• Title/Summary/Keyword: Risk Assessment Techniques

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Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma: dosimetric comparison and risk assessment of solid secondary cancer

  • Bae, Sun Hyun;Kim, Dong Wook;Kim, Mi-Sook;Shin, Myung-Hee;Park, Hee Chul;Lim, Do Hoon
    • Radiation Oncology Journal
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    • v.35 no.1
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    • pp.78-89
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    • 2017
  • Purpose: To determine the optimal radiotherapy technique for gastric mucosa-associated lymphoid tissue lymphoma (MALToma), we compared the dosimetric parameters and the risk of solid secondary cancer from scattered doses among anterior-posterior/ posterior-anterior parallel-opposed fields (AP/PA), anterior, posterior, right, and left lateral fields (4_field), 3-dimensional conformal radiotherapy (3D-CRT) using noncoplanar beams, and intensity-modulated radiotherapy composed of 7 coplanar beams (IMRT_co) and 7 coplanar and noncoplanar beams (IMRT_non). Materials and Methods: We retrospectively generated 5 planning techniques for 5 patients with gastric MALToma. Homogeneity index (HI), conformity index (CI), and mean doses of the kidney and liver were calculated from the dose-volume histograms. Applied the Biological Effects of Ionizing Radiation VII report to scattered doses, the lifetime attributable risk (LAR) was calculated to estimate the risk of solid secondary cancer. Results: The best value of CI was obtained with IMRT, although the HI varied among patients. The mean kidney dose was the highest with AP/PA, followed by 4_field, 3D-CRT, IMRT_co, and IMRT_non. On the other hand, the mean liver dose was the highest with 4_field and the lowest with AP/PA. Compared with 4_field, the LAR for 3D-CRT decreased except the lungs, and the LAR for IMRT_co and IMRT_non increased except the lungs. However, the absolute differences were much lower than <1%. Conclusion: Tailored RT techniques seem to be beneficial because it could achieve adjacent organ sparing with very small and clinically irrelevant increase of secondary solid cancer risk compared to the conventional techniques.

Derivation of risk factors according to accident cases related to subway structures

  • Park, Hyun Chul;Park, Young Gon;Pyeon, Mu Wook;Kim, hyun ki;Yoon, Hee Taek
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.39 no.5
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    • pp.329-341
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    • 2021
  • This study derives the risk-Influence factors for subway structures, the basis for the transition from the current subway disaster recovery-oriented maintenance system to a preemptive disaster management system, to reduce risk factors for existing subway structures. To apply reasonable risk assessment techniques, risk influence factors for subway underground structures using statistical information(spatial information) and risk influence factors according to frequency of accidents were selected to derive the risk factors. The significant risk factors were verified through ground subsidence (SI: Subsidence Impact)-based correlation analysis. This process confirmed that the subsidence of the ground was a risk influence factor for the subway structure. The main result of this study is that derive the risk factors to improve the risk factors of subway structures due to the rapid increase in disaster risk factors. The derived risk factors that were expected to affect the depression around subway stations and track structures did not show a noticeable correlation, but the cause of this may be that there is no physical connection between them, but on the other hand, the accumulated data may not accurately record the surrounding depression. Accordingly, in order to evaluate the risk of depression around the station and track, more intensive observation and data accumulation around the structure are required.

Seismic Performance Evaluation Methodology for Nuclear Power Plants (원전 구조물의 내진성능 평가 방법론 고찰)

  • Ann, Hojune;Kim, Yousok;Kong, Jung Sik;Choi, Youngjin;Choi, Se Woon;Lee, Min Seok
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.14 no.2
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    • pp.32-40
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    • 2018
  • Since 2000, the frequency of earthquakes beyond the 5.0 magnitude quake has been increasing in the Korean peninsula. For instance, the 5.0-magnitude earthquake in Baekryong-do in 2003 has occurred, and recent earthquake with Gyeongju(2016) and Pohang(2017) measured respectively magnitude of 5.2 and 5.8 on the Richter scale. As results, the public concern and anxiety about earthquakes are increasing, and therefore it is necessarily required for social infrastructure to reinforce seismic design and energy production facilities directly related to the national economy and security. This study represents the analysis of seismic performance evaluation methodology such as Seismic Margin Assessment (SMA), Seismic Probabilistic Risk Assessment (SPRA), High Confidence Low Probability Failure (HCLPF) in nuclear power plants in order to develop optimal seismic performance improvement. Current methodologies to evaluate nuclear power plants are also addressed. Through review of the nuclear structure evaluation past and current trend, it contributes to be the basis for the improvement of evaluation techniques on the next generation of nuclear power plants.

