• 제목/요약/키워드: Rhenium

검색결과 64건 처리시간 0.027초

NUCLEAR DATA MEASUREMENT OF 186RE PRODUCTION VIA VARIOUS REACTIONS

  • Bidokhti, Pooneh Saidi;Sadeghi, Mahdi;Fateh, Behrooz;Matloobi, Mitra;Aslani, Gholamreza
    • Nuclear Engineering and Technology
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    • 제42권5호
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    • pp.600-607
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    • 2010
  • Rhenium-186, having a half-life of 90.64 h, is an important radionuclide, used in metabolic radiotherapy and radio immunotherapy. $^{186}Re$ hydroxyethylidene diphosphonate (HEDP) is a new compound used for the palliation of painful skeletal metastases. Its production is achieved via charged-particle-induced reactions; the data are available in EXFOR library. For the work discussed in this paper, production of $^{186}Re$ was done via $^{nat}W(p,n)^{186}Re$ nuclear reaction. Pellets of $^{nat}W$ were used as targets and were irradiated with 15, 17.5, 20, 22.5, 25 MeV proton beams at 5 ${\mu}A$ current. The radiochemical separation was performed by the ion exchange chromatography method. The production yield achieved at 25 MeV was 1.91 $MBq{\cdot}{\mu}A^{-1}{\cdot}h^{-1}$. Excitation functions for the $^{186}Re$ radionuclide, via $^{186}W(p,n)^{186}Re$ and $^{186}W(d,2n)^{186}Re$ reactions were calculated by ALICE-ASH and TALYS-1.0 codes to validate and fit the experimental data and to obtain a recommended set of data for $^{186}W(p,n)^{186}Re$ reaction. Required thickness of the targets was obtained by SRIM code for each reaction.

고성능 로켓노즐 및 추력기용 내열부품 현황 (Perspectives on the Hot Components for Rocket Nozzle and Thrusters)

  • 임성택;김중근;강윤구;김형원;김연철
    • 한국추진공학회:학술대회논문집
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    • 한국추진공학회 2008년도 제31회 추계학술대회논문집
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    • pp.67-71
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    • 2008
  • 추력조정이 유연한 차세대 고체추진기관 그리고 위성제어용 차세대 비냉각 액체엔진 소형추력기는 $2500^{\circ}C$급의 가혹한 작동조건에서 비삭마, 내열 내산화와 같은 내구성을 가진 내열부품을 요구하고 있다. 본 연구에서는 차세대 추진기관의 작동조건을 제시하고 그에 맞는 내열부품의 국내외 기술현황을 조사하였다. 또한 레늄(Re)을 기본으로하는, 고체 및 액체추진기관에 동시 적용이 가능한 $2500^{\circ}C$급 초고온 장수명 추력기(thruster) 내열부품의 국내연구 필요성과 방향을 제시하였다.

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188Re Labeled liver therapeutic drugs for hepatic carcinoma (HCC)

  • Seelam, Sudhakara Reddy;Banka, Vinay Kumar;Lee, Yun-Sang;Jeong, Jae Min
    • 대한방사성의약품학회지
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    • 제5권1호
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    • pp.26-35
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    • 2019
  • $^{188}Re$ is one of the most readily available generator derived and useful radionuclides for therapy emitting ${\beta}^-$ particles (2.12 MeV, 71.1% and 1.965 MeV, 25.6%) and imageable gammas (155 keV, 15.1%). The $^{188}W/^{188}Re$ generator is an ideal source for the long term (4-6 months) continuous availability of no carrier added (NCA) $^{188}Re$ suitable for the preparation of radiopharmaceuticals for radionuclide therapy. Rhenium-188 has been used for the preparation of therapeutic radiopharmaceuticals for the management of diseases such as bone metastasis, rheumatoid arthritis and primary cancers. Several early phase clinical studies using radiopharmaceuticals based on $^{188}Re$ -labeled phosphonates, antibodies, peptides, lipiodol and particulates have been reported. In this review, we addressed the current development status of $^{188}Re$ radiopharmaceuticals for liver cancer therapy and their applications.

