• Title/Summary/Keyword: Role Models

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An Exploratory Study on the Risks and Threats of SNS(Social Network Service): From a Policing Perspective (SNS(Social Network Service)의 위험성 및 Policing(경찰활동)에 미칠 영향에 대한 시론적 연구)

  • Choi, Jin-Hyuk
    • Korean Security Journal
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    • no.29
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    • pp.301-336
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    • 2011
  • This exploratory study aims to review the risks and threats of social network services(SNSs), particularly focusing upon the policing perspective. This paper seeks to acknowledge the present risk/danger of SNSs and the very significance of establishing a strategic framework to effectively prevent and/or control criminal misuse of SNSs. This research thus advocates that proactive study on security issues and criminal aspects of SNSs and preventive countermeasures can play a significant role in policing the networked society in the time of digital/internet age. Social network sites have been increasingly attracting the attention of entrepreneurs, and academic researchers as well. In this exploratory article, the researcher tried to define concepts and features of SNSs and describe a variety of issues and threats posed by SNSs. After summarizing existing security risks, the researcher also investigated both the potential threats to privacy associated with SNSs, such as ID theft and fraud, and the very danger of SNSs in case of being utilized by terrorists and/or criminals, including cyber-criminals. In this study, the researcher primarily used literature reviews and empirical methods. The researcher thus conducted extensive case studies and literature reviews on SNSs. The literature reviews herein cover theoretical discussions on characteristics, usefulness, and/or potential danger/harm of SNSs. Through the literature review, the researcher also concentrated upon being able to identify a strategic framework for law enforcement to effectively prevent criminal misuse of SNSs The limitation of this study can be lack of statistical data and attempts to examine previously un-researched area in the field of SNS and its security risks and potential criminal misuse. Thus, to supplement this exploratory study, more objective theoretical models and/or statistical approaches would be needed to provide law enforcement with sustainable policing framework and contribute to suggesting policy implications.

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Herbal Acupuncture of Nidus Vespae Suppresses c-Fos Expression by TNBS Induced Colitis in Rats (TNBS로 유도된 흰쥐의 대장염(大腸炎)에 대한 노봉방(露蜂房) 약침(藥鍼)의 효과)

  • Song, Jeong-Bang;Kim, Jae-Hyo;Kim, Yu-Lee;Park, Yu-Ree;Ahn, Seong-Hun;Sohn, In-Chul
    • Korean Journal of Acupuncture
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    • v.26 no.4
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    • pp.195-209
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    • 2009
  • Objectives : Transient inflammation has been demonstrated to alter visceral sensory function in animal models and acute mucosal inflammation may precede the manifestation of visceral hyperalgesia. Thus in this study we compared effects of herbal acupuncture of Nidus Vespae (NV) applied to the different acupoints in the acute colitis induced by trinitrobenzenesulphonic acid (TNBS) intracolonic injection in rats. Methods : In Male Sprague-Dawley rats, weighing 250 ~ 400 g, TNBS (5 mg/kg) was infused intrarectally through a silicon rubber catheter into the anus under isoflurane anaesthesia. Under general anesthesia, acupoints of LI4 (Hapkok), SI25 (Cheonchu), ST36 (Joksamni), BL25 (Daejangsu) were intramuscularly injected by NV. Expressions of cFos protein in the periaqueductal gray (PAG), locus coeruleus (LC), nucleus of solitary tract (Sol), and the 6th lumbar spinal cord (L6 s.c.) were observed at 24 hrs after TNBS induced colitis by immunohistochemistry. Results : The expression of c-Fos protein in L6 s.c., Sol, LC and PAG increased 24 hrs after TNBS injection into colorectum as compared to normal group. NV herbal acupuncture also inhibited the expression of c-Fos protein in Sol but not L6 s.c., LC, and PAG. NV to ST36 inhibited significantly the c-Fos expression in Sol and PAG. NV to ST25 inhibited the c-Fos protein expression all over the observation area. NV to BL25 showed the inhibitory effects in the areas except LC. Whether or not a role of endogenous opioids, intrathecal injection of naltrexone (30 ug / 30 ul) was applied before the 2nd herbal acupuncture treatment 24 hrs after TNBS-induced colitis in rat. Naltrexone reversed the inhibition of c-Fos protein expression in the spinal cord and brainstem under different conditions such as type of herbal acupuncture compound and choice of acupoint. Conclusions : In summary, these data show that herbal acupuncture of NV inhibits signal pathways such as spinal cord and brain stem ascending hypersensitivity of colorectum after TNBS induced colitis. This effect may be mediated by acupoints through the endogenous opioid system involving the pain modulation.

