• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.9
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• pp.901-908
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• 2016

Edge is the basic characteristic of image, edge detection is very important in image processing applications and computer vision area. Many studies are being performed to detect these edges by domestic and foreign researchers. The conventional edge detection methods such as Roberts, Sobel, Prewitt, and Laplacian etc, which are using a fixed value of mask are widely used and morphological gradient which uses dilation and erosion among morphology process techniques is also widely used. But these methods does not detect edges well in the diagonal direction or gradually changing image parts. Accordingly, in this paper, the modified top-hat and bottom-hat transform algorithms which are detecting edges well in the parts of diagonal direction or gradually changing image are proposed. The proposed algorithms present the detected edge images compared with the conventional methods and are evaluated performance by using cosine similarity.

• Journal of Preventive Medicine and Public Health
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• v.32 no.2
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• pp.200-205
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• 1999

Objectives: This study was carried out to investigate the aluminum concentrations in blood, urine and drinking water, the factors which affect the concentrations and the role of silicon in patients who were taking antacid containing aluminum. Methods: We selected 122 peptic ulcer patients as cases and 144 healthy examinees as controls. Blood, urine, and drinking water were collected from the each study subject and we measured aluminum concentrations as well as silicon concentrations in the specimens. The factors including silicon affect on the aluminum concentrations were also analyzed, Results: 1. The mean duration of antacid administration was 12 months, and the mean daily and total amount of aluminum administration were 0.9 g and 304 g per each patient, respectively. 2. The blood and urine aluminum concentrations were significantly higher in the case. 3. The blood silicon concentration was significantly lower in the control group, and the urine silicon concentration was significantly higher in the case. 4. Urine aluminum concentration was significantly correlated with blood aluminum concentration (r=0.18), and urine silicon concentration was correlated with blood aluminum (r=0.19) and urine aluminum concentrations (r=0.13). 5. The longer the duration of antacid administration and the larger the total and daily amount of aluminum in the antacid were, the higher urine aluminum and silicon concentrations were, but not to a statistically significant degree. Conclusions: Blood and urine aluminum concentrations were higher in the ulcer patients. The authors suggest that follow-up studies of the patients who administered antacid with high aluminum content for long duration should be done.

• The Plant Pathology Journal
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• v.24 no.2
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• pp.101-111
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• 2008

The fungal genus Alternaria is comprised of many saprophytic and endophytic species, but is most well known as containing many notoriously destructive plant pathogens. There are over 4,000 Alternaria/host associations recorded in the USDA Fungal Host Index ranking the genus 10th among nearly 2,000 fungal genera based on the total number of host records. While few Alternaria species appear to have a sexual stage to their life cycles, the majority lack sexuality altogether. Many pathogenic species of Alternaria are prolific toxin producers, which facilitates their necrotrophic lifestyle. Necrotrophs must kill host cells prior to colonization, and thus these toxins are secreted to facilitate host cell death often by triggering genetically programmed apoptotic pathways or by directly causing cell damage resulting in necrosis. While many species of Alternaria produce toxins with rather broad host ranges, a closely-related group of agronomically important Alternaria species produce selective toxins with a very narrow range often to the cultivar level. Genes that code for and direct the biosynthesis of these host-specific toxins for the Alternaria alternata sensu lato lineages are often contained on small, mostly conditionally dispensable, chromosomes. Besides the role of toxins in Alternaria pathogenesis, relatively few genes and/or gene products have been identified that contribute to or are required for pathogenicity. Recently, the completion of the A. brassicicola genome sequencing project has facilitated the examination of a substantial subset of genes for their role in pathogenicity. In this review, we will highlight the role of toxins in Alternaria pathogenesis and the use of A. brassicicola as a model representative for basic virulence studies for the genus as a whole. The current status of these research efforts will be discussed.

• Horticultural Science & Technology
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• v.19 no.3
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• pp.348-351
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• 2001

'Saenara' released by National Horticultural Research Institute in 1997 is a mid-season apple cultivar with attractive red skin, high quality and high productivity. This cultivar originated from the cross between 'Spur EarliBlaze' and 'Spur Golden Delicious' at Suwon in 1981. It was first selected in 1992 and named 'Wonkyo Ga-08'. The regional adaptability test was carried out for 5 years from 1993 to 1997 at 7 different sites. 'Saenara' is medium in tree vigor and has a spreading tree form. It bears abundant flower buds on many spurs. It blossoms a day earlier than 'Spur Golden Delicious', 3 days later than 'Spur EarliBlaze'. Harvesting time of 'Saenara' is September 10, 140 days after full bloom at Suwon. Fruit shape is conical and skin color is bright red. Fruit weighs about 300 g and has $14.6^{\circ}Brix$ soluble solids content. It is susceptible to alternaria leaf spot (Alternaria mali Roberts).

