• 대한의용생체공학회:의공학회지
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• 제28권5호
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• pp.676-683
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• 2007

A non-invasive respiratory gated radiotherapy system like those based on external anatomic motion gives better comfortableness to patients than invasive system on treatment. However, higher correlation between the external and internal anatomic motion is required to increase the effectiveness of non-invasive respiratory gated radiotherapy. Both of invasive and non-invasive methods need to track the internal anatomy with the higher precision and rapid response. Especially, the non-invasive method has more difficulty to track the target position successively because of using only image processing. So we developed the system to track the motion for a non-invasive respiratory gated system to accurately find the dynamic position of internal structures such as the diaphragm and tumor. The respiratory organ motion tracking apparatus consists of an image capture board, a fluoroscopy system and a processing computer. After the image board grabs the motion of internal anatomy through the fluoroscopy system, the computer acquires the organ motion tracking data by image processing without any additional physical markers. The patients breathe freely without any forced breath control and coaching, when this experiment was performed. The developed pattern-recognition software could extract the target motion signal in real-time from the acquired fluoroscopic images. The range of mean deviations between the real and acquired target positions was measured for some sample structures in an anatomical model phantom. The mean and max deviation between the real and acquired positions were less than 1mm and 2mm respectively with the standardized movement using a moving stage and an anatomical model phantom. Under the real human body, the mean and maximum distance of the peak to trough was measured 23.5mm and 55.1mm respectively for 13 patients' diaphragm motion. The acquired respiration profile showed that human expiration period was longer than the inspiration period. The above results could be applied to respiratory-gated radiotherapy.

• Investigative Magnetic Resonance Imaging
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• 제22권1호
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• pp.71-77
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• 2018

Purpose: To develop a two-dimensional (2D) image-based respiratory motion correction technique for free-breathing coronary magnetic resonance angiography (MRA). Materials and Methods: The proposed respiratory navigator obtained aliased a 2D sagittal image from under-sampled k-space data and utilized motion correlation between the aliased images. The proposed navigator was incorporated into the conventional coronary MRA sequence including the diaphragm navigator and tested in three healthy subjects. Results: The delineation of major coronary arteries was significantly improved using the proposed 2D motion correction (S/I and A/P) compared to one-dimensional (S/I) correction using the conventional diaphragm navigator. Conclusion: The 2D image-based respiratory navigator was proposed for free-breathing coronary angiography and showed the potential for improving respiratory motion correction compared to the conventional 1D correction.

• 대한물리의학회지
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• 제16권3호
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• pp.29-36
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• 2021

PURPOSE: The respiratory function and range of joint mobility deteriorate due to aging, respectively, and the respiratory function may be related to the range of joint mobility. To the best of the authors' knowledge, there has been little research on how the deterioration of the range of joint mobility caused by aging is related directly to the respiratory function. This study investigated the relationship between the respiratory function and the range of joint motion in the cervical and lumbar regions of older adults. METHODS: Thirty-two older adults participated in the study. The forced vital capacity (peak expiratory flow: PEF and forced expiratory volume in 1 second: FEV1) and the range of cervical joint motion were assessed in all subjects. The results were analyzed using the Pearson's correlation coefficient. RESULTS: The respiratory function moderately correlated with age. A moderate correlation was observed between FEV1 and right cervical lateral flexion. PEF was moderately correlated with the lumbar lateral flexion. In addition, FEV1 correlated strongly with lumbar lateral flexion. CONCLUSION: The respiratory function was correlated with the cervical and lumbar lateral flexion. Therefore, rehabilitation of the respiratory function should involve improving the limited range of motion of the joints, and a stretching program is needed for older adults.

• Physical Therapy Rehabilitation Science
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• 제10권3호
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• pp.328-336
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• 2021

Objective: The purpose of this study was to investigate the effect of cervical range of motion training on the change in respiratory function growth rate at the group and individual level in stroke patients and stroke patients with tracheostomy tube. Design: A Multilevel Growth Model Methods: 8 general stroke patients and 6 stroke patients who had a tracheostomy tube inserted were subjected to cervical range of motion training 3 times a week for 4 weeks. Force vital capacity (FVC), Forced expiratory volume in the first second (FEV1), Forced expiration ratio (FEV1/FVC) and Manual assist peak cough flow (MPCF) were measured. Data were analyzed using descriptive statistics and multilevel analysis with HLM 8.0. Results: A significant difference was found in the respiratory function analysis growth rate of the entire group (p<0.05), and two groups were added to the research model. The linear growth rate of respiratory function in patients with general stroke increased with the exception of FEV1/FVC (p<0.05). Stroke patients with tracheostomy tube showed a decreasing pattern except for FVC. In particular, MPCF showed a significantly decreased result (p<0.05). Conclusions: This study found that the maintenance of improved respiratory function in stroke patients with tracheostomy tube decreased over time. However, cervical range of motion training is still a useful method for respiratory function in general stroke patients and stroke patients with tracheostomy tube.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권7호
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• pp.2191-2208
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• 2022

