• Title/Summary/Keyword: Response

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Probabilistic study of the influence of ground motion variables on response spectra

  • Yazdani, Azad;Takada, Tsuyoshi
    • Structural Engineering and Mechanics
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    • v.39 no.6
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    • pp.877-893
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    • 2011
  • Response spectra of earthquake ground motions are important in the earthquake-resistant design and reliability analysis of structures. The formulation of the response spectrum in the frequency domain efficiently computes and evaluates the stochastic response spectrum. The frequency information of the excitation can be described using different functional forms. The shapes of the calculated response spectra of the excitation show strong magnitude and site dependency, but weak distance dependency. In this paper, to compare the effect of the earthquake ground motion variables, the contribution of these sources of variability to the response spectrum's uncertainty is calculated by using a stochastic analysis. The analytical results show that earthquake source factors and soil condition variables are the main sources of uncertainty in the response spectra, while path variables, such as distance, anelastic attenuation and upper crust attenuation, have relatively little effect. The presented formulation of dynamic structural response in frequency domain based only on the frequency information of the excitation can provide an important basis for the structural analysis in some location that lacks strong motion records.

Response Evaluation of Chemotherapy for Lung Cancer

  • Hwang, Ki-Eun;Kim, Hak-Ryul
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.2
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    • pp.136-142
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    • 2017
  • Assessing response to therapy allows for prospective end point evaluation in clinical trials and serves as a guide to clinicians for making decisions. Recent prospective and randomized trials suggest the development of imaging techniques and introduction of new anti-cancer drugs. However, the revision of methods, or proposal of new methods to evaluate chemotherapeutic response, is not enough. This paper discusses the characteristics of the Response Evaluation Criteria In Solid Tumor (RECIST) version 1.1 suggested in 2009 and used widely by experts. It also contains information about possible dilemmas arising from the application of response assessment by the latest version of the response evaluation method, or recently introduced chemotherapeutic agents. Further data reveals the problems and limitations caused by applying the existing RECIST criteria to anti-cancer immune therapy, and the application of a new technique, immune related response criteria, for the response assessment of immune therapy. Lastly, the paper includes a newly developing response evaluation method and suggests its developmental direction.

A Study of Discriminant Analysis about Korean Quick Response System Adoption (국내(國內) 신속대응(迅速對應)시스템 도입업체(導入業體)의 판별분석(判別分析) 연구(硏究))

  • Ko, Eun-Ju
    • Journal of Fashion Business
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    • v.4 no.3
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    • pp.103-114
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    • 2000
  • The purpose of this study was to test the discriminant analysis model of Quick Response system and to examine the detailed relationship between each discriminant factor and Quick Response adoption. In this discriminant analysis model of Quick Response system, firm size, strategic type, product category, fashion trend, selling time and the Quick Response benefits were included as discriminant factors. Onehundred and two subjects were randomly selected for the survey study and discriminant analysis, descriptive analysis, t-test, and x square test were used for the data analysis. The results of this study were: 1. Wilks Lambda and F value support the discriminant analysis model that, taken together firm size, strategic type, product category, fashion trend, selling time and the Quick Response benefits significantly help to explain Quick Response adoption. 2. The importance of discriminant ability was, in order, firm size, the Quick Response benefits, women's wear, fashion trend, analyzer, selling time, reactor, defender and men's wear. 3. The discriminant function had the high hit ratio, so this can be well used for the classification of Quick Response adoption/nonadoption.

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Stochastic response spectra for an actively-controlled structure

  • Mochio, Takashi
    • Structural Engineering and Mechanics
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    • v.32 no.1
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    • pp.179-191
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    • 2009
  • A stochastic response spectrum method is proposed for simple evaluation of the structural response of an actively controlled aseismic structure. The response spectrum is constructed assuming a linear structure with an active mass damper (AMD) system, and an earthquake wave model given by the product of a non-stationary envelope function and a stationary Gaussian random process with Kanai-Tajimi power spectral density. The control design is executed using a linear quadratic Gaussian control strategy for an enlarged state space system, and the response amplification factor is given by the combination of the obtained statistical response values and extreme value theory. The response spectrum thus produced can be used for simple dynamical analyses. The response factors obtained by this method for a multi-degree-of-freedom structure are shown to be comparable with those determined by numerical simulations, demonstrating the validity and utility of the proposed technique as a simple design tool. This method is expected to be useful for engineers in the initial design stage for structures with active aseismic control.

Aircraft Wing Spar Cross-section Area Optimization with Response Surface Method (반응면 기법을 이용한 항공기 날개 스파 단면적의 최적화 연구)

  • Park, Chan-Woo
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.4
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    • pp.109-116
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    • 2002
  • The solution of the aircraft wing spar cross-section area optimization problem is obtained by the response surface method. The object function of the problem is wing total weight, design variables are spar cross-section areas, constraints are the conditions that the stresses at the each spar is less than the allowable stress. D-Optimal condition is utilized to obtain the experimental points to construct the response surfaces. D-Optimal experimental points are obtained by the commercial software "Deign-Expert". Response values for the object function and constraints for each experimental point are calculated by the NASTRAN. Response surfaces for object function and constraints are approximated from the response values by the least square method. The optimization solution is obtained by the DOT for the response surfaces of object function and constraints. The optimization results obtained from the response surface are compared with the results obtained by the NASTRAN SOL200.

