• The Korean Journal of Physiology and Pharmacology
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• 제18권3호
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• pp.201-209
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• 2014

The present study was designed to investigate the efficacy of selective $ET_A$ receptor antagonist, ambrisentan on hyperhomocysteinemia-induced experimental vascular dementia. L-methionine was administered for 8 weeks to induce hyperhomocysteinemia and associated vascular dementia in male rats. Ambrisentan was administered to L-methionine-treated effect rats for 4 weeks (starting from $5^{th}$ to $8^{th}$ week of L-methionine treatment). On $52^{nd}$ day onward, the animals were exposed to the Morris water maze (MWM) for testing their learning and memory abilities. Vascular endothelial function, serum nitrite/nitrate levels, brain thiobarbituric acid reactive species (TBARS), brain reduced glutathione (GSH) levels, and brain acetylcholinesterase (AChE) activity were also measured. L-methionine-treated animals showed significant learning and memory impairment, endothelial dysfunction, decrease in/serum nitrite/nitrate and brain GSH levels along with an increase in brain TBARS levels and AChE activity. Ambrisentan significantly improved hyperhomocysteinemia-induced impairment of learning, memory, endothelial dysfunction, and changes in various biochemical parameters. These effects were comparable to that of donepezil serving as positive control. It is concluded that ambrisentan, a selective $ET_A$ receptor antagonist may be considered as a potential pharmacological agent for the management of hyperhomocysteinemia-induced vascular dementia.

• 디지털융복합연구
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• 제11권10호
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• pp.453-458
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• 2013

HMM 음성 인식 시스템은 환경적 잡음과 여러 음성의 혼합으로 인하여 정확한 음성을 인지하지 못하는 단점이 있다. 따라서 본 논문은 잡음 음성으로 부터 원하는 음성만 선택하여 추출하기 위한 음성 특징 추출 기법을 CHMM을 이용하여 제안한다. 선택적 음성 추출을 위한 채널 유사성 상관 관계를 이용하여 음성 특징을 추출하는 방법을 사용하였다. 제안 기법의 실험 평가한 결과 평균 분리 왜곡도가 0.430dB 감소됨을 보임으로써 제안한 방법의 우수성을 확인하였다.

• 한국국방경영분석학회지
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• 제3권2호
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• pp.79-89
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• 1977

The purpose of this thesis is to overcome the shortcomings of the existing system which lacks cost-conciousness and does not consider the essentiality or the importance of an item, and to seek the method of providing effective, efficient and economic supply which is the objective of the military inventory management. Selective management technique and lot size model whose demand, and order and shipping time are distributed, are intorduced, and required distributions and parameters are analyzed. Finally hypothetical data are utilized to obtain the model output, which are compared with the existing model and analyzed.

• Journal of applied mathematics & informatics
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• 제13권1_2호
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• pp.301-322
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• 2003

The paper considers two mutually independent pests in presence of their common predator and discusses their control biologically by release of additional predators and chemically by using non-selective non-residual pesticide. It also verifies the results by special choice of parameters.

• 한국물환경학회지
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• 제23권5호
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• pp.591-599
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• 2007

The quality of water released from a stratified reservoir is dependent on various factors such as the location and shape of intake facility, structure of reservoir stratification, profile of water quality constituent, and withdrawal flux. Sometimes, selective withdrawal capabilities can provide the operational flexibility to meet the water quality demands both in-reservoir and downstream. The objective of this study was to evaluate the performance of a one-dimensional reservoir selective withdrawal model (SELECT) as a tool for supporting downstream water quality management for Daecheong and Imha reservoirs. The simulated water quality variables including water temperature, dissolved oxygen (DO), conductivity, turbidity were compared with the field data measured in tailwater. The model showed fairly satisfactory results and high reliability in simulating observations. The coefficients of determinant between simulated and observed turbidity values were 0.93 and 0.95 for Daecheong and Imha reservoirs, respectively. The outflow water quality was significantly influenced by water intake level under fully stratified condition, while the effect of intake amount was minor. In conclusion, the SELECT is simple but effective tool for supporting downstream water quality prediction and management for both reservoirs.

• 한국물환경학회지
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• 제27권6호
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• pp.743-753
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• 2011

One of the most important water management issues of Soyang Reservoir, located in North Han River in Korea, is a long term discharge of turbid water to downstream during flood season. Installation of a selective withdrawal structure (SWS) is planned by the reservoir management institute as a control measure of outflow water quality and associated negative impacts on downstream water use and ecosystem. The objective of the study was to explore the effectiveness of the SWS on the control of outflow turbidity under two different hydrological years; one for normal flood year and another for extreme flood year. A two-dimensional (2D), laterally averaged hydrodynamic and water quality model (CE-QUAL-W2) was set up and calibrated for the reservoir and used to evaluate the performance of the proposed SWS. The results revealed that the SWS can be an effective method when the ${\Theta}$ value, the ratio between the amount of turbid water that containing suspended sediment (SS) greater than 25 mg/L and the total storage of the reservoir, is 0.59 during the normal flood year. However, the effectiveness of the SWS could be marginal or negative in the extreme flood year when ${\Theta}$ was 0.83. The results imply that the SWS is an effective alternative for the control of turbid water for moderate flood events, but not a sufficient measure for large flood events that are expected to happen more often in the future because of climate change.

