• Title/Summary/Keyword: Safety Assessment Factor

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Whitening Activities of Extracts of Seomaeyakssuk (Artemisia argyi H.) (섬애약쑥 (Artemisia argyi H.) 추출물의 미백활성)

  • Lee, Hea-Jin;Lim, Mi-Hye
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.2
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    • pp.241-249
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    • 2020
  • This study investigated the whitening activity using seomaeyakssuk (Artemisia argyi H.) extract. Seomaeyakssuk was extracted from hot DW (AAD) and 70% ethanol (AAE). And confirmed safety through assessment of cytotoxicity. Also, whitening activities were measured through changes in the levels of extracellular melanin, melanin synthesis, cellular tyrosinase activity and transcription factor. The results confirmed that significant cytotoxicity does not appear in the concentration range of 50, 100, and 200 ㎍/㎖ of both extracts of this study. The production of extracellular melanin was slowed by AAD 45.0% and AAE 1.3% at 200 ㎍/㎖ concentration. Also, production of intracellular melanin was decreased AAD 37.2% and AAE 24.6%. In the case of intra cellular tyrosinase activity was reduced to AAD 49.2% and AAE 35.6% at 200 ㎍/㎖ concentration. The mRNA expression of tyrosinase, TRP-1 and TRP-2 significantly decreased by AAD 63.0%/AAE 58.0%, AAD 60.0%/AAE 56.0% and AAD 59.0%/AAE 53.0%, respectively, following the 200 ㎍/㎖ sample treatment when compared to the control. Both extracts showed efficient changes of production of whitening-related factor and transcription factor. But AAD was found to have a higher inhibitory effect than AAE. In other words, seomaeyakssuk was showed significant biological activities showing whitening without cytotoxicity. These results will be provided as fundamental data for further development of the new material of functional cosmetics to the results above.

Stability Analysis of Concrete Shear Wall System with Opening (개구부를 갖는 전단벽의 안정해석)

  • Lee, Soo-Gon;Kim, Soon-Chul;Song, Chang-Young;Song, Sang-Yong
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.9 no.4
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    • pp.109-118
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    • 2005
  • A concrete shear wall system is commonly adopted in high-rise residential apartment buildings. In the construction stage, a rectangular opening is often made for the convenience of horizontal movement of workers, and construction materials and equipment. In the case of safety or stability assessment of a shear wall, the cutout part can be a critical factor. Finite element method is adopted to investigate the elastic stability behavior of the perforated unit shear wall. The key analysis parameters are the cutout location and its size. The effect of out-of-plane bending and horizontal shear are also examined in the stability analysis.

Analysis and probabilistic modeling of wind characteristics of an arch bridge using structural health monitoring data during typhoons

  • Ye, X.W.;Xi, P.S.;Su, Y.H.;Chen, B.
    • Structural Engineering and Mechanics
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    • v.63 no.6
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    • pp.809-824
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    • 2017
  • The accurate evaluation of wind characteristics and wind-induced structural responses during a typhoon is of significant importance for bridge design and safety assessment. This paper presents an expectation maximization (EM) algorithm-based angular-linear approach for probabilistic modeling of field-measured wind characteristics. The proposed method has been applied to model the wind speed and direction data during typhoons recorded by the structural health monitoring (SHM) system instrumented on the arch Jiubao Bridge located in Hangzhou, China. In the summer of 2015, three typhoons, i.e., Typhoon Chan-hom, Typhoon Soudelor and Typhoon Goni, made landfall in the east of China and then struck the Jiubao Bridge. By analyzing the wind monitoring data such as the wind speed and direction measured by three anemometers during typhoons, the wind characteristics during typhoons are derived, including the average wind speed and direction, turbulence intensity, gust factor, turbulence integral scale, and power spectral density (PSD). An EM algorithm-based angular-linear modeling approach is proposed for modeling the joint distribution of the wind speed and direction. For the marginal distribution of the wind speed, the finite mixture of two-parameter Weibull distribution is employed, and the finite mixture of von Mises distribution is used to represent the wind direction. The parameters of each distribution model are estimated by use of the EM algorithm, and the optimal model is determined by the values of $R^2$ statistic and the Akaike's information criterion (AIC). The results indicate that the stochastic properties of the wind field around the bridge site during typhoons are effectively characterized by the proposed EM algorithm-based angular-linear modeling approach. The formulated joint distribution of the wind speed and direction can serve as a solid foundation for the purpose of accurately evaluating the typhoon-induced fatigue damage of long-span bridges.

