• 대한예방의학회:학술대회논문집
• /
• 대한예방의학회 2004년도 제56차 추계 학술대회 연제집
• /
• pp.34.2-35
• /
• 2004

• 한국동물위생학회지
• /
• 제38권2호
• /
• pp.71-75
• /
• 2015

Porcine salmonellosis is an economically important disease affecting the global pig industry today. Salmonella (S.) Typhimurium is highly contagious and may rapidly spread within pig populations of herd. To investigate the prevalence of porcine salmonellosis in Jeju, a total of 12,885 blood sera of 96 pig farms from 2009 to 2012 were analyzed by microplate agglutination test. Antibodies to S. Typhimurium were detected in all of pig farms tested in Jeju Province, and the mean of seropositive rate of individual pig was 18.8%. The mean seropositive rate of S. Typhimurium in sows (46.7%) was 7 times higher than that of weaned or growing pigs (6.7%). The lowest seropositive rate (3.0%) was detected in 40 day-old pigs, and this result might be closely associated with the marked decrease of maternal passive immunity. The seropositive rate in winter (42.7%) was higher than in other seasons.

• 한국동물위생학회지
• /
• 제41권3호
• /
• pp.133-139
• /
• 2018

Porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) are known as significant immunosuppressive viruses in pigs. In this study, we investigated the correlation of PCV2 and PRRSV in enteric lesions of porcine salmonellosis. A total of 64 cases were classified into four pig groups as group A (24 cases, S. Typhimurium), group B (11 cases, S. Typhimurium+PCV2), group C (16 cases, S. Typhimurium+PRRSV) and group D (13 cases, S. Typhimurium+PCV2+PRRSV). Comparing with group A, ulcerative enteritis in large intestine was little more prevalent in the PCV2 infected pigs in group B and D. And lymphoid depletion in gut-associated lymphatic tissue (GALT) of large intestine was also detected in PCV2 positive group B (36.4%) and D (30.8%). According to the results of immunohistochemistry (IHC), PCV2 antigens (83.3%) were more prevalently distributed in the intestinal lesions of porcine salmonellosis than PRRSV antigens (10.3%). PCV2 were also detected in the lymphoid depleted GALT of the large intestine from 7 of the 8 pigs (87.5%), but PRRSV were not found in all cases. It may explain that PCV2 can play a certain immunological role to enhance secondary bacterial infection in porcine alimentary tracts.

• 농촌의학ㆍ지역보건
• /
• 제17권2호
• /
• pp.123-127
• /
• 1992

Of 80 cases of Salmonellosis reported in a provincial area in 1992, 90% were related to outbreaks, which occurred from Apr. to Nov. And the serotypes include the following: typhimurium, hadar, and enteritidis etc. Among these outbreaks the authors carried out the epidemiological investigation for 'I-eup'(highest attack region) outbreak. The results obtained were as follows: 1. The S. typhimurium isolated from stools of 7 cases among 29 cases. 2. The common-source of exposure was boiled pork and/or skewered slices of seasoned meat. 3. The incidence rate was 65.1%(29 cases). 4. The incidence showed significant difference between males(32.1%) and females(80.0%). 5. The incidence in under 20 years of age and 40 years of age were much higher than other age groups but there was no significant difference among much age groups. 6. The mean and the median incubation period were 18.5 and 17.0 hours respectively. 7. The secondary attack was not appeared.

• Journal of Dairy Science and Biotechnology
• /
• 제38권4호
• /
• pp.169-188
• /
• 2020

Salmonella spp. is the most common cause of gastrointestinal food poisoning worldwide, and human salmonellosis is mostly caused by the consumption of contaminated food. Therefore, the development of rapid detection methods for Salmoenlla spp. and rapid identification of the source of infection by subtyping are important for the surveillance and monitoring of food-borne salmonellosis. Therefore, this review introduces (1) History and nomenclature of Salmoenlla spp., (2) Epidemiology of Salmoenlla spp., (3) Detection methods for Salmoenlla spp. - conventional culture method, genetic detection method, molecular detection methods, and aptamer, and (4) Subtyping methods for Salmoenlla spp. - pulsed-field gel electrophoresis and repetitive sequence-based polymerase chain reaction (PCR).

