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Accuracy of Combined Visual Inspection with Acetic Acid and Cervical Cytology Testing as a Primary Screening Tool for Cervical Cancer: a Systematic Review and Meta-Analysis

  • Chanthavilay, Phetsavanh;Mayxay, Mayfong;Phongsavan, Keokedthong;Marsden, Donald E;White, Lisa J;Moore, Lynne;Reinharz, Daniel
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5889-5897
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    • 2015
  • Background: The performance of combined testing visual inspection with acetic acid (VIA) and cervical cytology tests might differ from one setting to another. The average estimate of the testing accuracy across studies is informative, but no meta-analysis has been carried out to assess this combined method. Objective: The objective of this study was to estimate the average sensitivity and specificity of the combined VIA and cervical cytology tests for the detection of cervical precancerous lesions. Materials and Methods: We conducted a systematic review and a meta-analysis, according to the Cochrane Handbook for Systematic Review of Diagnostic Test Accuracy. We considered two cases. In the either-positive result case, a positive result implies positivity in at least one of the tests. A negative result implies negativity in both tests. In the both-positive case, a positive result implies having both tests positive. Eligible studies were identified using Pubmed, Embase, Website of Science, CINHAL and COCRANE databases. True positive, false positive, false negative and true negative values were extracted. Estimates of sensitivity and specificity, positive and negative likelihood (LR) and diagnostic odds ratios (DOR) were pooled using a hierarchical random effect model. Hierarchical summary receiver operating characteristics (HSROC) were generated and heterogeneity was verified through covariates potentially influencing the diagnostic odds ratio. Findings: Nine studies fulfilled inclusion criteria and were included in the analysis. Pooled estimates of the sensitivities of the combined tests in either-positive and both-positive cases were 0.87 (95% CI: 0.83-0.90) and 0.38 (95% CI: 0.29-0.48), respectively. Corresponding specificities were 0.79 (95% CI: 0.63-0.89) and 0.98 (95% CI: 0.96-0.99) respectively. The DORs of the combined tests in either-positive or both-positive result cases were 27.7 (95% CI: 12.5-61.5) and 52 (95% CI: 22.1-122.2), respectively. When including only articles without partial verification bias and also a high-grade cervical intraepithelial neoplasia as a threshold of the disease, DOR of combined test in both-positive result cases remained the highest. However, DORs decreased to 12.1 (95% CI: 6.05-24.1) and 13.8 (95% CI: 7.92-23.9) in studies without partial verification bias for the combined tests in the either-positive and both-positive result cases, respectively. The screener, the place of study and the size of the population significantly influenced the DOR of combined tests in the both-positive result case in restriction analyses that considered only articles with CIN2+ as disease threshold. Conclusions: The combined test in the either-positive result case has a high sensitivity, but a low specificity. These results suggest that the combined test should be considered in developing countries as a primary screening test if facilities exist to confirm, through colposcopy and biopsy, a positive result.

A STUDY ON THE RE-QUANTIZATION METHOD FOR PREVENTING DISTORTION OF CORRELATION RESULT (상관결과의 왜곡 방지를 위한 재양자화 방법에 관한 연구)

