• Journal of Yeungnam Medical Science
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• v.36 no.2
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• pp.109-114
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• 2019

Background: Transforaminal epidural block (TFEB) is an effective treatment option for radicular pain. To reduce complications from intravascular injection during TFEB, use of imaging modalities such as real-time fluoroscopy (RTF) or digital subtraction angiography (DSA) has been recommended. In this study, we investigated whether DSA improved the detection of intravascular injection during TFEB at the whole spine level compared to RTF. Methods: We prospectively examined 316 patients who underwent TFEB. After confirmation of final needle position using biplanar fluoroscopy, 2 mL of nonionic contrast medium was injected at a rate of 0.5 mL/s under RTF; 30 s later, 2 mL of nonionic contrast medium was injected at a rate of 0.5 mL/s under DSA. Results: Thirty-six intravascular injections were detected for an overall rate of 11.4% using RTF, with 45 detected for a rate of 14.2% using DSA. The detection rate using DSA was statistically different from that using RTF (p=0.004). DSA detected a significantly higher proportion of intravascular injections at the cervical level than at the thoracic (p=0.009) and lumbar (p=0.011) levels. Conclusion: During TFEB at the whole spine level, DSA was better than RTF for the detection of intravascular injection. Special attention is advised for cervical TFEB, because of a significantly higher intravascular injection rate at this level than at other levels.

• Journal of Yeungnam Medical Science
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• v.36 no.1
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• pp.50-53
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• 2019

Awareness during general anesthesia occurs in approximately 0.1-0.2% of cases; nevertheless, particular attention is required because it can lead to critical complications including insomnia, depression, anxiety, and post-traumatic stress disorder. To prevent these complications, bispectral index (BIS) and end-tidal anesthetic gas (ETAG) concentration monitoring are commonly used to examine patient consciousness during surgery. In the present case, an 80-year-old man was scheduled for total gastrectomy. Anesthesia was maintained using desflurane 4.0-5.0% vol, oxygen, and nitrous oxide. The authors simultaneously monitored BIS, which was maintained between 37 and 43, and ETAG, which was maintained between 0.9 and 1.2 minimum alveolar concentration (MAC). After the operation, however, the authors were surprised to learn that the patient complained of awareness during anesthesia. Although BIS and ETAG concentration monitoring are useful in preventing awareness during anesthesia, they cannot be completely trusted. Even though BIS was maintained at approximately 40 and ETAG at 0.7-1.3 MAC, awareness during anesthesia occurred.

• Journal of Fashion Business
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• v.26 no.4
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• pp.123-135
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• 2022

In Korea, business guidelines for nurturing professional manpower in the cosmetic industry are insufficient despite the implementation of legislation and certification system for customized cosmetics. Therefore, in this study, guideline design for customized cosmetics businesses was studied. As a research method, literature on domestic and foreign market conditions and cases of each business type of the customized cosmetics market were analyzed. In addition, a focus group interview was conducted on the guidelines by creating a group of professionals and employees in the customized cosmetics industry. As a result, it was found that the guidelines for individual business owners of customized cosmetics were institutionalized into 4 types, and essential information needed for introduction of the customized cosmetics into the market and information needed for general practice should be provided. It is expected that this study will be developed as a guideline that can guide the growth of the cosmetic industry and the vitalization of the customized cosmetics business in the future.

• Journal of Dental Anesthesia and Pain Medicine
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• v.16 no.4
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• pp.289-294
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• 2016

Background: Control of postoperative pain is an important aspect of postoperative patient management. Among the methods of postoperative pain control, patient-controlled analgesia (PCA) has been the most commonly used. This study tested the convenience and safety of a PCA method in which the dose adjusted according to time. Methods: This study included 100 patients who had previously undergone orthognathic surgery, discectomy, or total hip arthroplasty, and wished to control their postoperative pain through PCA. In the test group (n = 50), the rate of infusion was changed over time, while in the control group (n = 50), drugs were administered at a fixed rate. Patients' pain scores on the visual analogue scale, number of rescue analgesic infusions, side effects, and patients' satisfaction with analgesia were compared between the two groups. Results: The patients and controls were matched for age, gender, height, weight, and body mass index. No significant difference in the mount of drug administered was found between the test and control groups at 0-24 h after the operation; however, a significant difference was observed at 24-48 h after the operation between the two groups. No difference was found in the postoperative pain score, number of side effects, and patient satisfaction between the two groups. Conclusions: Patient-controlled anesthesia administered at changing rates of infusion has similar numbers of side effects as infusion performed at a fixed rate; however, the former allows for efficient and safe management of postoperative pain even in small doses.

