• Korean Journal of Food Science and Technology
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• v.34 no.1
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• pp.123-127
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• 2002

Echinacea is a North American native medicinal herb used traditionally for wounds, burns, snake or insect bites, colds, infections, and inflammation by indigenous Americans. We investigated the effects of the root and stem of fresh Korean-grown Echinacea angustifolia methanol extracts and fractionation extracts on the cytotoxicity against cancer cells (HL60, 3LL). The extracts were prepared by step-wise fractionation of methanol extracts of Echinacea angustifolia using hexane, chloroform, ethyl acetate, buthanol, and water. From the tests, root and stem parts of Echinacea showed the cytotoxic effect on cancer cells. The cytotoxie rate of the ethyl acetate fraction of the root parts showed 79% against HL60 cells at low concentration (0.125 mg/mL), and hexane fraction of the root and stem parts gradually increased as the concentration of samples increased, and the root parts showed 82% at 1.0 mg/mL concentration against HL60 cells, chloroform fraction of the root part showed 78.4% against HL60 cells and 68.4% on 3LL cells at 1.0 mg/mL concentration, water and butanol fraction of these results, it is considered that ethyl acetate fraction of the root and stem parts showed 60.1% to 77.1% against HL60 cells, after testing by MTT assay system. From these results, it is considered that ethyl acetate fraction of the Echinacea angustifolia root parts has stronger anticancer effects than any other fractions in vitro.

• Journal of agricultural medicine and community health
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• v.8 no.1
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• pp.12-18
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• 1983

This study was carried out in identify the accidents of the residents in the rural community for a year from January to December in 1980 in the area of Bugae Myun, Gunwee Gun, Kyungpook province in Korea. The annual incidence was 3.9% and there was significant difference between sexes(p < 0.01) ; 5.5% in male, 2.3% in female. The age group of 50-59 showed the highest incidence as 5.7%. In summer the incidence was the highest as 37.5% and in winter, the lowest as 18.7%. Farming tool was the most frequent cause of accident as 44.3% and followed by insecticide and bite of snake and dog, etc. Hands and fingers were the most frequent injured parts as 33.0% and upper extremities(40.3%) were twice as high as the lower ones(20.5%). By kinds of injuries, laceration was highest as 33.0% and followed by contusion(24.4%) and abrasion(15.9%). Average duration of treatment was 6.1 days and most of the cases(85.2%) were within 10 days. Average duration of labor loss was 8 days and 84.6% of the total were less than 10 days. Twenty-six cases had some parts of their bodies lost due to accidents and five cases died from drownina and poisoning.

• Parasites, Hosts and Diseases
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• v.22 no.2
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• pp.223-228
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• 1984

Seven cases of surgically proven sparganosis were serologically tested by means of microELISA for their specific IgG antibody levels. For that purpose, crude saline extract of spargana from snake, Natrix tigrina lateralis was prepared and used as antigen. The sparganosis sera were also tested with Paragonimus and Cysticercus antigens to observe the cross reactivity. A total of 71 sera from normal control, ectopic and pulmonary paragonimiasis, clonorchiasis, cysticerCOSIS and Taenia saginata cases were also included. Except for one case of old calcified infection, all of 6 human sparganosis showed higher serum levels of specific IgG antibody when the differential point of positive reaction was set at the absorbance value of 0.25 (the sensitivity being 85.7%). In control and other helminthic infections, all except 3 cases of T. saginata infection showed negative reaction to sparganum antigen (the specificity being 90.7%). None of sparganosis cases showed cress reactivity to Paragonimus and Cysticercus antigens. Undiluted cerebrospinal l1uid also showed high levels of antibody when central nervous system was invaded. The serologic diagnosis by means of micro ELISA could be a useful tool in epidemiological study of human sparganosis in susceptible population, as well as in individual diagnosis.

