• Journal of Periodontal and Implant Science
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• v.25 no.2
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• pp.438-457
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• 1995

The origin of fibroblasts, their proliferative activity and roles in the early stages of periodontal regeneration were investigated in order to better understand the periodontal healing process in furcation defects of the beagle dog after guided tissue regeneration. Newly divided cells were identified and quantitated by immunolocalization of bromodeoxyuridine (BrdU) injected 1 hour prior to sacrificing the animals. The results were as follows :1. During periodontal healing in horizontal furcation defect, three different stages, namely the granulation tissue, connective tissue, and bone formation stages, were identified on the basis of major types of cells and tissue. 2. In the early stages of periodontal regeneration, both the remaining periodontal ligament and alveolar bone compartment were the major sources. 3. The majority of BrdU-labeled fibroblasts were located at the following areas ; 1) the coronal zone of the defect in case of the connective tissue fanned on the root surface. 2) the area within an 400 ${\mu}m$ distance from the remaining bone level in case of the periodontal ligament. 3) the area within an 100 ${\mu}m$ distance from the bone surface in case of areas of active bone formation.4. The highly proliferative fibroblasts adjacent to bone surface played a major role in the formation of osteoblast precursor cells, whereas both paravascular and endosteal cells played a minor role in new bone formation, In conclusion, it was suggested that the fibroblasts in the remaining periodontal ligament and bone will play a major role in periodontal regeneration, whereas both paravascular and endosteal cells will play a minor role in new bone formation.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.8
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• pp.1065-1074
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• 2016

Growth factors play an important role during early ovarian development and folliculogenesis, since they regulate the migration of germ cells to the gonadal ridge. They also act on follicle recruitment, proliferation/atresia of granulosa cells and theca, steroidogenesis, oocyte maturation, ovulation and luteinization. Among the growth factors, the growth differentiation factor 9 (GDF9) and the bone morphogenetic protein 15 (BMP15), belong to the transforming growth factor beta (TGF-${\beta}$) superfamily, have been implicated as essential for follicular development. The GDF9 and BMP15 participate in the evolution of the primordial follicle to primary follicle and play an important role in the later stages of follicular development and maturation, increasing the steroidogenic acute regulatory protein expression, plasminogen activator and luteinizing hormone receptor (LHR). These factors are also involved in the interconnections between the oocyte and surrounding cumulus cells, where they regulate absorption of amino acids, glycolysis and biosynthesis of cholesterol cumulus cells. Even though the mode of action has not been fully established, in vitro observations indicate that the factors GDF9 and BMP15 stimulate the growth of ovarian follicles and proliferation of cumulus cells through the induction of mitosis in cells and granulosa and theca expression of genes linked to follicular maturation. Thus, seeking greater understanding of the action of these growth factors on the development of oocytes, the role of GDF9 and BMP15 in ovarian function is summarized in this brief review.

• The Journal of the Korea Contents Association
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• v.15 no.2
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• pp.419-432
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• 2015

This study analyzed the moderating role of the suitability factors of corporate strategies and information system strategies targeting small and medium sized transportation companies in Korea. The analytical result has found that the suitable factors of corporate strategies and information system strategies play the moderating role in the ERP introduction factors and internal performance. In other words, the suitability factors of corporate strategies and information system strategies were analyzed to play the moderating role in support of CEOs, education/training, users' IT capabilities, standardization/formulation of business, infrastructure of information technologies, and internal performance. The result of this study based on the above analytical results has found that introduction performance will be maximized when ERP packages are introduced in the small and medium-sized transportation companies and corporate strategies properly harmonize with the introduction strategies of ERP packages in the companies.

