• 한국결정성장학회지
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• 제16권4호
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• pp.133-140
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• 2006

The growth characteristics and properties of large size $SrAlF_5$ single crystals are described and compared with those of $BaMgF_4$. Transmission spectra in the vacuum ultraviolet wavelength region indicate a high transparency of $SrAlF_5$ (about 90% without considering surface reflection loses) down to 150 nm, on contrast to the optical loses observed for $BaMgF_4$. The ferroelectric character of $SrAlF_5$ is evidenced by the reversal of the spontaneous polarization in a hysteresis loop. The higher potential of $SrAlF_5$ in comparison with $BaMgF_4$ for the realization of all-solid-state lasers in the ultraviolet wavelength region by the quasi-phase matching (QPM) technique is pointed out. $SrAlF_5$, besides a higher grade of transparency, shows a nonlinear effective coefficient similar to that of quartz and uniaxial nature, on contrast to the one order smaller nonlinear coefficient and biaxial character of $BaMgF_4$. The refractive index of $SrAlF_5$ from the ultraviolet to the near-infrared wavelength region is measured by the minimum deviation method. The Sellmeier and Cauchy coefficients are obtained from the fits to the curves of the ordinary and extraordinary refractive indices, and the grating period for the first order QPM is estimated as a function of the wavelength. The poling periodicity for 193 nm SHG from 386 nm is $4{\mu}m$.

• 한국마린엔지니어링학회:학술대회논문집
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• 한국마린엔지니어링학회 2005년도 후기학술대회논문집
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• pp.156-157
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• 2005

Gas hydrate is ice-like crystalline lattice, formed at appropriate temperature and pressure, in which gas molecules are trapped. It is worldwide popular interesting subject as a potential energy. In korea, a seismic survey for gas hydrate have performed over the East sea by the KIGAM since 1997. In this paper, we had conducted numerical and physical modeling experiments for seismic properties on gas hydrate with field data which had been acquired over the East sea in 1998. We used a finite difference seismic method with staggered grid for 2-D elastic wave equation to generate synthetic seismograms from multi-channel surface seismic survey, OBC(Ocean Bottom Cable) and VSP(Vertical Seismic Profiling). We developed the seismic physical modeling system which is simulated in the deep sea conditions and acquired the physical model data to the various source-receiver geometry. We carried out seismic complex analysis with the obtained data. In numerical and physical modeling data, we observed the phase reversal phenomenon of reflection wave at interface between the gas hydrate and free gas. In seismic physical modeling, seismic properties of the modeling material agree with the seismic velocity estimated from the travel time of reflection events. We could easily find out AVO(Amplitude Versus Offset) in the reflection strength profile through seismic complex analysis.

• International Journal of Oral Biology
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• 제34권3호
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• pp.151-155
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• 2009

The role of $Cl^-$ channels in regulatory volume decrease (RVD) in human salivary gland acinar cells was examined using a whole-cell patch clamp technique. Human tissues were obtained from healthy volunteers or from patients with oromaxillofacial tumors. During the measurements, $K^+$-free solutions were employed to eliminate contamination of whole-cell conductance by $K^+$ currents. When the cells were exposed to a 70% hypotonic solution, outward-rectifying currents, which were not observed in the resting state, were found to have significantly increased both in human labial and parotid gland acinar cells. The amplitudes of the currents were reduced in a low $Cl^-$ bath solution. Furthermore, the addition of $100{\mu}M$ 5-Nitro-2- (3-phenyl propylamino) benzoic acid (NPPB) or $100{\mu}M$ 4,4'-diisothio cyanatostilbene-2,2'-disulphonic acid (DIDS), known to partially block $Cl^-$ channels, significantly inhibited these currents. Its outward-rectifying current profile, shift in reversal potential in a low $Cl^-$ bath solution and pharmacological properties suggest that this is a $Ca^{2+}$-independent, volume activated $Cl^-$ current. We conclude therefore that volume activated $Cl^-$ channels play a putative role in RVD in human salivary gland acinar cells.

