• Title/Summary/Keyword: Roles Analysis

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The Roles of RUNX Family Proteins in Development of Immune Cells

  • Seo, Wooseok;Taniuchi, Ichiro
    • Molecules and Cells
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    • v.43 no.2
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    • pp.107-113
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    • 2020
  • The Runt-related transcription factors (RUNX) transcription factors have been known for their critical roles in numerous developmental processes and diseases such as autoimmune disorders and cancer. Especially, RUNX proteins are best known for their roles in hematopoiesis, particularly during the development of T cells. As scientists discover more types of new immune cells, the functional diversity of RUNX proteins also has been increased over time. Furthermore, recent research has revealed complicated transcriptional networks involving RUNX proteins by the current technical advances. Databases established by next generation sequencing data analysis has identified ever increasing numbers of potential targets for RUNX proteins and other transcription factors. Here, we summarize diverse functions of RUNX proteins mainly on lymphoid lineage cells by incorporating recent discoveries.

Analysis of Intermediary Roles and Technical Components for Smartglass-Assisted Interactive Remote Collaboration

  • Yoon, Hyoseok;Kim, Siyeon;Oh, Haneol;Lim, Hong Ji
    • Journal of Multimedia Information System
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    • v.8 no.4
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    • pp.295-300
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    • 2021
  • Recent advances in Internet-of-Things and wearable computing have established computationally sufficient infrastructure to remove the barriers of physical locations. The recent COVID-19 pandemic has accelerated the use of remote collaboration, work-from-home, teleconferencing, online education, digital twin, and metaverse enriched with various configurations of augmented reality, virtual reality, mixed reality, and extended reality. Beyond specialized niche wearable applications in the medical and entertainment domains, we aim to identify the underlying characteristics of smartglass-enabled killer applications for everyday use. In this paper, we analyze intermediary roles in remote collaboration consisting of authoritative supervisors, synergetic collaborators, and speculative explorers. We also propose technical components for smartglass-assisted interactive remote collaboration composed of personal tracking, teleconference, and interaction components. More specifically, the application tasks of each intermediary role and objectives of three functional components are defined and elaborated.

Experiences of Hospice and Palliative Nurses in Response to the COVID-19 Pandemic: A Qualitative Study

  • Kwon, Sinyoung;Choi, Sujin
    • Journal of Hospice and Palliative Care
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    • v.24 no.4
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    • pp.245-253
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    • 2021
  • Purpose: This study aimed to explore the experiences of hospice and palliative care (HPC) nurses at inpatient hospice centers in South Korea during the coronavirus disease 2019 pandemic. Methods: Data collection was conducted through individual interviews with 15 HPC nurses using face-to-face interviews, telephone calls, or Zoom videoconferencing. Data were analyzed using the thematic analysis method. Results: This study found that HPC nurses experienced practical and ethical dilemmas that reinforced the essential meaning and value of hospice and palliative care. The participants emphasized their practical roles related to compliance with infection prevention measures and their roles as rebuilders of hospice and palliative care. Conclusion: The findings of this study indicate that inpatient hospice centers must mitigate the practical and ethical dilemmas experienced by nurses, consider establishing explanation nursing units, and provide education to support nurses' highlighted roles during the pandemic. This study can be used to prepare inpatient hospice centers and the nurses that work there for future infectious disease outbreaks.

Roles of Malaysian Online Newspapers in the Construction of Public Opinion on Rare Earth Risks

  • Hasan, Nik Norma Nik;Dauda, Sharafa
    • Asian Journal for Public Opinion Research
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    • v.8 no.4
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    • pp.432-452
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    • 2020
  • This study explored the representation of risks from the controversial Lynas rare earth refining as a risk event by five Malaysian online mainstream and alternative newspapers using qualitative content analysis. The aim is to uncover the role of the news media in the social amplification and attenuation of risks within the literature evidence as those roles are still uncertain. Content analysis is used to explore the online newspapers' roles guided by the Social Amplification of Risk Framework (SARF). The representations typified environmental, financial, health, occupational, property, radioactive, and technological risks and established connections between four risk types (environmental, financial, radioactive, and health risks). Radioactive risk was repeatedly associated with other risks, suggesting that the volume and information flow focused on radioactive risk as a key ingredient for amplification. This connection shows that the nature of the relationship between risks is multidimensional, contradicting the unidirectional type found in previous studies. Alternative online newspapers amplified and attenuated more risks, thus, providing more diverse coverage than mainstream sources. Consequently, this study provides evidence that risk representation from rare earth refining in a digital news environment is multidimensional and intensified or weakened in a multi-layered pattern. The stakeholders are engaged in a contestation by positioning their narratives to oppose or support their interests, which are amplified or attenuated by the online newspapers as social amplification stations.

