• Asian-Australasian Journal of Animal Sciences
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• v.32 no.9
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• pp.1458-1468
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• 2019

Objective: As one of the most important metabolic organs, the liver plays vital roles in modulating the lipid metabolism. This study was to compare miRNA expression profiles of the Large White liver between two different developmental periods and to identify candidate miRNAs for lipid metabolism. Methods: Eight liver samples were collected from White Large of 70-day fetus (P70) and of 70-day piglets (D70) (with 4 biological repeats at each development period) to construct sRNA libraries. Then the eight prepared sRNA libraries were sequenced using Illumina next-generation sequencing technology on HiSeq 2500 platform. Results: As a result, we obtained 346 known and 187 novel miRNAs. Compared with the D70, 55 down- and 61 up-regulated miRNAs were shown to be significantly differentially expressed (DE). Gene ontology and Kyoto encyclopedia of genes and genomes enrichment analysis indicated that these DE miRNAs were mainly involved in growth, development and diverse metabolic processes. They were predicted to regulate lipid metabolism through adipocytokine signaling pathway, mitogen-activated protein kinase, AMP-activated protein kinase, cyclic adenosine monophosphate, phosphatidylinositol 3 kinase/protein kinase B, and Notch signaling pathway. The four most abundantly expressed miRNAs were miR-122, miR-26a and miR-30a-5p (miR-122 only in P70), which play important roles in lipid metabolism. Integration analysis (details of mRNAs sequencing data were shown in another unpublished paper) revealed that many target genes of the DE miRNAs (miR-181b, miR-145-5p, miR-199a-5p, and miR-98) might be critical regulators in lipid metabolic process, including acyl-CoA synthetase long chain family member 4, ATP-binding casette A4, and stearyl-CoA desaturase. Thus, these miRNAs were the promising candidates for lipid metabolism. Conclusion: Our study provides the main differences in the Large White at miRNA level between two different developmental stages. It supplies a valuable database for the further function and mechanism elucidation of miRNAs in porcine liver development and lipid metabolism.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.21 no.3
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• pp.29-43
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• 2010

The purposes of this study are to analyze the structure of the division and its operation related to bibliographic control in national libraries and to propose several ways to strengthen its functions of National Library of Korea based upon the analysis. Literature reviews were carried for the definitions and roles of national libraries and their bibliographic control. The divisions of bibliographic control in Library of Congress, British Library, National Diet Library of Japan, the Royal Library of Denmark, and National Library of Korea were analyzed. Three methods for strengthening bibliographic control in National Library of Korea were suggested as follows: first of all, need of establishment of independent bibliographic control center, secondly, high quality of bibliographic data and collaboration with related institutions, and third, strengthening of research in the future of bibliographic control.

• Journal of the Korean Society for Library and Information Science
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• v.53 no.4
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• pp.23-50
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• 2019

Libraries have recently sought to diversify their roles to meet the changing needs of local residents, while faithfully playing the library's original roles. The creation of a complex cultural space and the provision of services based on it are one of the ways to expand its role. In this study, a surveyed and analyzed the awareness of the complex cultural space of the library and the preference and awareness of the program operated in the complex cultural space by conducting a survey on the users of the library currently operating the complex cultural space. As a result, first, it was found that they preferred information space, education space, and rest space in space preference. On the other hand, community space and experience space showed low preference. Second, they prefer educational programs, exhibition programs, and performance programs that utilize complex cultural spaces, but experience programs and community programs have low preference. Therefore, it is necessary to operate the program by providing exhibitions and performance spaces while providing information and education spaces to users. The librarian should also promote the fact that library can be only the space of information and education, but also the space where culture, healing, experience and communication take place. In addition, libraries should strive to improve user awareness of library space.

• Korean Institute of Interior Design Journal
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• v.24 no.3
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• pp.146-155
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• 2015

It is an undeniable fact that the modern people's interest in knowledge and information and their roles are some of the core factors used to define the modern society. Besides, as phenomena indicating and leading the modern society, we have fusion, hybrid and convergence, etc. that combine several different elements into a new one. Such changes in social, cultural and technological circumstances require a paradigm shift for the composition of knowledge and information facilities and space. However, more diversified and advanced recently, interfaces for the delivery of knowledge and information cause users to show new behaviors and even change the spatial concept with space composition elements hybridized. Especially for the space of libraries, it is necessary to access and utilize any forms of knowledge and information data (digital + analog) regardless of time and space limitations and approach with an integrated spatial concept likely to change flexibly depending on social demands. In this light, this study aims to make a basic proposal for sustainable integrated-type hybrid space for the space of a public library in this era of knowledge and information. Particularly, this study intends to seek a way to establish a hybrid space model that can effectively converge the most important factors of the space of libraries (human-space(network)-information). With 18 different cases, this study analyzed knowledge and information composition systems, knowledge and information delivery systems and users' space systems. As a result, this study extracted 3 kinds of models, an information-based model, a culture-based model and an education-based model, with the integrated hybrid space model of knowledge and information facilities