• The Korean Journal of Physiology and Pharmacology
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• 제20권5호
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• pp.525-531
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• 2016

The analgesic mechanism of opioids is known to decrease the excitability of substantia gelatinosa (SG) neurons receiving the synaptic inputs from primary nociceptive afferent fiber by increasing inwardly rectifying $K^+$ current. In this study, we examined whether a ${\mu}$-opioid agonist, [D-Ala2,N-Me-Phe4, Gly5-ol]-enkephalin (DAMGO), affects the two-pore domain $K^+$ channel (K2P) current in rat SG neurons using a slice whole-cell patch clamp technique. Also we confirmed which subtypes of K2P channels were associated with DAMGO-induced currents, measuring the expression of K2P channel in whole spinal cord and SG region. DAMGO caused a robust hyperpolarization and outward current in the SG neurons, which developed almost instantaneously and did not show any time-dependent inactivation. Half of the SG neurons exhibited a linear I~V relationship of the DAMGO-induced current, whereas rest of the neurons displayed inward rectification. In SG neurons with a linear I~V relationship of DAMGO-induced current, the reversal potential was close to the $K^+$ equilibrium potentials. The mRNA expression of TWIK (tandem of pore domains in a weak inwardly rectifying $K^+$ channel) related acid-sensitive $K^+$ channel (TASK) 1 and 3 was found in the SG region and a low pH (6.4) significantly blocked the DAMGO-induced $K^+$ current. Taken together, the DAMGO-induced hyperpolarization at resting membrane potential and subsequent decrease in excitability of SG neurons can be carried by the two-pore domain $K^+$ channel (TASK1 and 3) in addition to inwardly rectifying $K^+$ channel.

• 한국실내디자인학회논문집
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• 제18권6호
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• pp.44-51
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• 2009

Various and complex cultural phenomena have led to many changes in the space. The concept of unconsciousness, among others, and experimental expression technique and the concepts from surrealism that rather attaches great importance to contingency than intentional attempt have been employed in the space. The abstract expression as expressional characteristics of surrealism makes the space ambiguous through the concept of automatism using the approach of indeterminism and double image expression, and represents the space providing diversity through the dualism. In contrast, objective expression, which was based on depaysement, generates the tension and expresses the dramatic situation in such a way and manner which are intentional, distorted transformed, together with heterogenous meanings aligned through the reversal appeared in the techniques of collage and paranoiac-critical method. However if such space accommodating the expressional characteristics of surrealism is approached as superficial concept in analyzing the human's inner consciousness and imaginary society, expression of the ultimate concept contained in the expressional characteristics of surrealism can hardly be achieved. Hence, the spatial analysis from the semiotic approach, instead of unilateral method aimed to convey the meaning only, which creates the signification, was adopted. The study, as effective approach to the space accommodating the expressional characteristics of surrealism, was intended systematically evaluate the concreteness of understanding and generation of meaning through the semiotic method. Greimas' semiotic square analysis to the space plays the important role in generating the spatial meaning, as well as is needed for objective analysis of the importance of various characteristics and methodology which the space contains through the expressional characteristics of surrealism.

• 한국정보통신학회논문지
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• 제20권11호
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• pp.2085-2092
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• 2016

IC 기판의 가장 중요한 성질들의 하나는 넓은 영역에 걸쳐 균일해야만 한다는 것이다. 웨이퍼 결함 분석의 다양한 물리적 접근 방법 중에서 적외선 조사 기법에 특별한 관심이 모아지고 있다. 특히, 높은 공간적 분해력을 가지고 있는 근적외선 흡수 방법은 반-절연 GaAs 내의 결함들을 직접적으로 관찰하는데 이용되고 있다. 적외선 전송에 기초를 둔 이 기법은 신속하고 비파괴 적이다. 이 방법은, 직접적으로 GaAs 반도체의 적외선 영상은 결함의 광흡수 작용에 기인한 것임을 밝히고 있다. 반-절연 GaAs 내의 EL2에 관련된, 비 균일 적으로 분포된 결함들의 적외선 흡수 영상에서 콘트라스트가 반전되는 현상에 대해 새로운 모델을 제시하고 있다. 저온 포토퀀칭 실험은, 직접적인 방법으로, GaAs 웨이퍼의 콘트라스트 반전 영상은 밴드갭의 지엽적인 변동이나 전하 재분포에 의한 것이 아니라 흡수와 산란의 두 메커니즘에 의한 것임을 증명하고 있다.

