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http://dx.doi.org/10.5516/NET.2010.42.5.600

NUCLEAR DATA MEASUREMENT OF 186RE PRODUCTION VIA VARIOUS REACTIONS  

Bidokhti, Pooneh Saidi (Faculty of Engineering, Research and Science Campus, Islamic Azad University)
Sadeghi, Mahdi (Agricultural, Medical & Industrial Research School)
Fateh, Behrooz (Agricultural, Medical & Industrial Research School)
Matloobi, Mitra (Agricultural, Medical & Industrial Research School)
Aslani, Gholamreza (Agricultural, Medical & Industrial Research School)
Publication Information
Nuclear Engineering and Technology / v.42, no.5, 2010 , pp. 600-607 More about this Journal
Abstract
Rhenium-186, having a half-life of 90.64 h, is an important radionuclide, used in metabolic radiotherapy and radio immunotherapy. $^{186}Re$ hydroxyethylidene diphosphonate (HEDP) is a new compound used for the palliation of painful skeletal metastases. Its production is achieved via charged-particle-induced reactions; the data are available in EXFOR library. For the work discussed in this paper, production of $^{186}Re$ was done via $^{nat}W(p,n)^{186}Re$ nuclear reaction. Pellets of $^{nat}W$ were used as targets and were irradiated with 15, 17.5, 20, 22.5, 25 MeV proton beams at 5 ${\mu}A$ current. The radiochemical separation was performed by the ion exchange chromatography method. The production yield achieved at 25 MeV was 1.91 $MBq{\cdot}{\mu}A^{-1}{\cdot}h^{-1}$. Excitation functions for the $^{186}Re$ radionuclide, via $^{186}W(p,n)^{186}Re$ and $^{186}W(d,2n)^{186}Re$ reactions were calculated by ALICE-ASH and TALYS-1.0 codes to validate and fit the experimental data and to obtain a recommended set of data for $^{186}W(p,n)^{186}Re$ reaction. Required thickness of the targets was obtained by SRIM code for each reaction.
Keywords
Rhenium-186; Tungsten-186; Cross-Section; Nuclear Model Calculation; Production;
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