Risk Assessment of Strong Wind over Industrial Facilities in Shipyards (조선소 시설물의 강풍 위험 평가)

  • Lee, Sung-Su;Kim, Hak-Sun;Lee, Young-Kyu;Shim, Kyu-Cheoul
    • Journal of the Korean Society of Hazard Mitigation
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    • v.9 no.4
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    • pp.21-28
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    • 2009
  • Most of domestic shipyards are located at coastal regions which are affected by typhoons nearly every year. For effectiveness of shipbuilding, shipyards contain many facilities which are light-weighted and affected dominantly by wind. In the present paper, we analyze various wind fields over a shipyard including surrounding topology and structures to evaluate the structural safety of the facilities posed in the strong wind. Extreme wind speed for a study region was estimated by typhoon Monte Carlo simulation and then used for inlet wind speed for CFD analysis for wind load on the facilities. Considering geometrical wind effects, we assess the surface pressure of the elements as the pressure factor, the ratio of surface pressure to dynamic pressure. The results show that the simulated wind speed is greater than the design wind speed for the some facilities because of the shipyard's geometry. It also shows that surrounding topography in coastal area is needed to be considered and adjustment for design wind speed at wind load standard application is necessary for mooring ship and industry facilities.

Social Support and its Predictors Among Iranian Cancer Survivors

  • Faghani, Safieh;Rahmani, Azad;Parizad, Naser;Mohajjel-Aghdam, Ali-Reza;Hassankhani, Hadi;Mohammadpoorasl, Asghar
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.22
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    • pp.9767-9771
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    • 2014
  • Background: Social support is an important factor in psycho-social well-being of cancer survivors. There is little information about level of social support and its predictors among cancer survivors in Iran or other Middle Eastern countries. The aims of present study were to determine the social support and its prediction factors among Iranian cancer survivors. Materials and Methods: In this descriptive-correlational study 187 cancer patients in one educational center and one private oncology office in northwest of Iran participated using a convenient sampling method. The data collection tool consisted of a researcher-prepared checklist and the Multidimensional Scale of Perceived Social Support Assessment (MSPSS). Data analysis was performed using SPSS statistical software with descriptive statistics and multiple linear regression analysis. Results: The total score of MSPSS was 68 from a possible score between 7 and 84. Participants believed that they received a high level of support from their family members and significant others. Multiple linear regression analysis showed that single and depressed cancer survivors and participants with lower levels of physical activity believed that they received lower levels of social support. Conclusions: Iranian cancer survivors receive high levels of social support and family members are the most important source of this support. In planning any supportive care program for Iranian cancer survivors this strength should be considered. Especially, single and depressed and patients with lower levels of physical activity need more attention.

A Study on the Performance Assessment of Nuclear Fuel Debris Filtration Using the Weighted Mean (가중평균을 이용한 핵연료 이물질 여과성능 평가에 관한 연구)

  • Park, Joon Kyoo;Lee, Seong Ki;Kim, Jae Hoon
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.41 no.2
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    • pp.149-156
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    • 2017
  • Nuclear fuel requires high reliability and safety and therefore contains debris filtering devices to prevent failure-inducing debris from entering it. The debris filtering performance of nuclear fuel is one of the most important factors for fuel integrity. Therefore, the performance must be evaluated and the measurement must be reasonable. In this study, a calculation method of the comprehensive filtering efficiency using the weighted mean was proposed to establish a standard filtering efficiency index. To confirm the suitability of the proposed method, representative debris specimens were selected and the filtering efficiency with the weighted mean was compared with the efficiency of the arithmetic mean. The weighting factor of the weighted mean was introduced to produce a fair evaluation. In addition, the analysis of the debris filtering mechanism was performed according to the size of debris specimens, and the main dimensions of the filtering feature for commercial nuclear fuel.

Rediscovering A Path to Aging in Place: Development of Housing Cooperatives for Rural Elderly

  • Lee, Hyun-Jeong
    • Architectural research
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    • v.13 no.3
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    • pp.31-40
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    • 2011
  • Profit-keeping behaviors naturally occur in the market to satisfy consumers, and the logic behind it lies in the economies of scale. On the flip side, some commodities transacted in the market are not available or can not be easily acquired unless the demand is high enough. Under this proposition, some consumers rise and find their own solution to meet the services at a reasonable cost or at an adequate level. The commonly adopted way is to establish a cooperative, and it stirs purchasing power by pooling resources and further bargains price and service quality. As a consumer cooperative, housing cooperatives notably found in rural towns enable the elderly to continue independent living. This study is to take a closer look at residential life of the rural elderly in housing cooperatives. Utilizing in-depth focus group interviews with 40 residents in four housing cooperatives, this qualitative research draws main factors affecting the decision to move in, residential assessment, and strengths and weakness of living in a housing cooperative. The primary factor influencing the moving decision is to continue to independent living in a familiar community, and the bottom line is planning ahead. Frailty and bereavement are found to be the leading occasions for them to move. The participants are satisfied with the independent living arrangement, and particularly, cited such features as safety and security, elderly-friendly design, common spaces, freedom, social activities and efficient living. Also, it is stated that some cooperative natures such as control over the property and giving a voice on management render positive impacts on the satisfaction with communal living. In spite of all the benefits and strengths, participants face with a public notion that an independent living arrangement like a housing cooperative has never done before in rural towns, so that most people recognize it as part of dependent living arrangements like nursing home.

