• 대한소아치과학회지
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• 제28권3호
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• pp.530-534
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• 2001

많은 치과 임상가들은 아말감을 치질에 접착시키기 위해서 여러 접착재료를 이용해왔다. 이 런 술식의 장점으로는 미세누출의 감소로 인한 술후과민증의 감소, 변연파절의 감소, 삭제 후 치질의 강화, 적은 유지형태에서의 수복물의 유지등이 제시되어 왔다. 실제로 임상적 상황에서 이러한 술식의 장점을 확인할 필요가 있다. 이런 접착제가 임상적 환경에서 어떠한 잇점을 보이지 않는다면 시간과 비용을 낭비하는 이런 술식을 정당화하지 못할 것이다. 본 연구에서는 73개의 치아를 대상으로 하여 I급 와동과 II급 와동에 접착형과 비접착형 아말감으로 수복하였다. 접착제로는 Fuji I Glass Ionomer luting cement를 이용하였다. 평균 2년 후에 변연적합성을 평가하였으나 접착형 아말감과 비접착형 아말감 사이에 유의한 차이는 없었다.

• 대한방사성의약품학회지
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• 제1권1호
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• pp.62-73
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• 2015

We developed an evans blue-indocyanine green-$^{99m}Tc$-human serum albumin conjugate for sentinel lymph node mapping and we describe its unique potential usage for clinical implications. This conjugate has combined the strengths of visible blue dye, near-infrared fluorescence and radioisotope into one single conjugate without any additional weakness/disadvantage. All the components of evans blue-indocyanine green-$^{99m}Tc$-human serum albumin are safe and of low cost, and they have already been clinically used. This conjugate was stable in the serum, it showed a long retention time in the lymphatic system and the lymph nodes showed a much higher signal-to-noise ratio after the conjugate was injected intradermally into the paw of mice. Both the single-photon emission computed tomography and near-infrared fluorescent images of the mice were successfully obtained at the same time as the excised sentinel lymph nodes showed blue color. The visual color, near-infrared fluorescence and gamma ray from this agent could be complementary for each other in all the steps of sentinel lymph node sampling: exploring and planning sentinel lymph node before excision with visualization of the exact sentinel lymph node location during an operation. Therefore, the triple modal agent will possibly be very ideal for sentinel lymph node mapping because of the high signal-to-noise ratio for non-invasive imaging and its complementary multimodal nature, easy preparation and safety. It is promising for clinical applications and it may have great advantages over the traditional single modal methods.

• 한국물환경학회지
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• 제22권2호
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• pp.342-348
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• 2006

Changes in water quality and algal growth according to the differences in the inflow volume were investigated in the Daecheong Lake from 1998 to 2001. Until year 2000, inflow volume considerably depended on the rainfall throughout the basin. However, the correlation was low since 2001 when water storage in the upstream Yongdam Lake was started. According to inflow volume-TP relationship analyses, significant correlation was found at up- and middle-stream sites, excluding down-stream site of the Daechong Lake. For chlorophyll-a, correlation was found with flow volume at all sites except for Choo-So. In a dry year, although nutrients loads were relatively lower than those in rainy years, there were higher concentrations of chlorophyll-a and massive bloom of Microcystis. Limiting factors for algal growth seems to be not the volume of nutrients load but retention time and physical disturbance of the water body influenced by inflow volume. Thus, in the Daecheong lake, it would be more important to focus on the management of eutrophication in dry years than in rainy ones.

