of the proposed method is to replace original data of gray-level images with particular ranked data. For this, first, before encoding a stream of gray-level values in an image, the proposed method counts co-occurrence frequencies for neighboring pixel values. Then, it replaces each pay value with particularly ranked numbers based on the investigated co-occurrence frequencies. Finally, the ranked numbers are transmitted to an entropy encoder. The proposed method improves the performance of existing entropy coding by transforming original gray-level values into rank based images using statistical co-occurrence frequencies of gray-level images. The simulation results, using gray-level images with 8-bits, show that the proposed method can reduce bit rate by up to 37.85% compared to existing conventional entropy coders.

Locally Advanced, Unresectable Pancreatic Cancer Treated by Stereotactic Radiation Therapy (국소적으로 진행된, 절제 불가능한 췌장암에서 정위 방사선 치료)

  • Choi Chul-Won;Kim Mi-Sook;Cho Chul-Koo;Yoo Seong-Yul;Yang Kwang-Mo;Yoo Hyung-Jun;Lee Dong-Han;Ji Young-Hoon;Han Chul-Ju;Kim Jin;Kim Young-Han
    • Radiation Oncology Journal
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    • v.24 no.1
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    • pp.11-20
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    • 2006
  • Puroose: In order to find out whether stereotactic radiation therapy (RT) using CyberKnife (CK) could improve survival rate and lower acute toxicity compared to conventional RT. Materials and Methods: From April 2003 through April 2004, 19 patients with Eastern Cooperative Oncology Group (ECOG) performance status ${\leq}3$ and locally advanced pancreas cancer without distant metastasis, evaluated by CT or PET/CT, were included. We administered stereotactic RT consisting of either 33 Gy, 36 Gy or 39 Gy in 3 fractions to 6, 4 and 9 patients, respectively, in an effort to increase the radiation dose step by step, and analyzed the survival rate and gastrointestinal toxicities by the acute radiation morbidity criteria of Radiation Therapeutic Oncology Group (RTOG). Prognostic factors of age, sex, ECOG performance score, chemotherapy, bypass surgery, radiation dose, CA 19-9, planning target volume (PTV), and adjacent organ and vessel invasion on CT scan were evaluated by Log Rank test. Results: The median survival time was 11 months with 1-year survival rate of 36.8%. During follow-up period (range $3{\sim}20$ months, median 10 months), no significant gastrointestinal acute toxicity (RTOG grade 3) was observed. In univariate analysis, age, sex, ECOG performance score, chemotherapy, bypass surgery, radiation dose, CA 19-9 level, and adjacent organ and vessel invasion did not show any significant changes of survival rate, however, patients with PTV (80 cc showed more favorable survival rate than those with PTV>80 cc (p-value<0.05). In multivariate analysis, age younger than 65 years and PTV>80 cc showed better survival rate. Conclusion: In terms of survival, the efficacy of stereotactic radiation therapy using CK was found to be superior or similar to other recent studies achieved with conventional RT with intensive chemotherapy, high dose conformal RT, intraoperative RT (IORT), or intensity modulated RT (IMRT). Furthermore, severe toxicity was not observed. Short treatment time in relation to the short life expectancy gave patients more convenience and, finally, quality of life would be increased. Consequently, this could be regarded as an effective novel treatment modality for locally advanced, unresectable pancreas cancer. PTV would be a helpful prognostic factor for CK.

Kinetic of Catalytic CO2 Gasification for Cyprus Coal by Gas-Solid Reaction Model (기-고체 반응모델을 이용한 Cyprus탄의 CO2 저온촉매가스화 반응거동)

  • Hwang, Soon Choel;Lee, Do Kyun;Kim, Sang Kyum;Lee, Si Hyun;Rhee, Young Woo
    • Korean Chemical Engineering Research
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    • v.53 no.5
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    • pp.653-662
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    • 2015
  • In general, the coal gasification has to be operated under high temperature ($1300{\sim}1400^{\circ}C$) and pressure (30~40 bar). However, to keep this conditions, it needs unnecessary and excessive energy. In this work, to reduce the temperature of process, alkali catalysts such as $K_2CO_3$ and $Na_2CO_3$ were added into Cyprus coal. We investigated the kinetic of Cyprus char-$CO_2$ gasification. To determine the gasification conditions, the coal (with and without catalysts) gasified with fixed variables (catalyst loading, catalytic effects of $Na_2CO_3$ and $K_2CO_3$, temperatures) by using TGA. When catalysts are added by physical mixing method into Cyprus coal the reaction rate of coal added 7 wt% $Na_2CO_3$ is faster than raw coal for Cyprus char-$CO_2$ gasification. The activation energy of coal added 7 wt% $Na_2CO_3$ was calculated as 63 kJ/mol which was lower than raw char. It indicates that $Na_2CO_3$ can improve the reactivity of char-$CO_2$ gasification.