• Journal of the Korea institute for structural maintenance and inspection
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• v.13 no.3 s.55
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• pp.197-208
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• 2009

The purpose of this research is the evaluation of the estimation equation of "CEP-FIP Model Code 1990(1991)", recently included in the domestic "Concrete Structure Design Code(2007)" in consideration of the concrete strength. As evaluation tools, crack element model applied a detailed bond-slip model as well as crack width obtained from experimental results by earlier researches. The crack element model is verified through the comparison with experimental results. The important variables in the estimation equation for the crack width in CEP-FIP Model Code 1990 are the tension stiffening effect and mean bond stress proposed in the paper to be improved in consideration of the concrete strength.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.28 no.3
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• pp.254-261
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• 2006

Moderate to severe dentofacial deformities usually require combined orthodontic treatment and orthognathic surgery to obtain the most stable result with optimal function and facial esthetics. Accordingly, the orthodontist and oral maxillofacial surgeon must be able to exactly diagnose existing deformities, establish an appropriate treatment plan, and execute the recommended treatment. Especially, to obtain optimal result of the maxillary surgery, model surgery is essential. But, the preoperatively planned position of the maxillary dental arch often cannot be sufficiently achieved during actual surgery, and deviations in the sagittal and vertical dimensions are common. To achieve three dimensional repositioning of the maxilla exactly, several methods have been introduced so far. Recently Model Repositioning Instrument (MRI, SAM, Inc., $M\ddot{u}nchen$, Germany), one of these methods, has been introduced and applied clinically, which is reported as accurate, effective and prompt method for three dimensional repositioning of the maxilla. This article describes an introduction and a clinical application of this MRI.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.11
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• pp.1856-1863
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• 2003

Overlay model had several advantages to describe hysteretic behavior of material and showed good capability for many engineering materials. However, this model is only applicable to material obeying Masing postulate. Some materials such as 316L stainless steel do not follow Masing postulate and show cyclic hardening(or softening) and strain range dependence. Low cycle fatigue tests of 316L stainless steel at 600$^{\circ}C$ were performed to investigate the characteristics of cyclic behavior of non-Masing material. From all tests cyclic softening was observed. There were differences in elastic limit of hysteresis loop according to applied strain range. To consider these features, modified overlay model was developed. Yield stresses of subelements were divided into isotropic and anisotropic part to describe the non-Masing behavior. The plastic strain range memorization was introduced to consider the strain range dependence. The prediction using modified overlay model showed a good accordance to actual hysteresis loops.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.4
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• pp.124-131
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• 2007

The numerical study on behavior of impinging spray from high-pressure swirl injector under various ambient temperatures was performed by using spray vaporization model and spray-wall impingement model implemented in modified KIVA code, and these spray models were estimated by comparison with experimental results. To compute the spray-wall impingement process, the Gosman model, which is based on the droplet behavior after impingement determined by experimental correlations, was used. The modified Abramzon and Sirignano model, that includes the effects of variable thermodynamic properties and non-unitary Lewis number in the gas film, was adapted for spray vaporization process. The exciplex fluorescence measurements were also conducted for comparison. The experimental and numerical analysis were carried out at the ambient pressures of 0.1 MPa and at the ambient temperature of 293 K and 473 K, and the spray characteristics, such as spray-wall impingement process, gas velocity field, SMD and vapor concentration, were acquired. It was found that the impinging spray develops active and SMD is small at vaporization conditions.

• Journal of the Korean Solar Energy Society
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• v.39 no.4
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• pp.11-24
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• 2019

The total solar irradiation on horizontal surfaces is separated into the beam and diffuses components. Although horizontal global irradiance is a commonly measured parameter for many sites, horizontal diffuse irradiance is not so readily obtainable. For such sites that measure global irradiation alone, a simple but reasonably accurate method is required to estimate diffuse irradiance from its global counterpart. This study investigates the applicability of correlation coefficients models correlating hourly diffuse and beam fraction and hourly clearness index in Daejeon. The three diffuse to global correlation coefficients models (Orgill and Holland model, CIBSE Guide J model, and Erbs et al. model) are selected and the three modified beam to global correlation coefficients models are generated. MBE, RMSE, r-squared of Daejeon and Daejeon boundary site-fitted models are compared with the case of original coefficients. The comparison result shows that the beam and diffuse to global solar irradiation correlation coefficients models with boundary site-fitted coefficients are best suitable for Daejeon. Further researches will be conducted to find the boundary site-fitting method using measured data of other cities and correlation coefficients models using solar altitude, cloud cover, and sunshine duration.