• Parasites, Hosts and Diseases
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• v.22 no.2
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• pp.229-237
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• 1984

The migration and distribution pattern of spargana in mouse body was observed after experimental infection through mouth. The spargana were obtained from the snake, Natris tigrina lateralis, caught in Hoengseong-gun, Kangwon-do. A total of 28 male mice (ICR strain), 21∼259 in body weight, were fed each with 5 scolices (and necks) of spargana and killed after 10 minutes to 14 days. Systemic autopsy was performed on each mouse to recover the spargana. The results are as follows: 1. The spargana were found to penetrate into the stomach or duodenal wall of mice as early as 10 minutes after infection. They completed the penetration within 30 minutes and appeared in abdominal cavity. It was observed that spargana did not migrate tangentially along the gut wall but directly perforated the wall. 2. After 1 hour to 1 day the majority of spargana distributed in abdominal cavity of mice except a few which migrated to muscles or subcutaneous tissues. 3. It was within 7 days that nearly all of the spargana migrated to subcutaneous tissues. Out of total 28 in number found from subcutaneous tissues, 13 distributed around neck region, 12 around trunk and other 3 on head of mice and the most common sites were submandibular and subscapular areas. There was nearly no host tissue reaction to migrating spargana. 4. The initial length of spargana given was 4 mm in average but it increased to 12 mm after 7 days and to 35 mm after 14 days. The results suggest that spargana orally given to mice penetrate the gut wall within 30 minutes followed by escaping into abdominal cavity, and after passing through thoracic cavity or abdominal wall they anally Localize in subcutaneous tissues chieay around neck region within 7 days.

• Journal of agricultural medicine and community health
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• v.22 no.2
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• pp.239-252
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• 1997

A questionnaire survey including stool examination for the parasite ova, skin test, and enzyme-linked immunosorbent assay (ELISA) of the liver fluke to find the factors related with the prevalence of the parasite infestation was done toward 118 residents living in three villages of Song-jung, Yi-jung, and Chim-gok of Okok-myun, Goksung County, South Cholla Province. The results are as follows : 1. The prevalence of Clonorchis sinensis ova by the stool examination was 46.6%. The sensitivity and specificity of skin test to egg-positive cases were 63.5% and 68.9%. The sensitivity and specificity of ELISA to egg-positive clonorchiasis were 100% and 34.9%. 2. The prevalence of Clonchiasis was higher in male than in female. 45~64 year old group was the highest among age groups, and the longer the duration of living in the present residence was, the higher the prevalence was shown statistically significantly (p<0.01). 3. The present drinker had higher prevalence of Clonorchiasis significantly than the past drinker or non-drinker, and the more the frequency of drinking the higher the prevalence was shown significantly (p<0.05). 4. Those who took raw fish had significantly higher than persons who didn't take it or take cooked fish(p<0.05) and prevalence showed the tendency to be increased as the frequency to take raw fishes increased significantly(p<0.05). 5. Those who had taken a raw sweet fish(Plecoglossus altivelis) or snake-headed fish(Ophicephalus argus) showed significantly higher prevalence of infection with liver fluke than persons who didn't take the raw fish. 6. While 56.4% of persons infected with Clonorchiasis answered that they were healthy, only 13.0% of the subjects were careful for their health, and 41.8% experienced tests to diagnose liver flukes before they were examined by this survey. 7. While 56.4% of infected persons thought the prevalence was high in their community, 54.0% were afraid to be infected, 47.1% thought the infection might destroy their health, 25.5% took treatment drugs, and 18.2% took raw fish continuously after treatment. The above results confirmed that Goksung area was highly prevalent in Clonorchiasis, so it was necessary to push effective preventive program against liver fluke infection together with the program to diagnose and treat existing infected persons.

• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.3
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• pp.447-463
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• 2001

Dendroaspis natriuretic peptide (DNP), a fourth member of the natriuretic peptide isolated from the venom of the Dendroaspis angusticeps snake, has been reported to be present in human plasma and atrial myocardium and caused vasorelaxation and diuresis in experimental animals. However, it is uncertain whether they are present in peripheral organs other than the heart and its further physiological roles also remains to be clarified. To assess the possible physiological role of DNP in the salivary glands, I investigated the localization of DNP peptide in the rat salivary glands by immunohistochemistry and the binding sites for radiolabelled DNP in the rat salivary glands and oral mucosa using in vitro autoradiography. DNP immunoreactivity was widely distributed in the submandibular, sublingual and parotid glands, particularly in the ducts such as the intercalated and striated ducts, where atrial natriuretic peptide (ANP) was colocalized in consecutive sections, but not in acini. High density $^{125}I-DNP$ binding sites were localized in the epithelia of the tongue and hard palate, while low density binding sites for $^{125}I-DNP$ were also distributed in the submandibular, sublingual, and parotid glands. In the hard palate and tongue, the precise location of this binding was revealed on the basal and parabasal cells of the epithelia by emulsion microautoradiography. These results suggest that DNP may not only have a role in the salivary glands but also play a role in the regulation of growth in the oral epithelium, particularly in the hard palate and tongue.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2002.11a
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• pp.535-542
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• 2002

