• Korean Circulation Journal
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• v.53 no.8
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• pp.499-518
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• 2023

Cardiovascular diseases (CVDs), including coronary artery disease, stroke, heart failure, and hypertension, are the global leading causes of death, accounting for more than 30% of deaths worldwide. Although the risk factors of CVDs have been well understood and various treatment and preventive measures have been established, the mortality rate and the financial burden of CVDs are expected to grow exponentially over time due to the changes in lifestyles and increasing life expectancies of the present generation. Recent advancements in metagenomics and metabolomics analysis have identified gut microbiome and its associated metabolites as potential risk factors for CVDs, suggesting the possibility of developing more effective novel therapeutic strategies against CVD. In addition, increasing evidence has demonstrated the alterations in the ratio of Firmicutes to Bacteroidetes and the imbalance of microbial-dependent metabolites, including short-chain fatty acids and trimethylamine N-oxide, play a crucial role in the pathogenesis of CVD. However, the exact mechanism of action remains undefined to this day. In this review, we focus on the compositional changes in the gut microbiome and its related metabolites in various CVDs. Moreover, the potential treatment and preventive strategies targeting the gut microbiome and its metabolites are discussed.

• Child Health Nursing Research
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• v.14 no.4
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• pp.396-404
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• 2008

Purpose: This study was conducted to identify the level of quality of family life, parental locus of control, and parental sense of competence, and to elucidate factors that influence family quality of life in the mothers of children with Attention Deficit/Hyperactive Disorder (ADHD). Method: A convenient sample of mothers from 6 child psychiatric clinics was used in this cross-sectional survey design. Questionnaires used for data collection included the following scales: Family Quality of Life, Parental Locus of Control-Short Form Revised, Parental Sense of Competence. Results: The level of family quality of life was mid-range. A positive relationship was found between Family Quality of Life and the research variables. The significant predictors of family quality of life were parental locus of control, parental sense of competence, and duration of medication and these variables accounted for 21.8% of the variance in family quality of life. Conclusions: These results indicate that family quality of life is an important factor which health care provider should assess and evaluate for children with ADHD and their families. The results of this study suggest that family quality of life is an important link with parental sense of competence and parental locus of control.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2009.04a
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• pp.344-349
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• 2009

To be Low Carbon and Green Growth, it is necessary that Long-Life Housing based on Green Technology is supplied. The main concern at the moment is developing Sustainable Housing relative to Life-Cycle or Life-Style of the residents, and the resident of Remodeling or Redevelopment. This study is aim to be Development of Maintenance Process in order to make steady dwelling when supplying Long-Life Housing that separates Support(Skeleton) and Infill different from the existing Short-Life Housing, and has durability, alterability, available remodeling, easy maintenance. Long-Life Housing should consider the maintenance about movement and variableness. In contrast, the maintenance of the existing Housing is regular maintenance, change and repair by damage. As well as Long-Life Housing should be demanded proper Development of Maintenance Process because of difference of Housing in concept, design and Construction. Therefore, this study looks into problems when applying Development of Maintenance Process in Long-Life Housing, and shows Development of Maintenance Process about the efficient Long-Life Housing for the manager.

• Reproductive and Developmental Biology
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• v.37 no.3
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• pp.161-167
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• 2013

The karyotype of Korean short-hair cat was presented using the G-, C- and NOR-banding techniques. For chromosomes preparation, the fetus skin fibroblast cells were cultured and metaphases were obtained. In results, the Korean short-hair cat had 38 chromosomes with XX or XY, which consisted of 5 pairs of metacentric chromosomes(Group A and C), 3 pairs of submetacentric chromosomes (Group B), 6 pairs of medium metacentric chromosomes except for 1 pair of medium submetacentric D2 chromosomes (Group D, E), 2 pairs of acrocentric chromosomes(Group F) and metacentric X and Y sex chromosomes. In G-banding analysis, the Korean short-hair cat exhibited a typical and identical G-banding pattern in each homologous chromosome. Total number of bands and landmarks on the G-banded chromosomes of Korean short-hair cat well correspond to those of international standardization of karyotype of domestic cat. The heterochromatins of Korean short-hair cat chromosomes distributed at terminal and/or centromere regions on almost chromosomes by C-banding analysis. In addition, the C-banding pattern showed greatly heteromorphic in some chromosomes. Using the AgNOR-staining, we found the nucleolar organizer regions(NORs) of Korean short-hair cat located at chromosomes 1p12 site in E group. The quantity and number of NORs were constant among cells.

• Research in Community and Public Health Nursing
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• v.14 no.2
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• pp.263-273
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• 2003