  • Yeom, Jae-Hwan;Oh, Se-Jin;Roh, Duk-Gyoo;Oh, Chung-Sik;Jung, Jin-Seung;Chung, Dong-Kyu;Oyama, Tomoaki;Kawaguchi, Noriyuki;Kobayashi, Hideyuki;Kawakami, Kazuyuki;Onuki, Hirofumi;Ozeki, Kensuke
    • Publications of The Korean Astronomical Society
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    • v.27 no.5
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    • pp.419-429
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    • 2012
  • In this paper, we propose a new re-quantization method after FFT processing to prevent the distortion of correlation result of VCS (VLBI Correlation Subsystem). The re-quantization is used to rearrange the data bit so as to reduce the data rate processed as 16-bit of FFT result of VCS. Having done this procedure, we found that the distorted spectrum of correlation result occurred in the delay tracking experiments by the re-quantization method introduced for initial design of VCS. In order to solve this, two kinds of re-quantization method, that is, the comparison and selection-type, are proposed. The first is to re-quantize the FFT result as a valid-bit by comparing with the input data after determining the adequate threshold. The second is manually to select the valid-bit of FFT result after finding the valid-field of data according to the bit-distribution of input data. We confirmed that the second is more effective compared with the first through the experimental result, and it will be implemented without so much modification of applied method in the condition of the limited resource of FPGA. The re-quantization is, however, carried out with 4-bit in the proposed second method for FFT result, and then the distortion of correlation result is also appeared. To fix this problem, the bit for re-quantization is extended to 8-bit. The proposed 8-bit selection-type is effectively verified so that the distortion of correlation result disappeared by applying to VCS in consequence of the simulation and correlation experiments.

A Study on User Satisfaction and Importance of OPAC2.0 Services in University Libraries: Focusing on Book Search Result of A and B University Libraries (대학도서관 OPAC2.0 서비스 이용자 만족도와 중요도에 관한 연구 - A와 B대학도서관 도서검색결과를 중심으로 -)

  • Rhee, HeyYoung
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.28 no.1
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    • pp.97-119
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    • 2017
  • This research investigated user satisfaction and importance of OPAC2.0 services in university libraries for book search result. This research analyzed OPAC2.0 services in university libraries focusing on book search result, user satisfaction with and importance in services, difference in satisfaction and importance, and grade and satisfaction. As a result of the investigation and analysis, OPAC2.0 services given the most was the service of 'portal site linkage'. Generally, the satisfaction with OPAC2.0 services was 2.07 in average, 'very dissatisfactory'. The service considered to be the most important was 'service item'. The difference between satisfaction and importance showed dissatisfactory result, compared with importance in general. The grade and the general difference in satisfaction didn't appear. On the basis of the analysis result mentioned above, with the purpose of the improvement in OPAC2.0 services focusing on book search result, it is necessary to manage users continuously by publicizing libraries concerning respective services, introducing use guide, offering a variety of services, improving quality, and offering information.

The Vibration Characteristic Improvement by Mode Variation of Ring Type Ultrasonic Motor (리형 초음파모터의 모드가변에 따른 진동특성 개선)

  • 윤신용;김수석
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.18 no.2
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    • pp.115-124
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    • 2004
  • This paper suggested the vibration characteristic improvement by variation mode of ring type ultrasonic motor. Design for the piezoelectric ceramic and elastic body of stator were calculated by the finite element method(FEM) that consider the resonance frequency, vibration mode and coupling efficiency etc. Through the result of vibration analysis from 6 order mode to 8 mode, the 7 order mode was gained very an excellent results that it was the coupling efficient, minimum power loss and bending vibration value. Here over 7 order mode, was acquired that an output current for input voltage was very a large increased results. The result of vibration calculation, from thickness 0.5[mm] to 2[mm], know the fact that the vibration displacement at 0.5[mm] is an high value too. From such analysis result, this paper was manufactured the ultrasonic motor of outer diameter 50[mm], inter 22[mm] having the about 43.86[KHz] resonance frequency. We have gated that a simulation result is 42.2[KHz] and an experiment result is 43.86[KHz]. Then, a propriety of this paper was established the result almost similar to though comparison, investigation of simulation and experiment result.

