• Asian-Australasian Journal of Animal Sciences
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• v.29 no.11
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• pp.1555-1561
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• 2016

Shank skin color of Korean native chicken (KNC) shows large color variations. It varies from white, yellow, green, bluish or grey to black, whilst in the majority of European breeds the shanks are typically yellow-colored. Three shank skin color-related traits (i.e., lightness [$L^*$], redness [$a^*$], and yellowness [$b^*$]) were measured by a spectrophotometer in 585 progeny from 68 nuclear families in the KNC resource population. We performed genome scan linkage analysis to identify loci that affect quantitatively measured shank skin color traits in KNC. All these birds were genotyped with 167 DNA markers located throughout the 26 autosomes. The SOLAR program was used to conduct multipoint variance-component quantitative trait locus (QTL) analyses. We detected a major QTL that affects $b^*$ value (logarithm of odds [LOD] = 47.5, $p=1.60{\times}10^{-49}$) on GGA24 (GGA for Gallus gallus). At the same location, we also detected a QTL that influences $a^*$ value (LOD = 14.2, $p=6.14{\times}10^{-16}$). Additionally, beta-carotene dioxygenase 2 (BCDO2), the obvious positional candidate gene under the linkage peaks on GGA24, was investigated by the two association tests: i.e., measured genotype association (MGA) and quantitative transmission disequilibrium test (QTDT). Significant associations were detected between BCDO2 g.9367 A>C and $a^*$ ($P_{MGA}=1.69{\times}10^{-28}$; $P_{QTDT}=2.40{\times}10^{-25}$). The strongest associations were between BCDO2 g.9367 A>C and $b^*$ ($P_{MGA}=3.56{\times}10^{-66}$; $P_{QTDT}=1.68{\times}10^{-65}$). However, linkage analyses conditional on the single nucleotide polymorphism indicated that other functional variants should exist. Taken together, we demonstrate for the first time the linkage and association between the BCDO2 locus on GGA24 and quantitatively measured shank skin color traits in KNC.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.6
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• pp.779-783
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• 2006

The adiponectin gene is known to be involved in the regulation of energy homeostasis involving food intake, carbohydrate and lipid metabolism. Human adiponectin gene polymorphisms have been recently reported to be associated with obesity, insulin sensitivity and the risk of type 2 diabetes. The present study was carried out to investigate the porcine adiponectin gene as a candidate gene for fat deposition and carcass traits. A mutation of A178G of the porcine adiponectin gene that resulted in substitution of the amino acid Isoleucine to Valine was identified. AcyI PCR-RFLP was used to detect the polymorphism of the genotypes in five different pig populations (Large White, Landrace, Duroc, Chinese breeds Meishan and Qingping). The A allele frequency was significantly higher among subjects from Chinsese lard type breeds, while the G allele was the only one present in those from Western lean type breeds. To determine if there was an association of the polymorphism with phenotypic variation, the mutation was tested in 267 pigs of the "Large $White{\times}Meishan$" F2 resource population. The results of association analyses showed significant associations of the genotypes with fat deposition and carcass traits. Allele G was significantly associated with increase in loin eye height, loin eye area and lean meat percentage and bone percentage, and decrease in fat mean percentage, ratio of lean to fat, shoulder fat thickness, 6-7 rib fat thickness, thorax-waist fat thickness and buttock fat thickness. The substitution of A178G (Ile60Val) happened to be located at amino acid 60 in the collagenous domain of porcine adiponectin which might affect the association into higher-order structures, and accordingly affect the posttranslational modifications and optimal biological activity of the multimeric forms. The identified functional polymorphism provides new evidence of adiponectin as an important candidate gene affecting fat deposition and carcass traits in pigs.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1895-1899
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• 2012

Background and Aims: Liver cancer is a major health problem in low-resource countries. Approximately 55% of all liver cancer occurs in China. Hebei Province is one of the important covering nearly 6% of the population of China. The aim of this paper was to explore liver cancer mortality trends during past 30 years, and provide basic information on prevention strategies. Methods: Hebei was covered covered all the three national surveys during 1973-1975, 1990-1992, and 2004-2005 and one provincial survey during 1984-1986. Subjects included all cases dying from liver cancer in Hebei Province. Liver cancer mortality trend and geographic differences across cities and counties were analyzed. Results: There were 82,878 deaths in Hebei Province during 2004-2005 with an average mortality rate was 600.9/10,000, and an age-adjusted rate of 552.3/10,000. Those dying of cancer were 18,424 cases, accounting for 22.2% of all deaths, second only to cerebrovascular disease as a cause of death. Cancer mortality was 133.6/100,000 (age-adjusted rate was 119.2/100,000). Liver cancer ranked fourth in this survey with a mortality rate of 21.0/100,000, 28.4/100,000 in males and 13.35/10,000 in females, accounting for 15.7%, 17.1% and 13.4% of the total number of cancer deaths and in males and females, respectively. The sex ratio was 2.13. Since the 1970s, liver cancer deaths of Hebei province have been increasing slightly. The crude mortality rates in the four surveys were 11.3, 16.0, 17.4, 21.0 per 100,000, respectively, with age-adjusted rates fluctuating during the past 30 years, but the trend also being upwards. There is a tendency for the mortality rates to be higher in coastal than mountain areas, and is relative lower in the plain area, with crude mortality rates of 25.3, 22.1, and 19.1 per 100,000, respectively. There were no notable differences in cride data between urban and rural, but the age-adjusted mortality rate in rural was much higher. Conclusion: Our study indicated that the mortality of liver cancer in Hebei Province is lower than the national average level. There is a slightly increase trend, especially in some counties. Liver cancer is a major health problem and it is necessary to further promote prevention strategies in Hebei province.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.861-866
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• 2012

