• Title/Summary/Keyword: Response Threshold

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Estimating dose-response curves using splines: a nonparametric Bayesian knot selection method

  • Lee, Jiwon;Kim, Yongku;Kim, Young Min
    • Communications for Statistical Applications and Methods
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    • v.29 no.3
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    • pp.287-299
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    • 2022
  • In radiation epidemiology, the excess relative risk (ERR) model is used to determine the dose-response relationship. In general, the dose-response relationship for the ERR model is assumed to be linear, linear-quadratic, linear-threshold, quadratic, and so on. However, since none of these functions dominate other functions for expressing the dose-response relationship, a Bayesian semiparametric method using splines has recently been proposed. Thus, we improve the Bayesian semiparametric method for the selection of the tuning parameters for splines as the number and location of knots using a Bayesian knot selection method. Equally spaced knots cannot capture the characteristic of radiation exposed dose distribution which is highly skewed in general. Therefore, we propose a nonparametric Bayesian knot selection method based on a Dirichlet process mixture model. Inference of the spline coefficients after obtaining the number and location of knots is performed in the Bayesian framework. We apply this approach to the life span study cohort data from the radiation effects research foundation in Japan, and the results illustrate that the proposed method provides competitive curve estimates for the dose-response curve and relatively stable credible intervals for the curve.

Dynamic Response Behavior of Femtosecond Laser-Annealed Indium Zinc Oxide Thin-Film Transistors

  • Shan, Fei;Kim, Sung-Jin
    • Journal of Electrical Engineering and Technology
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    • v.12 no.6
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    • pp.2353-2358
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    • 2017
  • A femtosecond laser pre-annealing process based on indium zinc oxide (IZO) thin-film transistors (TFTs) is fabricated. We demonstrate a stable pre-annealing process to analyze surface structure change of thin films, and we maintain electrical stability and improve electrical performance. Furthermore, dynamic electrical characteristics of the IZO TFTs were investigated. Femtosecond laser pre-annealing process-based IZO TFTs exhibit a field-effect mobility of $3.75cm^2/Vs$, an $I_{on}/I_{off}$ ratio of $1.77{\times}10^5$, a threshold voltage of 1.13 V, and a subthreshold swing of 1.21 V/dec. And the IZO-based inverter shows a fast switching behavior response. From this study, IZO TFTs from using the femtosecond laser annealing technique were found to strongly affect the electrical performance and charge transport dynamics in electronic devices.

Characteristics measurement of fabricated micromirror array with vertical springs (제작된 수직 마이크로미러 어레이의 특성 측정)

  • Shin, Jong-Woo;Kim, Yong-Kweon;Park, Jin-Goo;Shin, Hyung-Jae;Moon, Jae-Ho
    • Proceedings of the KIEE Conference
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    • 1997.11a
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    • pp.618-620
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    • 1997
  • A $50{\times}50{\mu}m^2$ aluminum micromirror array is fabricated using shadow evaporation process. The fabrication process is very simple with use of shadow evaporation process, and the micromirror array has a high fill-factor. The static and dynamic characteristics such as deflection angle vs. applied voltage, step response, and frequency response are measured using a contact free optical measurement technique. The downward threshold voltage was 8 V, step response time was $13.5{\mu}s$ when 32 V step voltage applied, and a resonance observed at 11kHz. The lifetime of micromirror with anti-stiction coating was tested and micromirror operated successfully over 200 million cycles of touch-down operations.

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GLOBAL ANALYSIS FOR A DELAY-DISTRIBUTED VIRAL INFECTION MODEL WITH ANTIBODIES AND GENERAL NONLINEAR INCIDENCE RATE

  • Elaiw, A.M.;Alshamrani, N.H.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.18 no.4
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    • pp.317-335
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    • 2014
  • In this work, we investigate the global stability analysis of a viral infection model with antibody immune response. The incidence rate is given by a general function of the populations of the uninfected target cells, infected cells and free viruses. The model has been incorporated with two types of intracellular distributed time delays to describe the time required for viral contacting an uninfected cell and releasing new infectious viruses. We have established a set of conditions on the general incidence rate function and determined two threshold parameters $R_0$ (the basic infection reproduction number) and $R_1$ (the antibody immune response activation number) which are sufficient to determine the global dynamics of the model. The global asymptotic stability of the equilibria of the model has been proven by using Lyapunov theory and applying LaSalle's invariance principle.

GLOBAL STABILITY OF VIRUS DYNAMICS MODEL WITH IMMUNE RESPONSE, CELLULAR INFECTION AND HOLLING TYPE-II

  • ELAIW, A.M.;GHALEB, SH.A.
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.23 no.1
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    • pp.39-63
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    • 2019
  • In this paper, we study the effect of Cytotoxic T Lymphocyte (CTL) and antibody immune responses on the virus dynamics with both virus-to-cell and cell-to-cell transmissions. The infection rate is given by Holling type-II. We first show that the model is biologically acceptable by showing that the solutions of the model are nonnegative and bounded. We find the equilibria of the model and investigate their global stability analysis. We derive five threshold parameters which fully determine the existence and stability of the five equilibria of the model. The global stability of all equilibria of the model is proven using Lyapunov method and applying LaSalle's invariance principle. To support our theoretical results we have performed some numerical simulations for the model. The results show the CTL and antibody immune response can control the disease progression.

