• 생약학회지
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• 제48권1호
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• pp.63-69
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• 2017

Saururus chinensis (Lour.) Baill. (Saururaceae) has been used as a traditional medicine for the treatment of dysuria, leukorrhea, eczema, jaundice and ascites in Korea, China and Japan. Ethanol extract of S. chinensis was successively partitioned as methylene chloride, ethyl acetate, n-butanol and $H_2O$ soluble fractions. Among those fractions the ethyl acetate soluble fraction showed the most potent DPPH radical scavenging and superoxide quenching activities. To verify antioxidant activities of ethyl acetate fraction, we checked the activities of superoxide dismutase (SOD) and catalase, and intracellular ROS level and oxidative stress tolerance in Caenorhabditis elegans. Furthermore, to see if increased stress tolerance of worms by treating of ethyl acetate fraction was due to regulation of stress-response gene, we quantified SOD-3 expression using transgenic strain. Consequently, ethyl acetate fraction elevated SOD and catalase activities of C. elegans, and reduced intracellular ROS accumulation in a dose-dependent manner. Moreover, ethyl acetate fraction-treated CF1553 worms exhibited significantly higher SOD-3::GFP intensity.

• 한국자원식물학회지
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• 제20권5호
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• pp.471-474
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• 2007

종근크기에 따른 삼백초의 생산성을 구명하여 재배법 확립의 기초자료를 제공하고자 종근 직경 5mm 미만 등 4처리를 두어 시험한 결과, 출아는 종근직경 9mm 이상에서 빨리 출아되었으며, 최종 출아수도 종근 직경 6mm의 8.0개/$m^2$에 비하여 $84{\sim}109%$ 많았다. 줄기의 생육은 종근 직경 6mm에서 초장과 경태가 길거나, 굵어 양호한 경향이었으나, 분얼수는 종근크기가 클수록 많았다. 엽의 생육 중 상품엽수는 종근 직경 9mm 이상에서 많았으나, 엽장, 엽폭, 비상품엽수는 종근 크기 간에 차이가 인정되지 않았다. 상품 경엽의 건물중은 종근 직경 9mm 이상에서 높아, 종근 직경 6mm 대비 $35{\sim}37%$ 높았다. 이상의 결과에서 삼백초 재배 시 종근의 크기는 출아율과 경엽중이 많은 9mm가 가장 적합한 것으로 판단된다.

• 대한동의생리학회:학술대회논문집
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• 대한동의생리학회 2004년도 하계학술대회 및 임시정기총회
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• pp.12-12
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• 2004

• 한국자원식물학회지
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• 제20권2호
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• pp.129-132
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• 2007

삼백초 1회 수확 후 질소 추비량에 따른 생육 및 수량을 검토하여 재배법 확립의 기초자료를 제공하고자, 무시용 등 4처리를 두어 2002년부터 3년간 시험한 결과, 초장, 엽의 크기, 경태, 절수, 상품엽수, 분얼수 등 경엽과 근경의 생육은 1차 수확 후 질소 추비량이 많을수록 길거나, 굵거나, 많은 경향으로 양호하였다. 경엽수량은 질소 추비량이 많을수록 증가되어 무시용 158kg/10a 대비 3, 6, 9kg/10a 사용 시 각각 20%, 42%, 60% 증수되었고, 성분함량 중 rutin은 질소 추비 사용량이 많을수록 증가되는 경향이었으며, quercitrin은 질소 추비 3kg/10a 시용에서 다소 높았다.

• 한국약용작물학회지
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• 제16권3호
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• pp.139-143
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• 2008

The antioxidant activities of Agrimony (Agrimonia pilosa L.) and Chinese lizardtail (Saururus chinensis Baill) according to extraction methods were measured. SOD-like activity showed greater antioxidant effects with ethanol solvent than those with water. Ethanol extracts of Agrimony leaves showed the highest SOD-like activity of 94.4%. SOD-like activity differed according to the extraction solvents. The contents of polyphenolic compounds were higher in water extracts than those in ethanol extracts. The contents were 161.4 mg for Agrimony roots, 100.2 mg for Agrimony leaves, and 79.1 mg for Agrimony stalks in order. EDA in Agrimony leaves that were highest among medicinal plants were 83.4% in the water extract and 81.7% in the ethanol extract. The anticancer effects of the extracts by water and ethanol from Agrimony and Chinese lizardtail were experimented. The growth of stomach cancer cells, SNU-719 was inhibited 94.5% by the hexane fractions of Agrimony and also the growth of liver cancer cells, Hep3B was inhibited 83.2% by the hexane fractions of Agrimony, while the growth of normal cell, DC2.4 was not affected.

• 대한본초학회지
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• 제33권3호
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• pp.11-18
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• 2018

Objectives : Saururus chinensis and Houttuynia cordata (Saururaceae) are perennial herbs using for medicinal purposes in Korea. The objectives of this study are to compare anatomical key characters between two medicinal plants and to provide fundamental information for the identification of two herbal medicines by using anatomical features. Methods : Cross-sections of root, rhizome, stem, petiole, and leaf for each species were observed in this study. Materials were analyzed through dehydration, paraffin embedding and micro-sectioning, and double staining with Safranin O and Fast-Green FCF. Observations of permanent preparation were conducted using light microscope. Results : S. chinensis and H. cordata were distinguished with anatomical differentiations; Idioblasts with essential oil were scattered in the parenchyma cell of cortex, pith, and phloem of S. chinensis, on the other hand, in H. cordata, idioblasts were distributed ring-shaped in the cortex of the root. S. chinensis had two cycles of vascular bundles in the stem while H. cordata had one cycle. Hypodermis layer was conspicuous in a stem of H. cordata, crystals were observed the only parenchyma in a stem of S. chinensis, and epidermal oil cells were developed in the epidermis of H. cordata. S. chinensis had air cavity at the cortex and pith of the stem. The shape of cross-section was polygonal in the stem of S. chinensis and was circular in the stem of H. cordata. Conclusions : We investigated anatomical study of Korean S. chinensis and H. cordata. To identify two herbal medicines, we considered main anatomical features and provided identification key here.