DA-7911, rhenium-188 ($Re^{188}$) tin colloid. as a strong candidate agent for radiation synovectomy

  • Shin, Chang-Yell;Jung, Mi-Young;Lee, In-Ki;Son, Mi-Won;Kim, Soon-Hoe;Kim, Won-Bae
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.252-252
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    • 2002
  • Radiation synovectomy is an useful alternative treatment to rheumatoid arthritis and Re$\^$188/ is suggested as an ideal radiopharmaceutical agents because beta ray (2.1 MeV) emitted from Re$\^$188/ is appropriate for synovial cell ablation and gamma ray (155 KeV) is ideal for dosimetry. Its' ideal particle size (2-5 mm) was achieved by conjugation with tin-colloid, In this study, we investigated the toxicity, stability and biodistribution to evaluate the suitability of DA-7911 as a synovectomy agent. (omitted)

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Novel Electrical Dopants for High Performance OLEDs

  • Leem, Dong-Seok;Lee, Jae-Hyun;Kim, Jang-Joo
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.1311-1314
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    • 2008
  • We have developed new electrical dopants of rhenium oxide ($ReO_3$) and cupper iodide (CuI) as p-dopants and rubidium carbonate ($Rb_2CO_3$) as an n-dopant, respectively. $ReO_3$ has advantage of low temperature evaporation (about $300^{\circ}C$) with enhanced device stability. Various kinds of high performance organic light emitting diodes have been realized, including bottom emission, tandem, and top-emission OLEDs.

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Tungsten Carbide 코어 표면에 코팅 된 Re-Ir 박막 특성 (Characteristics of Re-Jr Coating Thin Film on Tungsten Carbide Core Surface)

  • 이호식;박용필;천민우
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2010년도 하계학술대회 논문집
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    • pp.139-139
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    • 2010
  • Rhenium-Iridium(Re-Ir) thin films were deposited onto the tungsten carbide(WC) molding core by sputtering system. The Re-Ir thin films on tungsten carbide molding core were analyzed by scanning electron microscope(SEM) and surface roughness. The Re-Ir coating technique has been intensive efforts in the field of coating process because the coating technique and process have been their feature, like hardness, high elasticity, adrasion resistance and mechanical stability and also have been applied widely the industrial and biomedical areas. In this report, tungsten carbide(WC) molding core was manufactures using high performance precision machining and the efforts of Re-Ir coating on the surface roughness.

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Rhenium-188 생산 (Production of Re-188)

  • 양승대;서용섭;김상욱;임상무
    • 대한핵의학회:학술대회논문집
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    • 대한핵의학회 1999년도 제38차 춘계학술대회
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    • pp.189-192
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    • 1999
  • $^{188}Re$ (${\beta}^-=2.2$ MeV; ${\gamma}^-$=155 keV; $T_{1/2}$=16.9 hours) is an attractive therapeutic radioisotope which is produced from decay of reactor-produced tungsten-188 parent ($T_{1/2}$=69 days). $^{188}W$ has been produced from the double neutron capture reaction of $^{186}W.\;^{188}Re$ can be easily obtained by elution of saline on alumina based $^{188}W/^{188}Re$ generator, which is commercially available. Complexes labelled with $^{188}Re$ have been developed for the radiotherapy treatment of diseases because of the desirable nuclear properties of the radioisotope and it's chemical properties similar to those of technetium, a well established diagnostic agent.

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Feasibility of Using Graphite Powder to Enhance Uranium Ion Intensity in Thermal Ionization Mass Spectrometry (TIMS)

  • Park, Jong-Ho
    • Mass Spectrometry Letters
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    • 제7권4호
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    • pp.102-105
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    • 2016
  • This study explored the feasibility of using a carburization technique to enhance the ion intensity of isotopic analysis of ultra-trace levels of uranium using thermal ionization mass spectrometry (TIMS). Prior to fixing uranium samples on TIMS filaments, graphite powder suspended in nitric acid was deposited on rhenium filaments. We observed an enhancement of $^{238}U^+$ intensity by a factor of two when carburization was used, and were able to roughly optimize the amount of graphite powder necessary for carburization. The positive shift in heating current when evaporating filaments upon carburization implies that uranium was chemically altered by carburization, when compared to normal fixation processes. The good agreement between our method and known standards down to an ultra-trace level shows that the proposed technique can be applied to isotopic uranium analysis down to abundances of ~10 pg.