Study on of polarity effect on alignment film in transcription-aligned TN-LCD (전사배향 TN-LCD 에서의 배향막의 극성효과에 관한 연구)

  • Kim, Jin-Ho;Seo, Dae-Shik
    • Proceedings of the KIEE Conference
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    • 1999.07d
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    • pp.1812-1814
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    • 1999
  • The effects of polarity of the polymer on transcription-aligned twisted nematic (TN)-liquid crystal display (LCD) on various the polyimide (PI) surfaces were investigated. The monodomain alignment of nematic (N)LC is obtained in cells fabricated by transcription alignment method on PI surface with medium polarity. The LC alignment using transcription alignment method is attributed to polarity of the polymer. The threshold voltage of transcription-aligned TN-LCD decreases with increasing the polarity of the polymer on three kinds of the PI surfaces. The threshold voltage of transcription-aligned TN-LCD on PI surface with high polarity is almost the same compared to rubbing-aligned TN-LCD. The response time of transcription-aligned TN-LCD decreases with the increasing the polarity of the polymer on all PI surfaces. The decay time of transcription-aligned TN-LCD is slow compared with the rubbing-aligned TN-LCD.

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New Dynamic Adaptive Threshold Destage Algorithms for Cached RAID 5 (RAID 5의 성능향상을 위한 쓰기 캐쉬의 동적 적응 반출기법)

  • Yie, Hyeok;Choi, Sang-Bang
    • Proceedings of the IEEK Conference
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    • 2000.06c
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    • pp.47-50
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    • 2000
  • In this paper, we propose a new destage algorithms, called the Dynamic Adaptive Threshold which determines turn-on and turn-off thresholds dynamically depending on the current write cache occupancy level and the differential rate of the host write requests. For performance evaluation, the proposed algorithm is compared with the wellknown High-Low Water Mark (HLWM) algorithm. Performance tests are fulfilled with our cached RAID 5 simulator. The simulation results show that the proposed algorithm outperforms the HLWM algorithm in terms of response time of host reads and write cache hit ratio under various workloads.

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M/G/1 복수 휴가 모델을 이용한 IEEE 802.16e 무선 MAN 수면모드 작동에 대한 성능분석

  • Jeong, Seong-Hwan;Hong, Jeong-Wan;Jang, U-Jin;Lee, Chang-Hun
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2007.11a
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    • pp.195-203
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    • 2007
  • In this paper, an analytic model of sleep model operation in the IEEE 802.16e is investigated. A mobile subscribe. station (MSS) goes to sleep mode after negotiations with the base station (BS) and wakes up periodically for a short interval to check whether there is downlink traffic to it. If the arrival of traffic is notified, an MSS returns to wake mode. Otherwise, it again enters increased sleep interval which is double as the previous one. In order to consider the situation more practically, we propose the sleep mode starting threshold, during which MSS should await packets before it enters the sleep mode. By modifying the M/G/1 with multiple vacations model, energy consumption ratio(ECR) and average packet response time are calculated. Our analytic model provides potential guidance in determining the optimal parameters values such as sleep mode starting threshold, minimal sleep and maximal sleep window.

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Development of Ambulatory Speech Audiometric System (휴대용 어음청력검사 시스템 구현)

  • Shin, Seung-Won;Kim, Kyeong-Seop;Lee, Sang-Min;Im, Won-Jin;Lee, Jeong-Whan;Kim, Dong-Jun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.58 no.3
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    • pp.645-654
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    • 2009
  • In this study, we present an efficient ambulatory speech audiometric system to detect one's hearing problems at an earlier stage as possible without his or her visit to the audiometric testing facility such in a hospital or a clinic. To estimate a person's hearing threshold level in terms of speech sound response in his or her local environment, a digital assistant(PDA) device is used to generate the speech sound with implementing audiometric Graphic User Interface(GUI) system. Furthermore, a supra-aural earphone is used to measure a subject's hearing threshold level in terms of speech sound by the compensating the transducer's gain by adopting speech sound calibration system.

Effects of Polarity of the Orientation Film for Electro-optical Characteristics on a-TN-LCD (배향막의 극성이 a-TN-LCD의 전기광학특성에 미치는 효과)

  • 서대식;이창훈;이보호
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1997.04a
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    • pp.27-30
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    • 1997
  • We investigated the electro-optical characteristics of amorphous (a) - twisted nematic (TN) - liquid crystal display (LCD) on polyimide (Pl) films with different polarity. It was found that the threshold voltage of a-TN-LCD is decreased with increasing the polarity of the Pl film. We considered that the threshold voltage in a-TN-LCD is affected to the surface anchoring strength with polarity of the Pl films. Also, we observed the response time of a-TN-LCD on medium polarity of the Pl film is fast compared to high polarity of the Pl film. Finally, we obtained that the viewing angle of a-TN-LCD are almost same on different polarity of the PI films.

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