• Fisheries and Aquatic Sciences
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• 제26권1호
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• pp.48-57
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• 2023

One of the ways to increase the production for aquaculture is through the cultivation of monosexuals by ensuring genital reversal from which energy for reproduction is diverted towards growth. Masculinization has been identified as one of the most prominent techniques, where sex development was directed from female to male. This approach only altered the phenotype and not the genotype. The red claw crayfish (Cherax quadricarinatus) was a relatively new commercial commodity, and the males were known to grow faster than females. Hence, it was proposed to use monocultures comprising an all-male population to increase yield using steroid hormone, synthetic 17α-methyltestosterone. However, this technique generated residues that detrimentally affect human health, the environment, and cultivated organisms. Therefore, finding new safe natural steroid sources was essential, and one of which is exploring of natural hormones extracted from the viscera of sea cucumbers (Holothuria scabra Jaeger). This study focused on the determination of male formation and testosterone levels among juvenile crayfish, after immersing in sea cucumber steroid extract (SCSE). A completely random design with factorial was used with two variables, encompassing the varied doses (0, 2, 4 mg/L, 2 mg/L 17α-methyl testosterone as control group) and immersion times of 18 and 30 h. The result showed the dose-dependent ability of SCSE increase the male genital formation and promote the testosterone level of juvenile crayfish. In addition, the testosterone was influenced by dose and immersion duration time, with the highest level of testosterone observed in treatments of 4 mg/L SCSE with 30 h immersion was 0.248 ng/mL, while the male percentage was 77%. In conclusion, the combination of dose and immersion time significantly affected growth and testosterone levels.

• 전자공학회논문지
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• 제49권12호
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• pp.156-163
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• 2012

최근 들어 정보은닉기술에 대한 필요성이 많이 증가되고 있으며 국제치안, 군사 그리고 의료영상 등의 분야에서 그 예를 많이 볼 수 있다. 본 논문에서는 한 픽셀의 다수 MSB(MSBs: Most Significant Bits)의 Parity Bit를 이용하여 gray영상에 대해 정보를 은닉하는 방법을 제안한다. 스테가노그라피(Steganography) 분야에서 많은 연구들이 LSB 대체(Substitution), XOR연산을 채용하여 연구되어왔으며 궁극적인 목적은 낮은 복잡도와 높은 은닉용량, 동시에 화질의 저하를 최소화하는 것이다. 하지만 LSB 대체 방법은 높은 은닉용량을 가짐에도 불구하고 너무나 간단한 작업으로 인해 안전하지 못하다. 또한 XOR연산을 이용한 방법들은 픽셀 수 대비 약 75%의 은닉률을 달성하였다. 제안된 방법에서 각 픽셀의 LSB(Least Significant Bit)는 비밀메시지 1비트와 해당 픽셀의 7 MSBs의 Parity Bit와 XOR 연산된다. 제안한 방법은 대칭키 프로토콜의 개념을 스테가노그라피에 적용한 것이며 대칭키를 자기참조에 의해 생성하도록 하였다. 제시한 방법은 기존의 XOR방법들에 비해 은닉률이 25% 높으며 원본 대비 픽셀의 LSB 반전률이 약 6%정도 개선되는 효과를 보였다.

