• Title/Summary/Keyword: Safety Assessment Factor

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Cumulative Risk Assessment of Organophosphorus Pesticides in the Diet (식품을 통한 유기인계농약류의 동시노출위해성평가)

  • 이효민;한지연;윤은경;김효미;황인균;최동미;이강봉;원경풍;송인상
    • Journal of Food Hygiene and Safety
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    • v.16 no.1
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    • pp.21-26
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    • 2001
  • Risk assessment traditionally are conducted on individual chemicals; however, humans are exposed to multiple chemicals in daily life. The organophosphorus (OP) pesticides are considered in a single risk assessment because they act by a common mechanism of toxicity, and there is likely to be expose to multiple OP pesticides simultaneously or sequentially. The OP pesticides act by inhibiting the enzyme acetylcholinesterasc (AChE) and have available extensive database. AChE is widely distributed throughout the body, most importantly in the nervous system. Inhibition of AChE results in accumulation of acetylcholine in the nervous system that results in clinical signs of cholinergic toxicity, including increased salivation and lacrimation, nausea and vomiting, muscle fasciculation, lethargy and fatigue, among others. To conduct an exposure assessment for pesticides in the diet, we need to know the food consumption patterns of the populations, and the pesticide residue levels in the foods that are consumed. This study was conducted to identify cumulative dietary risk due to multiple OP pesticides that can be exposed through various foods. Total 22 food samples including cereals, vegetables and fruits were collected randomly two times from food markets in several sites (4 cities). The subjected foods were selected by regarding of highly consumed foods to general Korean people. The 12 OP pesticides including Acephate, Azinphos-methyl, Chlorpyrifos, and Diazinon were monitored. For the exposure assessment, general adult group of 60 kg body weight was regarded as target population and food consumption data suggested by Lee et al. (2000) were used as consumed value of individual food. Analyses of samples for OP pesticides have been carried out according to the multiclass multiresidue analysis method and acephate and methamidophos analysis method of Korea Food Code. In general the levels of OP pesticides found in the food samples were very low or not detected.

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Comparison of Measured and Predicted $^3H$ Concentrations in Environmental Media around the Wolsung Site for the Validation of INDAC Code (주면피폭선량 평가코드(INDAC)의 검증을 위한 월성원전 주면 삼중수소 농도 실측치와 예측치의 비교 평가)

  • Jang, Si-Young;Kim, Chang-Kyu;Rho, Byung-Hwan
    • Journal of Radiation Protection and Research
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    • v.25 no.2
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    • pp.75-80
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    • 2000
  • The predicted results of INDAC code were compared with measured $^3H$ concentrations in air and pine-needle around the Wolsung site. The optimal sets of input data to INDAC were in addition selected by comparing the measured values with the predicted values of INDAC based on various conditions such as the release modes of effluents into the environment, the classification of wind classes, and the consideration of terrain. The predicted $^3H$ concentrations in air and pine-needle were shown to have good agreement with measured values, although there are some limitations such as uncertainties in measured values, complex topology around the site, and the land-sea breeze effects. The assumption on the $^3H$ behavior in vegetables or plants that the ratio of $^3H$ concentration in plant water to $^3H$ concentration in atmospheric water is 1/2 was shown to be conservative in terms of the audit calculation performed by the regulator. It was also found that data sets based on mixed mode and no terrain data were not appropriate for the audit calculation ensuring the compliance with regulations. Thus, if the mixed mode is considered as the release mode of effluents into the environment, meteorological data measured at 58 m height and terrain data should be used to evaluate the atmospheric dispersion factor.

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Suggestions for Enhancing Sampling-Based Approach of Seismic Probabilistic Risk Assessment (샘플링기반 지진 확률론적 리스크평가 접근법 개선을 위한 제언)

