• The Journal of Korean Medicine
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• v.28 no.1 s.69
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• pp.51-62
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• 2007

Objectives . The types of Sasang constitutional medicine (SCM) have definite effect on response to herbal drugs. The majority of human P45O dependent xenobiotic metabolism is carried out by polymorphic enzymes which can cause abolished, altered or enhanced metabolism. Therefore, we evaluated the relation of major CYP2C19, 2D6 polymorphism with Sasang types. Methods : 214 healthy subjects were recruited with informed consent; 172 among them had Sasang diagnosis by QSCC2. CYP2D6, 2C19 polymorphism were determined by PCR-RFLP method. Results : None of the Sasang types showed significant difference in CYP2D6, 2C19 polymorphism. However, the Tae-um type showed relatively low frequency of CYP2D6 $^{*}$10/$^{*}$10 polymorphisms with low activity (p=0.110). In the So-yang type, specific $^{*}$3/$^{*}$3 genotype which is a poor metabolizer of CYP2C19$^{*}$3 was detected (p=0.078).Conclusion . These results suggest that the Tae-um type which is said to have high liver function in SCM has the tendency of high drug-metabolizing enzyme activity. With further study, the CYP polymorphism could serve as a scientific tool for SCM diagnosis.

• Journal of Sasang Constitutional Medicine
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• v.21 no.1
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• pp.79-84
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• 2009

1. Objectives This study was proposed to use the test-retest method to verify the independence and agreement between the questions (Short Form Sasang Classification Questionnaire for American ; SF_SSCQ-A). 2. Methods The questionnaire was administered to 50 American and they were asked to complete the questionnaire again two weeks after the first administration. The final subjects are 42 except of 5 dropouts and 3 insufficient respondents. A reliability analysis for each individual question was conducted using the test-retest method to verify the independence and agreement between the questions. To verify independence, a Chi-square test with crosstabs analysis and p-values was used. The agreement verification was conducted by using the Cohen kappa coefficient. In addition, the constitutional variable was defined as the constitutional attribute of each question, and Pearson's correlation coefficient was confirmed after testing the scale. 3. Results and Conclusions The test-retest method showed that Pearson's correlation coefficients for the results of the two tests ranged from 0.66 to 0.87. The Chi-square test results indicated that there are 7 independent item. Among the other 114 questions, the agreement test revealed that 88 questions (70.5%) showed above common agreement.

• Journal of Sasang Constitutional Medicine
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• v.18 no.2
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• pp.34-40
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• 2006

1. Objectives We are going to develope 3D Face Recognition Apparatus to analyse the facial characteristics of the Sasangin. In the process, we should identify the recognition rate of the three dimensional position using this Apparatus. 2. Methods We took a photograph of calibrator($280{\times}400mm$) with interval of 20mm longitudinal direction of 10 times using 3D Face Recognition Apparatus. In the practice, we obtained 967 point to the exclusion of points deviating from the visual field of dual camera. And we made a comparison between measurement values and three dimensional standard values to calculate the errors. 3. Results and Conclusions In this test, the average error rate of X axis values was 0.019% and the maximum error rate of X axis values was 0.033%, the average error rate of Y axis values was 0.025% and the maximum error rate of Y axis values was 0.044%, the average error rate of Z axis values was 0.158% and the maximum error rate of Z axis values was 0.269%. This results exhibit much improvement upon the average error rate 1% and the maximum error rate 2.242% of the existing 3D Recognition Apparatus. In conclusion, we assessed that this apparatus was adaptable to abstract the facial characteristic point from three dimensional face shape in the mechanical aspects.

• Journal of Sasang Constitutional Medicine
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• v.20 no.1
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• pp.34-41
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• 2008

1. Objectives We had been developing a 3D Automatic Face Recognition Apparatus (3D-AFRA) in order to evaluate the external appearances with more objectivity. This apparatus provides a 3D image and numerical data on facial configuration, and this study aims to evaluate the accuracy of 3D-AFRA recognition. 2. Methods Each scanned pictures were pointed with the 3D Automatic Face Recognition Apparatus(3D-AFRA). And the results were compared with data pointed pictures with manual. And we analysed the difference between Automatic and manual by paired -test. 3. Results and conclusions In frontal face, the P-value was more than 0.05. In conclusion, We assessed that accuracy of recognition of 3D Automatic Face Recognition Apparatus(3D-AFRA) is considerably good. But we should develop methods of measurement for lateral face and indistinct points of frontal face.

