• Analytical Science and Technology
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• v.19 no.6
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• pp.455-459
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• 2006

The extraction and separation of glabridin from licorice root by HPLC was performed in this work. First, by investigating the different extraction solvents, extraction methods and extraction times, a one-hour ultrasonic extraction procedure with ethyl acetate as the extraction solvent was optimized. Then the ethyl acetate extraction was applied to RP-HPLC for separation of glabridin. The column efficiencies and resolutions were experimentally investigated with different mobile phase compositions. Baseline separation of glabridin was obtained under the mobile phase composition of 50/50 vol.% (ACN/water). The retention time of glabridin was 20.3 min. The peak of glabridin was collected from the HPLC elution for several times and identified by LC/MS. Under the optimum extraction and HPLC separation methods, 1.26 g of glabridin per kg licorice root could be extracted.

• Journal of Korean Institute of Industrial Engineers
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• v.27 no.4
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• pp.406-412
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• 2001

IP address lookup is to determine the next hop destination of an incoming packet in the router. The address lookup is a major bottleneck in high performance router due to the increased routing table sizes, increased traffic, higher speed links, and the migration to 128 bits IPv6 addresses. IP lookup time is dependent on data structure of lookup table and search scheme. In this paper, we propose a new approach to build a lookup table that satisfies the memory constraint. The design of lookup table is formulated as an optimization problem. The objective is to minimize average depth from the root node for lookup. We assume that the frequencies with which prefixes are accessed are known and the data structure is level compressed trie with branching factor $\kappa$ at the root and binary at all other nodes. Thus, the problem is to determine the branching factor k at the root node such that the average depth is minimized. A heuristic procedure is proposed to solve the problem. Experimental results show that the lookup table based on the proposed heuristic has better average and the worst-case depth for lookup.

• Korean Journal of Medicinal Crop Science
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• v.10 no.4
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• pp.243-248
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• 2002

The effects of basal media, carbon, nitrogen, phosphate and some major macro elements on growth and shikonin production in Lithospermum erythrorhizon hairy root culture were studied. Among examined media, growth of hairy root cultured in B5 liquid medium was rapid, whereas shikonin production was high in MS liquid medium. Under B5 basal medium, sucrose concentration for optimal growth and shikonin production was 9% and 4% respectively. The growth and shikonin production on pH changes in B5 medium resulted little effect in pH 5.8 to pH 8.8 ranges, whereas growth was decreased dramatically in both above 8.8 and under 5.8. Nitrogen source and concentration effected on the growth and shikonin production. The highest growth rate was in B5 medium (50 mM $KNO_3$ and 1 mM $NaH_2PO_4)$, whereas the highest shikonin production was in the condition supplemented with 5 mM $KNO_3$ and 10 mM $NaH_2PO_4$.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.43 no.3 s.345
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• pp.15-20
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• 2006

A Newton-Raphson Method for table driven algorithm is presented in this paper. We concentrate the approximation of square root by using Newton-Raphson method. We confirm that this method has advantages of accurate and fast processing with optimized initial point. Hence the selection of the fitted initial points used in approximation of Newton-Raphson algorithm is important issue. This paper proposes that log scale based on geometric wean is most profitable initial point. It shows that the proposed method givemore accurate results with faster processing speed.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.31 no.3
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• pp.497-508
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• 2021

In this paper, we focus on optimizing the performance of CSURF, which uses the tweaked Montgomery curves. The projective version of elliptic curve arithmetic is slower on tweaked Montgomery curves than on Montgomery curves, so that CSURF is slower than the hybrid version of CSIDH. However, as the square-root Velu formula uses less number of ellitpic curve arithmetic than the standard Velu formula, there is room for optimization We optimize the square-root Velu formula and 2-isogeny formula on tweaked Montgomery curves. Our CSURFis 14% faster than the standard CSURF, and 10.8% slower than the CSIDH using the square-root Velu formula. The constant-time CSURF is 6.8% slower than constant-time CSIDH. Compared to the previous implementations, this is a remarkable result.