• 정보관리학회지
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• 제2권2호
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• pp.150-169
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• 1985

오늘날 정보검색(情報檢索)시스팀의 대표적(代表的)인 한 유형(類型)으로서 널리 보급(普及)되어 운영(運營)되고 있는 SDI(Selective Dissemination of Information)시스팀에 관(關)하여 기술(記述)하였다. 이것은 컴퓨터기술(技術)의 정보검색(情報檢索)에의 응용(應用)으로서 이용자(利用者)의 요구주제(要求主題)에 부합(符合)되는 문헌(文獻)을 검색(檢索)하기 위하여 색인어(索引語)와 일치(一致)(match) 되는 문헌(文獻)을 탐색(探索)하는데 이용(利用)되는 시스팀을 설명(說明)하기 위해 자주 쓰여지는 용어(用語)이다. SDI시스팀을 개발(開發)한 "Luhn"이 최초(最初)로 그 개념(槪念)을 발표(發表)한 이래(以來) 지금까지 개발(開發)되어온 각종(各種)의 SDI시스팀들을 조사(調査) 비교(比較)하고, 이 시스팀들의 발전단계(發展段階), 구성(構成) 및 특성(特性)과 시스팀 설계(設計)에 관(關)한 제문제점등(諸問題點等)에 대(對)해서도 분석(分析) 조사(調査)하였다.

• 한국건설관리학회:학술대회논문집
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• 한국건설관리학회 2004년도 제5회 정기학술발표대회 논문집
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• pp.437-441
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• 2004

선진국에서는 건설분쟁을 소송 외 분쟁해결방법(ADR)에 의한 해결이 보편화 되어 있다. 최근 우리나라에서도 공공건설공사에서의 계약상대자간의 클레임이 증가하는 추세이다. 그러나 현행 공공공사 도급계약의 분쟁해결 조항은 분쟁 해결절차가 명시되지 않아 적시의 클레임 제기에 어려움이 있고, 소송과 중재를 동시에 규정한 선택적 중재조항으로 되어있어 중재에 의한 분쟁해결의 걸림돌이 되고 있다. 이에 국내외의 분쟁해결제도 및 절차를 검토하고 판례를 연구하여 선택적 중재조항에 대한 해설방법을 고찰하여 공사계약일반조건 분쟁해결조항의 개선방안을 제시하고자 한다.

• The Korean Journal of Pain
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• 제19권2호
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• pp.249-252
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• 2006

Postlaminectomy syndrome is characterized by persistent low back pain and radiculopathy of the legs after surgery of the spine. Pseudomeningocele is an uncommon cause of postlaminectomy syndrome; it is characterized by an extradural collection of cerebrospinal fluid (CSF) without dural covering, resulting from unrecognized dural tears at the time of lumbar surgery. In most cases, surgery to repair a pseudomeningocele is recommended. However if surgical treatment does not yield symptomatic relief, then conservative treatment should be considered. We treated a patient with a pseudomeningocele after spine surgery in which selective transforaminal epidural block produced long-term relief of symptoms. Here we describe the management of this patient.

• 정보관리학회지
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• 제1권1호
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• pp.146-161
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• 1984

오늘날 정보검색(情報檢索)시스팀의 대표적(代表的)인 한 유형(類型)으로서 널리 보급(普及)되어 운영(運營)되고 있는 SDI(Selective Dissemination of Information)시스팀에 관(關)하여 기술(記述)하였다. 이것은 컴퓨터기술(技術)의 정보검색(情報檢索)에의 응용(應用)으로서 이용자(利用者)의 요구(要求) 주제(主題) 부합(符合)되는 문헌(文獻)을 검색(檢索)하기 위하여 색인어(索引語)와 일치(一致)(match)되는 문헌(文獻)을 탐색(探索)하는데 이용(利用)되는 시스팀을 설명(說明)하기 위해 자주 쓰여지는 용어(用語)이다. SDI시스팀을 개발(開發)한 "Luhn"이 최초(最初)로 그 개념(槪念)을 발표(發表)한 이래(以來) 지금까지 개발(開發)되어온 각종(各種)의 SDI시스팀들을 조사(調査) 비교(比較)하고, 이 시스팀들의 발전단계(發展段階), 구성(構成) 및 특성(特性)과 시스팀설계(設計)에 관(關)한 제문제점등(諸問提點等)에 대(對)해서도 분석(分析) 조사(調査)하였다.