A Comparative Study of Outsourcing Culinary Part of Foodservice Industry Development. (외식사업발전을 위한 조리분야 아웃소싱 전략에 관한 연구 (평가측정치 개발절차를 중심으로))

  • 김기영
    • Culinary science and hospitality research
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    • v.7 no.3
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    • pp.13-34
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    • 2001
  • The case which it contracts with the dynamic result measurement system when actual outsourcing evaluation measurement is composed and then one result standard between the service supplier and the user is set, which owns jointly the expense which is reduced from that or the benefit which is created from that is increasing In the conclusion, for outsourcing management strategy of domestic foodservice industry in order to succeed, first it is accurate and examined that for what and how outsourcing should be introduced and as a result, what kind of result can be raised from that result\ulcorner Food service industry should be outsourced if you want to make more many investment in better humane resources, food & beverage-goods-security and education to provide eating-out service out of various business in food industry. When considering the actuality of the domestic foodservice industry that time it is appropriate, it sees. The foreign-brand goods which is introduced in the country are being executing in the 1ink of part management strategy. One of the most influential factor of domestic foodservice industry's management pressure is overspent management expenses, Does the namely expenses preparation effect reach which degree\ulcorner what kind of method can most decrease these expenses\ulcorner Doing grows the success and failure of the Korean foodservice industry controls result with the fact that it will operate with a big variable sees. The background which the domestic foodservice industry should introduce inevitably the outsiurcing system is to develop continuously nation foodservice industry in the way of cost curtailment of food-material, a labor cost curtailment with efficient application and synergic effect like specialty manpower utilization. The kindred competitive enterprises gradually concentrate management resource to the point ability from the present point of view which is increasing and a strategy position they secure, to prepare a competitive power, what sees it is important national industry must prepare a new paradigm. It is important to measure the result based on sales accomplishment in operation system dimension, and it is more important to appropriately apply regard of the evaluation measurement

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The Case Analysis through Fire Simulation FDS and Evacuation Simulation Pathfinder (화재 시뮬레이션 FDS와 피난시뮬레이션 Pathfinder 사례분석)

  • Kim, Jong Yoon;Jeon, Yong Han
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.10 no.6
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    • pp.253-260
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    • 2015
  • In this study, using the FDS as the fire simulation and evacuation simulations of the Pathfinder, set the main control room of the building to the fire point fire safety assessment studies were carried out. At first the quantitative result such as distribution of visibility as time passing, distribution of temperature, distribution of CO density produced results using fire-simulation and evacuation-simulation was carried out based on the result that produced the final safety evaluation result as being calculated of evacuation time. As the risk increased with the distribution of visibility at the result of fire-simulation, evacuation-simulation was carried out using the result. Finally the result was made 127.9 sec that everyone could evacuate. The numerical results are analyzed in case of the places in the building required safe egress time for safety a as the analysis to be no more than available safe egress time was analyzed to be secured. The results of this safety evaluation represent that more smooth evacuation safety performance can be secured by linking the event of fire firefighting equipment as a result of simulating the worst conditions.

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A Comparative Study on Formulation of Three-Dimensional Elastic-Plastic Finite Deformation Analysis for Prediction Large Deflection (강부재의 대변형 예측을 위한 3차원 탄소성 유한변위해석의 정식화에 대한 비교연구)

  • Jang, Gab-Chul;Chang, Kyong-Ho
    • Journal of Korean Association for Spatial Structures
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    • v.6 no.4 s.22
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    • pp.53-61
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    • 2006
  • In th is paper, to predicting the large deformation and cyclic plastic behavior of steel members under loading, 3-Dimensional elastic-plastic FE analysis method is developed by using finite deformation theory and proposed cyclic plasticity model. finite deformation theory, described the large deformation, is formulated by using Updated-lagrangian formulation and Green's strain tensor, Jaumann's derivative of Kirchoff stress. Also, cyclic plasticity model proposed by author is applied to developed analysis method. To verification of developed analysis method, analysis result of steel plate specimen compare to the analysis result using infinitesimal deformation theory and test result. Also, load-displacement and deflection shape, analysis result of pipe-section steel column, compare to test result. The good agreement between analysis result and experiment result shown that developed 3-dimensional finite element analysis can be predict the large deformation and cyclic plastic behavior of steel members.