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A Conserved Mechanism for Binding of p53 DNA-Binding Domain and Anti-Apoptotic Bcl-2 Family Proteins

  • Lee, Dong-Hwa;Ha, Ji-Hyang;Kim, Yul;Jang, Mi;Park, Sung Jean;Yoon, Ho Sup;Kim, Eun-Hee;Bae, Kwang-Hee;Park, Byoung Chul;Park, Sung Goo;Yi, Gwan-Su;Chi, Seung-Wook
    • Molecules and Cells
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    • v.37 no.3
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    • pp.264-269
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    • 2014
  • The molecular interaction between tumor suppressor p53 and the anti-apoptotic Bcl-2 family proteins plays an essential role in the transcription-independent apoptotic pathway of p53. In this study, we investigated the binding of p53 DNA-binding domain (p53DBD) with the anti-apoptotic Bcl-2 family proteins, Bcl-w, Mcl-1, and Bcl-2, using GST pull-down assay and NMR spectroscopy. The GST pull-down assays and NMR experiments demonstrated the direct binding of the p53DBD with Bcl-w, Mcl-1, and Bcl-2. Further, NMR chemical shift perturbation data showed that Bcl-w and Mcl-1 bind to the positively charged DNA-binding surface of p53DBD. Noticeably, the refined structural models of the complexes between p53DBD and Bcl-w, Mcl-1, and Bcl-2 showed that the binding mode of p53DBD is highly conserved among the anti-apoptotic Bcl-2 family proteins. Furthermore, the chemical shift perturbations on Bcl-w, Mcl-1, and Bcl-2 induced by p53DBD binding occurred not only at the p53DBD-binding acidic region but also at the BH3 peptide-binding pocket, which suggests an allosteric conformational change similar to that observed in Bcl-$X_L$. Taken altogether, our results revealed a structural basis for a conserved binding mechanism between p53DBD and the anti-apoptotic Bcl-2 family proteins, which shed light on to the molecular understanding of the transcription-independent apoptosis pathway of p53.

Implications and numerical application of the asymptotical shock wave model (점진적 충격파모형의 함축적 의미와 검산)

  • Cho, Seong-Kil
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.11 no.4
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    • pp.51-62
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    • 2012
  • According to the Lighthill and Whitham's shock wave model, a shock wave exists even in a homogeneous speed condition. They referred this wave as unobservable- analogous to a radio wave that cannot be seen. Recent research has attempted to identify how such a counterintuitive conclusion results from the Lighthill and Whitham's shock wave model, and derive a new asymptotical shock wave model. The asymptotical model showed that the shock wave in a homogenous speed traffic stream is identical to the ambient vehicle speed. Thus, no radio wave-like shock wave exists. However, performance tests of the asymptotical model using numerical values have not yet been performed. We investigated the new asymptotical model by examining the implications of the new model, and tested it using numerical values based on a test scenario. Our investigation showed that the only difference between both models is in the third term of the equations, and that this difference has a crucial role in the model output. Incorporation of model parameter${\alpha}$ is another distinctive feature of the asymptotical model. This parameter makes the asymptotical model more flexible. In addition, due to various choices of ${\alpha}$ values, model calibration to accommodate various traffic flow situations is achievable. In Lighthill and Whitham's model, this is not possible. Our numerical test results showed that the new model yields significantly different outputs: the predicted shock wave speeds of the asymptotical model tend to lean toward the downstream direction in most cases compared to the shock wave speeds of Lighthill and Whitham's model for the same test environment. Statistical tests of significance also indicate that the outputs of the new model are significantly different than the corresponding outputs of Lighthill and Whitham's model.

