• Molecules and Cells
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• 제28권6호
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• pp.553-558
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• 2009

In the periphery, a galectin-1 receptor, CD7, plays crucial roles in galectin-1-mediated apoptosis of activated T-cells as well as progression of T-lymphoma. Previously, we demonstrated that $NF-{\kappa}B$ downregulated CD7 gene expression through the p38 MAPK pathway in developing immature thymocytes. However, its regulatory pathway is not well understood in functional mature T-cells. Here, we show that CD7 expression was downregulated by Twist2 in Jurkat cells, a human acute T-cell lymphoma cell line, and in EL4 cells, a mature murine T-cell lymphoma cell line. Furthermore, ectopic expression of Twist2 in Jurkat cells reduced galectin-1-induced apoptosis. While full-length Twist2 decreased CD7 promoter activity, a C-terminal deletion form of Twist2 reversed its inhibition, suggesting an important role of the C-terminus in CD7 regulation. In addition, CD7 expression was enhanced by histone deacetylase inhibitors such as trichostatin A and sodium butyrate, which indicates that Twist2 might be one of candidate factors involved in histone deacetylation. Based on these results, we conclude that upregulation of Twist2 increases the resistance to galectin-1-mediated-apoptosis, which may have significant implications for the progression of some T-cells into tumors such as Sezary cells.

• 대한수학회보
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• 제53권2호
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• pp.601-614
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• 2016

Let $N_{g,s}$ denote the nonorientable surface of genus g with s boundary components. Recently Paris and Szepietowski [12] obtained an explicit finite presentation for the mapping class group $\mathcal{M}(N_{g,s})$ of the surface $N_{g,s}$, where $s{\in}\{0,1\}$ and g + s > 3. Following this work, we obtain a finite presentation for the subgroup $\mathcal{T}(N_{g,s})$ of $\mathcal{M}(N_{g,s})$ generated by Dehn twists.

• 한국운동역학회지
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• 제28권2호
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• pp.69-78
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• 2018

Objective: The purpose of this study was to investigate the feasibility of a new vault technique through a kinematic comparison of the YANG Hak Seon and Yeo 2 vaults. Method: The photographic images of the YANG Hak Seon and Yeo 2 vaults were collected using a high-speed camera, and their kinematic characteristics were analyzed using three-dimensional image analysis. Results: During the post-flight phase of the Yeo 2 and YANG Hak Seon vaults, the time of flight, height of flight, and flight distance were similar. At the peak of the post-flight phase, the trunk rotation angle of the YANG Hak Seon vault rotated $457^{\circ}$ more than did the Yeo 2 vault. During the post-flight descending period, the twist velocity of the trunk was much faster with the YANG Hak Seon vault ($1,278^{\circ}/s$) than with the Yeo 2 vault ($1,016^{\circ}/s$). Conclusion: To succeed in the new technique, the average twist velocity during post-flight must be maintained at $1,058^{\circ}/s$ and the twist velocity must be increased from the ascending phase.

• Journal of Computational Design and Engineering
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• 제3권3호
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• pp.215-225
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• 2016

In recent years, the automotive industry has known a remarkable development in order to satisfy the customer requirements. In this paper, we will study one of the components of the automotive which is the twist beam. The study is focused on the multicriteria design of the automotive twist beam undergoing linear elastic deformation (Hooke's law). Indeed, for the design of this automotive part, there are some criteria to be considered as the rigidity (stiffness) and the resistance to fatigue. Those two criteria are known to be conflicting, therefore, our aim is to identify the Pareto front of this problem. To do this, we used a Normal Boundary Intersection (NBI) algorithm coupling with a radial basis function (RBF) metamodel in order to reduce the high calculation time needed for solving the multicriteria design problem. Otherwise, we used the free form deformation (FFD) technique for the generation of the 3D shapes of the automotive part studied during the optimization process.

• 한국염색가공학회지
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• 제12권2호
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• pp.89-95
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• 2000

Effect of twist-setting time, temperature and cylinder layer for the physical properties of the twist yarn were investigated by separated 9 layer from yarn cylinder. Obtained results were as follow. Shrinkage of the yarn in middle layer shows high value with heat-permeation and in inner's shows low value because of cylinder hardness. And then yarn thermal shrinkage in outer layers shows more or less high value because twist yarn in the outer layer sets more faster. Concerning to the difference on the yam physical properties among cylinder layers, the changes on physical properties shows significant differences from the 7th layer to the last one. Linear density, T.P.M and initial modulus decreases but snarl index increases.

• International Journal of Control, Automation, and Systems
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• 제5권1호
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• pp.24-34
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• 2007

Closed-loop active twist control of integral helicopter rotor blades is investigated in this paper for reducing hub vibration induced in forward flight. A four-bladed fully articulated integral twist-actuated rotor system has been designed and tested successfully in wind tunnel in open-loop actuation. The integral twist deformation of the blades is generated using active fiber composite actuators embedded in the composite blade construction. An analytical framework is developed to examine integrally twisted helicopter blades and their aeroelastic behavior during different flight conditions. This aeroelastic model stems from a three-dimensional electroelastic beam formulation with geometrical-exactness, and is coupled with finite-state dynamic inflow aerodynamics. A system identification methodology that assumes a linear periodic system is adopted to estimate the harmonic transfer function of the rotor system. A vibration minimizing controller is designed based on this result, which implements a classical disturbance rejection algorithm with some modifications. Using the established analytical framework, the closed-loop controller is numerically simulated and the hub vibratory load reduction capability is demonstrated.

