• Journal of the Korean Institute of Telematics and Electronics
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• v.27 no.2
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• pp.31-38
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• 1990

An antenna gain measurement system using an extrapolation technique is described. The technique is similar to the usual two-antenna method for absolute gain measurement system, but involves the measurement of the received signal as a function of seperation in short distances, and the signal-versus-seperation data is processed in a way that allows an extrapolation of the signal to "infinite" seperation. In this technique it is possible to obtain the near field gain as function of distance by combining the far field gain and a proximity correction factor. The results of gain measurements of standard gain horn antennas and OEG (open ended waveguide) antennas are also presented.

• Journal of Magnetics
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• v.18 no.4
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• pp.422-427
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• 2013

The aim of this study was to investigate effects of the number of acquisitions (NEX) on signal-to-noise (SNR) and artifacts in SENSE parallel imaging of magnetic resonance imaging (MRI). 3.0T MR System, 8 Channel sensitivity encoding (SENSE) head coils were used along with an in-vivo phantom. Reference sequence of 3D fast field echo (FFE) was consisted of NEX values of 2, 4, 6, 8, 10 and 12. The T2 turbo spin echo (TSE) sequence used for exams achieved SENSE factors of 1.2, 1.5, 1.8, 2.0, 2.2, 2.5, 2.8, 3.0, 3.2, 3.5, 3.8 and 4.0. Exams were conducted five times for each SENSE factor to measure signal intensity of the object, the posterior phase-encode direction and frequency direction. And SNR was calculated using mean values. SENSE artifacts were identified as background signal intensity in the phase-encoded direction using MRIcro. It was found that SNR increased but SENSE artifacts reduced with NEX of 4, 8 and 12 when the NEX increased in reference scan. It is therefore concluded that image quality can be improved with NEX of 4, 8 and 12 for reference scanning.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1527-1534
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• 2010

The conventional peptide modification process of guanidination, in which the amino groups of lysine residues are converted to guanidino groups using O-methylisourea to create more basic homoarginine residues, is often used to improve the signal intensity of lysine-containing peptides in matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). Here, we used three different protease enzymes (trypsin, Lys-C, and Glu-C) to evaluate the effects of guanidination on the MS signals of two enzymatically digested proteins. Horse heart myoglobin and bovine serum albumin were guanidinated either before or after digestion with trypsin, Lys-C, or Glu-C. The resulting peptides were subjected to MALDI-MS, and signal intensities and sequence coverage were systematically evaluated for each digest. Guanidination prior to Glu-C digestion improved sequence coverage for both proteins. For myoglobin, guanidination before enzymatic digestion with trypsin or Lys-C also enhanced sequence coverage, but guanidination after enzymatic digestion enhanced sequence coverage only with Lys-C. For albumin, guanidination either before or after Glu-C digestion increased sequence coverage, whereas pre- or post-digestion guanidination decreased sequence coverage with trypsin and Lys-C. The amino acid composition of a protein appears to be the major factor determining whether guanidination will enhance its MALDI-MS sequence coverage.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.346-349
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• 2017

Digital image processing is widely used in a variety of areas, and noise elimination is used as the preprocessing in all the image processing processes. Degradation is occurred in the image data due to multiple reasons. Degradation is to add the noise in the image signal, and salt and pepper noise is the representative one to cause degradation. Therefore, image restoration algorithm was proposed to process with histogram weight filter and median filter by the noise density of local mask to restore the damaged image in the salt and pepper noise environment, in this article. In addition, it was compared with the existing methods using peak signal to noise ratio(PSNR) as the objective determination factor of improvement effect.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.55 no.7
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• pp.265-272
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• 2006

This paper describes a method of parameter estimation of time series data using discrete Fourier transform(DFT). DFT have been mainly used to precisely and rapidly obtain the frequency of a signal. In a dynamic system, a real part of a mode used to learn damping characteristics is a more important factor than the frequency of the mode. The parameter estimation method of this paper can directly estimate modes and parameters, indicating the characteristics of a dynamic system, on the basis of the Fourier transform of the time series data. Real part of a mode estimates by subtracting a frequency of the Fourier spectrum corresponding to 0.707 of a magnitude of the peak spectrum from a peak frequency, or subtracting a frequency of the power spectrum corresponding to 0.5 of the peak power spectrum from a peak frequency, or comparing the Fourier(power) spectrum ratio. Also, the residue and phase of time signal calculate by simple equation with the real part of the mode and the power spectrum that have been calculated. Accordingly, the proposed algorithm is advantageous in that it can estimate parameters of the system through a single DFT without repeatedly calculating a DFT, thus shortening the time required to estimate the parameters.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.1
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• pp.515-519
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• 2005