• CELLMED
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• v.11 no.3
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• pp.15.1-15.9
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• 2021

The chemical constitution of a drug has been accepted as an important basis for pharmacological action in Unani medicine. Various dosage forms have been developed on this concept, such as decoctions (Joshanda), infusions (Khesanda), extract (Rub / Usara), and syrup. Zarawand Mudaharaj (ZM.) / Aristolochia rotunda L. root was subjected to extraction process using Soxhlet's apparatus by using Response Surface Methodology (RSM) to design the number of random runs of the extracts with variation in the factors of temperature, the concentration of ethanol in water, time for extraction, for optimizing and maximizing the yield concentration. The data obtained, was analyzed with regression equation and ANOVA two-way summary to interpret the interaction of the factors for yield maximization. Minitab version 18 was used to design and analyze data. Validation of the optimum conditions for maximum yield of the whole extract of ZM. Root was carried out by re-run of the extract using the optimized conditions. The maximum yield percentage thus obtained using RSM was 20.87% whereas using these optimum conditions 21.35 % yield was obtained thereby validating the method. The association between the response functions and the process variables was identified by a three-factor recorded Box-Behnken design. In the present study RSM is used because itis a cheap and affordable method to optimize maximum yield percentage which may be reliably used by researchers. The study set in the surface conditions for ZM. root extraction by the Soxhlet apparatus for maximizing the yield percentage.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.29 no.9
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• pp.65-70
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• 2015

Minimal line length enables low-cost construction of the transmission lines and low-loss transportation of electric power. This paper presents a derivation to determine the coordinate and length of the straight line that minimally connects two perpendicular lines x-axis and y-axis via a specific point, using the optimization technique. The author shows a formula to obtain the minimal length, which is represented by the cube root of the coordinate given by the specific point. Case studies have been also discussed to prove the optimal solutions derived by the proposed formula.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.852-853
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• 2008

This paper proposes an optimal design method for the shape optimization of the permanent magnets (PM) of an in-wheel permanent magnet synchronous motor (PMSM) to reduce the cogging torque considering a total harmonic distortion (THD) and a root mean square (RMS) value of back-EMF. In this method, the Kriging model based on a design of experiment (DOE) is applied to interpolate the objective function in the spaces of design parameters. The optimal design method for the PM of an in-wheel PMSM has to consider multi-variable and multi-objective functions. The developed design method is applied to the optimization for the PM of an in-wheel PMSM.

• Journal of Ship and Ocean Technology
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• v.9 no.1
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• pp.64-71
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• 2005

In probabilistic design, the challenge is to estimate the uncertainty propagation, since outputs of subsystems at lower levels could constitute inputs of other systems or at higher levels of the multilevel systems. Three uncertainty propagation estimation techniques are compared in this paper in terms of numerical efficiency and accuracy: root sum square (linearization), distribution-based moment approximation, and Taguchi-based integration. When applied to reliability-based design optimization (RBDO) under uncertainty, it is investigated which type of applications each method is best suitable for. Two nonlinear analytical examples and one vehicle crashworthiness for side-impact simulation example are employed to investigate the unique features of the presented techniques for uncertainty propagation. This study aims at helping potential users to identify appropriate techniques for their applications in the multilevel design.

• Transactions on Electrical and Electronic Materials
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• v.13 no.3
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• pp.129-135
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• 2012

A number of surface mount technology (SMT) process variables including land design are considered for minimizing tombstone defect in flexible printed circuit assembly in high volume manufacturing. As SMT chip components have been reduced over the past years with their weights in milligrams, the torque that once helped self-centering of chips, gears to tombstone defects. In this paper, we have investigated the correlation of the assembly process variables with respect to the tombstone defect by employing statistically designed experiment. After the statistical analysis is performed, we have setup hypotheses for the root causes of tombstone defect and derived main effects and interactions of the process parameters affecting the hypothesis. Based on the designed experiments, statistical analysis was performed to investigate significant process variable for the purpose of process control in flexible printed circuit manufacturing area. Finally, we provide beneficial suggestions for find-pitch PCB design, screen printing process, chip-mounting process, and reflow process to minimize the tombstone defects.