• 한국환경농학회지
• /
• 제27권2호
• /
• pp.156-162
• /
• 2008

항생제의 오남용으로 인한 항생제 내성을 가진 세균의 출현은 공중보건학적인 측면에서 많은 피해를 입히고 있다. 또한, 세포 내 기생세균의 경우 예방과 치료가 어려운 상황에 놓여져 있고 항생제 대체 물질개발에 많은 관심이 집중되고 있다. 어성초는 오랜 기간 동안 소독제, 이뇨제, 해열제, 항균제, 항바이러스 제제, 항염증 제제로서 사용되어왔으며 중요한 민간요법의 하나로서 인식되고 있는 바, 본 실험에서는 어성초의 ethanol 추출물이 세포내 기생 난치성 세균 감염증인 S. typhimurium의 감염증에 대한 치료효과를 검증하였다. 본 실험의 결과로서 HCEE 추출물이 탐식세포의 형태적 변화를 유도하였고, S. typhimurium에 대한 직접적인 살균작용과 탐식세포를 통한 항균작용은 미약한 것으로 나타났다. 또한 HCEE 추출물이 S. typhimurium의 탐식세포 감염 시 시간경과에 따라 감염능 및 세포내 증식능이 감소하는 것이 확인되었다. 탐식균에 의한 사멸을 유도하는 탐식세포의 NO의 산생량에 있어서는 HCEE 추출물의 처리가 탐식세포로부터 NO 산생이 감소되어 NO를 이용한 탐식세포의 균 사멸과는 직접적 연관이 없을 것으로 추정되며, 마우스 감염시험에서 HCEE를 투약이 상당한 치료효과를 나타내어 HCEE가 S. typhimurium에 의한 염증을 감소시키고, 또한 apoptosis를 유도함으로 인해 균을 제거함으로 이루어지는 것으로 추측된다. 본 연구를 통해 HCEE의 살모넬라증에 대한 치료효과를 확인 할 수 있었으며, 천연소재 약용자원을 활용한 난치성 세균 감염증에 대한 신약개발이 가능하고, 이의 활용은 항생제 오남용을 줄일 수 있고 국민보건 증진에 이바지 할 것이다.

• Pediatric Infection and Vaccine
• /
• 제20권1호
• /
• pp.1-8
• /
• 2013

목적 : 장티푸스와 세균성 위장염의 주된 원인인 살모넬라균에 의한 감염증은 우리 주변에서 흔하게 관찰할 수 있는 질환이며 최근 장티푸스의 발생 수는 줄고 있으나 살모넬라 감염증은 꾸준히 보고되고 있다. 이에 본 연구에서는 최근 12년간 살모넬라증 환자의 임상적 양상과 배지에서 동정된 살모넬라 균주의 변화, 항생제 내성을 연구하기로 하였다. 방법 : 2000년 1월부터 2011년 12월까지 12년간 분당 차병원에 입원한 18세 이하의 환아를 대상으로 하였으며, 대상자의 일반적인 특성을 의무기록을 통하여 후향적으로 조사하여 환아의 임상양상을 비교 분석하였다. 결과 : 대상 환아 수는 총 53례였으며 환아의 연령별 분포를 보면 2세가 10례로 가장 많은 분포를 보였으며 중간값은 3세(최소 12일, 최대 18세)였다. 대상 환아 중 남아의 수는 33례(62.3%)이다. 계절별로는 여름(6,7,8월)이 21례(39%)로 가장 많은 빈도를 보였으며, 연도별로 비교하였을 경우 2001년이 11례로 가장 많았으며, 2003년에는 7례가 진단되었으나 2004년에는 2례로 급감하는 양상을 보였으며 2009년과 2010년에는 진단된 환아가 없었다. S. typhi가 배양된 환아는 모두 3명이었으며 모두 혈액에서 S. typhi가 배양된 균혈증을 보이고 있었다. 항생제에 대한 감수성 결과에서는 ampicillin에 대한 내성이 16례로 가장 높았으며 S. typhi는 항생제 감수성 결과 내성을 보이는 항생제가 없었다. 2000년 1월부터 2005년 12월까지와 2006년 1월부터 2011년 12월까지의 두 군으로 나누어 전 6년군과 후 6년군으로 나누었으며, 전 6년군의 환아는 40례였으며 후 6년군의 환아는 13례였다. 연도에 따른 ampicillin에 대한 내성율은 후 6년군에서 더 증가한 소견을 보이고 있으나 통계학적인 의미는 없었으며(25% vs. 38.5%, P=0.349) 연도에 따른 혈청군별 항생제 내성율의 분포상 전 6년군에서는 D군이 가장 많았고, 후 6년군에서는 C군과 D군이 많았다. 결론 : 본 연구 결과 살모넬라 감염증은 2000년대 초반에 많았으나 2004년부터 급감하는 소견을 보이고 있으며 연도별로 본 혈청형과 항생제 내성의 경향에는 뚜렷한 변화가 관찰되지 않았다.