• Journal of Fashion Business
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• v.20 no.1
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• pp.1-16
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• 2016

Korean cosmetic distribution channels were formerly divided into sales visits and specialty shops, which made up the entire cosmetics market. However, recently the market and cosmetic distribution channels have become much more diversified. Thus, research for this study focused on the usage and purchase situations of cosmetic distribution channels depending on cosmetic type perception. This study also focused on the intent to purchase cosmetics by a cosmetic distribution channel in order to provide a precise cognitive background of consumers regarding cosmetic distribution channels. In doing so, the competitiveness of those channels could be procured and the causal relationships between these variables can be investigated. To achieve these purposes, the research model and hypotheses were derived through literature research on the cosmetics industry, cosmetic distribution channels, and consumers' intent to purchase. A survey was implemented from September $1^{st}$ to $14^{th}$, 2014 for empirical testing. and was given to female consumers in their 20s. 468 out of 500 surveys were collected; a total of 415 were used for analysis while the others were excluded due to with unreliable responses. The SPSS 21.0 program was used for analysis of materials. The overall conclusion of this study is that there is a relationship between perception of cosmetic distribution channels and intent to purchase. The above research results may stimulate establishment of marketing implications and research material when establishing marketing strategies to promote cosmetic distribution and consumption.

• Journal of Fashion Business
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• v.21 no.1
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• pp.88-98
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• 2017

This study intended to investigate correlations between the consumption tendency, determination factors of the distribution of Korean cosmetics, and purchasing patterns of Korean cosmetics. This study investigated characteristics and differences between each factor by analyzing consumption tendency, determination factors of distribution channels, and purchasing patterns of Korean cosmetics of adult women in their 20 ~ 50s who have used Korean cosmetics and reside in Beijing, China. It also, investigated the effect of the shopping propensity of consumers on determination factors of the distribution channels and purchasing patterns of Korean cosmetics. According to the results of our investigation, it was identified that 'pleasure-seeking tendency' and 'brand-seeking tendency' have postive effects on 'service', and 'pleasure-seeking tendency', 'brand-seeking tendency', and 'rational purchasing propensity' have positive effects on 'professionalism'. In regards to the effect of shopping propensity on purchasing patterns of Korean cosmetics, it was identified that 'brand-seeking tendency' has a positive effect on 'planned purchasing behavior', 'brand reputation seeking behavior', and 'dedicated purchasing behavior'. It was verified that 'rational purchasing propensity' has positive effect on 'planned purchasing behavior', 'pleasure-seeking tendency' and 'trend-seeking tendency' on 'brand reputation seeking behavior', and 'trend-seeking tendency' on 'dedicated purchasing behavior'. This study is expected to provide basic data for Korean cosmetics brands to use for improving the marketing of products entering the Chinese market by using appropriate distribution channels. These channels are determined through identifying the correlation of each factor consumption tendency of Chinese women, determination factors of the distribution channels Korean cosmetics, and purchasing patterns of Korean cosmetics.

