• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.201-209
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• 2014

The present study was designed to investigate the efficacy of selective $ET_A$ receptor antagonist, ambrisentan on hyperhomocysteinemia-induced experimental vascular dementia. L-methionine was administered for 8 weeks to induce hyperhomocysteinemia and associated vascular dementia in male rats. Ambrisentan was administered to L-methionine-treated effect rats for 4 weeks (starting from $5^{th}$ to $8^{th}$ week of L-methionine treatment). On $52^{nd}$ day onward, the animals were exposed to the Morris water maze (MWM) for testing their learning and memory abilities. Vascular endothelial function, serum nitrite/nitrate levels, brain thiobarbituric acid reactive species (TBARS), brain reduced glutathione (GSH) levels, and brain acetylcholinesterase (AChE) activity were also measured. L-methionine-treated animals showed significant learning and memory impairment, endothelial dysfunction, decrease in/serum nitrite/nitrate and brain GSH levels along with an increase in brain TBARS levels and AChE activity. Ambrisentan significantly improved hyperhomocysteinemia-induced impairment of learning, memory, endothelial dysfunction, and changes in various biochemical parameters. These effects were comparable to that of donepezil serving as positive control. It is concluded that ambrisentan, a selective $ET_A$ receptor antagonist may be considered as a potential pharmacological agent for the management of hyperhomocysteinemia-induced vascular dementia.

• Journal of Digital Convergence
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• v.11 no.10
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• pp.453-458
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• 2013

HMM Speech recognition systems have a few weaknesses, including failure to recognize speech due to the mixing of environment noise other voices. In this paper, we propose a speech feature extraction methode using CHMM for extracting selected target voice from mixture of voices and noises. we make use of channel similarity and correlate relation for the selective speech extraction composes. This proposed method was validated by showing that the average distortion of separation of the technique decreased by 0.430 dB. It was shown that the performance of the selective feature extraction is better than another system.

• Journal of the military operations research society of Korea
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• v.3 no.2
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• pp.79-89
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• 1977

The purpose of this thesis is to overcome the shortcomings of the existing system which lacks cost-conciousness and does not consider the essentiality or the importance of an item, and to seek the method of providing effective, efficient and economic supply which is the objective of the military inventory management. Selective management technique and lot size model whose demand, and order and shipping time are distributed, are intorduced, and required distributions and parameters are analyzed. Finally hypothetical data are utilized to obtain the model output, which are compared with the existing model and analyzed.

• Journal of applied mathematics & informatics
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• v.13 no.1_2
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• pp.301-322
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• 2003

The paper considers two mutually independent pests in presence of their common predator and discusses their control biologically by release of additional predators and chemically by using non-selective non-residual pesticide. It also verifies the results by special choice of parameters.

• Journal of Korean Society on Water Environment
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• v.23 no.5
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• pp.591-599
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• 2007

The quality of water released from a stratified reservoir is dependent on various factors such as the location and shape of intake facility, structure of reservoir stratification, profile of water quality constituent, and withdrawal flux. Sometimes, selective withdrawal capabilities can provide the operational flexibility to meet the water quality demands both in-reservoir and downstream. The objective of this study was to evaluate the performance of a one-dimensional reservoir selective withdrawal model (SELECT) as a tool for supporting downstream water quality management for Daecheong and Imha reservoirs. The simulated water quality variables including water temperature, dissolved oxygen (DO), conductivity, turbidity were compared with the field data measured in tailwater. The model showed fairly satisfactory results and high reliability in simulating observations. The coefficients of determinant between simulated and observed turbidity values were 0.93 and 0.95 for Daecheong and Imha reservoirs, respectively. The outflow water quality was significantly influenced by water intake level under fully stratified condition, while the effect of intake amount was minor. In conclusion, the SELECT is simple but effective tool for supporting downstream water quality prediction and management for both reservoirs.

• Journal of Korean Society on Water Environment
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• v.27 no.6
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• pp.743-753
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• 2011

One of the most important water management issues of Soyang Reservoir, located in North Han River in Korea, is a long term discharge of turbid water to downstream during flood season. Installation of a selective withdrawal structure (SWS) is planned by the reservoir management institute as a control measure of outflow water quality and associated negative impacts on downstream water use and ecosystem. The objective of the study was to explore the effectiveness of the SWS on the control of outflow turbidity under two different hydrological years; one for normal flood year and another for extreme flood year. A two-dimensional (2D), laterally averaged hydrodynamic and water quality model (CE-QUAL-W2) was set up and calibrated for the reservoir and used to evaluate the performance of the proposed SWS. The results revealed that the SWS can be an effective method when the ${\Theta}$ value, the ratio between the amount of turbid water that containing suspended sediment (SS) greater than 25 mg/L and the total storage of the reservoir, is 0.59 during the normal flood year. However, the effectiveness of the SWS could be marginal or negative in the extreme flood year when ${\Theta}$ was 0.83. The results imply that the SWS is an effective alternative for the control of turbid water for moderate flood events, but not a sufficient measure for large flood events that are expected to happen more often in the future because of climate change.

• Journal of the Korean Society for information Management
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• v.2 no.2
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• pp.150-169
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• 1985

This study is to introduce the SDI(Selective Dissemination of Information) system, a typical aspect of information retrieval systems nowadays quite popular. The term "SDI" is most often used to describe systems of using electronic data processing equipment as a means of matching the terms of user-interest profile against document descriptors and selecting those documents with a specified degree of similarity to the terms of the user-interest profile. Various up-ta-date informations on SDI systems developed after the first introduction of the original idea by "Luhn" are reviewed and compared. The stage of development, structure, characteristics, and various other matters concerning the SDI systems are analyzed, and discussed.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.437-441
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• 2004

This study aims to propose a set of improvement devices for construction dispute resolution clause of public improvement project in Korea. To do so, the study addresses the system and procedure of construction dispute resolution in domestic and overseas, and reviews precedent cases, specifically focused of a selective arbitration case. In public sector's initiated contracts, the absence of c)aim procedure clause is unable to response to the claims in timely manner, and the ambiguity of clause o( selective arbitration make it difficult to resolve a dispute by arbitration. Thus, in this study alternative dispute resolutions are explored as a way to resolve various construction disputes of public-initiated project in developed countries.

• The Korean Journal of Pain
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• v.19 no.2
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• pp.249-252
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• 2006

Postlaminectomy syndrome is characterized by persistent low back pain and radiculopathy of the legs after surgery of the spine. Pseudomeningocele is an uncommon cause of postlaminectomy syndrome; it is characterized by an extradural collection of cerebrospinal fluid (CSF) without dural covering, resulting from unrecognized dural tears at the time of lumbar surgery. In most cases, surgery to repair a pseudomeningocele is recommended. However if surgical treatment does not yield symptomatic relief, then conservative treatment should be considered. We treated a patient with a pseudomeningocele after spine surgery in which selective transforaminal epidural block produced long-term relief of symptoms. Here we describe the management of this patient.

• Journal of the Korean Society for information Management
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• v.1 no.1
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• pp.146-161
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• 1984

This study is to introduce the SDI(Selective Dissemination of Information) system, a typical aspect of information retrieval systems nowadays quite popular. The term "SDI" is most often used to describe systems of using electronic data processing equipment as a means of matching the terms of user-interest profile against document descriptors and selecting those documents with a specified degree of similarity to the terms of the user-interest profile. Various up-to-date informations on SDI systems developed after the first introduction of the original idea by "Luhn" are reviewed and compared. The stage of development, structure, characteristics, and various other matters concerning the SDI systems are analyzed and discussed.