A Study on the Typologies of Family Values by Generation using Latent Profile Analysis (잠재프로파일 분석을 이용한 세대별 가족가치관의 유형 탐색 연구)

  • Shin, Youngmi
    • Human Ecology Research
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    • v.60 no.3
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    • pp.377-390
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    • 2022
  • This study identified and compared family values within and across different generations concerning gender roles, attitudes toward diverse families, children, and parental roles. Data were obtained from the 2020 Seoul Family Report Survey. There were 1,949 study subjects, including first- and second-generation baby boomers and individuals in generations X, Y, and Z in Korea. Latent profile analyses were conducted using M-plus. Perceptions and views concerning family values were classified into different types. The main findings were as follows. Two types were identified among first baby boomers, and three were identified among second baby boomers. Most of the first and second baby boomers belonged to the "moderate" type. Two types were detected among those in Generation X. Regarding gender roles, most views of Generation X were slightly progressive, while their other family values were more moderate. Three types were identified among those in Generation Y: "progressive," "moderate," and "very liberal." Generation Z was identified as a "progressive" group. This study provides basic data to explore the direction of the coexistence of generations by identifying and comparing diverse family values within and across generations.

Factors Influencing Innovation Capability and Operational Performance: A Case Study of Power Generation Fields in Vietnam

  • NGUYEN, To Tam;LE-ANH, Tuan;NGUYEN, Thi Xuan Hoa
    • The Journal of Asian Finance, Economics and Business
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    • v.9 no.5
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    • pp.541-552
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    • 2022
  • This research examines the effects of organizational learning and network involvement, as well as many contextual factors, on power generation businesses' innovation capability and operational success in Vietnam. This research also aims to attest to the moderating roles of top management support and company age, and firm possession type in the power generation industry. This study applied the exploratory factor analysis (EFA) and PLS-SEM approach for data analysis. In this research, we have tested hypotheses with data collected from 132 top managers and other key personnel from power generation companies in Vietnam. The results also attest to the moderating role of top management support on the two relationships between organizational learning - innovation capability and network involvement - innovation capability. Another important finding is that the company age has a negative impact on operational performance but shows a positive moderating role in the relationship between innovation capability and operational performance. This study highlights the central roles of organizational learning and innovation capability in impacting the organizational performance of power generation companies. These companies play a key role in supporting the development of industries in practice. This research also emphasizes the moderating roles of top management support and company age and possession type in practice.

Training Needs Analysis for the Roles and Competency of Field Representatives in Electric Work (전기공사 현장대리인의 역할 및 역량에 대한 교육요구분석)

  • Yun, Hyeon Woo;Yoon, Gwan Sik
    • 대한공업교육학회지
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    • v.40 no.1
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    • pp.142-162
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    • 2015
  • The purpose of this study are to provide the basic data materials and implementations for successful performance of electric-work field representatives of South Korean firms by identifying their roles and competency and examining their educational need. For this research purposes, three phased analysis was followed on: (1) the roles of electric-work field representatives, (2) competency of electric-work field representatives and (3) educational need for their competency. This research method was to conduct a focus group interview for 10 expert field representatives along with survey. The collected data materials were processed by MS Excel and SPSS 21.0 for statistical analysis including average, standard deviation and other basic statistics; the gap in awareness of field representatives; and need values. For the needs analysis, the difference between significance of field representatives' competency and current status was examined by t test. And the awareness gap between competency importance and current status was identified based on the Borich equation. The Locus for Focus model was employed herein to identify the kinds of competency with high importance and high inconsistency to prioritize. As a result, this research has found as follows: first, the roles of field representatives were found to be in 13 different kinds of roles. Second, electric-work field representatives were found to need to have 16 different skills. Third, regarding the 16 abilities, the gap between current status and significance was analyzed herein. The results showed statistically significant differences in all cases. The Borich needs analysis found the first required ability was communication ability followed by power of execution, conflict management ability, analytical thinking and time management ability. Also, the results of Locus for Focus model analysis displayed that the first quadrant(HH) included 7 highly-demanded abilities of communication ability, analytical thinking, decision making ability, specialty, time management ability, power of execution and drive for work implementation. The top-priority group was found to have 5 items of communication ability, analytical thinking, time management ability, power of execution and drive for work implementation which were commonly seen in the Locus for Focus model outcomes. Based on these findings, this research could identify the roles and competency of electric-work field representatives and provide the basic data materials applicable to future personal management of electricity companies including recruitment, division of work, job description, evaluation, etc. Also this research offered guidelines on demanded abilities in the field and where to place priority. The kinds of abilities with high educational demand as found in this research must be considered in designing educational programs for the competency building of field representatives. This research is expected to provide useful information in developing such educational programs for field representatives.