• IMMUNE NETWORK
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• v.14 no.3
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• pp.128-137
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• 2014

Respiratory viruses can induce acute respiratory disease. Clinical symptoms and manifestations are dependent on interactions between the virus and host immune system. Dendritic cells (DCs), along with alveolar macrophages, constitute the first line of sentinel cells in the innate immune response against respiratory viral infection. DCs play an essential role in regulating the immune response by bridging innate and adaptive immunity. In the steady state, lung DCs can be subdivided into $CD103^+$ conventional DCs (cDCs), $CD11b^+$ cDCs, and plasmacytoid DCs (pDCs). In the inflammatory state, like a respiratory viral infection, monocyte-derived DCs (moDCs) are recruited to the lung. In inflammatory lung, discrimination between moDCs and $CD11b^+$ DCs in the inflamed lung has been a critical challenge in understanding their role in the antiviral response. In particular, $CD103^+$ cDCs migrate from the intraepithelial base to the draining mediastinal lymph nodes to primarily induce the $CD8^+$ T cell response against the invading virus. Lymphoid $CD8{\alpha}^+$ cDCs, which have a developmental relationship with $CD103^+$ cDCs, also play an important role in viral antigen presentation. Moreover, pDCs have been reported to promote an antiviral response by inducing type I interferon production rather than adaptive immunity. However, the role of these cells in respiratory infections remains unclear. These different DC subsets have functional specialization against respiratory viral infection. Under certain viral infection, contextually controlling the balance of these specialized DC subsets is important for an effective immune response and maintenance of homeostasis.

• Journal of Fashion Business
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• v.9 no.6
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• pp.141-159
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• 2005

Targeting a film that is the medium of having powerful influence upon the masses, the present study examined about a role and characteristics in the movie costume, and a role of costume designers, which are shown in process of being changed the film costume. There are many designers who were in charge of the film costume, but the present study examined centering on designers who participated aiming to create the image of a character from the stage of manufacturing a movie. It presented and analyzed visual materials by dividing four genres such as a historical drama movie, a horror movie, a fantasy movie, and a modern-play movie, and by selecting a typical work. A Historical drama movie needs to be investigated costume by the historical background in a movie, but inside it was shown clothes that were elaborately reproduced and newly created. A horror movie plays a role of medium that reflects the human society and the internal mentality of a human being along with the attribute of entertainment. As a genre that requires much costume, make-up and special effect aiming at dramatic effect, a role of film costume possesses great weight. As a fantasy movie is a field based on 'fiction' of a writer who creates a work, it is a field that requires creativity of a costume designer most. As a modern-play movie is what reproduces reality, it best reflects the phases of that time, and is the field that is influenced by costume or fashion trend. Costume needs to be designed in a bid to allow spectators to be inspired the wholly united and harmonious mood with leading a story of a movie, and the individual image.

• Proceedings of the Materials Research Society of Korea Conference
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• 1994.11a
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• pp.156-162
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• 1994

The existence of the elastic anisotropic channeling is based on the experimental evidences. The rotating electron pairs orbits play the role of basic bonding orbitals. The abnormal signals from ligand domain and train-membrane in cancer cell, Deformation in fatigue and creep at low stress, con duction, superconduction and semiconduction are all from the new metallic bonding orbital.

• Journal of the Chungcheong Mathematical Society
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• v.8 no.1
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• pp.137-145
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• 1995

In the white noise analysis the one-parameter groups play the powerful role. In this report, we will see a subgroup of infinite dimensional unitary group $U_{\infty}$ including guage transform and structure of this subgroup under the view point of Lie algebra.

• Honam Mathematical Journal
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• v.34 no.3
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• pp.451-465
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• 2012

Since there are several kinds of continuities of maps between digital spaces, the paper compares them, which can play an important role in digital topology and discrete geometry.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.757-761
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• 2004

Flat Panel Display (FPD) application of Television (TV) application is booming. Liquid Crystal Display (LCD) is forecasted to play a dominant role for TV application in next years. We review in this presentation LC material development for LCD TV application.

• Journal for History of Mathematics
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• v.22 no.1
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• pp.75-88
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• 2009

In this article it is investigated what role analysis play in the reasoning. The author suggests that the mathematical statements should be reformulated so that analysis can be activated in the reasoning.