• 대한의생명과학회지
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• 제10권4호
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• pp.325-332
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• 2004

Inflammatory factor such as Interleukin-1 play important roles in determining the fate of both acute and chronic neurological disorders. We investigated whether inhibitors of PKC or PTK can serve as pharmacological agents to reduce IL-I production and the mechanisms underlying their pharmacological effects in a mixed population of glia. Inhibitors of PKC such as H7, Go6976 and Ro31-8220 significantly reduced both the mRNA and protein levels of IL-1α and IL-β in lipopolysaccharide-activated primary glial cells. While the PTK inhibitor genistein also significantly reduced the production of these cytokines, it did not affect the expression of their mRNA. Taken together, inhibitors of PKC and PTK could serve as pharmacological agents to reduce IL-1 production. However, the mechanisms underlying their pharmacological effects are different. Our results provide evidence that inhibitors of protein kinases can serve as pharmacological agents to modulate IL-1 production in glial cell, and in turn, alleviate neuronal injury.

• 한국경영과학회지
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• 제39권2호
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• pp.67-82
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• 2014

The purpose of this study is two-fold : the one is to examine the causal relationship between domestic large firms' win-win growth effort and their financial performance by fiscal years; and the other is to develop a quantitative win-win growth index to overcome the limitation of the current one mainly using a survey method developed by NCCP (National Commission for Corporate Partnership). To serve the first purpose, we take a sample of 128 large companies whose win-win growth indices as of year 2011 and 2012 were evaluated by NCCP. We use their respective fiscal year's financial data to select 62 candidate financial ratios, which are then used in subsequent empirical tests. For the tests, we employ ordered probit model with stepwise selection method and two-way ANOVA with randomized block design to identify which of the 62 financial ratios are statistically significant ones to affect the firms' win-win growth index as well as to determine if the firms' win-win growth effort would cause their financial performance positively. To serve the second purpose, we devise a model using the 123 firms' 45 financial ratios, which employs ordered probit model with stepwise selection, and the validation of the model follows. We claim that the model suggested in this study serve as an alternative complementing the current one as it can produce the index in a more objective and swift manner using the firms' publicized financial statements.

• 한국지능시스템학회논문지
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• 제15권5호
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• pp.567-572
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• 2005

최근 컴퓨터의 소형화와 인터넷의 대중화와 함께 유비쿼터스 컴퓨팅도 많은 주목을 받고 있다. 언제 어디서나 원하는 서비스를 제한 없이 받을 수 있는 유비쿼터스 시대가 도래하면서 유비쿼터스 환경을 어떻게 제시하고, 어떤 서비스와 이용 방법을 사용자에게 어떻게 제공할 것인지가 중요해 지고 있다. 본 논문에서는 유비쿼터스 환경에서 지능 에이전트를 사용하여 사용자의 목적에 가장 적합한 장치가 구성할 수 있도록 하는 방법을 제안하였다. 검색 에이전트가 주변 장치들을 검색하여 기능별 목록을 작성하고 서버로 전송하면 서버는 전송 받은 정보를 지능 시스템을 통하여 학습하게 된다. 즉, 사용자가 목록에 따라 언어 항으로 작업 정보를 입력하면 서버가 작업 환경에 적합한 시스템을 선택하고, IP 어드레스를 이용하여 시스템을 구성하도록 하였다. 이것을 응용 예를 통하여 구현하고 실험을 통해 확인하였다.

• Nuclear Engineering and Technology
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• 제54권7호
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• pp.2491-2509
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• 2022

As an important device in the nuclear island, the nuclear coolant pump can continuously provide power for medium circulation. The vane is one of the stationary parts in the nuclear coolant pump, which is installed between the impeller and the casing. The shape of the vane plays a significant role in the pump's overall performance and stability which are the important indicators during the safety serve process. Hence, the bionic concept is firstly applied into the design process of the vane to improve the performance of the nuclear coolant pump. Taking the scaled high-performance hydraulic model (on a scale of 1:2.5) of the coolant pump as the reference, a united bionic design approach is proposed for the unique structure of the guide vane of the nuclear coolant pump. Then, a new optimization design platform is established to output the optimal bionic vane. Finally, the comparative results and the corresponding mechanism are analyzed. The conclusions can be gotten as: (1) four parameters are introduced to configure the shape of the bionic blade, the significance of each parameter is herein demonstrated; (2) the optimal bionic vane is successfully obtained by the optimization design platform, the efficiency performance and the head performance of which can be improved by 1.6% and 1.27% respectively; (3) when compared to the original vane, the optimized bionic vane can improve the inner flow characteristics, namely, it can reduce the flow loss and decrease the pressure pulsation amplitude; (4) through the mechanism analysis, it can be found out that the bionic structure can induce the spanwise velocity and the vortices, which can reduce drag and suppress the boundary layer separation.

