• Korean Journal of Construction Engineering and Management
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• v.22 no.1
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• pp.13-26
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• 2021

To promote the off-site construction (OSC) in Korea, technical innovation applied to each phase, such as design, engineering, factory production, and site assembly, is important and equally necessary is the development of management and operation methods that are different from existing construction production methods. However, the current OSC-related studies in Korea are conducted from the technical development viewpoints, such as construction methods. Additionally, few studies have been conducted to derive a management measure for successful OSC projects. Therefore, studies to derive a management measure based on a clear understanding of the core success factors of OSC projects are required. This study aims to analyze several studies related to the success factors of OSC projects conducted overseas and to show its core implications for the successful management of OSC projects in Korea. We expect this study to improve the viability of OSC projects, which will be expanded in Korea in the future.

• Archives of Plastic Surgery
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• v.49 no.4
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• pp.494-500
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• 2022

Background Seroma formation is the most common donor site complication following autologous breast reconstruction, along with hematoma. Seroma may lead to patient discomfort and may prolong hospital stay or delay adjuvant treatment. The aim of this study was to compare seroma rates between the deep inferior epigastric perforator (DIEP), transverse musculocutaneous gracilis (TMG), and superior gluteal artery perforator (SGAP) donor sites. Methods The authors conducted a retrospective single-center cohort study consisting of chart review of all patients who underwent microsurgical breast reconstruction from April 2018 to June 2020. The primary outcome studied was frequency of seroma formation at the different donor sites. The secondary outcome evaluated potential prognostic properties associated with seroma formation. Third, the number of donor site seroma evacuations was compared between the three donor sites. Results Overall, 242 breast reconstructions were performed in 189 patients. Demographic data were found statistically comparable between the three flap cohorts, except for body mass index (BMI). Frequency of seroma formation was highest at the SGAP donor site (75.0%), followed by the TMG (65.0%), and DIEP (28.6%) donor sites. No association was found between seroma formation and BMI, age at surgery, smoking status, diabetes mellitus, neoadjuvant chemotherapy, or DIEP laterality. The mean number of seroma evacuations was significantly higher in the SGAP and the TMG group compared with the DIEP group. Conclusion This study provides a single center's experience regarding seroma formation at the donor site after microsurgical breast reconstruction. The observed rate of donor site seroma formation was comparably high, especially in the TMG and SGAP group, necessitating an adaption of the surgical protocol.

• Journal of People, Plants, and Environment
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• v.23 no.3
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• pp.347-362
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• 2020

Background and objective: It is difficult to conclusively determine the exact cause of tree defects since multiple causes are involved such as climate change, plantation, tree quality and planting time, construction, planting base, drainage, sunshine conditions, maintenance, and microclimate. The data related to landscaping construction defects are scattered or fragmented by companies and years, but not managed systematically by the defect information management system. Most of the earlier studies associated with tree defects in apartment complexes suggested defect rates after examining tree defects in the completed construction site and proposed fragmentary and subjective conclusions about the causes of defects observed in trees with high defect rates. It is proposed to continue to conduct studies on the establishment and analysis of systematic databases to identify the exact causes of tree defects and measures to improve, and the need to accumulate systematic data in the construction process where many defects arises. This study was conducted to reduce the defects of trees planted in apartment complexes. Methods: Main factors related to tree defects were subdivided based on the results of literature review and a defect investigation at the completion site, and tree history management items were selected and subdivided during the construction stage. Results: The criteria for the preparation of subdivided items were obtained, and the tree history management checklist was written for the site under actual construction and a systematic database was established. Items that are categorized based to the causes of defects include the location of nurseries, date, tree quality, site conditions, planting techniques, microclimates, and maintenance. Conclusion: This study suggested tree history management items based on the tree defects that can be identified at the construction stage and applied them to the selected study site, which differentiates this study from earlier studies. It will be necessary to conduct a comprehensive and objective time series analysis on tree defects that occur over time by continuously monitoring and collecting data after construction.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.43 no.6
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• pp.831-839
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• 2023