• 동의생리병리학회지
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• 제19권3호
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• pp.785-791
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• 2005

Corydalis Tuber has traditionally been used for the treatment of water retention in the body. Administration of the aqueous extract of Corydalis Tuber has been known to be effective for the control of pain and treatment of arthritis. It was reported that Corydalis Tuber possesses anti-inflammatory activity and modulates the intestinal immune system. The effect of Corydalis Tuber against LPS-stimulated expressions of COX-2, iNOS, and $IL-1{\beta}$ in cells of the murine RAW 264.7 macrophages was investigated using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, reverse transcription-polymerase chain reaction (RT-PCR), $PGE_2$ immunoassay, and NO detection. The aqueous extract of Corydalis Tuber was shown to suppress $PGE_2$ production by inhibition on the LPS-stimulated enhancement of COX-2 enzyme activity, $IL-1{\beta}$, and iNOS expression in the RAW 264.7 macrophages. Present results suggest that Corydalis Tuber exerts anti-inflammatory and analgesic effects probably by suppressing of COX-2, iNOS, and $IL-1{\beta}$ expressions, resulting in inhibition of $PGE_2$ synthesis. Corydalis Tuber has anti-inflammatory and analgesic effects probably by suppressing of COX-2, iNOS, and $IL-1{\beta}$ mRNA expressions, resulting in inhibition of $PGE_2$ and NO synthesis.

• Journal of Pharmaceutical Investigation
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• 제22권3호
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• pp.197-204
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• 1992

A gas chromatographic method using nitrogen phosphorous selective detection was developed for simultaneous determination of haloperidol and its metabolite, reduced haloperidol, in human plasma. Combelen was used as internal standard, The method involved extraction and trimethylsilylation followed by the injection of $2-4\;{\mu}l$ of benzene layer, which was used to dissolve the trimethylsilylated derivatives of haloperidol and reduced haloperidol, onto SE-54 column [5% phenyl methyl silica fused capillary column, $16m{\times}0.22\;mm$ $(I.D.){\times}0.33\;{\mu}m$ (coated thickness)]. The temperature of column oven was programmed from $200^{\circ}C\;to\;300^{\circ}C$ at the increase rate of $10^{\circ}C/min and also the temperatures of injector and detector were set at $300^{\circ}C$. Helium was used as carrier gas and its flow rate was maintained at 30 ml/min. The detection was conducted with nitrogen phosphorous selective detector. The retention times for combelen, reduced haloperidol and haloperidol were found to be 9.14, 9.75 and 9.99 min, respectively. The detection limits for haloperidol and reduced haloperidol in human plasma were both 0.2 ng/ml. The coefficients of variation of the intra-assay were generally low (below 9.8%). The mean absolute recoveries of added haloperidol and reduced haloperidol from plasma were 72% and 84%, respectively. No interferences from endogenous substances were found.

• 대한치과의사협회지
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• 제45권12호통권463호
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• pp.753-760
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• 2007

노화가 진행되고 있는 중, 장년층의 교정치료시에 통상적인 교정치료의 방법과 함께 다음과 같은 사항을 고려하여야 한다. 1. 치주질환 존재시 교정치료전 치주치료를 선행하여야 한다. 2. 발치 치료가 필요할 경우 치주 상태 및 치아 상태를 고려하여 발치할 치아를 선정하여야 한다. 3. 기존 보철물 존재시 보철물의 상태, 고정원으로 사용여부, 크기 조절 필요 여부, 환자의 경제적 상황 등을 고려햐여 처치한다. 4. 치료 종료 후 가철식 유지장치보다는 고정식 보정장치를 이용하여 치아의 유지력을 보강하는 것이 권장된다.

• 대한소아치과학회지
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• 제30권4호
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• pp.673-677
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• 2003

선천적 무설증은 매우 드물게 보고되는 증상이다. 무설증을 가진 환자는 구개 이상, 하순 결손, 하악 측절치 결손 등을 포함한 하악골의 발육부전을 나타낸다. 무설증의 원인은 밝혀지지 않았으나 유전적 요인이나 발생 4주시기에 기형유발물질의 영향으로 추정되고 있다. 무설증의 치료는 혀를 재건해주는 외과적 술식과 하악골의 성장을 돕는 교정적 술식, 하악골의 길이를 늘리는 distraction osteogenesis 등이 있으며 무설증의 정도에 따라 달라진다. 본 증례는 선천적 무설증과 situs inversus(장기의 좌우가 바뀐 상태)를 가진 6세 여아에서 무설증으로 인한 하악골의 횡적 수축을 악정형 장치를 이용하여 치료하였으며 향후 2차 교정과 외과적 수술을 계획하기에 양호한 결과를 얻을 수 있었다.