• 대한방사선기술학회지:방사선기술과학
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• 제32권1호
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• pp.95-99
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• 2009

본 연구는 뇌의 T2고속스핀에코 3.0T 자기공명영상에서 지방조직의 억제능력을 유지하면서 동시에 지방조직의 불균일성을 최소화할 수 있는 SPAIR의 적정 반전시간(TI)을 찾아보고, 지방억제기법인 STIR기법과도 비교하고자 한다. SPAIR 프로토콜의 반전시간(TI)은 SPAIR TR(420 msec)의 1/2, 1/3, 1/6, 1/12, 즉 210 msec(8명), 140 msec(26명), 70 msec(26명), 35 msec(18명)로 설정하고, STIR의 TI는 250 msec(26명)로 설정하여 뇌의 축방향 영상(104개)을 획득하였다. 출력영상의 지방조직, 근육조직, 백그라운드의 ROI($50\;mm^2$)를 설정하여 신호강도(SI)를 측정하였고, 지방과 근육조직과의 CNR을 산출하고, 지방조직에서 불균일치는 측정된 지방 신호의 평균치(mean)에 대한 표준편차(SD)로서 그 산출은 SD/mean으로 계산하였다. 측정결과는 첫째, SPAIR TI가 70 ms일 때, 지방조직의 신호강도가 TI가 140 ms 보다 낮게 측정되어 지방억제능력이 우수하였다. 둘째, SPAIR TI가 140 ms일 때, 영상의 질 측면에서 지방조직의 불균일치는 70 ms 보다 낮아서 영상의 질은 우수하게 나타났다. 따라서 SPAIR TI의 선택은 TR(420 ms)의 1/3인 140 ms와 1/6인 70 ms에서 결정되어야 하는데 지방조직의 억제능력과 지방조직의 불균일치에서 각각 통계적으로 유의한 차이(p < .001)를 보여 화질 측면에서 TI : 140 ms를 선택하는 것이 바람직하다고 생각한다. 한편, SPAIR(TI : 140 ms)와 STIR의 비교는 지방억제는 통계적으로 유의한 차이가 없으나(p < .252), 화질 측면에서 SPAIR가 STIR보다 우수한 결과를 보였고, 통계적으로 유의한 차이를 보였다(p < .01).

• The Korean Journal of Physiology and Pharmacology
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• 제8권4호
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• pp.219-225
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• 2004

The pelvic ganglia provide autonomic innervations to the various urogenital organs, such as the urinary bladder, prostate, and penis. It is well established that both sympathetic and parasympathetic synaptic transmissions in autonomic ganglia are mediated mainly by acetylcholine (ACh). Until now, however, the properties of ACh-induced currents and its receptors in pelvic ganglia have not clearly been elucidated. In the present study, biophysical characteristics and molecular nature of nicotinic acetylcholine receptors (nAChRs) were studied in sympathetic and parasympathetic major pelvic ganglion (MPG) neurons. MPG neurons isolated from male rat were enzymatically dissociated, and ionic currents were recorded by using the whole cell variant patch clamp technique. Total RNA from MPG neuron was prepared, and RT-PCR analysis was performed with specific primers for subunits of nAChRs. ACh dose-dependently elicited fast inward currents in both sympathetic and parasympathetic MPG neurons $(EC_{50};\;41.4\;{\mu}M\;and\;64.0\;{\mu}M,\;respectively)$. ACh-induced currents showed a strong inward rectification with a reversal potential near 0 mV in current-voltage relationship. Pharmacologically, mecamylamine as a selective antagonist for ${\alpha}3{\beta}4$ nAChR potently inhibited the ACh-induced currents in sympathetic and parasympathetic neurons $(IC_{50};\;0.53\;{\mu}M\;and\;0.22\;{\mu}M,\;respectively)$. Conversely, ${\alpha}-bungarotoxin$, ${\alpha}-methyllycaconitine$, and $dihydro-{\beta}-erythroidine$, which are known as potent and sensitive blockers for ${\alpha}7$ or ${\alpha}4{\beta}2$ nAChRs, below micromolar concentrations showed negligible effect. RT-PCR analysis revealed that ${\alpha}3$ and ${\beta}4$ subunits were predominantly expressed in MPG neurons. We suggest that MPG neurons have nAChRs containing ${\alpha}3$ and ${\beta}4$ subunits, and that their activation induces fast inward currents, possibly mediating the excitatory synaptic transmission in pelvic autonomic ganglia.