The purpose of this study is to quickly collect and analyze information generated in real-time at disaster sites to propose an integrated plan for an on-site support system that can support accurate disaster site situation identification and decision-making, and to review field applicability through prototype simulation. Accordingly, information collection, sharing, and convergence technologies that can be used at disaster sites were reviewed, and a plan for integrating a smart disaster site support system that can create an efficient flow of information resources and information necessary for the entire stage of disaster management was presented. In order to examine the possibility of operating the system with a prototype manufactured based on the integration plan, simulations were conducted based on the storm and flood disaster scenario, and it was confirmed that various functions in the system were implemented normally and displayed on the GIS situation board. Through this study, it is expected that efficient and active disaster response will be possible in a rapidly changing disaster environment.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.49-66
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• 1999

Polypharmacotherapy, both psychotropic and nonpsychotropic, is widespread in various situations including psychiatric hospitals and general hospitals. As the clinical practice of using more than one drug at a time increase, the clinician is faced with ever-increasing number of potential drug interactions. Although many interactions have little clinical significances, some may interfere with treatment or even be life-threatening. The objective of this review is evaluation for drug-drug interactions often encountered in psychiatric consultation. Drug interactions can be grouped into two principal subdivisions : pharmacokinetic and pharmacodynamic. These subgroups serve to focus attention on possible sites of interaction as a drug moves from the site of administration and absorption to its site of action. Pharmacokinetic processes are those that include transport to and from the receptor site and consist of absorption, distribution on body tissue, plasma protein binding, metabolism, and excretion. Pharmacodynamic interactions occur at biologically active sites. In psychiatric consultation, these two subdivisions of drug interactions between psychotropic drugs and other drugs are likely to happen. We gathered informations of the drugs used in physically ill patients who are consulted to psychiatric department in Korea University Hospital. And we reviewed the related literatures about the drug-drug interactions between psychotropic drugs and other drugs.

• Journal of Plant Biotechnology
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• v.37 no.3
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• pp.283-291
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• 2010

Vaccine is one of the best known and most successful applications of immunological theory to human health and it protects human life through inducing the immune response in systemic compartment. However, when we consider the fact that mucosal epithelium is exposed to diverse foreign materials including viruses, bacteria, and food antigens and protects body from entry of unwanted materials using layer of tightly joined epithelial cells, establishing the immunological barrier on the lining of mucosal surfaces is believed to be an effective strategy to protect body from unwanted antigens. Unfortunately, however, oral mucosal site, which is considered as the best target to induce mucosal immune response due to application convenience, is prone to induce immune tolerance rather than immune stimulation. Since intestinal epithelium is tightly organized, a prerequisite for successful mucosal vaccination is delivery of antigen to mucosal immune induction site including a complex system of highly specialized cells such as M cells. Consequently, development of efficient mucosal adjuvant capable of introducing antigens to mucosal immune induction site and overcome oral tolerance is an important subject in oral vaccine development. In this review, various approaches on the development of oral mucosal adjuvants being suggested for effective oral mucosal immune induction.

• Journal of Yeungnam Medical Science
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• v.5 no.1
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• pp.135-139
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• 1988

The primary malignat melanoma of the nasal cavity and paranasal sinuses is extemely rare and accounts for only between 0.6 and 2.5% of the total 'number of malignat melanoma at all sites. In the nose, the left side is involved in 60% of cases and the most frequent site is the septum followed by the inferior and middle turbinates. In the sinuses, the maxillary sinus is the site of origin in 80% of cases, followed by ethmoid sinus. The tumors are sessile or polypoid, with variable color such as pink. white, brown or black. Of all tumors, 10~30% are amelanotic, requiring special stains for melanin. When primary site of melanoma is mucosal origin. treatment of primary lesion is often hampered by anatomic retrictions and large size, which results from the delayed diagnosis caused by their location. We report 4 cases of primary malignant melanoma of nasal cavity with review of literature.