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A Study on the ACC Safety Evaluation Method Using Dual Cameras (듀얼카메라를 활용한 ACC 안전성 평가 방법에 관한 연구)

  • Kim, Bong-Ju;Lee, Seon-Bong
    • Journal of Auto-vehicle Safety Association
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    • v.14 no.2
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    • pp.57-69
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    • 2022
  • Recently, as interest in self-driving cars has increased worldwide, research and development on the Advanced Driver Assist System is actively underway. Among them, the purpose of Adaptive Cruise Control (ACC) is to minimize the driver's driving fatigue through the control of the vehicle's longitudinal speed and relative distance. In this study, for the research of the ACC test in the real environment, the real-road test was conducted based on domestic-road test scenario proposed in preceding study, considering ISO 15622 test method. In this case, the distance measurement method using the dual camera was verified by comparing and analyzing the result of using the dual camera and the result of using the measurement equipment. As a result of the comparison, two results could be derived. First, the relative distance after stabilizing the ACC was compared. As a result of the comparison, it was found that the minimum error rate was 0.251% in the first test of scenario 8 and the maximum error rate was 4.202% in the third test of scenario 9. Second, the result of the same time was compared. As a result of the comparison, it was found that the minimum error rate was 0.000% in the second test of scenario 10 and the maximum error rate was 9.945% in the second test of scenario 1. However, the average error rate for all scenarios was within 3%. It was determined that the representative cause of the maximum error occurred in the dual camera installed in the test vehicle. There were problems such as shaking caused by road surface vibration and air resistance during driving, changes in ambient brightness, and the process of focusing the video. Accordingly, it was determined that the result of calculating the distance to the preceding vehicle in the image where the problem occurred was incorrect. In the development stage of ADAS such as ACC, it is judged that only dual cameras can reduce the cost burden according to the above derivation of test results.

A Study of the Degree of Duty Satisfaction According to the Nurses's Characteristics (간호사의 특성이 직무만족도에 미치는 영향)

  • Lee, Hei-Jin;Kim, Sook-Nyung;Sohn, In-Soon;Han, Sang-Suk
    • Journal of Korean Academy of Nursing Administration
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    • v.6 no.1
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    • pp.5-18
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    • 2000
  • This study was conducted to analyze the degree of department satisfaction and correlation accordng to nurses's clinical characteristics. Data fors tudy were selected August, 1999. The sample coisted of 512 nurses working in K university hosptal in Seoul. The collected materials have been alyzed by percentage, average, t-test, ANOVA, arson Correlation Coefficiency using SPSS window 8.0 program. The result were as the follows ; 1. Fifty-one percent answered to be satisfactory in current department of work, and nurses who had been experienced the transfer are fifty percent, and nurse specialist is eight point two percent. 2. The order of the degree of department duty satisfaction was mutual action, professinal position, autonomy, assignment desire, relation between the doctor and nurses, wage, administration. 3. The result of the degree of department duty satisfaction according to the age has shown significant differences in administration and assignment desire, and the result of the degree of department duty satisfaction according to the education and religion has shown significant differences in administration, and the result of the degree of department duty satisfaction according to marital status has shown significant differences in wage and administration. 4. The result of the degree of department duty satisfaction according La the position has shown significant differences in administration, assignment desire and the sum of duty satisfaction, and the result of the degree of department duty satisfaction according to the nurse specialist has shown no significant differences in total areas, and the result of the degree of department duty satisfaction according to the transfer has shown significant differences in relation between the doctor and nurses, administration, autonomy and the sum of duty satisfaction. 5. The result of the degree of department duty satisfaction according to the nursing career and present assignment career has shown no significant differences in total areas, and the result of degree of department duty satisfaction according to the present assignment has shown significant differences in relation between doctor and nurses, administration, assignment desire and the sum of duty satisfaction. 6. The result of the degree of department duty satisfaction according to the request and experiences of trasfer has shown significant differences in wage, administration, assignment desire and the sum of duty satisfaction 7. The result of the degree of department duty satisfaction according to the degree of satisfaction of present assignment has shown no significant difference in professional position 8. The result of relation of nurses'a clinical characteristics and the degree of department duty satisfaction and the sum of duty satisfaction has shown no significant differences in age, present assignment career, but the result of nursing career has shown significant differences in relation between doctor and nurse, administration, autonomy, assignment desire and the sum of duty satisfaction. and the satisfaction of present assignment which was very effective on duty satisfaction was as significant correlation with wage, professinal position, relation between doctor and nurses, administration, autonomy assignment desire, mutual action and the sum of duty satisfaction. The above result show us that the degree of wage is effected on marital status, experience of transfer, degree of satisfaction of present assignment, request of transfef and the relation between doctor and nurses is effected on experience of transfer, present assignment, degree of satisfaction of present assignment and the administration is effected on age, education, marital status position, experiences of transfer, request of transfer, degree of satisfaction of present assignment and the autonomy is effected on experience of transfer, degree of satisfaction of present assignment and the assignment desire is effected on position, pre sent assignment, degree of satisfaction of present assignment, request of transfer and the mutual action is effected on present assignment. and the sum of duty satisfaction is effected on marital status, position, experience of transfer, request of transfer, present assignment, degree of satisfaction of present assignment.