• 영어영문학
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• 제56권3호
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• pp.501-517
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• 2010

This paper examines the British imperialism found in Edith Nesbit's fantasy stories by looking at the function of magic and of the hierarchical relationships seen in the books. Although Edith Nesbit is relatively unknown in Korea, she is widely recognized as having had a great influence on the 20th century British literary world, and is also well-known for her political position as a socialist. Nesbit's fantasy books are commonly differentiated from other Victorian children's books written before her in that she created realistic and liberal children characters and rejected the adult didactic tone. While Nesbit's books have been recognized as revolutionary and being distinguished from other Victorian children's books, I suggest that the ideas found in her fantasy novels largely include the dominant Victorian message of British imperialism. This imperial ideology is delivered by the logic of magic and the multilateral hierarchies. The two magic creatures (The Psammead and the Phoenix) and the two magic items from an Oriental background (the Carpet and the Amulet) all have a magic power to grant people's wishes, wholeheartedly exercising their power and knowledge for the sake of the British characters. While the magic agents serve to fulfill the children's wishes, the children aim to please their parents and to benefit their family, showing layered hierarchies among the characters. Also, there is a hierarchical distinction between the magic items and the magic creatures in that the magic items have no voice to express themselves but only serve and obey the British children. The foreign characters that the children encounter in their adventures also cooperate with the British characters to help them to fulfill their goals. In short, magic frees the children from the adult-centered world but ultimately their free adventures serve their parents and other adults, and represent the ideals and hierarchical concepts of British imperialism. Thus, Nesbit's position as a modern writer seems to be ambiguous, switching between modern characterization and style, and the old Victorian imperial messages that also exist in her fantasy novels.

• 서비스연구
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• 제7권3호
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• pp.105-118
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• 2017

본 연구는 서비스경제의 발전을 이끌어갈 기본 철학을 탐구하였다. 한국고유사상이 서비스경제 철학에 부합하며, 한국고유사상의 발현을 통해 서비스문화가 확산되고 서비스경제가 활성화될 수 있음을 제시하였다. 서비스경제는 서비스라는 관계재화가 중심이 되므로, 실체성을 강조하는 서양철학보다 관계성을 강조하는 동양철학이 서비스경제 철학으로서 더 부합한다고 할 수 있다. 음양 또는 천지의 2태극 사상은 서비스경제에서 중심으로 부상된 인간의 역할을 강조하고 있지 않으므로, 인간을 중시하는 새로운 철학이 요구된다. 천지(음양)의 양극 구조 철학을 뛰어넘는 천지인 3태극 구조의 한국 고유 사상이 서비스경제시대, 제4차 산업혁명시대에는 인류사회와 경제의 발전을 견인하는 중심철학이 될 수 있다. 천지인 3재의 본성은 조화성, 수평성, 쌍방향성, 관계성 등의 서비스본질과도 부합하므로 천지인 3태극 사상은 서비스경제시대의 기본 철학이 될 수 있다. 인간이 하늘과 땅의 주관자 및 주도자로서 역할을 하는 사상이 현대 서비스경제에서 경영자와 종업원 및 소비자인 사람이 창조자로서 중심역할을 하는 구조와 부합한다. 따라서, 한국고유사상은 서비스경제를 이끌어갈 사상적 기반으로서 정합되며, 서비스경제를 육성시킬 수 있는 철학적 프레임이 된다.

• 도서관문화
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• 제16권8호
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• pp.13-16
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• 1975

본 기사는 Josephine Riss Fang 교원가 Chinese Libraries Carry Out Chairman Mao's Dictum : 'Serve the Reople'이란 표제로 Wilson Library Bulletin, vol. 49(June 1975), p.774-749에 기고한 것을 우리 말로 옮긴 것이다. Fang교원는 오스트리아 태생으로 현재 미국 보스턴에 있는 시몬즈대학의 도서관학교원로 재직중에 있다.

• 한국수학사학회지
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• 제15권3호
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• pp.49-58
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• 2002

The present paper aims to show basic substitution between metaphysics and mathematical abstraction in the philosophy of mathematics. The general troths of metaphysics and the truths particularly relevant to tile nature of mathematical abstraction serve as speculative guides in ordering the content and discussing the nature of the multiple questions which lie between the disputed frontiers of metaphysics and mathematical abstraction.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2013년도 춘계학술대회 논문집
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• pp.823-824
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• 2013

• Nuclear Engineering and Technology
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• 제30권1호
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• pp.75-82
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• 1998

Development and implementation of food irradiation was driven by needs pertaining to food safety improvement, food spoilage reduction, and quarantine/trade. The need for food safety is caused by the increasing morbidity and mortality caused by food-borne diseases worldwide, and it affects national economy and world-trade. Radiation technology can serve to ameliorate the vulnerability of our food supply system.