Journal of Preventive Medicine and Public Health

  • 제39권4호
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  • Pages.346-352
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  • 2006
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  • 1975-8375(pISSN)
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  • 2233-4521(eISSN)
대한예방의학회 (The Korean Society for Preventive Medicine)
권호 표지

유방암 조기진단을 위한 검진주기 결정에 대한 연구

A Study on Scheduling Periodic Examinations for the Early Detection of Breast Cancer in Korea

  • 정성화 (연세대학교 대학원 보건학과) ;
  • 강대룡 (연세대학교 의과대학 예방의학교실) ;
  • 허남욱 (연세대학교 의과대학 예방의학교실) ;
  • 김진흠 (수원대학교 통계정보학과) ;
  • 이순영 (아주대학교 의과대학 예방의학교실) ;
  • 정상혁 (이화여자대학교 의과대학 예방의학교실) ;
  • 남정모 (연세대학교 의과대학 예방의학교실)
  • Jeong, Seong-Hwa (Department of Public Health, Graduate School of Yonsei University) ;
  • Kang, Dae-Ryong (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Hur, Nam-Wook (Department of Preventive Medicine, Yonsei University College of Medicine) ;
  • Kim, Jin-Heum (Department of Applied Statistics, The University of Suwon) ;
  • Lee, Soon-Young (Department of Preventive Medicine and Public Health, School of Medicine, Ajou University) ;
  • Jung, Sang-Hyuk (Department of Preventive Medicine, College of Medicine, Ewha Womans University) ;
  • Nam, Chung-Mo (Department of Preventive Medicine, Yonsei University College of Medicine)
  • 발행 : 2006.07.31
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초록

Objectives: The purposes of this study were to propose a screening schedule for the early detection of breast cancer among Korean women, as based on the statistical model, and to compare the efficacy of the proposed screening schedule with the current recommendations. Methods: The development of the screening schedule for breast cancer closely followed the work of Lee and Zelen (1998). We calculated the age-specific breast cancer incidence rate from the Korea Central Cancer Registry (2003), and then we estimated the scheduling of periodic examinations for the early detection of breast cancer, using mammography, and based on the threshold method. The efficacy of the derived screening schedule was evaluated by the schedule sensitivity. Results: For estimating the screening schedule threshold method, we set the threshold value as the probability of being in the preclinical stage at age 35, the sensitivity of mammography as 0.9 and the mean sojourn time in the preclinical stage as 4 years. This method generated 14 examinations within the age interval [40, 69] of 40.0, 41.3, 42.7, 44.1, 45.4, 46.7, 48.0, 49.3, 51.0, 53.2, 55.3, 57.1, 59.0 and 63.6 years, and the schedule sensitivity was 75.4%. The proposed screening schedule detected 85.2% (74.5/87.4) of the cases that could have been detected by annual screening, but it required only about 48.7% (14.0/30.0) of the total number of examinations. We also examined the threshold screening schedules for a range of sensitivities of mammography and the mean sojourn time in the preclinical stage. Conclusions: The proposed screening schedule for breast cancer with using the threshold method will be helpful to provide guidelines for a public health program for choosing an effective screening schedule for breast cancer among Korean women.

키워드

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