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The Studies on various Causes of Cleanness Defects with in Raw Silk. (생사의 대중절 발생원인 구명에 관한 연구)

  • 최병희;마석일
    • Journal of Sericultural and Entomological Science
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    • no.12
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    • pp.21-36
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    • 1970
  • This studies have been carried out to 3nd various causes of cleanness defects on raw silk which has been increased since 1967 in Korea, so that this treatise may be a guide inform action to improve such a defect in future. The cocoon treatment for the proposed work was carried starting with in worst condition to find the critical limit of degrading through such a work. And various analysis have been also worked out using the annual silk testing data past a few years. The results obtained are as follows. 1. There was a great relationship between cleanness and neatness result. 2. Cleanness result is greatly influenced by mounting conditions and handling of cocoons, which brought 40 percent lower as cleanness result than standard ones in which caused minor defects, especially loops and split ends, so the bad mounting conditions and handling of fresh cocoons degraded raw silk from 4A grade to E. 3. The use of good water quality brought the difference of 1.04 percent in cleanness result rather than the use of bad one. 4. Well technical work brought the difference of 0.86 percent in cleanness result rather than poor technical work. 5, Satisfactory cocoon drying installation brought the difference of 1.97 percent in cleanness result rather than insufficient one. 6. Automatic reeling machine marked lower 1,55 percent in cleanness result than multi-end reeling machine. 7. The degrading of cleanness result from 1965 year silk to 1969 year silk marked 1.99 percent, which almost responds to the degrading rate from good to poor cocoon drying installed cleanness results. In view of this result, nowadays, insufficient cocoon drying installation may be main factor to be worse cleanness result of Korean raw silk. 8. The factors of cleanness defect in raw silk once supplied with cocoon into factory are water quality, technique evaluation, cocoon drying capacity and s: reeling machine. The relationship between cleanness result and above factors are as follows. cleanness result=neatness result+1.6-1.04(1-a)-1.97(1-b)-0.86(1-c)+1.55${\times}$d a: The successive we ratio of water quality (0\longrightarrowl) b: The successive ratio of satisfactory cocoon drying installation (0\longrightarrowl) c: The successive ratio of well technical work (0\longrightarrowl) d: 1 in case multi-end reeling machine o in case automatic reeling machine 9, It is not admitted that there is heavy relationship between cleanness occurrence and nonbreaking reel ability. That mal$.$ be sowed with silk reeling technique. 10. The bad mounting conditions caused the worse result on the cocoon quality as much as cleanness. 11. Besides mounting conditions, there may be another factors affecting on the low reel ability of cocoons in Korea.

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