• 한국운동역학회지
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• 제13권3호
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• pp.81-98
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• 2003

The purpose of this study is to closely examine kinematic characteristics by jump phase of Li Xiaopeng motion in horse vaulting and provide the training data. In doing so, as a result of analyzing kinematic variables through 3-dimensional cinematographic using the high-speed video camera to Li Xiaopeng motion first performed at the men's vault competition at the 14th Busan Asian Games, the following conclusion was obtained. 1. It was indicated that at the post-flight, the increase of flight time and height and twisting rotational velocity has a decisive effect on the increase of twist displacement. And Li Xiaopeng motion showed longer flight time and higher flight height than Ropez motion with the same twist displacement of entire movement. Also the rotational displacement of the trunk at peak of COG was much short of $360^{\circ}$(one rotation) but twist displacement showed $606^{\circ}$. Likewise, Li Xiaopeng motion was indicated to concentrate on twist movement in the early flight. 2. It was indicated that at the landing, Li Xiaopeng motion gets the hip to move back, the trunk to stand up and the horizontal velocity of COG to slow down. This is thought to be the performance of sufficient landing, resulting from large security of rotational displacement of airborne and twist displacement. 3. It was indicated that at the board contact, Li Xiaopeng motion made a rapid rotation uprighting the trunk to recover slowing velocity caused by jumping with the horse in the back, and has already twisted the trunk nearly close to $40^{\circ}$ at board contact. Under the premise that elasticity is generated without the change of the feet contacting the board, it will give an aid to the rotation and twist of pre-flight. Thus, in the round-oH phase, the tap of waist according to the fraction and extension of hip joint and arm push is thought to be very important. 4. It was indicated that at the pre-flight, Li Xiaopeng motion showed bigger movement than the techniques of precedented studies rushing to the horse, and overcomes the concern of relatively low power of jump through the rapid rotation of the trunk. Li Xiaopeng motion secured much twist distance, increased rotational distance with the trunk bent forward, resulting in the effect of rushing to the horse. 5. At horse contact, Li Xiaopeng motion makes a short-time contact, and maintains horse take-off angle close to vertical, contributing to the increase of post-flight time and height. This is thought to be resulted from rapid move toward movement direction along with the rotational velocity of trunk rapidly earned prior to horse contact, and little shave of rotation axis according to twist motion because of effective twist in the same direction.

• 한국염색가공학회지
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• 제20권2호
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• pp.47-52
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• 2008

Nylon textured yarn is usually manufactured by disk type false twist texturing. Dyeing properties of nylon textured yam have not been studied yet. In this study, dyeing properties of nylon textured yam according to draw ratio out of process parameters were investigated. The fact that microstructure of nylon textured yarn in amorphous region particularly is transformed by draw ratio was confirmed indirectly by measurement of dyeing rate because dyeing rate was affected by the structure of amorphous region. Dyeing rate at draw ratio 1.29 was the lowest because the higher draw ratio increase amorphous orientation and disturb dye diffusion into amorphous region. The microstructure according draw ratio was indirectly confirmed by 5% strength, tenacity, elongation. But difference in K/S value and fastness was insignificant.

• 소성∙가공
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• 제12권8호
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• pp.718-723
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• 2003

Tn order to develop springback control technology for high-strength steel sheets, several studies have been conducted: dome stretching test, stepped s-rail forming and springback measurement, and optimally shaped initial blank design. First, to find out the formability of TRIP60, dome stretching test was performed. Next, the stepped s-rail die, which was designed to form a channel type panel with large twist and wall curl, was manufactured and used to evaluate the effect of controlling forming variables, such as blank holding force and flange amount on the springback. Furthermore, new measurement method of the springback was introduced to define wall curl and twist in geometrically complex panels. Finally, the optimally shaped initial blank was employed to verify one of the best ways to control the springback in channel type. high-strength sheet panels.

• 한국기계가공학회지
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• 제11권2호
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• pp.79-84
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• 2012

This study consist of two parts. One is development of a self-propelling vinyl remover which was already reported at the previous paper. This is the second part of the study. For the study, an attached vinyl remover was developed. It was consisted of connecting tractor to bucket, removing bucket from tractor, and the process was the tractor's assistance hydraulics. In the case of an attached vinyl remover, the vinyl was twisted 0.5times per 30~85cm length. The bobbin's diameter was 190mm and it's stable travelling speed was 1m/s. The revolution of the remover wheel was 90rpm to maintain the wheel's linear velocity. As seen at performance test at the field which had 950mm ridge intervals and 10 a area, the average working speed was 1m/s and the turning time was 20seconds. Therefore, the working performance was 24.5min/10a. The efficiency of used vinyl remover was 97% and working conditions were good.