A STUDY ON THE FACTORS INFLUENCING PRESCHOOL CHILDREN'S RESPONSE AT DENTAL VISIT (치과치료시 미취학 아동의 행동반응에 영향을 주는 요인에 관한 연구)

  • Kim, Hyung-Doo;Cha, Moon-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.11 no.1
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    • pp.103-112
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    • 1984
  • Eighty children, aged from 2 years 8 months to 5 years 1 month old, were examined to study the relationship between the preschool children's response at dental visit and the influencing factors. The results were as follows: 1, There was no significant relationship between the sexes and the children's response. 2. Children who experienced the painful dental treatment demonstrated significantly more negative dental response. 3. Children who stowed negative dental behavior at last dental visit demonstrated significantly more negative dental response. 4. Children of mothers with high anxiety scores demonstrated significantly more negative dental response. 5, Children who were unpleasant at hospitaization demonstrated significantly more negative dental response. 6. Children who thought they had dental problems demonstrated significantly the most negative dental response. 7. Children who abhorred the medical treatment demonstrated significantly more negative dental response.

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The effects of job characteristics and psychological stress response on accidents, and the mediating effect of psychological stress response (직무특성과 심리적 스트레스 반응이 사고빈도에 미치는 효과 및 심리적 반응의 매개효과)

  • Kim, Wan-Il;Ahn, Kwan-Young
    • Journal of the Korea Safety Management & Science
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    • v.15 no.1
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    • pp.41-49
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    • 2013
  • This paper reviewed the relationship among job characteristics, psychological stress response, and accidents, and the mediating effect of psychological stress response between job characteristics and accidents. Based on the responses from 176 employees, the results of multiple regression analysis appeared as follow; 1) autonomy, importance and feedback effect negatively on psychological stress response. 2) psychological stress response effects positively on accident frequency. 3) psychological stress response mediates fully between autonomy and accident. 4) psychological stress response mediates partly between feedback and accident.

Thermosensing of Thermotactic Mutants, Dictyostelium discoideum Amoebae in Vegetative Stage

  • Hong, Choo-Bong
    • Journal of Plant Biology
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    • v.26 no.3
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    • pp.131-139
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    • 1983
  • Temperature response of amoebae of thermotactic mutants have been investigated. Amoebae of the mutant strain HO 428 showed positive thermotaxs which is strong at lower temperaturs and drops sharply above the growth temperature of amoebae. The temperature response of HO 428 amoebae was not affected by the length of amoebae on the grdients. HO 596 amoebae seemed to have both positive and negative thermotactic responses shortly after food depletion. Longer exposure of these amoebae on the thermal gradients induced a stronger negative response at lower temperatures and an apparent positive response at higher temperatures. A similar changes could be observed in HO 1445 amoebae. Based on the steady positive thermotactic response by HO 428 amoebae and the mode of change in termperature response at higher temperatures, 24$^{\circ}C$ and $25^{\circ}C$, by HO 596 amoebae, a model for the temperature response of vegetative Dictyostelium discoideum amoebae, strain HL 50, has been proposed. The main features of the model are: a positive response at the thermal gradients with midpoint temperatures lower than the growth temperatures of amoebae and a negative response above it.

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Application of Response Spectrum Analysis Method for the Estimation of the Vertical Vibration in Structures (구조물의 연직진동해석을 위한 응답 스펙트럼 해석법의 활용)

  • 이동근
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 1998.10a
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    • pp.12-19
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    • 1998
  • Response spectrum analysis method is widely used for seismic analysis of building structure. Analysis of structural vibration for equipment, machine and moving loads are executed by time history analysis. This method is very complex, difficult and tedious. In this study, maximum response of structure for this case are simply and fast. calculated by mode shape and response spectrum for excitation. At first, Response spectrum and time history analysis for some earthquake is carried and investigate the error of maximum displacement response for R. S. A. Secondly, The process for response spectrum analysis in excitation are calculated, and maximum model response are combined by CQC (Complete Quadratic Combination) methods. Finally, Combining maximum displacement response is compared with one of time history analysis.

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A Measure for Evaluating the Effect of Blocking in Response Surface Designs Using Cuboidal Regions (입방형 영역을 사용한 반응표면계획에서 블록효과를 평가하기 위한 측도)

  • 박상현;장대흥
    • Journal of Korean Society for Quality Management
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    • v.27 no.1
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    • pp.59-79
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    • 1999
  • The fitting of a response surface model and the subsequent exploration of the response surface are usually based on the assumption that the experimental runs are carried out under homogeneous conditions. This, however, may be quite often difficult to achieve in many experiments. To control such an extraneous source of variation, the response surface design should be arranged in several blocks within which homogeneity of conditions can be maintained. In this case, when fitting a response surface model, the least squares estimates of the model's parameters and the prediction variance will generally depend on how the response surface design is blocked. That is, the choice of a blocking arrangement for a response surface design can have a considerable effect on estimating the mean response and on the size of the prediction variance. In this paper, we propose a measure for evaluating the effect of blocking of response surface designs using cuboidal regions.

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