• Clinical and Experimental Pediatrics
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• v.64 no.8
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• pp.393-399
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• 2021

Food allergies and food-induced anaphylaxis are important health problems. Several cofactors modulating the onset of anaphylaxis have been identified. In the presence of cofactors, allergic reactions may be induced at lower doses of food allergens and/or become severe. Exercise and concomitant infections are well-documented cofactors of anaphylaxis in children. Other factors such as consumption of nonsteroidal anti-inflammatory drugs, alcohol ingestion, and stress have been reported. Cofactors reportedly play a role in approximately 30% of anaphylactic reactions in adults and 14%-18.3% in children. Food-dependent exercise-induced anaphylaxis (FDEIA) is the best-studied model of cofactor-induced anaphylaxis. Wheat-dependent exercise-induced anaphylaxis, the most common FDEIA condition, has been studied the most. The mechanisms of action of cofactors have not yet been fully identified. This review aims to educate clinicians on recent developments in the role of cofactors and highlight the importance of recognizing cofactors in food allergies and food-induced anaphylaxis.

• International Journal of Naval Architecture and Ocean Engineering
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• v.4 no.1
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• pp.57-70
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• 2012

This article presents a numerical investigation concerning the effect of two kinds of axially progressing internal flows (namely, upward and downward) on fluid.structure interaction (FSI) dynamics about a marine riser model which is subject to external shear current. The CAE technology behind the current research is a proposed FSI solution, which combines structural analysis software with CFD technology together. Efficiency validation for the CFD software was carried out first. It has been proved that the result from numerical simulations agrees well with the observation from relating model test cases in which the fluidity of internal flow is ignorable. After verifying the numerical code accuracy, simulations are conducted to study the vibration response that attributes to the internal progressive flow. It is found that the existence of internal flow does play an important role in determining the vibration mode (/dominant frequency) and the magnitude of instantaneous vibration amplitude. Since asymmetric curvature along the riser span emerges in the case of external shear current, the centrifugal and Coriolis accelerations owing to up- and downward internal progressive flows play different roles in determining the fluid.structure interaction response. The discrepancy between them becomes distinct, when the velocity ratio of internal flow against external shear current is relatively high.

• Genomics & Informatics
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• v.20 no.4
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• pp.40.1-40.8
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• 2022

The concepts of phylogeny and floral genetics play a crucial role in understanding the origin and diversification of flowers in angiosperms. Angiosperms evolved a great diversity of ways to display their flowers for reproductive success with variations in floral color, size, shape, scent, arrangements, and flowering time. The various innovations in floral forms and the aggregation of flowers into different kinds of inflorescences have driven new ecological adaptations, speciation, and angiosperm diversification. Evolutionary developmental biology seeks to uncover the developmental and genetic basis underlying morphological diversification. Advances in the developmental genetics of floral display have provided a foundation for insights into the genetic basis of floral and inflorescence evolution. A number of regulatory genes controlling floral and inflorescence development have been identified in model plants such as Arabidopsis thaliana and Antirrhinum majus using forward genetics, and conserved functions of many of these genes across diverse non-model species have been revealed by reverse genetics. Transcription factors are vital elements in systems that play crucial roles in linked gene expression in the evolution and development of flowers. Therefore, we review the sex-linked genes, mostly transcription factors, associated with the complex and dynamic event of floral development and briefly discuss the sex-linked genes that have been characterized through next-generation sequencing.

• Asia pacific journal of information systems
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• v.23 no.1
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• pp.107-132
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• 2013

Despite the importance of knowledge complementarities (KC) to firm performance, very little is known about exactly what constitutes KC and how synergistic knowledge is created in KC. This research looks into the dimensionality of KC and how synergistic knowledge as an essential component of KC is generated in a process innovation (PI) project. We propose that KC consists of potential complementary knowledge, collaborative elaboration (CE) process, and synergistic knowledge. The model is investigated quantitatively, using a sample of 26 matched-pairs of client and consultant who participated in a PI project, and then qualitatively using interviews of a sub-sample of 7 matched-pairs of client and consultant. Data were collected in a longitudinal way at four different points during the four month project period. Results show that consultant's learning about the client's business occurs first and then client learning about IT capabilities follows through CE. With this enhanced clients' knowledge about IT capabilities, clients play an initiative role in designing the To-Be business processes, while consultants play a supporting role by introducing best practices or making suggestions based on their experiences. Future research implications as well as practical implications are also discussed.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.12
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• pp.1175-1184
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• 2020

This research examines the personal (i.e., Machiavellianism) and situational factors (i.e., tax climate) that are believed to be psychologically salient aspects in tax compliance. To the best of our knowledge, no research has been carried out to investigate the interaction effect of the two factors. This study uses a paper-and-pencil laboratory experiment 2x2 between-subject factorial design that involved 158 participants. The results indicate that a taxpayer who has a low Machiavellianism score or who is in a high synergistic tax climate reports a higher level of income. In the high synergistic tax climate, where tax norms apply, personal ethics do not play a significant role in tax compliance decisions. Where the synergistic relationship between taxpayer and authorities is low, personal ethics play an important role, i.e., low Machiavellians report a higher reported income than high Machiavellians do. This research contributes to the literature that deviates from the traditional model of tax compliance. Taxpayers are not always rational, but they might pay tax for reasons other than financial motives (Alm, 1991, 2018), that is, personal ethics in this study. This research implies the need for policymakers to consider other approaches rather than only relying on audits and fines.