Standardization of tunnel supporting system in karst formation (석회암 공동발달유형에 따른 터널지보패턴의 표준화에 대한 연구)

  • Kim, Sang-Hwan
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.5 no.3
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    • pp.279-289
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    • 2003
  • In karst formation area, the tunnel support system is an important factor for the tunnel safety during operation. It is also not easy to determine the tunnel supporting system in the design stage. Therefore, it is necessary to standardize the tunnel supporting system in uncertain ground condition. This paper presents the standardization of the tunnel supporting systems to be adopt in karst formation. For the tunnel planned in the project area, karst features and the expected scenarios in the tunnel area were developed based on the results of the geological and geotechnical assessment. In order to provide specific supporting system and construction details for a wide range of possible karst features, the generalized typical support systems are developed according to the classification of karst features. In addition, the initial support systems and construction sequence for each karst feature are also presented in this paper.

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Assessment of the Dieticians' Attitudes about Functional Foods and Their Needs for Training

  • Cha, Myeong-Hwa;Park, Jyung-Rewng;Choi, Jyung-Hwa
    • Preventive Nutrition and Food Science
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    • v.10 no.3
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    • pp.272-278
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    • 2005
  • The object of this study was to examine attitudes and knowledge of Korean dieticians about functional foods. We investigated their perceived knowledge and their attitudes regarding risks versus benefits, and recommendation about the use of functional foods; as well as their frequency of personal use, and the educational supports and training needs of dieticians. We developed a questionnaire to assess the dieticians' attitudes related to functional foods. This questionnaire was used for characterizing functional food-related attitudes on the basis of factor and reliability analysis in the following study. The questionnaires were distributed to 802 practicing dieticians working in Daegu and Gyeongsangbukdo. A total of 244 respondents (mean age $34\pm5.7$ years) returned the completed questionnaires through online surveys. Descriptive statistics and ANOV A were used to analyze data. Fewer than $2\%$ of dieticians claimed themselves to be knowledgeable about functional foods, more than $79\%$ consumed functional foods more than once a week, and $88\%$ of dieticians expressed an interest in receiving training about functional foods. Dieticians had favorable attitudes about the rewards from functional foods but were not confident about the safety and usage recommedation of these foods. The level of knowledge and educational support at their universities about functional foods affected the dieticians' attitudes regarding the rewards from and recommendation about the use of functional foods. These results suggest a need for additional educational opportunities to facilitate a better understanding of the risks and benefits of functional foods and their proper usage. Dietetics professionals must adapt to changes in health practices through effective educational programs integrating sufficient knowledge about functional foods.

A Study on the Pattern of Consumption Behavior of Environmentally-friendly Agricultural Products by Housewives and an Assessment of the Need for Environmentally-friendly Agricultural Products in Childcare Centers in Jeonju (전주지역 유아기 어머니의 친환경 농산물 이용실태 및 보육시설에서의 친환경 급식 요구도 조사)

  • Rho, Jeong-Ok;Kim, Hyun-Jin
    • The Korean Journal of Food And Nutrition
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    • v.25 no.2
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    • pp.215-223
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    • 2012
  • The principal objective of this study was to evaluate the consumption behavior of housewives in the Jeonju area with respect to their use of environmentally-friendly agricultural products(EAPs) and to assess the need for EAPs in childcare centers also in the Jeonju area. Self-administered questionnaires were given to and collected from 278 housewives 42.4% of whom employed and 57.6% were unemployed. Statistical data analysis was performed on the data collected using SPSS v. 12.0. The average score of awareness about EAPs was $3.57{\pm}0.56$. The percentage of subjects who purchased EAPS was 76.3% regularly. On this group, 40.3% purchased EAPs 1~2 times in week. Unemployed housewives purchased more than employed housewives by a statistically significant margin(p<0.05). The most-purchased EAPs were vegetables. The average satisfaction score that housewives reported in relation to foodservice provided in childcare centers was $3.66{\pm}0.58$. About 65% of the respondents felt that the EAPs-foodservice in childcare centers was an important factor for them in choosing of a childcare centers. Approximately 42% of the housewives responded that EAPs-foodservice in childcare centers was needed to improve the safety of foodservice provided in chidcare centers. The percentage of subjects who wanted to expand EAPs-foodservice in childcare centers even though the parents would have to bear some of the financial burden was 42.5%. A higher proportion of employed housewives wanted to expand EAPs-foodservice in childcare centers more than unemployed housewives, and this finding was statistically significant(p<0.05).