VOT Derivation for Different Trip Purposes, Travel Modes and Testing of Their Significance (통행목적별 수단별 통행시간가치도출 및 유의성 검정)

  • Kim, Hyeon;Oh, Se-Chang;Choi, Gi-Ju
    • Journal of Korean Society of Transportation
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    • v.17 no.1
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    • pp.113-129
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    • 1999
  • It is widely recognized that the value of travel time (VOT) plays an important role both in choosing the transportation alternatives on an individual level, and in analyzing and evaluating transportation plans and other public policy makings on a collective level. There is, however, a great deal of difficulties to correctly estimate the VOT. In addition, although there are lots of methods to estimate the VOT so for, not many recommendations have been presented to reflect the localities associated with the VOT derivation in Korea. This study aims at deriving the VOT for different trip purposes and travel modes with their significances tested. To accomplish this purposes, a logit-based travel mode choice model based on revealed preference (RP) data has been formulated, calibrated using the discrete choice model of LIMDEP package for various trip purpose models. For each trip purpose and travel mode, the VOT has been calculated along with the significance testing of the derived VOTs. From the results given in this research, the VOTs for different purposes and modes are identified different, and they are statistically significant. The updated results here in this paper may be a yardstick in evaluating the transportation plans and policies by providing more detailed VOT information for different categories, especially in urban context.

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A Meta-Analysis on the Effect of Batterer Intervention Programs (부부폭력 가해자프로그램의 효과에 대한 메타분석)

  • Chang, Hee suk;Heo, In Yeong
    • Korean Journal of Social Welfare Studies
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    • v.49 no.4
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    • pp.101-129
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    • 2018
  • This study examined the overall effect size of the batterer intervention programs aimed at reducing violent behavior. This study calculated the 18 results and the 115 effect sizes of 11 theses published from 2000 to 2017 in Korea. It was demonstrated that the effect of an offender's program on the change in violent behavior was significant at both the practical and treatment level. The effect size was high in the order of control behavior, emotional violence, and physical violence. The effects of dependent variables other than violence were also researched. The batterer program positively changed the participant's attitudes in terms of sex-role and partner violence. Furthermore, it decreased the level of anger and depression, and enhanced self-esteem and communication skills thus increasing satisfaction in marital relationships. In addition, this study examined the factors that influence the effect of the offender's program in terms of the decrease of violent behavior. Upon analysis, it was examined that the moderating effect was great in the approach model and counsel form. More specifically, it was revealed that the feminist-cognitive behavioral models had a greater effect than the compromise model or single model. In terms of counsel forms, group counseling formed only of male offenders had greater effect than couples treatment group. Based on these findings, this study discussed the practical means for increasing the effect of batterer intervention programs.

A Role for Ginseng in the Control of Postprandial Glycemia and Type 2 Diabetes

  • Vuksan Vladimir;Sievenpiper John L;Xu Zheng;Zdravkovic Uljana Beljan;Jenkins Alexandra L;Arnason John T;Bateman Ryon M.;Leiter Lawrence A;Josse Robert G;Francis Thomas;Stavro Mark P
    • Proceedings of the Ginseng society Conference
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    • 2002.10a
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    • pp.1-19
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    • 2002
  • The use of herbals has increased considerably while their efficacy and safety remain untested. This unsupported surge in demand has prompted a call for their clinical evaluation. One area in which evaluations are emerging is ginseng and diabetes. Growing evidence is accumulating from in vitro and animal models indicating that various ginseng species, American (Panax quinquefolius L), Asian (Panax ginseng C.A. Meyer), Korean Red, San-chi (Panax notoginseng [Burk.] P.R. Chen), and the non-panax species Siberian (Eleutherococcus senticossus) ginsing, and their fractions, saponins (ginsenosides) and peptidoglycans (panaxans for panax species and eleutehrans for Siberian ginseng), might affect carbohydrate metabolism and related signaling molecules. Recent human studies from our laboratory have also shown a blood glucose lowering effect of American ginseng (AG) and some other ginseng spices postprandially after acute administration and chronically after administration for 8-weeks in people with type 2 diabetes. Although generally encouraging, these data only indicate a need for more evaluations of ginsengs safety and efficacy. Because of poor industry standardization, it is not known whether all ginsengs will affect blood glucose. In this regards some ginseng batches have demonstrated null effects while others have even raised postprandial glycemia. Clinical research should therefore focus on components involved in its glucose lowering effects.