Objectives: The purpose of this study was to identify the family phenomenon and characteristics by ICNP such as family shape, life standard. area, and development stage. Method: 1. Sample size was 115. 2. Data analysis method included frequency analysis including ratio. Results: 1. On the distribution of the family phenomena by family shape, the nuclear family showed a higher ratio on the distribution in family communication and the unhealthy life style. The nuclear family was related to children andhad a higher ratio on the inadequate care management of the sick member. The extended family showed the highest ratio on the inadequate care management of sick member. 2. On the distribution of the family phenomena by family life standard, the family with medium life standard showed a higher ratio on the inappropriate family coping, whereas the family with lower life standard appeared to have a higher ratio on the inadequate care management of the sick member. 3. On the distribution of the family phenomena by area. the large city area showed the highest ratio on the inappropriate family coping, the medium and small city area appeared to have the highest ratio on the unhealthy life style. The county area showed the highest ratio on the inadequate care management of sick member. 4. On the distribution of the family phenomena by development stage, the family in rearing period showed a higher ratio on the inappropriate family coping and the lack of family intimacy. Families with preschool children showed a higher ratio on the unhealthy life style, and families with school age children showed the highest ratio on the inappropriate family coping. Families with adolescents appeared to have the highest ratio on the disturbance in family communication, and families with launching young adults showed the highest ratio on the inadequate care management of sick member. 5. On the distribution of the family characteristics by family shape, the nuclear family showed a higher ratio on the family characteristics such as less communication chances among family members and neglect of general child rearing, whereas the third generation family appeared to have a higher ratio on the characteristics such as overburden of housewife's role and short of caring among family members. 6. On the distribution of the family characteristics by family life standard, the family of medium life standard showed higher ratio on the family characteristics such as a few communication chance among family and overburden of housewife's role, and the family of lower life standard appeared to higher ratio on the family characteristics such as short of caring among family members. 7. On the distribution of the family characteristics by area. the large city area showed a higher ratio on the family characteristics such as overburden of housewife's role and neglect of general child rearing. The medium and small city area appeared to have a higher ratio on the family characteristics such as less communication chancec among family members. The county area showed a higher ratio on the family characteristics such as short-term care among family members. 8. On the distribution of the family characteristics by development stage, the family with rearing period showed a higher ratio on the family characteristics such as neglect of general child rearing. Families with preschool children showed a higher ratio on the family characteristics such as less communication chancec among family members. Families with school age children showed a higher ratio on the family characteristics such as overburden of housewife's role. Families with adolescents appeared to have a higher ratio on the family characteristics such as less communication chances among family members. Families with launching young adults showed a higher ratio on the family characteristics such as less communication chances and short-term care among family members.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.9
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• pp.1328-1336
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• 2004

According to our fatigue tests carried out at 20 Hz, R=0.1 on transversely butt-welded joints, fatigue strengths of as-welded specimens, that is, specimens having residual stress are higher than those of annealed specimens in short life range, but vice verse in long life range. This behavior seems to be concerned mainly with residual stress relaxation by applied loading. After analyzing the welding process, we conducted finite element analysis to quantify the degree of residual stress relaxation. By taking into account residual stress relaxation, modified Goodman diagram, and nominal stress, we evaluated the fatigue life of the welded joint from the S-N curve for the parent material. The estimated results are in a good agreement with the experimental results.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.108-113
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• 2004

According to our fatigue tests carried out at 20 Hz, R=0.1 on transversely butt~welded joints, fatigue strengths of as-welded specimens, that is, specimens having residual stress are higher than those of annealed specimens in short life range, but vice verse in long life range. This behavior seems to be concerned mainly with residual stress relaxation by applied loading. After analyzing the welding process, we conducted finite element analysis to quantify the degree of residual stress relaxation. By taking into account residual stress relaxation, modified Goodman diagram, and nominal stress, we evaluated the fatigue life of the welded joint from the S-N curve for the parent material. The estimated results are in a good agreement with the experimental results.

• Proceedings of the International Microelectronics And Packaging Society Conference
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• 2002.11a
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• pp.27-32
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• 2002

In this paper, global full 3D finite element analysis fatigue models are constructed for flip-chip BGA on board to predict the creep fatigue life of solder joints during the thermal cycling test. The fatigue model applied is based on Darveaux's empirical equation approach with non-linear viscoplastic analysis of solder joints. It was estimated by the creep life as the variations of the four kinds of thermal cycling test conditions, pad structure, composition and size of solder ball. The shortest fatigue life of results was obtained at the thermal cycling testing condition of -65℃ ∼ 150℃. It was increased about 3.5 times in comparison with that of 0℃ ∼ 100℃. As the change of pad structure at the same other conditions, the fatigue life of SMD structure increased about 5.7% as compared with NSMD structure. Consequently, it was confirmed that the fatigue life became short as the creep strain energy density increased in solder joint.

• The Korean Journal of Mycology
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• v.46 no.1
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• pp.28-33
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• 2018

A fungal isolate designated KNU16-033 was isolated from a soil sample in Daegu, Korea. White, short, and felt-like aerial mycelia appeared on the surface of colonies of the isolate. Colonies with a smooth texture developed slowly and reached a diameter of 78 mm after 21 days of incubation on potato dextrose agar. This isolate displayed globose, colorless or light yellow sporangiospores, which differed morphologically from the sporangiospores of Gongronella butleri, which were hyaline, oval to flattened on one side or almost reniform. Based on these morphological characteristics and phylogenetic analysis using internal transcribed spacer regions, the isolated fungus was identified as G. guangdongensis belonging to Cunninghamellaceae. To our knowledge, this is the first record of G. guangdongensis in Korea.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2000.05a
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• pp.46-49
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• 2000

This paper studied development of the program for estimation the life time of insullating materials and the longtime breakdown voltage. First, short-time breakdown voltage of Epoxy and insulating oil was measured. Life exponent was gained from measurement of insulating breakdown time of the specimens. Life time is presumed from program. The estimation program is based on the "Inverse Power Law", defined $V^nt$ is constant. After gaining the life exponent n, it is mapping the longtime breakdown voltages. On the base of life exponent, the estimation the lifetime and usefulness of the insulation systems are possible, furthermore easy calculation is possible.