• International Commerce and Information Review
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• v.2 no.2
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• pp.69-95
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• 2000

무역거래의 패턴이 최근 크게 변화하고 있는데, 기존 무역거래방식에서 인터넷무역방식으로 그 비중이 확대되면서 인터넷 무역거래알선사이트에 관한 관심과 활용도가 점차 높아지고 있으며 특히 무역거래알선사이트의 구축 및 운영은 국내외의 무역 유관기관과 지방자치 단체, 대기업 종합무역상사 및 개별기업을 중심으로 활발히 진행되고 있다. 이에 실제 우리 나라 무역업체들의 사이트 이용 및 현황과 이용만족도 조사를 위해 설문조사를 한 결과, 현재까지 무역업체들이 가장 선호하는 사이트는 무역 유관기관이 운영하는 사이트들이다. 또한 실제 무역거래알선사이트를 이용한 결과와 관련하여 거래알선사이트 제공서비스에 대한 만족은 대상 업체 중 불과 17.9%의 낮은 수준으로서 이렇듯 낮은 만족도를 보이는데는 다음과 같은 문제점들이 있었다. 즉, 정보 인프라 측면에서의 관련정책의 분산, 보안 인프라의 우려, 오프라인 상의 결제 및 세금문제, 인터넷무역 관련 국제협력문제 등을 들 수 있으며, 무역업체의 측면에서는 전문인력의 부족, 최고경영자의 정보화 인프라에 대한 마인드 부족과 업체내의 웹 기반 환경 구축 미흡 등을 들 수 있다. 이상의 문제점들을 개선하기 위한 활성화방안을 살펴보면 첫째, 거래정보 보호기술의 육성 둘째, 무역거래알선사이트의 적극적인 국내외 홍보 셋째, 무역거래알선사이트 관련 분쟁 신용조회 등의 통합관리 넷째, 사이트관련 온라인과 오프라인상의 제반환경 개선 및 국제거래 규약 개선 다섯째, 무역거래알선시스템의 효율성제고를 위한 전문인력 양성 및 교육훈련 강화 등이 절실히 요망되고 있다.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.6 no.1
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• pp.53-58
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• 2020

Pretargeting is a two-component strategy often used for tumor targeting to enhance the tumor-to-background ratio in cancer diagnosis as well as therapy. In the multistep strategy, the highly specific unlabeled monoclonal antibodies (mAbs) with the reactive site is allowed to get localized at tumor site first, and then small and fastclearing radiolabeled chelator with counter reactive site is administered which covalently attaches to mAbs via inverse electron demand Diels-Alder reaction (IEDDA). The catalyst-free IEDDA cycloaddition reaction between 1,2,4,5-tetrazines and strained alkene dienophiles aid with properties like selective bioconjugation, swift and high yielding bioorthogonal reactions are emergent in the development of radiopharmaceutical. Due to its fast pharmacokinetics, the in vivo formed radioimmunoconjugates can be imaged at earlier time points by short-lived radionuclides like ¹⁸F and ⁶⁸Ga; it can also reduce radiation damage to the normal cells. Ultimately, this review elucidates the updated status of pretargeting based on antibodies and IEDDA for tumor diagnosis (PET and SPECT) and therapy.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.27 no.1
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• pp.39-47
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• 2005

The purpose of this study is to review the prognosis of the TG Osseotite implant(3i Co, USA) placed in partial edentulous area of oral cavity and to suspect the possible causes leading to failure. 124 TG Osseotite implants that had been inserted between 2000 - 2002 were followed up for 2 years(avg : 9.5 months) in function. Medical records, and radiographs were evaluated and analyzed by the over all success rate, gender and age factor, general disease, implant fixture length and diameter, implant site, bone density, and various surgical methods. Chi square test was used statistically. Of the 124 TG Osseotite implants, 9 implants(7.3%) were removed in early phase and 3 implants(2.4%) were in late phase. The cumulative survival rate was 90.2%. The failure of the TG Osseotite implant was closely related with the use of bone graft techniques such as sinus elevation or immediate implantation and not with the age, sex, general disease, implant site, bone density of implanted site. The failure of the TG Osseotite implant was well developed when it was the wide type of implant and it was inserted for single tooth replacement. The developement of peri-implantitis was the most important factor in the failure of the TG Osseotite implant.