  • Kwag, Shinyoung;Eem, Seunghyun;Choi, Eujeong;Ha, Jeong Gon;Hahm, Daegi
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.34 no.2
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    • pp.77-84
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    • 2021
  • A sampling-based approach was devised as a nuclear seismic probabilistic risk assessment (SPRA) method to account for the partially correlated relationships between components. However, since this method is based on sampling, there is a limitation that a large number of samples must be extracted to estimate the results accurately. Thus, in this study, we suggest an effective approach to improve the existing sampling method. The main features of this approach are as follows. In place of the existing Monte Carlo sampling (MCS) approach, the Latin hypercube sampling (LHS) method that enables effective sampling in multiple dimensions is introduced to the SPRA method. In addition, the degree of segmentation of the seismic intensity is determined with respect to the final seismic risk result. By applying the suggested approach to an actual nuclear power plant as an example, the accuracy of the results were observed to be almost similar to those of the existing method, but the efficiency was increased by a factor of two in terms of the total number of samples extracted. In addition, it was confirmed that the LHS-based method improves the accuracy of the solution in a small sampling region.

A Study on the Field Application of the Measurement Technique for Static Displacement of Bridge Using Ambient Vibration (상시 진동을 이용한 교량 정적 처짐 산정 기술의 현장 적용성 연구)

  • Sang-Hyuk Oh;Dae-Joong Moon;Kwang-Myong Lee
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.11 no.4
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    • pp.355-363
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    • 2023
  • In safety assessment of a aged bridge, dynamic characteristics and displacement are directly related to the rigidity of the structural system, especially displacement is the most important factor as the physical quantity that the bridge user can directly detect. However, in order to measure the displacement of the bridge, it is difficult to install displacement sensors at the bottom of the bridge and conduct traffic blocking and loading tests, resulting in increased costs or impossible measurements depending on the bridge's environment. In this study, a method of measuring the displacement of a bridge using only accelerometers without installing displacement sensors and ambient vibration without a loading test was proposed. For the analysis of bridge dynamic characteristics and displacement using ambient vibration, the mode shape and natural frequency of the bridge were extracted using a TDD technique known to enable quick analysis with simple calculations, and the unit load displacement of the bridge was analyzed through flexibility analysis to calculate static displacement. To verify this proposed technology, an on-site test was conducted on C Bridge, and the results were compared with the measured values of the loading test and the structural analysis data. As a result, it was confirmed that the mode shape and natural frequency were 0.42 to 1.13 % error ratio, and the maximum displacement at the main span was 3.58 % error ratio. Therefore, the proposed technology can be used as a basis data for indirectly determine the safety of the bridge by comparing the amount of displacement compared to the design and analysis values by estimating the displacement of the bridge that could not be measured due to the difficulty of installing displacement sensors.

A Study on Dynamic Capacity Assessment of PSC Box Girder High Speed Railway Bridges Using Time Series Load (시계열하중을 이용한 PSC 박스 거더 고속철도교량의 동적성능 평가에 관한 연구)

  • Han, Sung Ho;Bang, Myung Seok;Lee, Woo Sang
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.30 no.3A
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    • pp.211-219
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    • 2010
  • The design concept of high speed railway bridges is applied to a method for increasing the stiffness of existing bridge structures considering the impact factor by a static load. Generally, the process of structural design would be relied upon an advanced foreign technology. However, the dynamic amplification factor (DAF) and dynamic capacity assessment of high speed railway bridges may be conducted essentially a detailed estimation because the resonance phenomenon is affected by the long length (380 m) and high speed (300 km/h) moving of a high speed railway (Korea Train eXpress: KTX). Therefore, this study will be examined the dynamic capacity of the typical PSC Box Girder high speed railway bridge efficiently, and offered the basic information for the reasonable structural design. For this, the static analysis is conducted considering the load line diagram of KTX based upon existing references. In addition, the KTX moving load is transformed into the time series load considering various analytical variables. The time history analysis is assessed reasonable using the transformed time series load. At that time, analytical variables for calculating the time series load are considered loading node distance, time increment and KTX velocity variation etc. The dynamic capacity of the PSC Box Girder high speed railway bridge is examined based upon the FE analysis result systematically. The structural safety is assessed quantitatively in accordance with the related regulation of the inside and outside of the country.