• Journal of Pharmaceutical Investigation
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• v.35 no.4
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• pp.279-285
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• 2005

Ground CS-891 (N-[1-(4-methoxyphenyl)-1-methylethyl]-3-oxo-4-aza-5a-androst-1-ene-$17{\beta}$-carboxamide) of poorly water soluble drug was obtained using a Heiko Seisakusho model TI-100 vibration mill, and samples with different crystallinity were prepared at mixture ratios of 10:0, 7:3, 5:5, 3:7 and 0:10 (intact;ground CS-891). Physicochemical characterizations were obtained using qualitative and quantitative X-ray diffractometry, different scanning calorimetry (DSC), scanning electron microscopy (SEM), Quantasorb surface area analyzer, and controlled atmosphere microbalance. With increase of amorphous CS-891 in mixture ratios, the intensities of X-ray diffraction peaks of crystalline CS-891 were decreased, whereas surface area, water absorption, and exothermic peaks in DSC were increased. The apparent solubility of ground CS-891 was $4.4\;{\mu}g/ml$ and the solubility of intact CS-891 was $3.1\;{\mu}g/ml$ at $37{\pm}1^{\circ}C$. The apparent precipitation rates of CS-891 in a supersaturated solution during the solubility test were increased with an increase of amorphous CS-891, and a crystalline form of CS-891 transformed from amorphous CS-891 after the solubility test was found by X-ray diffraction analysis, DSC and SEM. The dissolution profiles of CS-891 with different crystallinity at $37{\pm}1^{\circ}C$ by the USP paddle method were investigated, and the apparent dissolution rate constant of ground CS-891 was about 5.9-fold higher than that of intact CS-891. A linear relationships between the crystallinity of CS-891 and the apparent dissolution rate constant (r>0.96) were obtained.

• Bulletin of the Korean Chemical Society
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• v.26 no.11
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• pp.1695-1700
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• 2005

Catechol-O-methyltransferase (COMT, EC 2.1.1.6) is an S-adenosylmethionine (SAM, AdoMet) dependent methyltransferase, and is related to the functions of the neurotransmitters in various mental processes, such as Parkinson’s disease. COMT inhibitors represent a new class of antiparkinson drugs, when they are coadministered with levodopa. Based on x-ray structure of rat COMT (rCOMT), the three dimensional structure of human COMT (hCOMT) was constructed by comparative homology modeling using MODELLER. The catalytic site of these two proteins showed subtle differences, but these differences are important to determine the characterization of COMT inhibitor. Ligand docking study is carried out for complex of hCOMT and COMT inhibitors using AutoDock. Among fifteen inhibitors chosen from world patent, nine models were energetically favorable. The average value of heavy atomic RMSD was 1.5 $\AA$. Analysis of ligand-protein binding model implies that Arg201 on hCOMT plays important roles in the interactions with COMT inhibitors. This study may give insight to develop new ways of antiparkinson drug.

• Bulletin of the Korean Chemical Society
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• v.27 no.3
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• pp.381-385
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• 2006

The temperature dependence on the electron transfer rate constant $(k_{app})$ for hydroquinone redox center in $H_2Q(CH_2)_n$SH-SAMs (n = 1, 4, 6, 8, 10, and 12) on gold electrode was investigated to obtain reorganization energy $(\lambda)$ using Laviron’s formalism and Arrhenius plot of ln $[k_{app}/T^{1/2}]$ vs. T^{-1} based on the Marcus densityof-states model. All the symmetry factors measured for the SAMs were relatively close to unity and rarely varied to temperature change as expected. The electron tunneling constant $(\beta)$ determined from the dependence of the $k_{app}$ on the distance between the redox center and the electrode surface gives almost the same $\beta$ values which are quite insensitive to temperature change. Good linear relationship of Arrhenius plot for all $H_2Q(CH_2)_n$SH-SAMs on gold electrode was obtained in the temperature range from 273 to 328 K. The slopes n Arrhenius plot deduced that $\lambda$ of hydroquinone moiety is ca. 1.3-1.4 eV irrespectively of alkyl chain length of the electroactive SAM.

• The Transactions of the Korea Information Processing Society
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• v.5 no.10
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• pp.2584-2590
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• 1998

In the existing fuzzy aggregation method, the operators such as t-norm, t conorm, mean operator, Yafer's operator and $\gamma$ operator are used to aggregate the values of membership functions. However, these methods have problems in that they do not reflect the decision situation properlyin the decision process. In order to solve these problems we suggest a situation assessment model(SAM) to reflect the decision situation in the decision proess. In the fuzzy decision environment, we propose a new aggregation method to reflect the decision situation using the result of SAM. We call it the aggregation based on situation assessment (ASA) method. It makes the stepwise aggregation with derection according to the decision situation. Moreover, we compare ASA method with the existing aggregation methods.

• Journal of Korea Society of Digital Industry and Information Management
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• v.13 no.3
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• pp.19-25
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• 2017

Nowadays, networked computer systems play an increasingly important role in our society and its economy. They have become the targets of a wide array of malicious attacks that invariably turn into actual intrusions. This is the reason computer security has become an essential concern for network administrators. Recently, a number of Detection/Prevention System schemes have been proposed based on various technologies. However, the techniques, which have been applied in many systems, are useful only for the existing patterns of intrusion. Therefore, probe detection has become a major security protection technology to detection potential attacks. Probe detection needs to take into account a variety of factors ant the relationship between the various factors to reduce false negative & positive error. It is necessary to develop new technology of probe detection that can find new pattern of probe. In this paper, we propose an hybrid probe detection using Fuzzy Cognitive Map(FCM) and Self Adaptive Module(SAM) in dynamic environment such as Cloud and IoT. Also, in order to verify the proposed method, experiments about measuring detection rate in dynamic environments and possibility of countermeasure against intrusion were performed. From experimental results, decrease of false detection and the possibilities of countermeasures against intrusions were confirmed.