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A Case Report of Coldness of Both Extremity Patient Using Conservative Korean Medical Treatment (사지말단의 냉감을 호소하는 수족냉증 환자 치험 1례)

  • Kim, Gyeong-muk;Jung, Min-ho;Son, Jung-hwa;Jung, Woo-sang;Mun, Sang-Kwan;Kwon, Seungwon;Cho, Ki-ho
    • The Journal of the Society of Stroke on Korean Medicine
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    • v.18 no.1
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    • pp.37-45
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    • 2017
  • A case of a 66-year-old Korean male with coldness of both extremity that ruled out another mechanical and endocrinologic problem is presented. He was treated with acupuncture, electroacupuncture and herbal medicine - 十全大補湯(Sipjundaebo-tang, Juzentaihoto) and 柴胡桂枝乾薑湯(Sihogyejigungang-tang, Saikokeishikankyouto). We used SF-MPQ grading scale to assess severity of patient's symptom and DITI to measure patient's temperature. After Korean medical treatment, there was improvement in subjective symptom of patient and gap of lower extremity temperature. Korean medical treatment may be effective in treating coldness patients.

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Effects of Ovarian Status at the Time of Initiation of the Modified Double-Ovsynch Program on the Reproductive Performance in Dairy Cows

  • Jaekwan Jeong;Illhwa Kim
    • Journal of Veterinary Clinics
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    • v.40 no.3
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    • pp.238-241
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    • 2023
  • This study determined the effect of ovarian status at the beginning of the modified Double-Ovsynch program on reproductive performance in dairy cows. In the study, 1,302 cows were treated with a modified Double-Ovsynch program at 56 days after calving. This program comprises administering gonadotropin-releasing hormones (GnRH), prostaglandin F (PGF) 10 days later, GnRH 3 days later, GnRH 7 days later, and GnRH 56 h later, followed by timed artificial insemination (TAI) 16 h later. At the beginning of the program, cows were categorized according to the size of the largest follicle and the presence of a corpus luteum (CL) in the ovaries as follows: 1) small follicle (<5 mm, SF group, n = 100), 2) medium follicle (8-20 mm, MF group, n = 538), and 3) large follicle (≥25 mm, LF group, n = 354) without a CL, or 4) the presence of a CL (CL group, n = 310). The pregnancies per AI after the first TAI were analyzed by logistic regression using the LOGISTIC procedure, and the logistic model included the fixed effects of the herd size, parity, body condition score (BCS) at the first TAI, TAI period, and ovarian status. A larger herd size, higher BCS at the first TAI, and TAI period with no heat stress increased (p < 0.05) the probability of pregnancy per AI after the first TAI. However, ovarian status at the beginning of the program did not affect (p > 0.05) the pregnancies per AI (ranges of 37.9% to 42.9%). These results show that the modified Double-Ovsynch program can be used effectively while maintaining good fertility regardless of the ovarian status in dairy herds.

A Randomized Trial Comparing the Effect of Unani Formulation with Metronidazole in Bacterial Vaginosis

  • Nazia Usmoni;Mariyam Roqaiya;Mohd Aqil Quadri;Arshiya Sultana;Taseen Banu;Sumbul Alam
    • CELLMED
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    • v.13 no.14
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    • pp.18.1-18.13
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    • 2023
  • Background and objectives: Bacterial vaginosis (BV) is recognized as the most prevalent type of vaginal infection, impacting approximately 19-24% of women in their reproductive years. The recurrence rate of BV is significant, negatively impacting the well-being of affected women. This study aimed to compare the therapeutic effects of a polyherbal Unani formulation and metronidazole in treating bacterial vaginosis. Methodology: In this prospective patient blinded standard controlled trial, a total of 40 individuals with a clinical diagnosis of bacterial vaginosis were randomly assigned to receive either an active control treatment (n = 20) or a test drug (n = 20). In the test drug combination of Acacia catechu, Azadirachta indica and Quercus infectoria in tablet (1g) form in the dose of 2 tablets orally twice daily with water was administered for 3 weeks. In the active control standard drug, metronidazole 400 mg tablet, orally twice daily was given for one week. The primary outcome measure was clinical cure; H. negative Amsel's criteria and a reduction in subjective symptoms, while the secondary outcome measure was an improvement in SF-36 quality of life (QOL). Results and conclusion: Both the experimental treatment and the metronidazole demonstrated a significant clinical cure for bacterial vaginosis as well as an increase in health-related quality of life. Based on these findings, it appears that the test medication is a potent Unani formulation for the treatment of bacterial vaginosis. A well conducted trial with a bigger sample size is required to corroborate these findings.