Pitch period that is a important factor in speech signal processing is used in various applications such as speech recognition, speaker identification, speech analysis and synthesis. So many pitch detection algoritms have been studied until now. AMDF which is one of pitch period detection algorithms chooses the time interval from valley point to valley point as pitch period. In selection of valley point to detect pitch period, complexity of the algoritm is increased. So in this paper we proposed the simple algorithm using modified AMDF that detects global minimum valley point as pitch period of speech signal and compared existing methods with it through simulation.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.6 no.1
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• pp.25-29
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• 2002

There is an increasing interest in high-speed signal processing in modern telecommunication and SC circuit, HDTV, ISDN. There are many methods of high-speed signal processing. This paper describes a design approach for the realization of high-frequency Op-amp in CMOS technology. A limiting factor in Op-amp based analog integrated circuits is the limited useful frequency range. this thesis will develop a CMOS op-amp architecture with improved gainband width product with this technique an op-amp will achieve up to 170MHz (CL=2pF) unity-gain frequency with a 1.2-micron design rule. This CMOS op-amp is particularly suitable for achieving wide and stable closed-loop band widths, such as required in high-frequency SC filters, high-speed analog circuits.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.8
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• pp.2879-2899
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• 2021

The tone reservation (TR) scheme is an attractive method to reduce peak-to-average power ratio (PAPR) in the filter bank multicarrier with offset quadrature amplitude modulation (FBMC-OQAM) systems. However, the high PAPR of FBMC signal will severely degrades system performance. To address this issue, a cyclic shift based TR (CS-TR) scheme with embedding side information (SI) is proposed to reduce the PAPR of FBMC signals. At the transmitter, four candidate signals are first generated based on cyclic shift of the output of inverse discrete Fourier transform (IDFT), and the SI of the selected signal with minimum peak power among the four candidate signals is embedded in sparse symbols with quadrature phase-shift keying constellation. Then, the TR weighted by optimal scaling factor is employed to further reduce PAPR of the selected signal. At the receiver, a reliable SI detector is presented by determining the phase rotation of SI embedding symbols, and the transmitted data blocks can be correctly demodulated according to the detected SI. Simulation results show that the proposed scheme significantly outperforms the existing TR schemes in both PAPR reduction and bit error rate (BER) performances. In addition, the proposed scheme with detected SI can achieve the same BER performance compared to the one with perfect SI.

• Korean Journal of Pharmacognosy
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• v.50 no.1
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• pp.18-24
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• 2019

Andrographolide, the main compound of Andrographis paniculata (A. paniculata), shows various biological properties including anti-viral, anti-inflammatory, anti-diabetic, and hepatoprotective effects. Our previous study has shown that A. paniculata extract exerts antiaging effects by activation of stemness in epidermal stem cells (EpSCs). In this study, we investigated the effect of andrographolide as a main compound of A. paniculata on EpSCs and its mechnism of action using several in vitro assays. Andrographolide increased the proliferation of EpSCs and induced cell cycle progression. Additionally, andrographolide increased VEGF production and the expression of stem cell markers integrin ${\beta}1$ and p63. Furthermore, phosphorylation levels of extracellular signal-regulated kinase 1/2 (ERK1/2), S6 ribosomal protein (S6RP) and Akt were increased by andrographolide. Taken together, these results indicate that andrographolide-induced proliferation of EpSCs is mediated by the ERK1/2, Akt-dependent pathway with increased production of VEGF and upregulated stemness through integrin ${\beta}1$ and p63.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.2
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• pp.325-328
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• 2020

This paper demonstrated a voltage-controlled oscillator (VCO) using cost-effective (1-poly 6-metal) mixed signal standard CMOS process. To have the high-quality factor inductor in LC resonator with thin metal thickness, patterned-ground shields (PGS) was adopted under the spiral to effectively reduce the ac current of low resistive Si substrate. And, because of thin top-metal compared with that of RF option (2 ㎛), we make electrically connect between the top metal (M6) and the next metal (M5) by great number of via array along the metal traces. The circuit operated from 2.48 GHz to 2.62 GHz tuned by accumulation-mode varactor device. And the measured phase noise of LC VCO has -123.7 dBc/Hz at 1MHz offset at 2.62 GHz and the dc-power consumption shows 2.07 mW with 1.8V supply voltage, respectively.