• 대한의생명과학회지
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• 제25권4호
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• pp.339-347
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• 2019

Saururus chinensis (SC) belongs to the dicotyledonous plants, and its roots, leaves and flowers are white, so it is named three hundred and seconds. It is mainly distributed in Korea, China and Japan. In Korea, it is a native plant distributed in Jejudo and Jirisan areas. It has been known to improve blood circulation, anticarcinogenic effects and purge. However, studies of the efficacy on digestive system is few. This study was conducted to evaluate the effects of oral administered-SC extract in loperimide-induced constipation rats. The amount, weight and water content of the stools were measured. The number and type of stools in the large intestines were measured, and the amount of intestinal mucus was analyzed by serological analysis and histologic special staining. The severity of constipation in SC groups was significantly less than that in control group (non-SC rats). Digital Image processing also showed weaker inflammation on the large intestines of SC groups than that of control group (non-SC group). Especially, with increased dose dependent manner of SC extract, the amount and integrity of intestinal mucus increased. These results suggest that SC extract may prevent the symptoms of constipation.

• 한국작물학회지
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• 제47권3호
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• pp.157-160
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• 2002

삼백초의 근경 수확방법을 인력수확에서 생력기계화 수확기술로 개선코자 트랙터부착 굴취기 등 4종의 수확기기의 기계수확 효율을 비교, 검토하였던 바 그 결과를 요약하면 다음과 같다. 1. 총생력시간은 인력에 비하여 경운기 경운 60%, 경운기부착 굴취기 64%, 트랙터부착 굴취기 67%절감되었다. 2. 근경의 손실율은 인력수확 13.9%, 경운기 경운 11.7%, 경운기부착 굴취기 9.8%, 트랙터부착 굴취기 5.1%로 기계수확에서 낮았다. 3. 상품 근경수량은 인력수확 3,032 kg/10a에 비하여 경운기 경운은 248 kg 감소하였으나, 경운기부착 굴취기와 트랙터부착 굴취기는 56kg, 320kg각각 증가되었으며, 총 근경수량은 인력수확에 비하여 기계수확에서 3-10%증가되었는데, 트랙터부착 굴취기는 10%의 증가로 가장 높은 수량을 보였다. 4. 경제성은 인력수확에 비하여 기계수확에서 13-27%높았으며, 트랙터 부착 굴취기는 27%로 가장 높았다. 5. 트랙터부착 굴취기는 생력효율, 상품수량, 총 근경수량 그리고 경제성에서 가장 높거나, 많은 것으로 나타나 적용가능성이 가장 높은 것으로 나타났다.

• Toxicological Research
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• 제18권2호
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• pp.117-127
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• 2002

Saururus chinensis Baill has been used in Korean folk medicine for the treatment of various diseases such as edema, Jaundice, and furuncle. The components of this plant were extracted into four fraction. Among the four fraction, hexane and ethyl acetate fraction were highly toxic to 3T3 mouse embryo fibroblast and Raw 264.7 mouse macrophage, but n-butanol and residue fraction did not show any toxic effect to those cell lines. n-Butanol and residue fraction exhibited antioxidant effects on hydro-gen peroxide, hydroxyl radical, and superoxide anion directly in vitro and in the 3T3 fibroblasts. All the four fractions inhibited lipid peroxidation measured by thiobarbituric acid reactive substances (TBARS) formation. In addition, n-butanol and residue fraction showed inhibitory effects on lipopolysaccharide (LPS)-induced nitric oxide production, and also down-regulated inducible nitric oxide synthase (iNOS) mRNA transcription 6 h after LPS stimulation in Raw 204.7 cells. Only n-butanol fraction, which mainly consists of flavonoids, inhibited NF-kB activation by decreasing IkBa degradation 90 min after LPS stimulation. horn the results, it is suggested that this plant could be a good candidate material for drug development based on its antioxidant and/or anti-inflammatory constituents.

• 한국약용작물학회지
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• 제14권3호
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• pp.143-147
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• 2006

삼백초(三白草) 재배에 있어서 토성에 따른 생육과 유효성분을 분석하여 안정적인 재배법을 확립하고 고품질 삼백초를 생산하고자 시험을 수행한 결과를 요약하면 다음과 같다. 가. 삼백초의 절수와 엽수, 분지수는 토성 간 차이가 없었으며, 주당 줄기와 잎의 무게는 사양토가 가장 많고, 양토, 식양토, 사토의 순으로 무거웠다. 직경 5mm이하 뿌리는 토성 간차이가 없었으나, $5.1{\sim}10.9\;mm$의 굵기는 사양토, 양토 그리고 식양토에서 $437{\sim}465\;g$로 차이가 없었고, 11 mm이상은 식양토가 많았다. 건물율은 $19.1{\sim}20.8%$로 차이가 없었다. 나. 잎의 quercetin-glycoside 함량은 양토와 사양토에서 $219.3{\sim}222.4\;mg/100\;g$로 가장 높았으며, quercitrin>rutin>isoquercitrin>hyperin의 순으로 높았다. 줄기는 사토와 사양토가 각각 14.8 mg/100 g과 12.4 mg/100 g로 가장 많았으며, quercetin-glycoside 중 rutin이 가장 높았다. 다. 뿌리의 lignans 함량은 식양토, 양토, 사앙토, 사토의 순으로 높은 경향이었으며, lignans 관련 물질 중 manassatin B가 가장 많았다.