최근 IT 산업이 급성장하면서 화상 회의, 게임, 채팅 등에서의 아바타(avatar) 제어를 위한 자연스러운 인터페이스 기술이 요구되고 있다. 본 논문에서는 동적 윤곽선 모델(active contour models; snakes)을 이용하여 복잡한 배경이 있는 컬러 CCD 카메라 영상에서 얼굴과 눈, 입, 눈썹, 코 등의 얼굴 요소에 대해 윤곽선을 추출하거나 위치를 파악하는 방법을 제안한다. 일반적으로 스네이크 알고리즘은 잡음에 민감하고 초기 모델을 어떻게 설정하는가에 따라 추출 성능이 크게 좌우되기 때문에 주로 단순한 배경의 영상에서 정면 얼굴의 추출에 사용되어왔다 본 연구에서는 이러한 단점을 파악하기 위해, 먼저 YIQ 색상 모델의 I 성분을 이용한 색상 정보와 차 영상 정보를 사용하여 얼굴의 최소 포함 사각형(minimum enclosing rectangle; MER)을 찾고, 이 얼굴 영역 내에서 기하학적인 위치 정보와 에지 정보를 이용하여 눈, 입, 눈썹, 코의 MER을 설정한다. 그런 다음, 각 요소의 MER 내에서 1차 미분과 2차 미분에 근거한 내부 에너지와 에지에 기반한 영상 에너지를 이용한 스네이크 알고리즘을 적용한다. 이때, 에지 영상에서 얼굴 주변의 복잡한 잡음을 제거하기 위하여 색상 정보 영상과 차 영상에 각각 모폴로지(morphology)의 팽창(dilation) 연산을 적용하고 이들의 AND 결합 영상에 팽창 연산을 다시 적용한 이진 영상을 필터로 사용한다. 총 7명으로부터 양 눈이 보이는 정면 유사 방향의 영상을 20장씩 취득하여 총 140장에 대해 실험한 결과, MER의 오차율은 얼굴, 눈, 입에 대해 각각 6.2%, 11.2%, 9.4%로 나타났다. 또한, 스네이크의 초기 제어점을 얼굴은 44개, 눈은 16개, 입은 24개로 지정하여 MER추출에 성공한 영상에 대해 스네이크 알고리즘을 수행한 결과, 추출된 영역의 오차율은 각각 2.2%, 2.6%, 2.5%로 나타났다.해서 Template-based reasoning 예를 보인다 본 방법론은 검색노력을 줄이고, 검색에 있어 Feasibility와 Admissibility를 보장한다.매김할 수 있는 중요한 계기가 될 것이다.재무/비재무적 지표를 고려한 인공신경망기법의 예측적중률이 높은 것으로 나타났다. 즉, 로지스틱회귀 분석의 재무적 지표모형은 훈련, 시험용이 84.45%, 85.10%인 반면, 재무/비재무적 지표모형은 84.45%, 85.08%로서 거의 동일한 예측적중률을 가졌으나 인공신경망기법 분석에서는 재무적 지표모형이 92.23%, 85.10%인 반면, 재무/비재무적 지표모형에서는 91.12%, 88.06%로서 향상된 예측적중률을 나타내었다.ting LMS according to increasing the step-size parameter $\mu$ in the experimentally computed. learning curve. Also we find that convergence speed of proposed algorithm is increased by (B+1) time proportional to B which B is the number of recycled data buffer without complexity of computation. Adaptive transversal filter with proposed data recycling buffer algorithm could efficiently reject ISI of channel and increase speed of convergence in avoidance burden of computational complexity in reality when it was experimented having the same condition of