• Journal of Sasang Constitutional Medicine
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• v.18 no.3
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• pp.49-56
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• 2006

1. Objectives We are going to develope 3D Face Recognition Apparatus to analyse the facial characteristics of the Sasangin. In the process, we should identify a Hardware Error Analysis of this Apparatus. 2. Methods We verified The resolution, the repetition ability, the Flatness and the Cylindericity of 3D Face Recognition Apparatus by measuring a triangular pyramid, an exact square pillar and a cylinder. 3. Results and Conclusions In this test, The resolution of 3D-FARA was $0.0368mm{\times}0.0594mm{\times}0.2748mm(X{\times}Y{\times}Z)$, the repetition ability was 0.1187mm, the Flatness was 0.17188mm. the Flatness of triangular pyramid was 1.39034mm and the Cylindericity of cylinder was 3.1306mm. In conclusion, If we use 3D-FARA, It is necessary to complement the site of top of the nose and the outline of face, which is likely to occur hardware error, by using software invention or attaching the Land mark to subject.

• Journal of Sasang Constitutional Medicine
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• v.20 no.1
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• pp.67-88
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• 2008

1. Objectives The aim of this study was to find out clinical characteristics of atopic dermatitis according to Sasang Constitutions and to help on Sasang Constitutional management and treatment of atopic dermatitis 2. Methods 108patients with atopic dermatitis were involved in the study. The patients had visited C Oriental Clinic from January 2007 to September 2007 and had taken oriental herbal medicine for over one month. They were divided into four groups by Sasang Constitutions and were evaluated the clinical features of atopic dermatitis according to Sasang Constitutions. 3. Results and Conclusions The clinical characteristics for 108 patients with atopic dermatitis was surveyed 1. Soyangin with atopic dermatitis had significantly more Allergic conjunctivitis than other Constitutions, and Taeumin with atopic dermatitis had significantly less Allergic conjunctivitis than other Constitutions. 2. Soyangin with atopic dermatitis had significantly more 'Sleep loss' than other Constitutions. 3. Emotion was significantly more aggravating factor of atopic dermatitis in Soyangin than in other Constitutions. 4. Soeumin with atopic dermatitis had significantly more 'Orbital darkening' than other Constitution. 5. 'Tuna' was significantly more aggravating factor of atopic dermatitis in Soeumin than in other Constitution. The treatment progress for 57 patients with atopic dermatitis was surveyed 6. Soyangin with atopic dermatitis had significantly more improvement than other Constitution and Soeumin with atopic dermatitis had significantly less improvement than other Constitution in Sasang Constitutional Medicine treatment.

• Journal of Sasang Constitutional Medicine
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• v.17 no.1
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• pp.16-24
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• 2005

1. Objectives This study is purposed to find a dietary treatment of Taeyangin in the ${\ulcorner}$Sik Ryo Chan yo(食療纂要)${\lrcorner}$(1460). 2. Methods It was researched as bibliographic study with ${\ulcorner}$Sik Ryo Chan YO${\lrcorner}$ of the oldest Korean book concerned about a dietary treatment and ${\ulcorner}$Hyangyakjipseongbang(鄕藥集成方)${\lrcorner}$ ${\ulcorner}$Euibangyoochui(醫方類聚 )${\ulcorner}$ etc. 3. Results and Conclusions (1) ${\ulcorner}$Hae Dong Moon Hun Chong Rok(海東文獻總錄)${\lrcorner}$ misquoted ‘Five Vegetable(五菜)’ written in ${\ulcorner}$Sik Ryo Chan YO${\lrcorner}$ as 'One leaf(一葉)'. (2) The efficacy of persimmon, Mo Gwa, Oh Ga Pi(the root bark of various araliaceous shrubs), Crucian, Ju Du Kang, Watershied plant(Brassenia purpurea) in this book are the same or similar to those of ${\ulcorner}$Dongyi Suse Bowon${\lrcorner}$ and ${\ulcorner}$Dongmu Yugo${\lrcorner}$. But some of them are represented as having different properities in Sasang Constitutional Medicine(SCM) and ${\ulcorner}$Sik Ryo Chan YO${\lrcorner}$. For example, dried persimmon is used for the treatment of deafness, Crucian for asthma and Song Jul(松節) for bruises in ${\ulcorner}$Sik Ryo Chan Yo${\lrcorner}$ but SCM. (3) This book doesn`t have a definite expression about Sasangin, but it contains documents of clinical cases. So it seems that this book would somewhat affect to SCM after ages.