Motion blur in PET (Positron emission tomography) images induced by respiratory motion will reduce the quality of imaging. Although exiting methods have positive performance for respiratory motion correction in medical practice, there are still many aspects that can be improved. In this paper, an improved 3D unsupervised framework, Res-Voxel based on U-Net network was proposed for the motion correction. The Res-Voxel with multiple residual structure may improve the ability of predicting deformation field, and use a smaller convolution kernel to reduce the parameters of the model and decrease the amount of computation required. The proposed is tested on the simulated PET imaging data and the clinical data. Experimental results demonstrate that the proposed achieved Dice indices 93.81%, 81.75% and 75.10% on the simulated geometric phantom data, voxel phantom data and the clinical data respectively. It is demonstrated that the proposed method can improve the registration and correction performance of PET image.

• 전자공학회논문지
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• 제51권12호
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• pp.111-122
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• 2014

방사선요법이 암의 치료에 널리 사용되는 방법 중의 하나가 되면서 호흡에 의한 환자 움직임의 정확한 추적은 치료 계획이나 조사량 계산에 있어 매우 중요한 요소가 되고 있다. 호흡에 의한 움직임의 부정확한 추적은 일반 조직의 오류나 높은 준위의 방사선에 노출되는 건강한 조직의 범위를 확대시키는 심각한 논란을 야기할 수 있다. 다양한 호흡 예측에 대한 기술이 연구가 되었지만, 대부분의 기술들은 특정 전자장치나 고가의 부품을 필요로 하였다. 본 논문에서는 기존의 기술에 비하여 저가이고 사용이 간편한 대안으로서 스테레오 비전 기술을 이용하여 시각 코드 타겟을 추출하고 복호화하여 새로운 3차원 호흡 추적 방법을 제안한다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 Ⅳ
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• pp.1863-1866
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• 2003

In this study, respiratory motion is modeled by a 2-Dimensional linear expanding-shrinking movement. According to the introduced model, respiratory motion imposes phase error, non-uniform sampling and amplitude modulation distortions on the acquired MRI data. When the motion parameters are known or can be estimated, a reconstruction algorithm based on superposition method was used to removed the MRI artifact. For the purpose of estimating unknown motion parameters, we applied the spectrum shift method to find the respiratory fluctuation function, the x directional expansion coefficient and its center, and also we used the minimum energy method to find the y directional expansion coefficient and its center. The effectiveness of this presented method is shown by Computer simulations.

• 융합신호처리학회 학술대회논문집
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• 한국신호처리시스템학회 2003년도 하계학술대회 논문집
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• pp.58-61
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• 2003

In this study, a planar respiratory motion is modeled by a 2-D linear expanding-shrinking movement. According to the introduced model, respiratory motion imposes phase error, non-uniform sampling and amplitude modulation distortions on the acquired MRI data. When the motion parameters are known or can be estimated, a construction algorithm based on superposition method was used to remove the MRI artifact. For the purpose of estimating unknown motion parameters, we used the spectrum shift method to find the respiratory fluctuation function, the x directional expansion coefficient and its center, and we also used the minimum energy method to find the y directional expansion coefficient and its center. Finally the effectiveness of this presented method is shown by computer simulations.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2005년도 제30회 춘계학술대회
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• pp.59-63
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• 2005

호흡 움직임은 종양에 대한 방사선치료의 부정확한 방사선조사가 유도되도록 복부 및 흉부에서 움직임을 야기한다. 그러므로 치료시 이러한 움직임에 대한 정확한 계산은 정상조직에는 저 선량을 조사되도록 CTV의 마진을 줄일 수 있고 방사선치료에 발생되는 부작용을 줄일 수 있다. Intrafraction motion을 고려하는 기술로는 호흡 멈춤, 호흡동조, 4차원 또는 종양추적 기술이 있다. 호흡동조 방법은 환자의 호흡 신호가 호흡주기의 일정한 범위에 위치할 때 주기적으로 빔을 조사하고 그 범위를 벗어날 때는 빔을 조사하지 않는 방법이다. 이러한 기술은 내부장기 움직임과 상관관계가 있는 호흡 움직임 신호의 획득이 요구된다. 호흡동조 방사선치료를 위한 예비연구로 본 연구자들은 호흡 움직임 신호 측정을 수행하였다. 환자의 호흡 움직임 신호 측정을 위해서, 호흡측정시스템을 3 가지 센서, 4 채널 데이터 획득 시스템, 신호처리용 컴퓨터로 구성하였다. 2명의 환자를 대상으로 본 연구자들은 호흡측정시스템을 가지고 호흡주기 및 파형을 평가하였다. 그 결과 호흡주기는 시간의 함수에 따라 일반적으로 정확한 대칭 형태는 아니지만 주기적인 형태로 측정되었다. 호흡측정 시스템은 기대했던 만큼 환자의 호흡을 잘 추적하였으며 실험에 적용하기 위해 쉽게 컨트롤 할 수 있었다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
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• pp.61-61
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• 2006