Roles of Health-Oriented Personal Factors in Influencing Koreans' Perceptions about Telemedicine: Exploration of Regional Differences

  • Jaehee Cho;Ghee-Young Noh
    • Asia pacific journal of information systems
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    • v.27 no.3
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    • pp.176-190
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    • 2017
  • This study aimed to investigate the roles of three health-oriented personal factors-health technology innovativeness (HTI), health consciousness (HC), and health information orientation (HIO)-in determining Koreans' perceptions about telemedicine. Based on an extended version of the technology acceptance model (TAM), two perceptual components-perceived usefulness (PU) and perceived ease of use (PEOU)-of telemedicine were considered for this investigation. Data from 699 usable surveys were analyzed using path analysis. The results from the path analysis indicated that while HTI and HC had no or limited effects on the PU and PEOU of telemedicine, the effects of HIO on those two perceptual components of telemedicine were statistically significant. Moreover, the results from the path analysis showed that there were significant regional differences in the effects of HTI and HC on the PU and PEOU of telemedicine. In general, these effects were greater among the metropolitan residents than they were among the rural residents.

An Analysis of Multimedia Materials in E-works (E-book) of Elementary Science Textbook (초등과학교과서 전자저작물에 탑재된 멀티미디어 자료 분석)

  • Ha, Ji-hoon;Shin, Youngjoon
    • Journal of Korean Elementary Science Education
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    • v.35 no.1
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    • pp.65-77
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    • 2016
  • The purpose of this paper was to analyze the kinds and roles of multimedia materials in E-works that are distributed with elementary textbooks (3~6 grade) of the 2009 revised science curriculum. Five criteria (forms, goals, key competencies, inquiry process, running time) were set for this. The sample of the paper was the 784 multimedia materials in E-works of elementary science textbooks (3~6 grade) of the 2009 revised science curriculum. The results of the multimedia materials analysis are as follows: The result of the material forms of multimedia is that the form of highest ratio is text type. But all forms were used evenly in E-work. 56.2% of the multimedia materials are for "inquiry" in the goal criteria, and 65.0% of the multimedia materials are related to "science inquiry" in the key competencies criteria. Two facts indicate many multimedia is used to develop students' inquiry ability. However the ratio of multimedia materials in motivation step is higher than that in inquiry activity step. In analysis of running time, the ratio of "under 5 min" multimedia materials is the highest. But, the ratio of 5~10 min multimedia materials in inquiry part is higher than that in motivation part in The Chi-square test between "running time" and "parts" that consist of motivation part and inquiry part. Through the analysis of module and the categorizing the multimedia materials, we found that the multimedia materials play eleven roles in E-works that are distributed with elementary textbooks.

In silico genome wide identification and expression analysis of the WUSCHEL-related homeobox gene family in Medicago sativa

  • Yang, Tianhui;Gao, Ting;Wang, Chuang;Wang, Xiaochun;Chen, Caijin;Tian, Mei;Yang, Weidi
    • Genomics & Informatics
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    • v.20 no.2
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    • pp.19.1-19.15
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    • 2022
  • Alfalfa (Medicago sativa) is an important food and feed crop which rich in mineral sources. The WUSCHEL-related homeobox (WOX) gene family plays important roles in plant development and identification of putative gene families, their structure, and potential functions is a primary step for not only understanding the genetic mechanisms behind various biological process but also for genetic improvement. A variety of computational tools, including MAFFT, HMMER, hidden Markov models, Pfam, SMART, MEGA, ProtTest, BLASTn, and BRAD, among others, were used. We identified 34 MsWOX genes based on a systematic analysis of the alfalfa plant genome spread in eight chromosomes. This is an expansion of the gene family which we attribute to observed chromosomal duplications. Sequence alignment analysis revealed 61 conserved proteins containing a homeodomain. Phylogenetic study sung reveal five evolutionary clades with 15 motif distributions. Gene structure analysis reveals various exon, intron, and untranslated structures which are consistent in genes from similar clades. Functional analysis prediction of promoter regions reveals various transcription binding sites containing key growth, development, and stress-responsive transcription factor families such as MYB, ERF, AP2, and NAC which are spread across the genes. Most of the genes are predicted to be in the nucleus. Also, there are duplication events in some genes which explain the expansion of the family. The present research provides a clue on the potential roles of MsWOX family genes that will be useful for further understanding their functional roles in alfalfa plants.