• Journal of Microbiology and Biotechnology
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• v.22 no.5
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• pp.708-720
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• 2012

In this study, we assessed the effects of ginsenoside Re (GRe) administration on repeated immobilization stress-induced behavioral alterations using the forced swimming test (FST), the elevated plus maze (EPM), and the active avoidance conditioning test (AAT). Additionally, we examined the effect of GRe on the central adrenergic system by observing changes in neuronal tyrosine hydroxylase (TH) immunoreactivity and brain-derived neurotrophic factor (BDNF) mRNA expression in the rat brain. Male rats received 10, 20, or 50 mg/kg GRe (i.p.) 30 min before daily exposures to repeated immobilization stress (2 h/day) for 10 days. Activation of the hypothalamic-pituitary-adrenal (HPA) axis in response to repeated immobilization was confirmed by measuring serum levels of corticosterone (CORT) and the expression of corticotrophin-releasing factor (CRF) in the hypothalamus. Repeated immobilization stress increased immobility in the FST and reduced open-arm exploration in the EPM test. It also increased the probability of escape failures in the AAT test, indicating a reduced avoidance response. Daily administration of GRe during the repeated immobilization stress period significantly inhibited the stress-induced behavioral deficits in these behavioral tests. Administration of GRe also significantly blocked the increase in TH expression in the locus coeruleus (LC) and the decrease in BDNF mRNA expression in the hippocampus. Taken together, these findings indicate that administration of GRe prior to immobilization stress significantly improved helpless behaviors and cognitive impairment, possibly through modulating the central noradrenergic system in rats. These findings suggest that GRe may be a useful agent for treating complex symptoms of depression, anxiety, and cognitive impairment.

• Korean Parent-Child Health Journal
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• v.6 no.1
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• pp.46-58
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• 2003

The purpose of this study is to investigate the effect on maternal perception of her infant and the infant's behavior development through maternal education designed to provide information of the capabilities and the individual characteristics of her infant. The subjects were 48 pairs of normal infants and mothers at three different hospitals, 24 pairs for the intervention group and 24 pairs of the control group. The survey was conducted from July 30 to October 6, 2001. The results of this study were as the following. A maternal perception of her infant was significantly different between the two groups, more positive in the intervention group than in the control group. The information and understanding of behavioral characteristics of the infant are an important factor influencing maternal perception for her infant and general development of the infant. On the basis of these results, the educational intervention method of this study may be worth utilizing in nursing practice. The practitioners of hospitals have to establish a system that it offers an education of understanding the infant's behavioral characteristics during the hospitalization after delivery.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.9
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• pp.2529-2549
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• 2023

For effectively lowering down the risk of cyber threating, the zero-trust architecture (ZTA) has been gradually deployed to the fields of smart city, Internet of Things, and cloud computing. The main concept of ZTA is to maintain a distrustful attitude towards all devices, identities, and communication requests, which only offering the minimum access and validity. Unfortunately, adopting the most secure and complex multifactor authentication has brought enterprise and employee a troublesome and unfriendly burden. Thus, authors aim to incorporate machine learning technology to build an employee behavior analysis ZTA. The new framework is characterized by the ability of adjusting the difficulty of identity verification through the user behavioral patterns and the risk degree of the resource. In particular, three key factors, including one-time password, face feature, and authorization code, have been applied to design the adaptive multifactor continuous authentication system. Simulations have demonstrated that the new work can eliminate the necessity of maintaining a heavy authentication and ensure an employee-friendly experience.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.2
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• pp.105-118
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• 2018

Generic medicine (GM), which is an alternative drug product for branded medicine (BM), is used less in Japan than in other OECD countries. Therefore, we investigate why the medical consumers of Japan avoid the use of GMs even though the efficacy and safety of the medicines have already been proven. We theorize that effectiveness or risk of GMs are related to the consumer attitude toward GMs is affected by the behavioral approach/activation system (BAS) which promotes actions to reach the desired state, and the behavioral inhibition system (BIS) which suppresses behaviors to avoid negative outcomes. To see which of the BAS and BIS dimensions are related to GM usage, we surveyed 374 Japanese consumers and found that Quality, Efficacy, Safety, & Cost-effectiveness with the BAS, and Functional Risk, Financial Risk, Social Risk, Physical Risk, Psychological Risk, & Time Risk with the BIS had a significant effect on consumer attitude to GMs. These results are important in that they 1), confirm the role of BAS/BIS in attitudes to GMs, 2), provide guidelines when marketing GMs, 3), help governments promote the use of GMs as a cost-saving measure, and 4), guide future surveys regarding consumer attitudes to GMs.

• Molecules and Cells
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• v.39 no.10
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• pp.750-755
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• 2016

Although innate color preference of motile organisms may provide clues to behavioral biases, it has remained a longstanding question. In this study, we investigated innate color preference of zebrafish larvae. A cross maze with different color sleeves around each arm was used for the color preference test (R; red, G; green, B; blue, Y; yellow). The findings showed that 5 dpf zebrafish larvae preferred blue over other colors (B > R > G > Y). To study innate color recognition further, tyrosinase mutants were generated using CRISPR/Cas9 system. As a model for oculocutaneous albinism (OCA) and color vision impairment, tyrosinase mutants demonstrated diminished color sensation, indicated mainly by hypopigmentation of the retinal pigment epithelium (RPE). Due to its relative simplicity and ease, color preference screening using zebrafish larvae is suitable for high-throughput screening applications. This system may potentially be applied to the analysis of drug effects on larval behavior or the detection of sensory deficits in neurological disorder models, such as autism-related disorders, using mutant larvae generated by the CRISPR/Cas9 technique.