Analysis and study of Deep Reinforcement Learning based Resource Allocation for Renewable Powered 5G Ultra-Dense Networks

  • Hamza Ali Alshawabkeh
    • International Journal of Computer Science & Network Security
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    • v.24 no.1
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    • pp.226-234
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    • 2024
  • The frequent handover problem and playing ping-pong effects in 5G (5th Generation) ultra-dense networking cannot be effectively resolved by the conventional handover decision methods, which rely on the handover thresholds and measurement reports. For instance, millimetre-wave LANs, broadband remote association techniques, and 5G/6G organizations are instances of group of people yet to come frameworks that request greater security, lower idleness, and dependable principles and correspondence limit. One of the critical parts of 5G and 6G innovation is believed to be successful blockage the board. With further developed help quality, it empowers administrator to run many systems administration recreations on a solitary association. To guarantee load adjusting, forestall network cut disappointment, and give substitute cuts in case of blockage or cut frustration, a modern pursuing choices framework to deal with showing up network information is require. Our goal is to balance the strain on BSs while optimizing the value of the information that is transferred from satellites to BSs. Nevertheless, due to their irregular flight characteristic, some satellites frequently cannot establish a connection with Base Stations (BSs), which further complicates the joint satellite-BS connection and channel allocation. SF redistribution techniques based on Deep Reinforcement Learning (DRL) have been devised, taking into account the randomness of the data received by the terminal. In order to predict the best capacity improvements in the wireless instruments of 5G and 6G IoT networks, a hybrid algorithm for deep learning is being used in this study. To control the level of congestion within a 5G/6G network, the suggested approach is put into effect to a training set. With 0.933 accuracy and 0.067 miss rate, the suggested method produced encouraging results.

Detection of Potential Flow Paths of Leaked CO2 from Underground Storage Using Electrical Resistivity Survey (전기비저항탐사 방법에 의한 지중 저장 이산화탄소 누출 가능 경로 탐지)

  • Lim, Woo-Ri;Hamm, Se-Yeong;Hwang, Hak-Soo;Kim, Sung-Wook;Jeon, Hang-Tak
    • The Journal of Engineering Geology
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    • v.28 no.1
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    • pp.69-79
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    • 2018
  • The Korean government attempts to reduce $CO_2$ emissions by 37% to 314.7 Mt $CO_2$, down from the estimated 850.6 Mt $CO_2$ until 2030 in order to confront green house effect. In this context, in 2014, Korean government launched $CO_2$ Storage Environmental Management Research (K-COSEM) Center for carrying out pilot-scale research on $CO_2$ leakage from underground $CO_2$ storage facilities. For the detection of $CO_2$ leakage, it is necessary to identify hydrologeological and geophysical characteristics of the subject area. In the study site of Naesan-ri, Daeso-myeon, Eumseong-gun, Chungbuk Province, two times injection tests (June 28-July 24, 2017 and August 07-September 11, 2017) of $CO_2$ and $SF_6$ dissolved waters, respectively, was conducted to understand the leakage behavior of $CO_2$ from underground. The injection well was drilled to a depth of 24 m with a 21-m casing and screen interval of 21~24 m depth. Two times resistivity surveys on August 18, 2017 and September 1, 2017, were conducted for revealing the flow of the injected water as well as the electrical properties of the study site. The study results have shown that the high-resistivity zone and the low-resistivity zone are clearly contrasted with each other and the flow direction of the injected water is similar to natural groundwater flow. Besides, the low resistivity zone is widely formed from the depth of injection to the shallow topsoil, indicating that the weathered zone of high permeability has high $CO_2$ leakage potential.