Bioconcentration Factor(BCF) of Perchlorate from Agricultural Products and Soils (농산물과 토양에 대한 퍼클로레이트 함량 평가 및 생물농축계수 산출)

  • Kim, Ji-Young;Kim, Min-Ji;Lee, Jeong-Mi;Kim, Doo-Ho;Park, Ki-Moon;Kim, Won-Il
    • Korean Journal of Environmental Agriculture
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    • v.32 no.3
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    • pp.224-230
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    • 2013
  • BACKGROUND: Perchlorate(${ClO_4}^-$) is an anion that is extremely water-soluble and environmentally stable. It mostly exists in the form of sodium perchlorate, ammonium perchlorate and potassium perchlorate which are used in rocket fuels, propellants, ignitable sources, air bag inflation systems and explosives. Perchlorate can be taken into the thyroid glands and interfere with iodide uptake. The determination of perchlorate in agricultural products is important due to its potential health impact on humans. The objective of this study was to determine the perchlorate concentrations in the samples of various agricultural products and soils. METHODS AND RESULTS: In this study, samples of cereal(Rice, Barley, Corn, Bean), vegetable(Spinach, Lettuce, Sesame, Chives, Chili, Pumpkin, Tomato), fruit(Apple, Pear, Tangerine, Grape) were analyzed for perchlorate contents. Perchlorate concentrations were analyzed by liquid chromatography-tandem mass spectrometry. The results showed that agricultural products respectively contained perchlorate concentrations in the range of : cereals N.D.~$7.46{\mu}g/kg$, vegetables $0.52{\sim}23.06{\mu}g/kg$, fruits $0.19{\sim}2.66{\mu}g/kg$. Bioconcentration factor was in the order of : vegetables > cereals > fruits. Bioconcentration factor was highest follwed by Sesame 37.88, Corn 21.51, Spinach 10.57, Tangerine 4.39, Chives 2.89 and Lettuce 1.90. The recoveries of perchlorate from spiked agricultural products and soils ranged from 87.72~111.26% and 102.09~111.23%. CONCLUSION(S): The health risk assessment results obtained in this study are lower than the RfD(Reference Dose, 0.0007 mg/kg/body weight/day) value as suggested by the Integrated Risk Information System(US IRIS). Our results indicate that, people currently exposed to perchlorate from agricultural products consumption are considered as safe.

A Study on the Marine Traffic Risk Assessment by using Ship Handling Simulator (선박조종 시뮬레이터를 이용한 해상교통 위험도 평가에 관한 연구)

  • Park, Young-Soo;Kim, Jong-Sung;Kim, Chol-Seong;Yong, Jeong-Jae;Lee, Hyong-Ki;Jeong, Eun-Seok
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.19 no.2
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    • pp.138-144
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    • 2013
  • Large and small marine accidents which are related to vessel's navigation are happening continuously and these maritime accidents have caused loss of lives and properties, and serious maritime environmental pollution damage. It is also true that maritime pollution damage is increasing due to these accidents, probability of growth of seaborne volume and complicated maritime traffic environment. Korea, recently, is developing an evaluation index which can assess sea risk through the evaluation of maritime traffic environment and provide danger and general information with relation to maritime traffic environment on target sea area to evaluate maritime traffic safety. In this paper, we intend to confirm the validity of maritime traffic safety on the basis of vessel navigator's risk consciousness and various sailing conditions by using the ship handling simulator. To confirm the validity of sailing vessel's maritime traffic safety, we use analysis of variance. By using analysis of variance, we analyze vessel navigator's characteristics, distance, speed and encounter type between vessels. Through multiple comparison of each factor's risk difference, we can confirm the change of numerical value of risk difference in statistical aspect.

Toxicity Assessment and Establishment Acceptable Daily Intake of Pyrimisulfan (피리미설판(Pyrimisulfan)의 독성평가와 일일섭취허용량 설정)

  • Jeong, Mi-Hye;Park, Kyung-Hun;Park, Jae-Eup;Kwack, Seung-Jon;Kim, Young-Bum;Han, Bum-Seok;Son, Woo-Chen
    • The Korean Journal of Pesticide Science
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    • v.15 no.2
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    • pp.208-217
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    • 2011
  • Pyrimisulfan is a herbicide. In order to register this new pesticide, the series of toxicity data on animal testing were reviewed to evaluate its hazards to consumers and also to determine its acceptable daily intake. Pyrimisulfan was excreted mostly by feces. It has low acute oral toxicity while it has no dermal, ocular irritation and skin sensitization (As the result of subchronic and chronic toxicity and carcinogenicity showed changes of hematology and liver.). Two-generation reproduction toxicity, genotoxicity, carcinogenicity and prenatal development toxicity were not proven. Therefore, the ADI for Pyrimisulfan is 0.1 mg/kg/ bw/day, based on the NOAEL of 10 mg/kg/ bw/day of 90-days repeated dose oral toxicity study in dogs while applying an uncertainty factor of 100.