This study assessed the effectiveness of three intervention strategies to improve the participation rate of gastric cancer screening among people who had never undergone such screening, and those who had been screened for the disease, but not recently. It was conducted in the Ilsandong-gu District of Goyang City, Korea. The population for the current study was restricted to male residents, aged 40-65 years, who received an invitation letter to undergo gastric cancer screening from the National Health Insurance (NHI) Corporation at the beginning of 2010. The subjects were divided into two categories according to their screening history: never-screened, and ever-screened. A total of 2,065 men were eligible: 803 never-screened and 1,262 ever-screened. In each screening category they were randomly assigned to one of three intervention groups: 1) tailored telephone counseling; 2) tailored postcard reminder after tailored telephone counseling;and 3) tailored telephone counseling after tailored postcard reminder. At 3 months post-intervention, never-screened men with any intervention were more likely to undergo gastric cancer screening (OR=2.75, 95% CI: 1.22-6.18) compared to those in the reference group (no intervention). However, there was no statistically significant intervention effect in ever-screened men (OR=1.21, 95% CI: 0.65-2.27). Examination of the intervention effects by intervention group among never-screened men showed that those in the postcard reminder after telephone counseling group to be statistically significantly more likely to undergo gastric cancer screening (OR=4.49, 95% CI: 1.79-11.29) than the reference group (no intervention). Our results highlight that use of tailored postcard reminders after tailored telephone counseling is an effective method to increase participation in gastric cancer screening among men who had never been screened.

• Korean Journal of Ecology and Environment
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• v.38 no.2 s.112
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• pp.249-260
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• 2005

Dynamics of phytoplankton community were monthly examined at two sites in Lake Juam from January to December 2003. One site is located near the Dam, an intake tower, where obtain a drinking water resource, the other site is located in the shallow region, Mundeok-bridge, the upstream or effluent part of lake. During the study, there made little the differences in physicochemical factors between two sites, but numbers of species and standing crops of phytoplankton differ remarkably. Totally, 41% of green algae and 35.8% of diatoms were comprised of total phytoplankton species, while 46.3% of dinoflagellates and 27.6% of cyanobacteria contributed in total standing crops of Phytoplankton community. Cyanobacterium Microcystis aeruginora and diatom Fragilaria crotonensis dominated the Dam site during a warm season, while dinoflagellates Peridinium bipes and Asterionella formosa were at the shallow region during a cold season, respectively. According to the CCA analysis, dissolved oxygen, chemical oxygen demand and total phosphate strongly affected the growth of P. bipes with low water temperature. In addition, the increment of total nitrogen and water temperature affected biomass of a cyanobacterium M. aeruginosa. Collectively, it may suggest that the majority of annual primary production of Lake Juam is covered by two dominant species Peridinium bipes in cold season and Microcystis aeruginosa in warm season.

• Korean Journal of Poultry Science
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• v.42 no.4
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• pp.315-325
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• 2015

Recently, livestock breeding is more focused on the meat quality rather than meat quantity, mainly due to the improvement of consumers' income. Among the meat quality traits, meat color is one of very important traits because meat color is the first selection criterion from the consumers in the market. Most of the economically important traits have continuous variations and these are called quantitative traits. the genomic locations affecting these traits are called quantitative trait locus (QTL), which is mostly controlled by many genes having small effects. In this study, the recent QTL and candidate gene studies were reviewed in order to meet the consumers' demand for the future market. In the chicken QTL database, three traits are related with meat colors, namely breast color (Bco), meat color (Mco), drip loss (DL) and pH. The identified number of QTLs is 33 from 13 chromosomal regions. In these QTL regions, 14 candidate genes were identified; Eight for meat color (APP, BCMO1, COL1A2, FTO, KPNA2, PSMD12, G0S2, FTSJ3), two for drip loss (AGRP, FTO) and four for pH (GALNT1, PCDH19, DIAPH1, SPP2). These QTLs and candidate genes need to be confirmed and fine mapping is ultimately needed for identification of causative variations. The recently developed chicken resource population using Korean native chicken can be used for the improvement of meat quality traits, which increase the value that needed in the chicken industry.