• The Journal of Korean Oriental Chronic Disease
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• v.10 no.1
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• pp.39-45
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• 2005

Objectives It is the case study of a critically ill patient with cerebral infarction and acute edematous change at femur due to a hematoma, of whom taken care with herb medicine according to the diagnosis of SCM(Sasang Constitutional Medicine). Methods The syndrome of the patient was diagnosed as a superficial disease of Taeumin. So after the on-set of the femoral edema, Jowiseungchung-tang added Castanea mollissima(Gunyul) and Maladera castanea(Jejo) was used. And we checked the change of the circumferencial size her thigh and followed up the sonography. Results and conclusions The therapy was significantly effective, and the edema was rapidly absorbed. The circumferential size was 83cm at on-set time, but got smaller to 57cm almost same to the healthy side of her thigh, and there was no more hematoma or systemic hemorrhagic sign on the body.

• Journal of Sasang Constitutional Medicine
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• v.21 no.2
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• pp.123-136
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• 2009

1. Objectives : This study is a pilot study to construct of metabolic syndrome model with constitutional type. We focused on the correlation of Metabolic syndrome(MetS) and ordinary symptoms with Taeumin at 40. 2. Methods : 32 subjects who had taken health examinations and diagnosis of Sasang constitution from Oct 1, 2008 to Dec 31, 2008 at Kyung-Hee medical center were included and underwent B-mode ultrasonography for measurement of intima-media thickness of common carotid arteries. MetS was defined by the criteria of the criteria of the National Cholesterol Education Program Adult Treatment Panel III. 3. Results and Conclusions : Mean intima-media thickness of common carotid artery was higher in subjects with MetS compared with control subjects(0.56$\pm$0.12 vs 0.54$\pm$0.08mm) however. The ordinary symptoms shown to differentiate the MetS group and the control group were related to "dark urine color," "dryness of eyes," and "night sweat". Therefore, these ordinary symptoms can be said to be indicators of the Taeumin with Mets syndrome.

• The Journal of Korean Medicine
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• v.35 no.2
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• pp.60-68
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• 2014

Background: Pattern identification is a unique diagnostic method of traditional Oriental medicine that has recently been the target of questionnaire-based research. Sasang (four-types) constitutional medicine (SCM) is a practice in traditional Korean medicine that seeks to promote objectivity in diagnostics. This paper attempts to illuminate the relationship between constitutions and the pathogenic factors of pattern identification through questionnaires completed by menopausal women about their symptoms. Methods: From March to October 2012, we examined 291 women from the general population, with ages ranging from 40 to 60 years, applying the Kupperman index, the Menopause-Specific Quality of Life Questionnaire (MENQOL), pattern identification based on the Diagnosis System of Oriental Medicine (DSOM), and SCM. We then analyzed the relationship between constitutional type and pathogenic factors. Results: No significant differences were found in the scores of either the Kupperman index or MENQOL questionnaire in relation to constitutional type. However, in a statistical analysis correlating the DSOM pathogenic factor scores (PFS) with the scores of the Kupperman index and MENQOL vasomotor subscale, heat showed a significant positive correlation with SoYang type (SY) and TaeEum type (TE), but not SoEum type (SE), while insufficiency of yin and insufficiency of yang, as well as blood deficiency, showed a significant positive correlation with the TE and SE types. Conclusion: The pathogenic factors in the menopausal symptoms of middle-aged women, specifically the prominent menopausal symptom of facial flushing, differed significantly according to constitutional type.