• Journal of Preventive Medicine and Public Health
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• 제39권4호
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• pp.346-352
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• 2006

Objectives: The purposes of this study were to propose a screening schedule for the early detection of breast cancer among Korean women, as based on the statistical model, and to compare the efficacy of the proposed screening schedule with the current recommendations. Methods: The development of the screening schedule for breast cancer closely followed the work of Lee and Zelen (1998). We calculated the age-specific breast cancer incidence rate from the Korea Central Cancer Registry (2003), and then we estimated the scheduling of periodic examinations for the early detection of breast cancer, using mammography, and based on the threshold method. The efficacy of the derived screening schedule was evaluated by the schedule sensitivity. Results: For estimating the screening schedule threshold method, we set the threshold value as the probability of being in the preclinical stage at age 35, the sensitivity of mammography as 0.9 and the mean sojourn time in the preclinical stage as 4 years. This method generated 14 examinations within the age interval [40, 69] of 40.0, 41.3, 42.7, 44.1, 45.4, 46.7, 48.0, 49.3, 51.0, 53.2, 55.3, 57.1, 59.0 and 63.6 years, and the schedule sensitivity was 75.4%. The proposed screening schedule detected 85.2% (74.5/87.4) of the cases that could have been detected by annual screening, but it required only about 48.7% (14.0/30.0) of the total number of examinations. We also examined the threshold screening schedules for a range of sensitivities of mammography and the mean sojourn time in the preclinical stage. Conclusions: The proposed screening schedule for breast cancer with using the threshold method will be helpful to provide guidelines for a public health program for choosing an effective screening schedule for breast cancer among Korean women.

• Journal of the Korean Data and Information Science Society
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• 제21권1호
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• pp.129-138
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• 2010

본 논문에서는 우리나라 자궁경부암 조기검진 권고안을 바탕으로 검진주기 및 검진연령 변화에 따른 다양한 검진전략들의 효율성을 검토하고 비용-효과분석을 통하여 비용-효과적인 대안을 찾아 제시하고자 하였다. 한국중앙암등록본부의 2002년 자료와 확률모형을 이용하여 고려된 검진전략을 검진의 민감도와 무증상 상태에 있는 암 환자를 발견할 확률 및 검진비용을 추정하여 비용-효과분석을 시행하였다. 연구결과 비용-효과적인 측면에서 자궁경부세포검사를 이용한 35세부터 65세까지 3년 주기의 검진전략이 상대적으로 높은 효율성을 나타내었다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제29권4호
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• pp.172-177
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• 2018

Objectives: We examined the agreement between the Autism Diagnostic Observation Schedule (ADOS) and the Childhood Autism Rating Scale (CARS) in the diagnosis of autism spectrum disorder. Methods: The ADOS and CARS scores of 78 children were retrospectively collected from a chart review. A correlation analysis was performed to examine the concurrent validity between the two measures. Using the receiver operating characteristic (ROC) curve, we determined the optimal cut-off score of the CARS for identifying autism spectrum disorder. Results: The CARS score was significantly correlated with the ADOS score (r=0.808, p<0.001). Taking ADOS as the ideal standard, the optimal cut-off scores of CARS for identifying autism and autism spectrum were 30 and 24.5, respectively. Conclusion: We determined the optimal cut-off scores of CARS for screening and diagnosing autism spectrum disorder.

• 한국컴퓨터정보학회논문지
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• 제25권8호
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• pp.47-54
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• 2020

발달장애는 영유아 기부터 시작하는 뇌 신경계 발달장애들의 집합으로 언어 및 의사소통, 인지력, 사회성 등의 측면에서 이루어져야 할 발달이 심하게 지체되거나 성취되지 않은 장애를 의미한다. 이러한 발달장애 진단에는 아동의 얼굴 표정과 같은 감정표현의 의미와 맥락 등 비언어적 반응에 대한 관찰로 이루어진다. 이를 사람이 측정기에는 상당히 주관적인 판단이 개입하게 되어 객관적인 기술이 필요하다. 따라서 본 연구에서는 영유아/아동의 언어, 비언어적 행동 반응을 관찰하는 ADOS(Autism Diagnostic Observation Schedule)와 BeDevel(Behavior Development Screening for Toddler) 검사에서 검사자와 피검사자간의 상호작용이 녹화된 영상을 리빙랩 환경에서 획득하여 인공지능 기반의 비정상적/상동적 행동 인지 기술 개발에 필요한 영상 및 음성 데이터 확보를 목표로 한다.

• 보건교육건강증진학회지
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• 제23권4호
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• pp.29-45
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• 2006

Objectives: The aim of this study was to determine the distribution of stages of adoption in stomach cancer screening and elucidate differences among stages. Methods: A randomly selected sample of 712 Korean males and females aged 40 years or over were interviewed. Stomach cancer screening intention and behavior, sociodemographic characteristics, beliefs, self-efficacy and reinforcing characteristics were assessed. Results: The majority of participants were not on-schedule screening(unaware 3.2%, unengaged 20.8%, deciding about acting 24.0%, decided not to act 9.6%, decided to act 14.5%, acting 9.7%, maintenance 18.3%). Perceived susceptibility, perceived barriers, self-efficacy, other cancer screening experiences were significantly associated with higher compared to lower Precaution Adoption Process Model(PAPM) stages. Conclusions: This study appears to be applicable of the Precaution Adoption Process Model to understanding stomach cancer screening behavior. Our results suggest that it is needed to develop the tailored message for adherence of stomach cancer screening.

