The expression of phase II detoxifying enzymes is affected by a variety of compounds and the induction of the enzymes plays an essential role in chemoprevention. A variety of phytochemicals such as sulfur-containing chemoprotective agents (SCC) may trigger cellular signals and activate phase II gene expression through ARE activation. see induces glutathione S-transferases. Studies were conducted to investigate the role of mitogen-activated protein (MAP) kinase and phosphatidylinositol 3-kinase (PI3-kinase) in the induction of GST (e.g. rGSTA2) by sec. We also studied the MAP kinase pathway responsible for the GST expression by see and compared that with the pathway activated by oxidative stress as a result of sulfur amino acids deprivation (SAAD). see inhibited phosphorylation of ERK1/2 although the effect of see on JNK and p38 MAP kinase was minimal. Wortmannin and LY294002. PI3-kinase inhibitors. abolished the increases in rGSTA2 mRNA and protein levels by SCC. Deprivation of cystine and methionine caused oxidative stress in H4IIE cells. as evidenced by a decrease in the reduced glutathione and an increase in prooxidant production. Electrophoretic mobility shift assay revealed that the ARE complex consisting of Nrf-1/2 and Maf proteins was activated 12~48 h. The rGSTA2 mRNA and protein levels were increased by SAAD. Activation of ARE and induction of rGSTA2 were both completely inhibited by PI3-kinase inhibitors. Inhibition of p38 MAP kinase by SB203580 prevented the ARE-mediated rGSTA2 induction. The results of this study showed that PI3-kinase might play an essential role in the ARE-mediated rGSTA2 induction by see or SAAD and that the dual MAP kinase pathways were responsible for the enzyme induction.
The purpose of this study was to compare the differences in recognition of sexy body parts and apparel designs by age and to discover the correlations between sexy body parts and apparel designs. Data were collected through a survey of 265 males and 303 females. Analyses included t-tests, f-tests, and Pearson's correlations. The results were as followings; 1. The 20's-30's age group found female body parts were sexier than 40's-50's did. 20's-30's believed the male body was sexier than 40's-50's did. 2. The age groups found men's clothing designs were different by different age groups. Also, differences in female clothing designs were recognized by different age groups. 3. The 40's-50's age group recognized see-through sexier than 20's-30s did. Differences in sexy color recognition by age were also found. 4. There were correlations between most of sexy body parts and designs which emphasized the body parts. The results of this study show the differences in recognition and correlation by age. The results may be applied to developing sexy designs for different targeted age groups.
Journal of the Korean Society of Clothing and Textiles
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v.29
no.9_10
s.146
/
pp.1316-1328
/
2005
The purpose of this study was to compare the differences in recognition of sexy body parts and apparel designs by gender and correlations between sexy body parts and apparel designs. Data were collected through a survey of 265 males and 303 females. Data were analyzed by included t-tests, f-tests, and Pearson's correlations. The results were as follows: 1. Females found male body parts were sexier than males did. Males found female body parts were sexier than females did. 2. Females found men's clothing designs were sexier than males did. Also, males recognized women's clothing designs as sexier than females did. 3. Males found see-through and body-consciousness, the methods of designing sexy styles, were sexier than females did. Differences in sexy color recognition by gender were also found. 4. There were correlations between most of sexy body parts and designs which emphasized that body parts. The results of this study shows the differences in recognition and correlation by gender. The results may be applied to develope sexy designs for different genders.
Purpose: The purpose of this study was to explain the role transition process to nurse case managers (NCMs) for Medical-aid beneficiaries in Korea. Methods: Fourteen NCMs were interviewed regarding their experiences of becoming proficient in the new role of case manger. Data were analyzed through the application of grounded theory. Results: 'Taking root in a barren land' was the core category explaining the role transition process of NCMs. They engaged in four stages: launching, trial and error, proficiency, and wait-and-see stages. NCMs showed not only fear but also passion for case management practice. Despite their passion and effort, NCMs went through a period of trial and error. After becoming skilled, NCMs went through a stage of wait-and-see often because of job insecurity related to temporary position or few opportunities for promotion. Factors influencing NCMs' role transition process included their understanding of client characteristics, belief in case management, and support from their colleagues and families. Conclusion: NCMs experience many challenges in the process of becoming proficient NCMs. To help with their role transition, there is a need for education programs, preceptorship programs, research on their roles and functions, and regulation for securing NCMs' employment and career stability.
This study intends to analyze T-shirt designs, particularly in connection with pop art. 444 pieces of T-shirts which conveyed the pop art spirits of well-known designers were selected for five years from 2001 to 2005, through fashion magazines(Collection: Dong-ah TV, Collezioni: Italy). The findings are as follows. As for formative characteristics of pop art in T-shirts, previous studies were analyzed to set classifications criteria such as popularization of images, eroticism, lettering and graffiti, assemblage. The design factor of the image popularization includes everyday images, cartoon, celebrities, and caricature. Everyday images ranked first followed by cartoon, caricature and celebrities. The design factor of eroticism ranges from the see-through look, partial exposure of human body, symbolization of underwear, and to printing of sexy images. The see-through look was ranked first, followed by partial exposure of human body, symbolization of underwear, and printing of sexy images. The design factor of lettering and graffiti encompasses letters, numbers, symbols and logos. Adoption of letters, numbers or symbols was ranked first, followed by brand logos and graffiti. The design factor of Assemblage is closely related to a three-dimensional effect. Varied expressions are possible: combination of two different textiles and fusion of textile and non-textile. Combination of two different textiles are higher than fusion of textile and non-textile.