• Journal of Information Management
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• v.26 no.2
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• pp.80-110
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• 1995

This study was carried out to analyze different types of information services to industries, provided by the Technical Information Department of government-supported research institutes. Today, demands on information of new technology have been rapidly increased with the expansion of information mind in enterprises. Managers, specially in profit organizations, are hunting for the technological information since they recognize that acquisition of information is directly connected with the success of business and technological innovation. However, it is not easy for them to get appropriate information due to such factors as competition, information blocking among profit organizations, shortage of holding library, etc. The roles of SciTech libraries can be divided into two parts; the first one is to promote information exchange among organizations, and the second one to supply users with proper information, processed and analyzed by the specialists. In this study, fifteen Technical Information Department of government-supported research institutes are surveyed to investigate their information services to industries. The results of survey show that their services are not enough to support industries successfully.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2008.11a
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• pp.859-862
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• 2008

As a research of NSO(Korea National Statistical Office), there are 609 public libraries in Korea. They have been increased 1.6 times for 10 years. Similar as libraries, their government officers are also increased 1.3 times. But number of users are increased 2.7times during the same period. Moreover, Because of deterioration of facilities, library can't satisfy user's needs, and it experienced difficulties to carry out its variety roles. In result, this study checked up maintenance conditions which are organization, facility, execution of budget and so on. Furthermore, it deduced problems like short of hands, lack of administrator's expertise and absence of accurate drawings, and suggests improvement.

• International Journal of Knowledge Content Development & Technology
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• v.1 no.1
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• pp.61-79
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• 2011

This study purposed to discover whether or not academic libraries reflect these changing roles. We selected K University as the research target and surveyed user satisfaction of materials, staff services, facilities, electronic devices, media, and so on. The research findings are as follows: 1) the frequency of library visits of University K was on the high side, 2) the primary purpose of using the academic library was associated with learning or reading, therefore, the most used library spaces were related to that, 3) the most used library materials were 'general books', the most unused were 'reference books', 4) the most preferred way to obtain needed materials when failing to find wanted materials was 'Contact librarian'. A similar phenomenon occurred in terms of facility use, 5) university K's users were usually satisfied with the loan policy, 6) the rate of users who don't know whether there is user education was very high, the rate of users who have no experience with user education was extremely low. These research findings can be referenced by library management to improve libraries' service quality and take advantage of complex spatial configurations.

• Journal of the Korean Society for Library and Information Science
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• v.58 no.1
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• pp.123-149
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• 2024

The purpose of this study is to present a plan to simplify the issuance of public library loan membership cards for children under the age of 14, and to devise measures to promote the convenience of using public libraries and to promote their use. To this end, related laws and systems, related services, and systems were analyzed. The issuance cases for each type were derived and analyzed by thoroughly investigating the procedure for issuing loan membership cards for children under the age of 14 in 1,211 public libraries nationwide, and focus group interviews were conducted. Based on this, the "double diamond model" was employed among service design methodologies to propose step-by-step guidelines for simplifying the procedure for issuing public library loan membership cards for children under the age of 14, as well as improving the environment, such as the roles of stakeholders, laws, and systems.

• Journal of the Korean Society for Library and Information Science
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• v.44 no.1
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• pp.199-215
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• 2010

This study aims to explore the key elements to facilitate public children's library services by investigating the current status and limitations in services. For this, data were collected through observations and in-depth interviews with library directors and children's librarians in public children's libraries in Seoul. The interviews were conducted based on the semi-structured interview technique. The content of the interview consisted of the vision and service status of the library, the competencies and roles of children's librarians, and ways to facilitate and improve children's services. The study discovered that libraries do not have a policy manual for operations and guidelines, and that their operations vary substantially according to the characteristics of the operating institutions. To resolve these problems, suggestions were made to facilitate children's library operations and services in order to enhance the professionalism of children's librarians.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.34 no.1
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• pp.5-26
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• 2023

This study was employed as a basic study to make a medium and long term development plan for a library system in Nowon-gu, Seoul. This study investigated the characteristics and local conditions of Nowon-gu, and analyzed public library system that can promote the development of the library by understanding the current state of the public library, the library's facility status, collections, manpower, and programs. Through the survey, the frequency and purpose of library use of local residents, users' opinions on satisfaction, collection development, expected roles, and policy directions were investigated. Depending on SWOT analysis, missions and strategies for midto long-term development plans for Nowon-gu Library were devised. Based on the research results, researchers proposed strengthening future education, reading culture, sustainable environmental library, and Nowon-gu cultural platform as development strategies.