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Effects of the Site-Specific Nitrogen Management on Economic Feasibility and Environmental Sustainability (토양특성(土壤特性)에 따른 질소시용(窒素施用)의 환경(環境) 경제적(經濟的) 효과(效果))

  • Kang, Choong-Kwan;Park, Joo-Sub;Lee, Sang-Yong;Kim, Han-Myeong
    • Korean Journal of Soil Science and Fertilizer
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    • v.34 no.1
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    • pp.42-54
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    • 2001
  • The use of nitrogen fertilizer in intensive agricultural production is of major concern due to its role on agricultural productivity and water quality. Crop production inputs on farm are usually applied at a uniform rate across an entire field. However, actual input requirements often vary within fields. The field variations in yield potential, soil moisture, soil N status, and the efficiency of fertilizer use, uniform application of crop production inputs does not allow optimum efficiency or profitability. This occurs because uniform application often results in areas of over- and under-application which may affect water quality and crop yield. This study used biophysical and economic models to assess the economic feasibility and water quality benefits of site specific nitrogen management for 10 soil types and 35 sample fields in Goodwater Creek watershed located near Centralia, Missouri. Results showed that the economic feasibility and water quality benefits of variable rate application were sensitive to the distribution of soil types within a field. Variable rate(VR) application was not uniformly more profitable than uniform rate(UR) application for the four agricultural systems evaluated and the water quality benefits were insubstantial relative to uniform application of N.

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Rainfall Intensity Estimation Using Geostationary Satellite Data Based on Machine Learning: A Case Study in the Korean Peninsula in Summer (정지 궤도 기상 위성을 이용한 기계 학습 기반 강우 강도 추정: 한반도 여름철을 대상으로)

  • Shin, Yeji;Han, Daehyeon;Im, Jungho
    • Korean Journal of Remote Sensing
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    • v.37 no.5_3
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    • pp.1405-1423
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    • 2021
  • Precipitation is one of the main factors that affect water and energy cycles, and its estimation plays a very important role in securing water resources and timely responding to water disasters. Satellite-based quantitative precipitation estimation (QPE) has the advantage of covering large areas at high spatiotemporal resolution. In this study, machine learning-based rainfall intensity models were developed using Himawari-8 Advanced Himawari Imager (AHI) water vapor channel (6.7 ㎛), infrared channel (10.8 ㎛), and weather radar Column Max (CMAX) composite data based on random forest (RF). The target variables were weather radar reflectivity (dBZ) and rainfall intensity (mm/hr) converted by the Z-R relationship. The results showed that the model which learned CMAX reflectivity produced the Critical Success Index (CSI) of 0.34 and the Mean-Absolute-Error (MAE) of 4.82 mm/hr. When compared to the GeoKompsat-2 and Precipitation Estimation from Remotely Sensed Information Using Artificial Neural Networks (PERSIANN)-Cloud Classification System (CCS) rainfall intensity products, the accuracies improved by 21.73% and 10.81% for CSI, and 31.33% and 23.49% for MAE, respectively. The spatial distribution of the estimated rainfall intensity was much more similar to the radar data than the existing products.

A Study on Condition Analysis of Revised Project Level of Gravity Port facility using Big Data (빅데이터 분석을 통한 중력식 항만시설 수정프로젝트 레벨의 상태변화 특성 분석)

  • Na, Yong Hyoun;Park, Mi Yeon;Jang, Shinwoo
    • Journal of the Society of Disaster Information
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    • v.17 no.2
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    • pp.254-265
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    • 2021
  • Purpose: Inspection and diagnosis on the performance and safety through domestic port facilities have been conducted for over 20 years. However, the long-term development strategies and directions for facility renewal and performance improvement using the diagnosis history and results are not working in realistically. In particular, in the case of port structures with a long service life, there are many problems in terms of safety and functionality due to increasing of the large-sized ships, of port use frequency, and the effects of natural disasters due to climate change. Method: In this study, the maintenance history data of the gravity type quay in element level were collected, defined as big data, and a predictive approximation model was derived to estimate the pattern of deterioration and aging of the facility of project level based on the data. In particular, we compared and proposed models suitable for the use of big data by examining the validity of the state-based deterioration pattern and deterioration approximation model generated through machine learning algorithms of GP and SGP techniques. Result: As a result of reviewing the suitability of the proposed technique, it was considered that the RMSE and R2 in GP technique were 0.9854 and 0.0721, and the SGP technique was 0.7246 and 0.2518. Conclusion: This research through machine learning techniques is expected to play an important role in decision-making on investment in port facilities in the future if port facility data collection is continuously performed in the future.