• Journal of Korean Library and Information Science Society
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• v.7
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• pp.177-206
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• 1980

Public library legislation is the essential means of providing for all the citizen in modern society with a standard public library service. We can trace the origin of that back to the Public Libraries Act 1850 in England. This paper is reviewing all the measures concerning public libraries of England since then in order to find out some guidelines for revision of the Korean Library Law enacted in 1963. Although Public Libraries Act 1850 was an output of a series of social reform movement in the 19th century, it established first the provision of public library service su n.0, pported by public funds. However the Act had several restrictions hindering public library service from making progress. These are: 1. Adoptive legislation in nature 2. Limitation of the size of population and rate income 3. Small library authorities 4. Procedure for adoption by public meeting 5. Restrictions on the ways in which rate income might be spent 6. No governmental organization to direct or control for a standardized public library service 7. No cooperative schemes among libraries. Subsequent development was directed largely to removal of those limitations. The present Public Libraries Act 1964 as a model of public library legislation was enacted on the basis of such reports as Kenyon, McColvin, Roberts, and Bourdillon. All but the problem of small library authorities were removed with this new Act. The final object could be achieved by the Local Government Act 1974 which reorganized existing 383 small authorities into new 115 ones the average population of which was 280, 000. Now, McColvin's dream of 30 years could be fulfilled in the late 70's. He argued that the minimum size of population of a viable authority should be 300, 000. Although the effect of the 1964 Act on the development of public library services in England was great, there must be some considerations as to the provisions of public library objective, government funding for library services, free use of library materials to all regardless of residence, and placement of library committee within the authority.

• Journal of Korean Neurosurgical Society
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• v.29 no.1
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• pp.15-22
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• 2000

Objective : This study was undertaken to evaluate the benefits and risks of the stereotactic biopsy in brain lesions. We assessed the diagnostic accuracy and morbidity rate associated with the stereotactic biopsy. Methods : The authors present a review of 47 patients, who underwent stereotactic biopsy using Cosman-Roberts-Wells(CRW) stereotactic apparatus during last six years. Results : Target locations were supratentorial in 36 cases, infratentorial in 9 and multiple in 2. According to pathological diagnosis, the largest group was neoplasm(29) followed by infection(9), infarction(2), cyst(2), and non-specific(5). Definitive diagnosis could be made in 42 of 47 cases(89.4%). When the mass lesion had been suspected as neoplastic condition, the diagnostic rate was 96.7%(29/30). It was being much higher than that of non-neoplastic lesion, 76.5%(13/17). The treatment modality was changed in 15 cases(32%) because the result of stereotactic biopsy was different from clinical diagnosis. Subsequent craniotomy after stereotactic biopsy was then performed in 6 cases, and the pathological diagnoses were precisely coincident in all of these cases. There were two complications(4.3%) : One intratumoral hemorrhage in glioblastoma and a transient hemiparesis in benign astrocytoma. There was no mortality in this series. Conclusion : The precise histological verification is crucial to determine the adequate treatment modality in intracranial lesions. Stereotactic biopsy is a safe and accurate diagnostic procedure for intracranial lesions with a low complication rate.

• The Korean Journal of Pharmacology
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• v.24 no.2
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• pp.153-164
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• 1988

