• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.11
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• pp.1221-1229
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• 2014

This paper proposes an approach for predicting the fatigue life of a propeller shaft of a forklift truck by an accelerated life test method. The accelerated life test method adopted in this study is the calibrated accelerated life test, which is highly effective in the prediction of the lifetime and enables significant reduction of the test time as well as a quantification of reliability in the case of small sample sizes. First, the fatigue test was performed under two high stress levels, and then, it was performed by setting low stress levels in consideration of the available test time and extrapolation. Major reliability parameters such as the lifetime, accelerated power index, and shape parameter were obtained experimentally, and the experimentally predicted lifetime of the propeller shaft was verified through comparison with results of an analysis of load spectrum data under actual operating conditions.

• Explosives and Blasting
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• v.36 no.3
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• pp.10-18
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• 2018

The dynamic behaviour of the rock mass under the dynamic load is different from the static application of the maximum load of the same size. An experimental approach to investigating rock behavior under dynamic loads is more difficult than that under static conditions in control of dynamic loads, measurement and analysis of the results. Numerical methods are less constrained by performing the experiments numerically, rather than experimental ones, so they can be very powerful analytical tool at the design stage. However, even if the algorithms of the analysis method are appropriate, careful analysis is required because the calculation results may vary largely depending on input data and boundary conditions. In this paper, when investigating the behavior of rock structures under dynamic load numerically, the effects of boundary conditions, dynamic load and calculation time step, and dynamic load characteristics on the calculation results were reviewed to provide guidance on setting up boundary conditions and calculation time step related to dynamic analysis.

• The Journal of Engineering Geology
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• v.27 no.1
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• pp.31-40
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• 2017

The slope stability analysis by the limit equilibrium method has the disadvantage that it can be applied only when the analysis is performed by setting the critical plane after analyzing the active surface many times and the soil is uniform and only the safety factor can be calculated. However, the analysis using the strength reduction analysis method has advantages that the engineer can judge various aspects and calculate the safety factor. In this study, the safety factor according to the change of slope and shear strength was compared and analyzed using limit equilibrium analysis and strength reduction method. It is suggested that it is desirable to use the strength reduction method which can synthetically review the stress, displacement, and strain in the soil.

• Korean Journal of Applied Biomechanics
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• v.15 no.2
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• pp.83-92
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• 2005

Computer-assisted motional analysis is a popular method in biomechanical studies. Validation of the specific system and its measurement are fundamental to its application in the areas. Because the accuracy and consistency of a particular system provide the researchers with critical information to assist in making judgements regarding the degree to which inferences can be drawn from measurement data. The purpose of this study was to assess the accuracy and consistency of the Kwon3D motion analysis system. Validation parameters were five lengths from eight landmarkers in combination with the DLT reconstruction error values, digitizing monitor resolutions, and numbers of control points. With the best setting, Kwon3D's estimations of 260cm, 200cm, 140cm, 100cm, and 20cm were $260.33{\pm}.688cm$, $199.98{\pm}.625cm$, $139.89{\pm}.537cm$, $99.75{\pm}.466cm$, $20.08{\pm}.114$, respectively. There was no significant DLT error value difference between two monitor resolutions, but 0.27cm significant difference in 260cm estimation. There were significant differences in 260cm and 200cm estimations between with 33-control-point DLT error and with 17-control-point DLT error, but no in 140cm, 100cm, and 20cm estimations. Test-retest results showed that Kwon3D measurements were highly consistent with reliability coefficients alpha of .9263 and above.

• Water for future
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• v.15 no.3
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• pp.37-47
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• 1982

In the past, the design flow of the urban storm drainage systems has been used largely on a basis of empirical and experience, and the rational formula one of empirical method has been widely used for our country, as well as world wide. But the empirical method has insufficient factor because minimal consideration is given to the relationship of the parameters in the equation to the processes being considered, and considerable use of experience and judgment in setting values to the coefficients in the equation is made. The postcomputer era of hydrology has brought an acceleration development of mathematical methods, thus mathematical models are methods which will greatly increase our understanding in hydrology. On this study, a simple mathematical model of urban presented by British Road Research Laboratory is tested on urban watersheds in Ju An Ju Gong Apartment. The basin is located in Kan Seog Dong, Inchon. The model produces a runoff hydrograph by applying rain all to only the directly connected impervious area of the basin. To apply this model the basin is divided into contributing areas or subbasins. With this information the time area for contributing is derived. The rainfall hyetograph to design storm for the basin flow has been obtained by determination of total rainfall and the temporal distribution of that rainfall determined on the basis of Huff's method form historical rainfall data of the basin. The inflows from several subbaisns are successively routed down the network of reaches from the upstream end to the outlet. A simple storage routing technique is used which involves the use of the Manning equation to compute the stage discharge curve for the cross-section in question. To apply the model to a basin, the pattern of impervious areas must be known in detail, as well as the slopes and sizes of all surface and subsurface drains.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.09a
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• pp.553-558
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• 2010

The behavior of composite piles composed of steel pipe pile in the upper part and concrete pile in the lower part by a mechanical splicing joint was examined by field lateral load tests and bending tests. A total of 7 piles including two instrumented piles for bending test were installed. The soil profile consists of soft clay with weak silt with shallow groundwater level. Laboratory tests were carried out to determine the basic soil characteristics and the strength parameters. This paper presents the composite pile behavior with various portions of the upper steel pile: 0, 20, 30, and 45% of the pile embedded pile length. Three-point bending tests were performed to investigate the stress-strain relation at the mechanical joint. Based on these test results, the behavior of composite piles with various upper steel pile length are evaluated and the stability of mechanical joints are examined. Through comparisons with results of field load tests, it was found that lateral load carrying capacity of the composite piles increased and deflections of the composite piles decreased with increasing the upper steel piles. The mechanical joint was proved to retain its structural stability against the tested load conditions. Economical benefits of composite pile of this kind can be gained by setting adequately the length of the upper steel pipe piles.