Risk Evaluation and Analysis on Simulation Model of Fire Evacuation based on CFD - Focusing on Incheon Bus Terminal Station (CFD기반 화재 대피 시뮬레이션 모델을 적용한 위험도 평가 분석 -인천터미널역 역사를 대상으로)

  • Kim, Min Gyu;Joo, Yong Jin;Park, Soo Hong
    • Spatial Information Research
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    • v.21 no.6
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    • pp.43-55
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    • 2013
  • Recently, the research to visualize and to reproduce evacuation situations such as terrorism, the disaster and fire indoor space has been come into the spotlight and designing a model for interior space and reliable analysis through safety evaluation of the life is required. Therefore, this paper aims to develop simulation model which is able to suggest evacuation route guidance and safety analysis by considering the major risk factor of fire in actual building. First of all, we designed 3D-based fire and evacuation model at a subway station building in Incheon and performed fire risk analysis through thermal parameters on the basis of interior materials supplied by Incheon Transit Corporation. In order to evaluate safety of a life, ASET (Available Safe Egress Time), which is the time for occupants to endure without damage, and RSET (Required Safe Egress Time) are calculated through evacuation simulation by Fire Dynamics Simulator. Finally, we can come to the conclusion that a more realistic safety assessment is carried out through indoor space model based on 3-dimension building information and simulation analysis applied by safety guideline for measurement of fire and evacuation risk.

A Study on Evaluation of the Rurality by the Distance of View (조망거리에 따른 농촌경관의 농촌다움 평가에 관한 연구)

  • Shin, Min-Ji;Shin, Ji-Hoon
    • Journal of Korean Society of Rural Planning
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    • v.21 no.2
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    • pp.63-77
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    • 2015
  • Improve the rural views of the Government and the municipalities with the intention of rural landscape planning. However, rural scenery evaluation of landscape types and element categories, landscape scenes, such as the valuation of resources selected, form a coherent system and ecological point of view is not only a Visual perspective of evaluation, or evaluation is made. This study evaluates the rural landscape through the rural landscape for rurality is implemented can explain the image. Rural amenity 100 represented the rural landscape in rurality with photos of photos, and scenes, photos, location-based rural Vista rurality landscapes drawn components. Selected landscape photography scenic landscapes in the u.s. survey and image vocabularies through surveys is representative of the landscape in rurality of each Vista location-specific photos and images began extracted factors. As a result, the Distant view is a town and village in the rolling hills of the surrounding environment is an image behind the Vista Skyline, Farmland Rural village forests, Behind the hills, Individual housing roof, Housing arrangement, The number of household includes landscape components. Factor analysis 'openness', 'intimacy', 'activity', 'complexity', 'safety' was down to five factors, such as a description of the overall factors that force was 66.45 percent. Middle distance view is close to being out of town houses and village environment, an image in the skyline hills Vista, farmlands, village forests, rolling hills, behind the scenes of the housing component of the neck, the sperm will honor an individual factor analysis results are 'intimacy', 'safety', 'openness', 'specificity', 'complexity' five factors the whole description of the capacity factors compared to 67.24 percent. Close-range view is mainly in Vista village embraced the individual elements and an image of a harmonious location in the surroundings of the sperm, individual houses, fences, gates, courtyard, Garden, garage, agricultural facilities, including, but not limited to, factors assay but an 'intimacy', 'complexity', 'safety', 'activity', 'openness' five factors, such as a description of the overall factors that force was 65.29%. This research seeks to determine the extent to which rurality of rural landscape Vista by location attributes and elements and representative officer in photo selection and rurality to extract the image. To date, followed by a comprehensive study, which was presented through the readjustment could not overlook the Visual elements. The future rural development officer for the evaluation of rural landscape classification and quantitative and objective assessment will have to come up with ways to do.