• 대한소아치과학회지
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• 제31권4호
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• pp.630-635
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• 2004

정중과잉치의 원인은 잘 알려지지는 않았지만 dental lamina의 hyperactivity에 의해 발생한다는 가설이 가장 많이 받아들여지고 있다. 이러한 정중과잉치의 병발증으로는 주변 영구절치의 맹출 장애, 만곡 치근, 치근흡수, primordial 혹은 follicular cyst의 형성, 회전, 이환된 부위의 총생 및 비정상적인 정중이개를 일으킬 수 있다. 이러한 이유로 영구전치의 회전이 야기되면 보통 공간의 부족은 적거나 없으며 재발이 흔하므로 과개선이 요구된다. 재발의 방지를 위해서는 조기치료, 과개선, 긴 보정기간, 적절한 접촉면의 형성, 짝힘의 사용, 그리고 수술적인 방법 등이 제안되어왔다. 이에 저자는 정중과잉치로 인하여 심하게 회전된 상악중절치를 주소로 내원한 환아에서 교정적, 외과적 술식을 이용하여 양호한 결과를 얻은 두 증례를 보고하는 바이다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2013년도 제45회 하계 정기학술대회 초록집
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• pp.288-288
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• 2013

Lithium-ion battery (LIB) is one of the most important rechargeable battery and portable energy storage for the electric digital devices. In particular, study about the higher energy capacity and longer cycle life is intensively studied because of applications in mobile electronics and electric vehicles. Generally, the LIB's capacity can be improved by replacing anode materials with high capacitance. The graphite, common anode materials, has a good cyclability but shows limitations of capacity (~374 mAh/g). On the contrary, silicon (Si) and germanium(Ge), which is same group elements, are promising candidate for high-performance LIB electrodes because it has a higher theoretical specific capacity. (Si:4200 mAh/g, Ge:1600 mAh/g) However, it is well known that Si volume change by 400% upon full lithiation (lithium insertion into Si), which result in a mechanical pulverization and poor capacity retention during cycling. Therefore, variety of nanostructure group IV elements, including nanoparticles, nanowires, and hollow nanospheres, can be promising solution about the critical issues associated with the large volume change. However, the fundamental research about correlation between the composition and structure for LIB anode is not studied yet. Herein, we successfully synthesized various structure of nanowire such as Si-Ge, Ge-Carbon and Si-graphene core-shell types and analyzed the properties of LIB. Nanowires (NWs) were grown on stainless steel substrates using Au catalyst via VLS (Vapor Liquid Solid) mechanism. And, core-shell NWs were grown by VS (Vapor-Solid) process on the surface of NWs. In order to characterize it, we used FE-SEM, HR-TEM, and Raman spectroscopy. We measured battery property of various nanostructures for checking the capacity and cyclability by cell-tester.

• 유기물자원화
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• 제19권2호
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• pp.49-54
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• 2011

본 연구는 혐기성 수소 발효 반응조의 유출수를 기질로 이용하여 anaerobic baffled reactor (ABR) 및 anaerobic sequencing batch reactor (ASBR) 형태에 따른 혐기성 메탄 발효 성능을 평가하였다. 두 개의 반응조는 유기물 부하율 $1.0kg\;COD/m^3{\cdot}d$와 수리학적 체류시간 20일에서 운전을 수행하였다. ABR과 ASBR의 초기 운전 기간에서 메탄 발생량은 각각 0.04 L/L/d와 0.19 L/L/d로 나타났으며, ABR과 ASBR의 최대 메탄 발생량은 각각 0.25 L/L/d와 0.31 L/L/d로 나타났다. ABR과 ASBR의 초기 운전 기간에서 COD 제거율은 각각 89%와 92%로 나타났다. 정상 상태에 도달한 후에는 ABR과 ASBR의 COD 및 VS의 제거율은 각각 90% 이상 유지되었다. 비메탄 활성도는 미생물이 기질에 적응함에 따라 반응조에 상관없이 증가하였다.