Narrative Composition and Visual Representation of Alternative History in FPS Game Trailer -By focusing on (FPS 게임 트레일러 속 대체 역사적 서사구성과 시각적 재현 - <울펜슈타인: 더 뉴 오더>를 중심으로)

  • Choi, Do-Won;Lee, Hyun-Seok
    • Cartoon and Animation Studies
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    • s.41
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    • pp.253-277
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    • 2015
  • When was launched in 2014, it was immediately ranked 2nd in English gross sales record in the first half of 2014, attracting huge attention from avid game users. Colin Moriarty(2014) states that the worldwide popular game, , lies on the alternative history assumption, 'what if Nazi Germany won the second world war? In regard to this, this research addresses how the characteristics of alternative history was adopted and visually represented in FPS game trailer. In terms of research method, firstly, literatures will be reviewed about definition of alternative history and some of the previous examples where alternative history was applied in novels, films and games. Secondly, narrative composition of alternative history is categorized as three sequential phases, (1) borrowing real history material, (2) connection between real and fictional history and (3) reconstruction of history through reinterpretation. Thirdly, the live-action game trailer will be analysed by three sequential phases of narrative composition, and CG game character and background will be analysed by spatial background, characters and props. The phase of 'borrowing' has used the historic images related to the World War II, and the phase of "connection' has composited by "connection through circumstantial events". The phase of 'reconstruction' has unfolded its fictional narrative in the form of "limited fictional history" In addition to this, has constructed dystopia world through composing of historic images and CG characters by SF design. In the light of this, the narrative composition of alternative history successfully extends to game area.

Children's and Young Adult Literature in Library and Information Science Departments in the Republic of Korea: A Study of the Current State of Education and Suggestions for Future Directions (한국 문헌정보학 교과과정에서의 어린이청소년 문학 교육 현황 및 개선 방안 연구)

  • Yeojoo Lim
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.34 no.4
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    • pp.303-329
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    • 2023
  • This study aimed to investigate the current state and suggest future directions of children's and young adult literature education in Library and Information Science(LIS) departments in Korean universities. Courses related to children's and young adult literature in 34 LIS departments in Korea were investigated, and in-depth interviews and surveys were conducted with professors and instructors who have experience teaching courses related to children's and young adult literature in LIS departments. The results show there are on average 1.7 courses related to children's and young adult literature in undergraduate programs. 36% of schools had less than one course related to children's and young adult literature, and most of them were Reading Guidance courses. 83%(24 out of 29 people)of the survey participants said they teach children's and young adult literature in their classes. The professors and instructors spent the most of their lecture time on picture books. They spent the minimum time on genres such as SF, Fantasy, and manhwa. Lack of time to teach so many things in short 16 weeks made them feel rushed and distressed. Some survey respondents regarded themselves as non-experts in children's and young adult literature, even though they had competency in that field, which shows the general atmosphere in the LIS field that LIS people are not qualified enough to be experts in children's literature. All interviewees and some survey respondents insisted children's and young adult literature education in the LIS departments should be practical. Professors and instructors tried their best to incorporate diverse teaching methods, including discussions, storytelling, writing reviews, so their students can acquire proper knowledge on children's and young adult library services.

Shoot Proliferation and Plant Regeneration from Suspension-Cultured Cells of Dianthus gratianopol (패랭이꽃속 Dianthus gratianopol의 현탁배양세포로부터 Shoot 증식과 식물체 재분화)

  • Kim Joon-Chul
    • Journal of Plant Biotechnology
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    • v.32 no.4
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    • pp.301-306
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    • 2005
  • Conditions for efficient organogenesis and plant regeneration from Dianthus gratianopol suspension cultured cells were established. Shoot-forming calli of glossy surface, pale green and knobby type were selected from leaf explant-derived calli and were suspension-subcultured every week in CP liquid medium with 1.0 mg/L 2,4-D and 0.5 mg/L BAP. Combinations of 1.0 mg/L 2,4-D and 0.5 mg/L BAP, and 1.5 mg/L 2,4-D and 0.5 mg/L BAP were effective for the induction of regenerative callus from the suspension cultured cell clusters. Multiple shoot primordia were initiated from the green spots of these regenerative callus and formed shoots on MS medium with 1.0 mg/L TDZ and 0.5 mg/L PAA. Shoot regeneration frequency (calli regenerating at least one shoot) was about 87%. For plant regeneration, proliferated shoots were excised and transferred to MS medium with 0.1 mg/L NAA for root initiation after 9 weeks of culture. The regenerants were potted in soil and formed the flowering buds and petals. Also, adventitious shoots were formed from the excised green shoot primordia of regenerative callus and these shoots proliferated successfully and regenerated to whole plants.