Ultrafine Particle Toxicities, Current Measurement Techniques and Controls (Ultrafine Particle의 독성, 측정방법 및 관리)

  • Lee, Su-Gil;Kim, Seong-Soo
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.20 no.3
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    • pp.203-215
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    • 2010
  • This study is an overview of toxicities and measurement techniques of ultrafine particles (UFPs), and their exposure controls. UFPs are ubiquitous in many working situations. Exposure to UFPs is possibly causing adverse health symptoms including cardio-respiratory disease to humans. In order to measure exposure levels of airborne UFPs, there are current available measurement guidelines, instruments and other techniques (i.e. contour mapping, control banding). However, these risk assessment techniques including measurement techniques, controls and guidelines are dependent on background levels, metrics (e.g. size, mass, number, surface area, composition), environmental conditions and controls. There are no standardized measurement methods available and no generic and specific occupational exposure standards for UFPs. It is thought that there needs to be more effort to develop Regulations and Exposure Standards for generic UFPs should be based on more exposure data, health surveys, toxicological data and epidemiological data. A carefully considered hierarchy of controls can also reduce the maximum amount of airborne UFPs being emitted from diverse sources in industries.

Case Study on the Assessment of SIL Using FMEDA (FMEDA 기법을 적용한 SIL 등급 판정에 관한 사례연구)

  • Kim, Byung Chul;Kim, Young Jin
    • IE interfaces
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    • v.25 no.4
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    • pp.376-381
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    • 2012
  • As the number, complexity and interaction of electrical, electronic and programmable electronic (E/E/PE) systems increase, a growing emphasis has been placed on the concept of functional safety during product development. IEC 61508 provides guidelines and standardized procedures in the development of reliable and dependable E/E/PE systems to assure functional safety. Determining risk classes (i.e., safety integrity levels, SILs) associated to a specific E/E/PE item may be recognized as one of the most crucial activities in the product development per IEC 61508 since SILs are used to specify necessary safety requirements for achieving an acceptable residual risk. This article presents a case study on the assessment of SILs applying failure modes, effects and diagnostic analysis (FMEDA) from which failure rates may be derived for each important failure category by combining a standard FMEA with online diagnostic techniques.

Mathematical Evaluation of Response Behaviors of Indicator Organisms to Toxic Materials (지표생물의 독성물질 반응 행동에 대한 수리적 평가)

  • Chon, Tae-Soo;Ji, Chang-Woo
    • Environmental Analysis Health and Toxicology
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    • v.23 no.4
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    • pp.231-245
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    • 2008
  • Various methods for detecting changes in response behaviors of indicator specimens are presented for monitoring effects of toxic treatments. The movement patterns of individuals are quantitatively characterized by statistical (i.e., ANOVA, multivariate analysis) and computational (i.e., fractal dimension, Fourier transform) methods. Extraction of information in complex behavioral data is further illustrated by techniques in ecological informatics. Multi-Layer Perceptron and Self-Organizing Map are applied for detection and patterning of response behaviors of indicator specimens. The recent techniques of Wavelet analysis and line detection by Recurrent Self-Organizing Map are additionally discussed as an efficient tool for checking time-series movement data. Behavioral monitoring could be established as new methodology in integrative ecological assessment, tilling the gap between large-scale (e.g., community structure) and small-scale (e.g., molecular response) measurements.

Development of flood hazard and risk maps in Bosnia and Herzegovina, key study of the Zujevina River

  • Emina, Hadzic;Giuseppe Tito, Aronica;Hata, Milisic;Suvada, Suvalija;Slobodanka, Kljucanin;Ammar, Saric;Suada, Sulejmanovic;Fehad, Mujic
    • Coupled systems mechanics
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    • v.11 no.6
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    • pp.505-524
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    • 2022
  • Floods represent extreme hydrological phenomena that affect populations, environment, social, political, and ecological systems. After the catastrophic floods that have hit Europe and the World in recent decades, the flood problem has become more current. At the EU level, a legal framework has been put in place with the entry into force of Directive 2007/60/EC on Flood Risk Assessment and Management (Flood Directive). Two years after the entry into force of the Floods Directive, Bosnia and Herzegovina (B&H), has adopted a Regulation on the types and content of water protection plans, which takes key steps and activities under the Floods Directive. The "Methodology for developing flood hazard and risk maps" (Methodology) was developed for the territory of Bosnia and Herzegovina, following the methodology used in the majority of EU member states, but with certain modifications to the country's characteristics. Accordingly, activities for the preparation of the Preliminary Flood Risk Assessment for each river basin district were completed in 2015 for the territory of Bosnia and Herzegovina. Activities on the production of hazard maps and flood risk maps are in progress. The results of probable climate change impact model forecasts should be included in the preparation of the Flood Risk Management Plans, which is the subsequent phase of implementing the Flood Directive. By the foregoing, the paper will give an example of the development of the hydrodynamic model of the Zujevina River, as well as the development of hazard and risk maps. Hazard and risk maps have been prepared for medium probability floods of 1/100 as well as for high probability floods of 1/20. The results of LiDAR (Light Detection and Ranging) recording were used to create a digital terrain model (DMR). It was noticed that there are big differences between the flood maps obtained by recording LiDAR techniques in relation to the previous flood maps obtained using georeferenced topographic maps. Particular attention is given to explaining the Methodology applied in Bosnia and Herzegovina.