The potential role of endogenous opioid peptides (EOPS) in cardiovascular regulation has only recently been entertained. EOPS have been localized in brain, spinal cord, autonomic ganglia, particularly the adrenal gland, and many other peripheral tissues. There are at least five major types of opioid receptors; namely ${\mu},\;{\delta},\;k,\;{\sigma},\;and\;{\varepsilon}$ and Experimental evidence indicates that cardiovascular actions of the peptide are mediated primarily by ${\mu},\;{\delta}$ and k receptors, and that these receptor types may be allosterically coupled. In anesthetized rabbits met-enkephalin decreased blood pressure and heart rate, which closely paralleled a reduction in sympathetic discharge. Naloxone, but not naloxone methobromide, antagonized these effects, which suggests a central site of action of met-enkephalin. A number of autonomic agents, particularly adrenergic ${\alpha}$-and, ${\beta}-agonists$ and antagonists modify the cardiovascular actions of met-enkephalin. Experiments in reserpine-treated and adrenalectomized rats provide no evidence of sympathetic nervous system involvement in the pressor responses to intravenous injection of opioid peptides, but rather suggest a direct peripheral action. Finally, activation of a beta-endorphinergic pathway projecting from the arcuate nucleus to the nucleus tractos solitarii in rats can cause naloxone reversible hypotension and bradycardia. There is evidence to implicate this pathway in antihypertensive drug action and in the modulation of baroreflex activity.

• Korean Journal Plant Pathology
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• v.3 no.4
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• pp.270-276
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• 1987

The fifty percent effective concentration (EC50) and the minimum inhibitory concentration (MIC) of iprodione on the resistant isolates of Alternaria mali obtained from infected leaves in Kyeongsan region ranged $550\~1,310{\mu}g/ml$ and $33,800-39,800{\mu}g/ml$, respectively. Conidia germination of the resistant isolates reached $70\%$ on PSA added with iprodione, $500{\mu}g/ml$ When treated with $500{\mu}g/ml$ iprodione soon after the inoculation the diameters of lesions on apple fruits 7days after inoculation with the resistant isolates were 1.6-14.6mm but no lesions appeared on those inoculated with the sensitive isolates. A similar trend of responses with the sensitive isolates was shown to benomyl, chlorothalonil, garbenda, thiophanatemethyl and triademefon with the resistant isolates. One isolate among the resistant ones was cross resistance to captan and folpet that were effective to the sensitive isolates.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.10
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• pp.1496-1501
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• 2002

A $2{\times}3$ factorial arrangement of treatments was used in a completely randomized design to determine the effects of dietary Zn on performance and immune response of acutely endotoxemic growing pigs (n=96, mean BW=24.9 kg). Factors included 1) intramuscular injection of $10{\mu}g/kg$ BW of Escherichia coli lipopolysaccharide (LPS) or control and 2) supplemental Zn at 10, 50, or 150 ppm. Diets were fed beginning after weaning (initial body weight=7.6 kg) in the nursery and continued for 16 d into the grower phase. The basal corn-soybean meal grower diet contained 1% lysine and 34.3 ppm Zn. Pigs were acclimated for 12 d in the growerfinishing facility before LPS treatment on d 13. Gain, feed intake, and feed efficiency were unaffected by dietary Zn. Feed intake decreased (p<0.10) and gain/feed was greater (p<0.10) from d 13 to d 16 for pigs injected with LPS. Serum Zn and alkaline phosphatase activity increased (p<0.05) with increasing Zn levels. The febrile response to LPS peaked at 6 h post exposure and pigs were afebrile within 12 h. Rectal temperature was greater (p<0.05) in pigs receiving 50 and 150 ppm Zn than in pigs supplemented with 10 ppm Zn. In vivo cellular immune response, measured on d 13 by skin thickness response to phytohemagglutinin (PHA), was greater after 6 h (p<0.05) in pigs fed 10 ppm Zn and exposed to LPS compared to all other treatments, but was not affected at 12, 24 or 48 h. Zinc did not affect mitogen induced lymphocyte proliferation. Zinc supplemented at 50 or 150 ppm resulted in an enhanced febrile response in pigs subjected to iatrogenic endotoxemia, but did not affect pig performance or immune response measurements.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.47 no.1
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• pp.152-159
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• 2010

Existing character recognition algorithm recognize characters in simple conditional. It has the disadvantage that recognition rates often drop drastically when input document image has low quality, rotated text, various font or size text because of external noise or data loss. In this paper, proposes the optical character recognition algorithm which using bicubic interpolation method for the catalog retrieval when the input image has rotated text, blurred, various font and size. In this paper, applied optical character recognition algorithm consist of detection and recognition part. Detection part applied roberts and hausdorff distance algorithm for correct detection the catalog of book. Recognition part applied bicubic interpolation to interpolate data loss due to low quality, various font and size text. By the next time, applied rotation for the bicubic interpolation result image to slant proofreading. Experimental results show that proposal method can effectively improve recognition rate 6% and search-time 1.077s process result.