• 한국정보교육학회:학술대회논문집
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• 2010.08a
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• pp.67-73
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• 2010

In information and communications society, the numbers of elementary students who violate copyright law have been growing due to lack of understanding so they are needed to be educated on copyright. However, current education only has focused on copyright infringement, few numbers of educations have instructed copyright oriented examples linked to regular curriculum. Therefore, the purpose of this study is to grow elementary students's understanding of copyright and find new ways of education through designed copyright education program oriented regular curriculum.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.1
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• pp.229-238
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• 2020

A model is presented in this paper to provide understanding of the supply chain integration and supply chain information practices' impact on the manufacturing industries. The supply chain information practices play a crucial role in sharing information between the members of SC network. Thus, it is important to develop a comprehensive understanding of the differences and similarities among ISI and information management. It will allow firms to systematically evaluate and carefully choose the information strategy. The empirical findings of this research offer essential and interesting insights about what role SCI, supply chain information and Supply chain ISI play in determining Malaysia's financial performance. The theoretical gaps addressed in this study are of significant importance, since a little empirical evidence is available regarding system infrastructure and supply chain information management's effectiveness. This research provides further paths of exploring system infrastructure and information management, thereby defining the manufacturing industries' next step in SCM struggle i.e. modifying total integrated SC principle in other manufacturing firms. The Resource-based theory discovered organizational resources as an essential organizational success ingredient. Therefore, in order to recognize its potential value, internal resources, for instance, information system and management must be fully utilized.

• Human Ecology Research
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• v.58 no.3
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• pp.299-313
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• 2020

This study investigated the relationship among fathers' parenting involvement, mothers' parenting competence, and young children's self-control. Participants consisted of 325 mothers and young children (169 boys and 153 girls) from the Seoul area who completed questionnaires on fathers' parenting involvement, mothers' parenting competence, and young children's self-control. Data were statistically analyzed using basic descriptive statistics, Pearson's correlation, and multiple regression analysis. Baron and Kenny's method was examined. Subsequently, the Sobel test was performed to check the mediating model's significance and was adapted to SPSS version 21.0 for Windows. The major findings were as follows. First, fathers' parenting involvement was positively correlated with young children's self-control and mothers' parenting competence. Second, mothers' parenting competence was positively correlated with young children's self-control. The mothers' parenting competence indicated a tendency to play a perfectly/partially play a mediating role between fathers' parenting involvement and young children's self-control; consequently, a fathers' parenting involvement had a direct effect as well as an indirect effect through the mothers' parenting competence on young children's self-control. The results indicated that a mothers' parenting competence plays a crucial role in the relationship between a fathers' parenting involvement and the young children's self-control.

• BMB Reports
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• v.41 no.2
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• pp.102-107
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• 2008

Extracellular proteases play an important role in a wide range of host physiological events, such as food digestion, extracellular matrix degradation, coagulation and immunity. Among the large extracellular protease family, serine proteases that contain a "paper clip"-like domain and are therefore referred to as CLIP-domain serine protease (clip-SP), have been found to be involved in unique biological processes, such as immunity and development. Despite the increasing amount of biochemical information available regarding the structure and function of clip-SPs, their in vivo physiological significance is not well known due to a lack of genetic studies. Recently, Drosophila has been shown to be a powerful genetic model system for the dissection of biological functions of the clip-SPs at the organism level. Here, the current knowledge regarding Drosophila clip-SPs has been summarized and future research directions to evaluate the role that clip-SPs play in Drosophila immunity are discussed.

• Journal of Distribution Science
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• v.17 no.9
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• pp.15-23
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• 2019

Purpose - This study was aimed to investigate the moderating effects of cobranding promotions that are rare in brand experience and brand loyalty studies, and to find out cobranding promotions can play a moderating role to enhance positive effects on the relationship between brand experience and brand loyalty, and to figure out the cobranding types which can lead to positive brand loyalty. Research design, data, and methodology - The conceptual research model was developed to explain the effects, and 2018 Interbrand's global top 15 brands such as Apple, Google, Amazon, Samsung were suggested to be selected from 377 Amazon Mechanical Turk respondents to answer the 22 survey questions made by Qualtrics with 5-point Likert scale. Results - In this research, the moderating effects of cobranding have been confirmed on the relationships between brand experience and loyalty, and the positive cobranding promotions can have significant effects on the relationships, but only for the least experienced brand was significant. Regarding to cobranding types, there were no significant ones to enhance brand loyalty. Conclusions - The findings confirmed that cobranding promotion experience can play a positive moderating role to brand loyalty, and the loyalty can be maximized if companies can provide positive cobranding experiences to their own consumers.