Hazard Analysis and Risk Assessments for Industrial Processes Using FMEA and Bow-Tie Methodologies

  • Afefy, Islam H.
    • Industrial Engineering and Management Systems
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    • v.14 no.4
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    • pp.379-391
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    • 2015
  • Several risk assessment techniques have been presented and investigated in previous research, focusing mainly on the failure mode and effect analysis (FMEA). FMEA can be employed to determine where failures can occur within industrial systems and to assess the impact of such failures. This research proposes a novel methodology for hazard analysis and risk assessments that integrates FMEA with the bow-tie model. The proposed method has been applied and evaluated in a real industrial process, illustrating the effectiveness of the proposed method. Specifically, the bowtie diagram of the critical equipment in the adopted plant in the case study was built. Safety critical barriers are identified and each of these is assigned to industrial process with an individual responsible. The detection rating to the failure mode and the values of risk priority number (RPN) are calculated. The analysis shows the high values of RPN are 500 and 490 in this process. A global corrective actions are suggested to improve the RPN measure. Further managerial insights have been provided.

A Study on Promoting the Efficiency of Aircraft System Safety Assessment (항공기 시스템 안전성평가 효율화 방안 연구)

  • Yoo, Seung-woo;Lee, Jong-hee
    • Journal of Aerospace System Engineering
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    • v.6 no.3
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    • pp.7-12
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    • 2012
  • The contents of aircraft system safety assessment vary depending on factors such as the complexity of the system, how critical the system is to flight safety, what volume of experience is available on the type of system and the novelty and complexity of the technologies being used. If the system safety assessment is to substantiate that the developed products are 'safe enough' to be taken into use, then the system safety assessment should be planned and managed to provide the necessary assurance that all relevant hazards and failure conditions have been identified and that all significant combinations of hazards and failures which could cause those conditions have been considered. The assessment must assist the designer and management in making decisions. It must make clear what the critical features of each system are and upon which special manufacturing techniques, inspection, testing, crew drills and maintenance practice they are critically dependent. This paper has prepared to study on promoting the efficiency of aircraft system safety assessment and to present how to compile system safety assessment strategy.

Project Schedule Risk Assessment Based on Bayesian Nets (베이지안넷 기반의 프로젝트 일정리스크 평가)

  • Sung, Hongsuk;Park, Chulsoon
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.39 no.1
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    • pp.9-16
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    • 2016
  • The project schedule risk in the engineering and facility construction industry is increasingly considered as important management factor because the risks in terms of schedule or deadline may significantly affect the project cost. Especially, the project-based operating companies attempt to find the best estimate of the project completion time for use at their proposals, and therefore, usually have much interest in accurate estimation of the duration of the projects. In general, the management of projects schedule risk is achieved by modeling project schedule with PERT/CPM techniques, and then performing risk assessment with simulation such as Monte-Carlo simulation method. However, since these approaches require the accumulated executional data, which are not usually available in project-based operating company, and, further, they cannot reflect various schedule constraints, which usually are met during the project execution, the project managers have difficulty in preparing for the project risks in advance of their occurrence in the project execution. As these constraints may affect time and cost which role as the crucial evaluation factors to the quality of the project result, they must be identified and described in advance of their occurrence in the project management. This paper proposes a Bayesian Net based methodology for estimating project schedule risk by identifying and enforcing the project risks and its response plan which may occur in storage tank engineering and construction project environment. First, we translated the schedule network with the project risks and its response plan into Bayesian Net. Second, we analyzed the integrated Bayesian Net and suggested an estimate of project schedule risk with simulation approach. Finally, we applied our approach to a storage tank construction project to validate its feasibility.