• 대한수의학회지
• /
• 제40권1호
• /
• pp.173-186
• /
• 2000

This experiment was carried out to investigate the tendency of incident diseases in pre- and post- weaning piglets which ages were 1 to 7 weeks old by laboratory diagnosis and in order to minimize death in preweaning piglets and of stunted growth in postweaning piglets. The result of this experiment used as the basic data for the preventive programs in pre- and post- weaning piglets and were as follows: 23 different diseases diagnosed in 331 cases were studied in relation to age, season, and etiology. The most prevelent diseases of pre- and post- weaning piglet were Colibacillosis(79 case, 23.9%) and the major diseases were Salmonellosis(44 cases, 13.3%), Anemia(37 cases, 11.2%). Unknown viral disease(20 case, 6.1%), Rota viral infection(19 case, 5.8%), Porcine reproductive & respiratory syndrome(PRRS; 15 case 4.5%), Transmissible gastroenteritis(TGE; 12 case, 3.6%). The gastrointestinal disease, such as Colibacillosis, Salmonellosis, Swine dysentery, Clostridial infection, Rotaviral infection, TGE, Porcine epidemic diarrhea(PED) and Ballantidiosis occured pro- dominently in the period of pre- and post- weaning, which were 178 cases(53.8%) and not related to occurrence according to age and season. The respiratory diseases were Atrophic rhinitis(AR), Swine enzootic pneumonia, Pneumonic pasteurellosis, Pleuropneumonia, Branchopneumonia, PRRS and which were 48 cases(14.5%) and higher prevalent in spring and summer. The viral diseases was 73 cases(22.1%) that occurred in the period of 5 weeks piglet and prevalent mainly in spring. The bacterial diseases were 188 cases(56.8%) that were not related to occurrence according to age and season. Salmonellosis was prevalent in 3 to 5 weeks piglet and mainly occurred in summer. Viral septicemia and rotaviral infection occurred after 5 weeks piglets intensively and 3 to 5 weeks, respectively. And the both occurred without relation with season. PRRS occurred after 4 weeks piglet and prevalent in summer. TGE occurred 1 to 7 days old piglets and prevalent in spring and winter. Hematologic values of anemia was decrease in number of Red Blood Cell, concentration of Hemoglobin and Hematocrit. Amikacin, cephalothin, colistin, norfloxacin were effective to E coli, and amikacin, cephalothin, nortloxacin, neomycin were effective to Salmonellra spp. but clindamycin, erythromycin, penicillin, sulfonamides were resistant to E coli and Salmonella spp.

• 대한수의사회지
• /
• 제21권8호
• /
• pp.500-502
• /
• 1985

Approximately 300 canaries died of uncertain disease in a canaries breeding farm in Jeon-Ju, between January in 1984 and April in 1985. To detect causative agents, the samples (livers, intestine, heart, and feces) were taken from 15 canaries which were in

• 대한수의사회지
• /
• 제15권9_10호
• /
• pp.505-510
• /
• 1979

At a farm raising 21 Holstein calves for meat production, 6 calves had died for 21 days with symptoms of diarrhea, inappetence, depression, dehydration and temporary rise in body temperature. Among died calves, 3 were tested pathologically and bacteriolog