• 대한화학회지
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• 제52권3호
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• pp.239-248
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• 2008

활성탄소섬유(ACF; activated carbon fiber)를 흡착제로 사용한 고상추출법(SPE; solid phase extraction)으로 수용액 시료 중에 존재하는 특정화학물질(schedule chemicals)의 분석법을 연구하였다. 본 연구에 사용된 특정화학물질은 화학작용제류의 가수분해 생성물과 유사작용제로 사용되는 알킬포스포네이트류, 티오디글리콜 등 14종이었다. 분석을 위한 추출물의 실릴 유도체화 반응에서 피리딘을 사용하여 특히 3-quinuclidinol의 유도체화 반응 효율을 높일 수 있었다. 물 시료에서 아민류의 추출 회수율을 개선하기 위하여 SPE-ACF 튜브에 시료를 부하하기 전에 5% triethylamine/MeOH(1 mL) 용액으로 SPE-ACF 튜브를 세척한 후에 시료를 SPE-ACF에 부하하는 방법으로 추출 회수율을 증대시킬 수 있었다. 이 연구를 통해서 수용액 시료에서 특정화학물질을 신속히 검출할 수 있는 최적 조건을 선정하였다.

• Archives of Pharmacal Research
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• 제3권2호
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• pp.75-78
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• 1980

Potential antinumor activity of sixteen Korean medicinal plants was tested against leukemia SN 36, murine tomor model. Survival studies by measuring life span indicated that Morus alba (Moraceae), Verbascum phlomoides (Scrophulariaceae), Curcuma longa (Zingbieraceae), Torilis japonica (Umbelliferae), Bupleurum falcatum (Umbelliferae) and Codonopsis pilosula (Campanulaceae) exhibited significant antitumor activity with the dose-schedule employed in the experiment. Methanol (70%) extracts of Platycodon gradiflorum (Campanulaceae), Bupleurum longeradiatum (Umbelliferae) and Asiasarum sieboldii (Aristolochiaceae) showed rather potent toxicity.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10053-10056
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• 2015

The human papilloma virus (HPV) is the main aetiological agent for cervical cancer, one of the most frequent cancers observed in women throughout the world. There are effective programs for reducing the incidence of cervical cancer with HPV vaccination. The objective of this study was to discuss the applicability of the HPV vaccination and the role of nurses in prevention of cervical cancer. Use of bivalent and quadrivalent vaccines has been initiated against the types of HPV which are the primary cause of cancer. The quadrivalent HPV vaccination has entered into the routine vaccination schedule in many European countries for use in children and adolescents between 9-15 years of age and for women between 16-26 years of age, whereas it has been proposed that the bivalent vaccination should be given to girls between 9-18 years of age. While cervical cancer is among the cancers that can be prevented, it is essential to continue screening tests while introducing vaccination in a systematic manner for protection. On this subject, among the most important roles of nurses is to implement the screening programs by fulfilling the caregiving, training and consultancy roles for the society and especially, for high risk groups and to increase the awareness of the people.

• Asian Pacific Journal of Cancer Prevention
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• 제16권7호
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• pp.2637-2643
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• 2015

Background: It has been proven that an individuals health behavior is determined through a series of processes. This study aimed to assess the stages of adoption of breast cancer screening, and to identify the factors relating to progress through these stages. Materials and Methods: There were 202 female participants aged 20-59 years who were living in Chungbuk, South Korea. They were informed of the study purpose and agreed to participate. Data were collected from October 2010 to January 2011 by assessing the breast cancer screening stage, health beliefs, socio-demographic factors, and other facilitating factors. The participant current stage of adoption of breast cancer screening was classified using the Precaution Adoption Process Model (PAPM), and the various PAPM stages were compared with each other to identify factors likely to determine progress between stages. The data were analyzed using the ${\chi}^2$-test, ANOVA, Duncan test, and multiple logistic regression. Results: Approximately half of all participants were not on-schedule for breast self-examination and mammography (unaware, 9.4% and 11.4%, unengaged, 8.4% and 5.0%, undecided, 20.3% and 17.8%, decided not to act, 1.5% and 1.0%, decided to act, 13.4% and 15.3%, respectively). The factors likely to determine the progress from one stage to another were age, marital status, exposure to media information about breast cancer, self-efficacy, and perceived severity. Conclusions: These results suggest that it is necessary to develop a tailored message for breast cancer screening behavior.

• Journal of Preventive Medicine and Public Health
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• 제38권3호
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• pp.351-358
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• 2005

Objectives : Dementia has rapidly increased with the prolongation of life expectancy and aging in Korea. This study was conducted to estimate the prevalence of, and find related factors for, dementia in an urban elderly population, using a newly developed screening method. Methods : Seven hundred and six people, aged over 65 years-old, in Dong district of Gwangju, Korea, were recruited using stratified cluster sampling, and completed Korean version of Geriatric Mental State Schedule B3 (GMS B3-K), the Korean version of the Community Screening Interview for Dementia (CSID-K) and modified 10 word list-learning from the Consortium to Establish a Registry of Alzheimer's Disease (CERAD). Dementia was diagnosed by an algorithm derived from all three of these measures. Results : The crude and age adjusted prevalence rates of dementia were 13.0 and 11.5%, respectively. Age, education, marital status and a history of cerebrovascular disease were identified as factors related with dementia. Conclusions : The new instrument, using the GMS B3-K, CSID-K and modified 10 word list-learning from the CERAD, was considered effective as a community screening and diagnostic tool for dementia. The results of this study can also be used to develop a community-based prevention and management system for dementia in the future.