Characterization of Homocysteine ${\gamma}$-Lyase from Submerged and Solid Cultures of Aspergillus fumigatus ASH (JX006238)

  • El-Sayed, Ashraf S.;Khalaf, Salwa A.;Aziz, Hani A.
    • Journal of Microbiology and Biotechnology
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    • v.23 no.4
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    • pp.499-510
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    • 2013
  • Among 25 isolates, Aspergillus fumigatus ASH (JX006238) was identified as a potent producer of homocysteine ${\gamma}$-lyase. The nutritional requirements to maximize the enzyme yield were optimized under submerged (SF) and solid-state fermentation (SSF) conditions, resulting in a 5.2- and 2.3-fold increase, respectively, after the last purification step. The enzyme exhibited a single homogenous band of 50 kDa on SDS-PAGE, along with an optimum pH of 7.8 and pH stability range of 6.5 to 7.8. It also showed a pI of 5.0, as detected by pH precipitation with no glycosyl residues. The highest enzyme activity was obtained at $37-40^{\circ}C$, with a $T_m$ value of $70.1^{\circ}C$. The enzyme showed clear catalytic and thermal stability below $40^{\circ}C$, with $T_{1/2}$ values of 18.1, 9.9, 5.9, 3.3, and 1.9 h at $30^{\circ}C$, $35^{\circ}C$, $40^{\circ}C$, $50^{\circ}C$, and $60^{\circ}C$, respectively. Additionally, the enzyme $K_r$ values were 0.002, 0.054, 0.097, 0.184, and 0.341 $S^{-1}$ at $30^{\circ}C$, $35^{\circ}C$, $40^{\circ}C$, $50^{\circ}C$, and $60^{\circ}C$, respectively. The enzyme displayed a strong affinity to homocysteine, followed by methionine and cysteine when compared with non-S amino acids, confirming its potency against homocysteinuria-related diseases, and as an anti-cardiovascular agent and a specific biosensor for homocysteinuria. The enzyme showed its maximum affinity for homocysteine ($K_m$ 2.46 mM, $K_{cat}\;1.39{\times}10^{-3}\;s^{-1}$), methionine ($K_m$ 4.1 mM, $K_{cat}\;0.97{\times}10^{-3}\;s^{-1}$), and cysteine ($K_m$ 4.9 m M, $K_{cat}\;0.77{\times}10^{-3}\;s^{-1}$). The enzyme was also strongly inhibited by hydroxylamine and DDT, confirming its pyridoxal 5'-phosphate (PLP) identity, yet not inhibited by EDTA. In vivo, using Swiss Albino mice, the enzyme showed no detectable negative effects on platelet aggregation, the RBC number, aspartate aminotransferase, alanine aminotransferase, or creatinine titer when compared with negative controls.

Pattern of Nutrient Fluxes in Deciduous Forest Ecosystem Imparted by Acidic Deposition (산성강하물 조건하에서 활엽수림 생태계의 양료순환 양상)

  • Chang, Kwan-Soon
    • Korean Journal of Environment and Ecology
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    • v.15 no.3
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    • pp.230-236
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    • 2001
  • The fluxes of wet deposition(WD), throughfall(TF), stemflow(SF) and soil leachates were measured to understand base cation budgets on deciduous ecosystem impacted by acidic deposition in the north-western part of Tomakomai in Hokkaido, Japan. The flux of $H^{+}$ for wet deposition was $0.34kmo1_{c}$ $ha^{2+}$ and the flux of base cation, $K^{+}$ /, Na$^{ + }$, $Ca^{2+}$ and $Mg^{2+}$ far throughfall plus stemflow wart 1.6 kmolc $ha^{-1}$ , 3 times higher level than that for wet deposition. The flux of base cation for canopy leaching(LI) was 0.95 kmolc ha$^{-1}$ , 2.8 times higher level than $H^{+}$ sources in wet deposition. The major mechanism of $^{+}$ consumption closely related to acidic neutralizing capacity of canopy. The ionic flux for soil leachates from Boil reservoir and proton consumption in soil was dependent on soil chemical states and exchangeable Ca in soil had a major factor of H$^{+ }$ consumption. The base cation budgets on deciduous ecosystem showed positive balance fur Na, Ca and Mg, while K was the negative value.

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