• Fashion & Textile Research Journal
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• v.24 no.4
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• pp.460-470
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• 2022

Customized cosmetics are emerging as a consumer product that companies should pay attention to in the beauty industry due to the combination of market trends and institutional introduction of customized cosmetics. In this study, six offline service brands and online service brands currently in Korea were selected to understand the current status of domestic customized cosmetics online and offline services and to derive detailed characteristics, and the cases of each brand were analyzed. The results are as follows. First, customized cosmetics services could be classified online and offline. Second, customized cosmetics brands could be divided into general brand types and brand extension types. Third, skin data measurements could be classified into genetic analysis, big data-based surveys, and device measurements. Fourth, customized cosmetics manufacturing could be classified into a device manufacturing system, a consultant manufacturing system, and an individual production process system. Fifth, customized cosmetics distribution and delivery could be classified into same-day sales, general delivery, and regular delivery. The results of this study are meaningful in that they have identified and analyzed the current status of personalized cosmetics on-line and offline systems in recent trends, and it was confirmed that creative attempts in the domestic customized cosmetics market continue to change. It is hoped that this study will provide information and ideas to the beauty industry and related experts in the future and be used as basic data for customized cosmetics marketing

• Microbiology and Biotechnology Letters
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• v.51 no.1
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• pp.93-98
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• 2023

Nuruk is a starter culture of Korea manufactured by spontaneous fermentation of grains. We isolated bacteria of the genera Bacillus and Staphylococcus, and lactic acid bacteria (LAB) from eight commercial nuruk samples collected from four districts of Korea using selective agar media and identified them based current taxonomic standards. Bacillus was detected in all samples, but Staphylococcus or LAB were not detected in three samples. In seven samples, except one sample scored the highest cell number of LAB, Bacillus and Staphylococcus were counted as the highest and the lowest numbers, respectively. Six species of Bacillus were identified, and B. subtilis, B. velezensis, and B. licheniformis were predominant species. Nine species of coagulase-negative Staphylococcus were identified, and the predominance of S. pseudoxylosus and S. saprophyticus was confirmed. Ten species of LAB including Enterococcus, Lactobacillus and close relatives, Pediococcus, and Weissella were identified. P. pentosaceus was identified as the predominant species.

• Journal of the Korean Electrochemical Society
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• v.17 no.1
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• pp.30-36
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• 2014

Redox complexes to transport electrons from enzyme to electrodes are very important part in glucose sensor. Pentacyanoferrate-bound aniline ($Fe(CN)_5$-aminopyridine), was prepared as a potential redox mediator in a glucose dehydrogenase (GDH)-glucose sensor. The synthesized pyridyl-$NH_2$ to pentacyanoferrate was characterized by the electrochemical and spectroscopic methods. A amperometric enzyme-linked electrode was developed based on GDH, which catalyses the oxidation of glucose. Glucose was detected using GDH that was co-immobilized with an $Fe(CN)_5$-aminopyridine and gold nano-particles (AuNPs) on ITO electrodes. The $Fe(CN)_5$-aminopyridine and AuNPs immobilized onto ITO electrodes provided about a two times higher electrochemical response compared to that of a bare ITO electrode. As glucose was catalyzed by wired GDH, the electrical signal was monitored at 0.4 V versus Ag/AgCl by cyclic voltammetry. The anode currents was linearly increased in proportion to the glucose concentration over the 0~10 mM range.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.20 no.1
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• pp.1-13
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• 2020

Purpose: Gaucher disease (GD), which is the most prevalent lysosomal storage disorder worldwide, is caused by mutations in the glucocerebrosidase gene (GBA). GD is divided into three clinical subtypes based on the appearance of neurological symptoms. Type 1 GD is a chronic non-neuronopathic disease, and types 2 and 3 are acute neuronopathic and chronic neuronopathic forms, respectively. Neuronopathic GD types 2 and 3 are characterized by increased levels of glucosylceramide (GlcCer) and glucosylsphingosine (GlcSph) in the brain, leading to massive loss of neurons. Methods: DNA damage and subsequent apoptosis of H4 cells were observed following neuroglioma H4 cell culture with GlcCer or GlcSph. Neuronal cell apoptosis was more prominent upon treatment with GlcSph. Results: When H4 cells were treated with GlcSph in the presence of tubacin, a histone deacetylase 6 inhibitor (HDAC6i), attenuation of both DNA damage and a reduction in the protein expression levels of GlcSph-induced apoptosis-associated factors were observed. Conclusion: These findings indicated that GlcSph played a prominent role in the pathogenesis of neuronopathic GD by inducing apoptosis, and that HDAC6i could be considered a therapeutic candidate for the treatment of neuronopathic GD.