• Journal of Environmental Impact Assessment
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• v.27 no.3
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• pp.267-278
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• 2018

With climate change and population growth, there are significant increases in water scarcity. There have been water security assessments to abate the gap between water demand and availability to support water resource management. However, most of the assessments are focusing on the water that flows through either on or below the land surface, failing to consider water that infiltrates and can be used by vegetation. This study presents water scarcity assessment accounting for Blue and Green water concept, and applied the method to Boryung region. Monthly streamflow, evapotranspiration, and soil moisture were estimated by SWAT modeling, and each of them was used to analyze Blue and Green water scarcity. Blue and Green water scarcity had different aspect, and the result indicated the time when water scarcity is more likely to happen. The water scarcity assessment framework presented in this paper provides novel assessment method integrating hydrologic and ecosystem aspects, thereby improving the understanding of how water resources should be managed.

• Journal of The Korean Association For Science Education
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• v.35 no.5
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• pp.885-893
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• 2015

In this study, we compared the use of information and communications technology (ICT) by middle school teachers in Korea and other countries utilizing the teacher survey data of the IEA International Computer and Information Literacy Study (ICILS) 2013. The ICILS target population consisted of all students in the eighth grade. We compared Korea with Australia, the Czech Republic, Norway, and Poland, which are nations showing the highest achievements in computer and information literacy. We selected nine questions from the teacher questionnaire and divided them into the categories of computer use, use of ICT for teaching and learning, and the ICT support environment in school. In comparison to their counterparts in other countries, Korean middle school science teachers used computers frequently and also had high ICT self-efficacy. They were confident in their ability to use computers for general tasks, but not in their ability to use computers for teaching and learning. The Korean teachers also had a high percentage of utilization of presentation and graphics software. Also, the proportion of activities concerning the information provided and teacher-led tasks was high, but the proportion of activities for student collaboration or peer interaction was low. In Korea, middle school science teachers had more negative than positive views of using ICT in teaching and learning. The teachers thought that computer-related resource support and digital learning materials were insufficient and that the computer model was outdated in schools. Therefore, we propose to build an ICT infrastructure and to develop and disseminate ICT teaching and learning methods for student activities.

• Korean Journal of Social Welfare
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• v.35
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• pp.1-30
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• 1998

The primary objectives of this research is to identify (1) demographic and behavioral characteristics of donors for social welfare organizations in Korea and (2) factors that predicts the degrees of donors' philanthropic effort measured by the fraction of personal income given to these organizations. This study uses the data based on the responses of 191 participants among 500 donors selected randomly from the donor population of 5 major social welfare organizations. In the demographic aspect, this study showed that donors have higher frequencies in college education, Christianity, married status, age of 30s & 40s, and middle class. In the behavioral aspect, this study showed that donors have higher frequencies in inner motivation for philanthropic participation ("joy of giving"), satisfaction about the activities of social welfare organizations, trust toward funds administration of social welfare organizations, and active participation ("solicitation to others") about donation. This study also showed that donor's duration is distributed around 3 years (median) and donors' donation amount is distributed around 20,000 Won (median). This study found that the median value of donors' philanthropic effort is 1.2 percent and the distribution of philanthropic effort by income has the U shape. Finally, using polynomial regression analysis, this study found that the first power and second power of donor's income, age, continuation motivation of donation, and degree of active participation are statistically significant in predicting the degree of donors' philanthropic effort. This study will contribute to expanding knowledge about donors' characteristics and provide a practical implication for financial resource mobilization strategies in nonprofit nongovernmental sector.

• Journal of Korea Port Economic Association
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• v.32 no.4
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• pp.29-39
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• 2016

As geopolitical, archaeological and strategic interests on cooperation with countries in the Far Eastern Area is gradually increased, countries are competing to attract or install a logistics or manufacturing hub in their countries. In this study, we investigated the relative importance of factors on the main three and nine detailed criteria from the domestic and overseas experts on Far Eastern Area. Using AHP(Analytic Hierarchy Process) analysis, priority importance of factors was derived. As a result, we find that the most important factor was economic factor. In detail, industrial complex creation was the highest factor and the institutional guarantees for the investment on policy and transportation network was second highest factor. Based on analysis result, specific competitiveness level in the 10 region of Far East was follows. Hunchun, Vladivostok, Yanji, Tumen, Rajin, Hassan, Ussuriysk, Cheongjin, Mihaylov Skiing, Nije Jeuchinski were showed in order. Hunchun showed the highest competitive level in location, topography, compliance to the around cities, transportation network, industrial complex, excellence in logistics facilities, long-term investment plans, institutional guarantees for investment, customs efficiency and political stability. However, in other factors such as population and number of households, public facilities, potential demand and resource utilization, Vladivostok showed the highest level.