• Journal of Korean Academy of Nursing
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• v.39 no.5
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• pp.741-750
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• 2009

Purpose: The purpose of this study was to identify the prevalence of cognitive impairment, behavioral problems, and the state of mental health for elderly Korean people who have been institutionalized. Methods: A cross-sectional, nationwide survey was performed using an anonymous questionnaire. The participants in this study were 2,521 institutionalized elderly Korean people. A proportional stratified random sampling method was employed. Results: 1) Elders admitted to subacute hospitals and long term care (LTC) facilities showed a higher level of cognitive impairment compared to elders admitted to acute care hospitals. 2) Elders confined in LTC facilities showed a higher level of behavioral problems compared to elders in acute or subacute hospitals. 3) Elders admitted to subacute hospitals and LTC facilities showed more serious mental health problems, such as depression or suicidal ideation, compared to elders in acute care hospitals. Conclusion: The results of this study indicate that the severity of cognitive-behavioral or mental health problems do not match well with type of care setting. Therefore, health personnel working with elderly people should be provided guidance on detection and management of cognitive-behavioral and mental health problems. The necessity of a decision support system for eligibility and placement in long-term care is also discussed.

• Journal of Distribution Science
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• v.19 no.11
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• pp.91-98
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• 2021

Purpose: With the interest and ability in recruitment, it is totally worthy to discover how is labor market developed in Vietnam since the existence of the Internet. Considering employers as well as recruiters similar to jobseekers in term of technology adoption of job distribution, they should be treated fairly while performing their scopes of work. This paper aims to explore how employers perceive online recruiting platform as a supportive system, and this is to find out contributions of external factors regarding Job Boards behavioral intention to use. Research design, data and methodology: Conceptual framework tests the hypotheses involving in recruitment websites. Results: The results suggest that Board of Directors (BoD) or direct middle managers need to pay more attention on how their workforce performs through various channels of recruitment - both formal and informal, such as Linkedin or Facebook rather than a few compulsory job boards - no longer being accessed with high performance expectancy. However, the technology adaptation of recruitment is still a controversial issue due to its access to privacy of users. Conclusion: Therefore, employers should be more careful on how their personal contacts are going to be delivering without consent. Secondly, keeping systems up to date and "connected" is essential for both employees and employers.

• Culinary science and hospitality research
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• v.19 no.4
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• pp.161-175
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• 2013

This study investigates the impact of the attributes of the eco-friendly agricultural products traceability system on perceived value and behavioral intention. Empirical subjects are those who live in Seoul and Gyeonggi province, over the age of 20 and have experience of buying eco-friendly agricultural products though department stores, discount stores and specialized eco-friendly product stores. After distributing 550 copies of questionnaire from April 10th, 2013 to May 9th, 2013, 470 copies(85.5%) are used for a final statistical analysis of the survey after excluding the copies with biased opinions or missing values. The results of this study show sufficient theoretical base for future research by verifying a causal relationships between the attributes of eco-friendly agricultural products traceability system such as reliability, safety and innovation, and consumers' perceived value and behavioral intention. Therefore, producers should correctly record producing history base so that consumers can continue to use the system. The traceability system can not only satisfy consumers by enhancing transparent management and producing systems for eco-friendly products but also guarantee us to eat all products we get without worries.

• Korean Circulation Journal
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• v.53 no.1
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• pp.17-30
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• 2023

Background and Objectives: To evaluate the impact of smoking in young adults on the risk of cardiovascular disease (CVD) and the clustering effect of behavioral risk factors such as smoking, obesity, and depression. Methods: A Korean nationwide population-based cohort of a total of 3,280,826 participants aged 20-39 years old who underwent 2 consecutive health examinations were included. They were followed up until the date of CVD (myocardial infarction [MI] or stroke), or December 2018 (median, 6 years). Results: Current smoking, early age of smoking initiation, and smoking intensity were associated with an increased risk of CVD incidence. Even after quitting smoking, the risk of MI was still high in quitters compared with non-smokers. Cigarette smoking, obesity, and depression were independently associated with a 1.3-1.7 times increased risk of CVD, and clustering of 2 or more of these behavioral risk factors was associated with a 2-3 times increased risk of CVD in young adults. Conclusions: In young adults, cigarette smoking was associated with the risk of CVD, and the clustering of 2 or more behavioral risk factors showed an additive risk of CVD.

• Journal of Internet Computing and Services
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• v.19 no.2
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• pp.43-48
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• 2018

Various artifacts that are produced as software R&D project progresses contain research plan, research report, software requirements and design descriptions, etc. When conducting a software R&D project, it is necessary to confirm that the developed system has implemented its research requirements well. However, various research results make it difficult to design appropriate tests. So, there is a practical need for us to comprehensively handle the planning, execution, and reporting of software test for finding and verifying information related to the research. In this paper, we propose a useful method for software test process in R&D project which supports model based software testing. The proposed method supports automation of test design and generation of test data by explicitly separating each step of System Under Test (SUT). The method utilizes the various models representing the control flow of the function to extract the information necessary for testing the system. And it supports a systematic testing process based on TMMi and ISO 29119. Finally, we show the validity of the method by implementing a prototype with basic functionality to generate test data from software behavioral models.