• Nutrition Research and Practice
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• v.8 no.5
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• pp.571-579
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• 2014

BACKGROUND/OBJECTIVES: The objectives were to investigate the effect of a 12-wk intervention with behavioral modification on clinical characteristics and dietary intakes of young and otherwise healthy obese and to identify factors for successful weight loss. The goal was to lose 0.5 kg per week by reducing 300-500 kcal/day and by increasing physical activities. SUBJECTS AND METHODS: Forty four obese subjects (BMI > 25) and 19 normal weight subjects (BMI 18.5-23) finished the 12-week intervention. Obese subjects participated in 5 group educations and 6 individual counseling sessions. Normal weight subjects attended 6 individual counseling sessions for evaluations of dietary intake and exercise pattern. Anthropometric and clinical characteristics and 3-day dietary records were evaluated at baseline and week12. RESULTS: Weight and serum triglyceride and free fatty acid concentrations in obese group decreased significantly with intervention. Intakes of energy, fat, and cholesterol decreased significantly in the obese. Active participation, realistic weight loss goal setting, and weight gain after high school graduation not during childhood were identified as key factors for successful weight loss. CONCLUSIONS: The 12-week intervention with behavioral modification resulted in reduced energy and fat intakes and led to significant weight loss and improvements of clinical characteristics in the obese. The finding that those who became obese during childhood lost less weight indicates the importance of 'early' intervention.

• Biomolecules & Therapeutics
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• v.11 no.3
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• pp.178-182
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• 2003

The clinical use of once daily aminoglycoside (ODA) dosing has been increased because of the potential therapeutic advantages of this dosing regimen. To evaluate the optimal sampling times of ODA dosing method in a clinical setting, the study was prospectively conducted in a total of 28 patients with UTI. All of the patients were intravenously administered gentamicin at a dose of 7 mg/kg over 60 minutes and randomly divided into two groups. Blood was collected at 0, 2, and 6 hours in Group A and at 1, 2, and 6 hours in Group B after the end of 1-hour infusion. The pharmacokinetic parameters (Ke, Vd and Cmax) obtained using the 0, 6 hour levels and 2, 6 hour levels in Group A were statistically different while those of 1, 6 hour levels and 2, 6 hour levels in Group B were similar. This finding indicated that the distributional phase of ODA is completed within 1 hour following the end of the I-hour infusion. If we are allowed to collect only two blood samples in ODA considering patients comfort and the analytical cost of drug, the first one should be drawn after 1 hour following the end of infusion to obtain adequate pharmacokinetic information.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2006.05a
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• pp.187-192
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• 2006

In the absence of a clear command and control structure, a key challenge in supply chain management is the coordination and alignment of the supply chain members who pursue divergent and often conflicting goals. The newsvendor model is typically used as a framework to quantify the cost of misalignment and to assess the impact of coordination initiatives. This paper considers a fuzzy approach for the newsvendor problem which includes a single manufacturer and a single retailer. We use several fuzzy parameters in the model such as the demand, the wholesale price, and the market sales price. We apply a coordination policy, referred to as buyback, to solve the fuzzy newsvendor problem. Based on the buyback policy, the optimal order quantity of the retailer can be computed, and the possible profits of the members in the supply chain can be calculated with minimum sharing of private information. Focusing on the fuzzy model with buyback policy for the newsvendor problem, we illustrate exemplary fuzzy models. We also illustrate an integration model, which extends a single-manufacturer-single-retailer model to the single-manufacturer-multiple-retailer setting. In the extended model, we consider three coordination policies including quantity discount, profit sharing, and buyback, as well as non-coordination case.

• Journal of Pharmaceutical Investigation
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• v.37 no.2
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• pp.107-111
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• 2007

Epigallocatechin gallate (EGCC), a flavonoid, is the main component of green tea extracts. EGCG has been reported to be an inhibitor of P-glycoprotein (P-gp) and cytochrom P450 3A(CYP3A4). This study investigated the effect of long-term administration of EGCG on the pharmacokinetics of verapamil in rats. Pharmacokinetic parameters of verapamil were determined after oral administration of verapamil (9 mg/kg) in rats pretreated with EGCG (7.5 mg/hg) for 3 and 9 days. Compared to oral control group, the presence of EGCG significantly (p<0.01) increased the area under the plasma concentration-time curve (AUC) of verapamil by 102% (coad), 83.2% (3 days) and 52.3% (9 days), and the peak concentration $(C_{max})$ by 134% (coad), 120% (3 days) and 66.1% (9 days). The absolute bioavailability (A.B.%) of verapamil was significantly (p<0.01) higher by 8.4% (coad), 7.7% (3 days), 6.4% (9 days) compared to control (4.2%), and presence of EGCG was no significant change in the terminal half-life $(t_{1/2})$ and the time to reach the peak concentration $(T_{max})$ of verapamil. Our results indicate that EGCG significantly enhanced oral bioavailability of verapamil in rats, implying that presence of EGCG could be effective to inhibit the CYP3A4-mediated metabolism and P-gp efflux of verapamil in the intestine. Drug interactions should be considered in the clinical setting when verapamil is coadministrated with EGCG or EGCG-containing dietary.