• Korean Journal of Fisheries and Aquatic Sciences
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• v.37 no.6
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• pp.445-454
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• 2004

A search for contraction and relaxation responses on the smooth muscles, antimicrobial and antioxidant activity in different body parts of 4 freshwater fish and 4 marine fish were conducted. The four freshwater fish studied were Sarotherodon niloticus (tilapia), Channa arus (snake head), Cyprinus carpio (Israel carp) and Siluru osotus (catfish), and the four marine fish were Scyliorhinus torazame (tiger shark), Ateiepus japonicus (tadpole fish), Mugil cephalus (gray mullet) and Thamnaconus modestus (file fish). Frozen samples were extracted with distilled water containing $1{\%}$ acetic acid. Antimicrobial activity against Bacillus subtilis and Eschrrichia coli was detected in extracts from several tissues in all species tested. Relatively high antimicrobial activity could also be detected in the bile extracts from C. carpio, M. cephalus, and T. modestus. Contraction and relaxation responses on smooth muscles could be detected in all species tested, especially in the intestine extracts. Antioxidant activity was also detected in extracts from several tissues in all species tested, while in the extracts from S. osotus, excluding livers and spleens, no antioxidant activity was detected. Results from this study suggest that fish are a potential source for the discovery of novel bioactive materials.

• Journal of KIISE:Software and Applications
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• v.27 no.7
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• pp.731-741
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• 2000

This paper proposes a method to detect a facial region and extract facial features which is crucial for visual recognition of human faces. In this paper, we extract the MER(Minimum Enclosing Rectangle) of a face and facial components using projection analysis on both edge image and binary image. We use an active contour model(snakes) for extraction of the contours of eye, mouth, eyebrow, and face in order to reflect the individual differences of facial shapes and converge quickly. The determination of initial contour is very important for the performance of snakes. Particularly, we detect Minimum Enclosing Rectangle(MER) of facial components and then determine initial contours using general shape of facial components within the boundary of the obtained MER. We obtained experimental results to show that MER extraction of the eye, mouth, and face was performed successfully. But in the case of images with bright eyebrow, MER extraction of eyebrow was performed poorly. We obtained good contour extraction with the individual differences of facial shapes. Particularly, in the eye contour extraction, we combined edges by first order derivative operator and zero crossings by second order derivative operator in designing energy function of snakes, and we achieved good eye contours. For the face contour extraction, we used both edges and grey level intensity of pixels in designing of energy function. Good face contours were extracted as well.

• Journal of Astronomy and Space Sciences
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• v.20 no.1
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• pp.83-94
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• 2003

Chon-Mun-Ryu-Cho (天文類抄), written (edited) by Lee Sun-Ji (李純之) during the period of King Se-Jong, is a representative astronomy book of Cho-Sun (朝鮮: A.D. 1392-1910) Dynasty. We find and study in the first page of the book; the description of 28 oriental constellations as a Sasin (four mythical oriental animals)-animal sky map which is not widely known yet. The map consists of four groups of constellations, each of which represents the Sasin: Chang-Ryong (蒼龍: dragon), Baek-Ho (白虎: tige.s with Ki-Rin [離隣: Oriental giraffe]), Ju-Jak (朱崔: Chinese phoenix), Hyun-Mu (玄武: a tortoise interwined with a snake). Each group (animals) spans 2 ～ 7 of 28 oriental constellations (宿). As we know from the illustration (論說) of the Chon-Sang-Yol-Cha-Bun-Ya-Ji-Do (天象列次分野之圖), a representative sky map of Cho-Sun Dynasty, astronomy in Cho-Sun Dynasty is closely related to that in Go- Gu-Rye. (高句麗: B.C. 37 -A.D. 668) Dynasty. Since these Sasin-animals appear in most mural paintings of Go-Gu-Rye. (高句麗) tombs, visualization of sky with these animal constellations could have been established as early as in Go-Gu-Ryer Dynasty. We also reconstruct this ”A Sasin-animal Korean sky map” based on the shapes of the Sasin and Ki-Rin from Go-Gu-Ryer paintings and 28 oriental constellations in Chon- S an g- Yol- C h a- B un- Ya- J i- Do.