The purpose of this study is to present direction in outdoors space planning and design after direction through user characteristic analysis through spectacle component establishment of culture art center outdoors space through on-the-site analysis and literature investigation to culture art center of Seoul city and capital region 17 places in this research. The data was collected from classification and bisection kind, subdivision kind, and great classification composed to 17 items. User satisfaction side and Variable that is looked below satisfaction than average appeared to bench, pergola, sculpture facilities, pavement facilities, border facilities. And these facilities were analyzed dissatisfaction. When see satisfaction model, when make up culture art center or similar facilities in local government hereafter because parking facilities and rest area cause big effect in satisfaction, is judged that is item to consider most preferentially. In most case, parking lot security from outdoors space, resting place security, security of field performance facilities etc. taking a serious view because tendency that users see performance or use most vehicles except neighborhood walking area for a rest, a walk etc.. is trend. But, is judged that physical side so that can feel satisfaction as space security of quantitative side is important but users utilize substantially and side that is the program are more important in hereafter.
The causes of climate change are natural and artificial. Natural causes include changes in temperature and sunspot activities caused by changes in solar radiation due to large-scale volcanic activities, while artificial causes include increased greenhouse gas concentrations and land use changes. Studies have shown that excessive carbon use among artificial causes has accelerated global warming. Climate change is rapidly under way because of this. Due to climate change, the frequency and cycle of infectious disease viruses are greater and faster than before. Currently, the world is suffering greatly from coronavirus infection-19 (COVID-19). Korea is no exception. The first confirmed case occurred on January 20, 2020, and the number of infected people has steadily increased due to several waves since then, and many confirmed cases are occurring in 2021. In this study, we conduct a study on climate change before and after COVID-19 using weather data from Korea to determine whether climate change affects infectious disease viruses through logistic regression analysis. Based on this, we want to classify before and after COVID-19 through a logistic regression model to see how much classification rate we have. In addition, we compare monthly classification rates to see if there are seasonal classification differences.
This study analyzed the knit wear trend, which has gained attention as a sensuous and luxury item, through collection magazines, and used the technique of hand-knit to produce and present the knit wear that was designed based on the study results. Accordingly, the purpose of this study is to raise awareness of the expansion of hand knit's new expression techniques and expression areas and to verify its possibility as a higher value-added product. The trends of hand-knit wear resulted from the analysis of collections divided into the following four groups, and the knit designs were also grouped accordingly: First was "The design using object." The trend survey showed the results that the form of drops or flowers was often used as a factor of object. Accordingly, as for the study design, the drop-knitting technique, which is one of the pattern knitting techniques, was used to present a design that employed drops as the object. Second was "The design matched with woven material." It is a way to emphasize aesthetic formativeness and at the same time to activate the area of knit design by matching woven material, which is different from knit in texture, with knit. This study presented a design that tried to combine knit texture and woven material by connecting denim material with various textures and colors. Third was "The design to express see-through." A sense of showing through knit wear was expressed through changes in the type of thread or knitting technique. In this study, the sense of see-through was expressed using piano wires and wool threads and through changes in the thickness of needle. Fourth was "The design to emphasize coloring." It was analyzed that regarding the production of hand knit, the method of coloring expression was to express points, lines and sides or to create harmony by changing the material's color or texture to show particular objects or shapes. In this study, a jacket was designed using the method to express points, lines and sides by changing the material's color.
International journal of advanced smart convergence
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v.12
no.4
/
pp.300-305
/
2023
This thesis is a study of content development utilizing media outlets to date through digital humans. The trend of global content is that the video content industry, including the character business, is growing. Lil Michela, who was selected as one of the 25 most influential people on the Internet by Time magazine in 2018, Nasua, who appeared in a SK Telecom commercial, and Rosie, who appeared in a Shinhan Bank commercial, are representative. Digital humans, which are driving new content, are computer-generated human characters with various characteristics and are referred to as virtual humans, metahumans, and cyber humans. With the rise of the metaverse after COVID-19, digital humans are being utilized in various forms such as media and marketing as an element of visual content. In the form of media, we can see that the boundaries between the offline and digital worlds are converging, and in the form of marketing, we can see that digital humans connect consumers and products more naturally. In the form of interaction, it is possible to achieve two-way communication through various methods of operation, and through these factors, it is possible to go beyond behavioral communication in the form of memorialization to emotional communication through AI technology. What can be seen through these processes is that through the currently developing digital human production methods and AI functions, not only experts but also non-experts can create quality contents, and new directions of contents will appear, and contents that can provide immediate feedback by bringing consumers and creators closer together have been studied.
Journal of information and communication convergence engineering
/
v.2
no.1
/
pp.58-60
/
2004
Sea level variations and sea surface circulations in the Korean seas were observed by Topex/Poseidon altimeter data from 1993 through 1997. In sea level variations, the West and South Sea showed relatively high variations with comparison to the East Sea. Then, the northern and southern area in the West Sea showed the range of 20∼30cm and 18∼24cm, and the northern west of Jeju island and the southern west of Tsushima island in the South Sea showed the range of 15∼20cm and 10∼15cm, respectively. High variations in the West Sea were results to the inflow in sea surface of Yellow Sea Warm Current (YSWC) and bottom topography. Sea level variations in the South Sea were due to two branch currents (Jeju Warm Current and East Korea Warm Current) originated from Kuroshio Current (KC). In sea surface circulations, there existed remarkably three eddies circulations in the East Sea that are mainly connected with North Korea Cold Current (NKCC), East Korea Warm Current (EKWC) and Tushima Warm Current (TWC). Their eddies are caused basically to the influence of currents in sea surface circulations; Cyclone (0.03 cm/see) in the Wonsan bay off shore with NKCC, and anticyclone (0.06 cm/see) in the southwestern area of Ulleung island with EKWC, and cyclone (0.01 cm/see) in the northeastern area of Tushima island with TWC, respectively.
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