• Journal of Korea Water Resources Association
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• v.46 no.9
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• pp.947-956
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• 2013

Most of flood protection walls built on the impingement in mountain rivers have been made of concrete. It may cause flood disasters because the smooth wall surface could increase flow velocity. In this study the hydraulic experiments was carried out to evaluate the effect of one side wall with rectangular vertical ribs on flow resistance in open channel. The ratio of the pitch between vertical ribs to its depth, ${\lambda}_{nv}$, was designed so that it include the so-called d type and k type roughness. The range of Froude number, $F_r$, based on hydraulic radius is 0.81~1.12. Flow resistance in the open channel with a rib sidewall depends on the interval length of each ribs and the flow discharge. Maximum flow resistance occurred when ${\lambda}_{nv}$ is 9. In the d type roughness which ${\lambda}_{nv}$ is less than 3, the flow resistance decreases with increase of flow discharge. In the k type roughness which ${\lambda}_{nv}$ is greater than 3, the flow resistance increases with increase of flow discharge. The increments of flow resistance are especially great when ${\lambda}_{nv}$ are 9 and 12. The resistance due to vertical rib is mostly by the shape resistance and the vertical rib on one sidewall of open channel affects on the flow resistance so that the equivalent roughness heights of vertical rib may occur in scale of flow depth. Therefore the vertical ribs may be used to reduce the flow velocity and to move the location of maximum flow velocity from the rib sidewall to the centerward in a cross section of channels.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.3
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• pp.109-119
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• 2016

Purpose : The purpose of this research is to find clinical effects of functional resistance training using weighted vest on gross motor and balance abilities of children with dyskinetic cerebral palsy. Methods : This study selects 3 subjects for 8~12 years old who were diagnosed with children with dyskinetic cerebral palsy. The Design is ABA design of single-subject research design. Baseline(A) and TypeII Baseline(A : 12weeks) phases were received with NDT treatment, Intervention(B : 12weeks) phase provided with 40 minute functional resistance training using weighted vest in a session twice a week. In order to analyze the measure results of gross motor function and performance, balance abilities in children dyskinetic cerebral palsy during baseline, intervention and typeII baseline phase. Result : A statistically significant differences in the total GMFM including walking/running/jumping during baseline, intervention, typeII baseline, but no significant differences in the lying/rolling, sitting, crawling/kneeling and standing. A statistically significant differences in the total GMPM including dissociated movement, coordination, weight shift, stability during baseline, intervention, typeII baseline, but no significant differences in the body alignment domains. A statistically significant differences in the length and surface area ellipse of center of pressure during baseline, intervention, typeII baseline. Conclusion : The intervention method to facilitate multi-joint and closed kinematic chain movement equipped weighted vest applied functional resistance training on children with dyskinetic cerebral palsy effectively improve on gross motor function and performance, balance abilities.

• International Journal of Highway Engineering
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• v.8 no.4 s.30
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• pp.101-113
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• 2006

Generally, asphalt binder modifier increases the viscosity at high temperature as well as at mixing and paving temperature, so that higher temperature is required to produce the hot-mix asphalt. Otherwise, wax is able to improve workability by means of decreasing the viscosity of asphalt binder. In this study, the effect of PE wax used to modify the asphalt binder was evaluated in laboratory. The properties of PE wax modified binder were compared with those of SBS and Crumb Rubber Modified binders. The results showed that wax type I has an effect on strengthening rut resistance as well as improving workability. However, wax type I weaken crack resistance due to making binder harder at intermediate temperature. The results also showed that wax type II has an effect on improving workability and on strengthening crack resistance due to making binder softer.

• Food Science and Preservation
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• v.15 no.5
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• pp.731-735
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• 2008

The coliform group, Salmonella typhimurium and Staphylococcus were analyzed for eliminating of microorganism spore which could be embeded in honey and eradication of studied for heat resistance of thermoacidophilic bacteria was studied for marketing of honey after producing honey drink. The method for analyzing of heat resistance thermoacidophilic bacteria was membrane-seperated cell culture with $0.45\;{\mu}m$ micro-filter and vacuum aspirator. The results of bacteria, coliform group, Salmonella typhimurium and Staphylococcus was negative, but normal method such as sterilization with electrolyzed water, normal micro-filter, high-temperature heating and microwave did not have effect on heat resistance thermoacidophilic bacteria. Also, absolute type micro-filter of $0.45\;{\mu}m$ and $0.8\;{\mu}m$ microfilteration showed higher effect on heat resistance thermoacidophilic bacteria than micro-filter of normal type, showing negative results at all treatments.

• The Plant Pathology Journal
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• v.37 no.6
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• pp.652-661
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• 2021

Xanthomonas citri pv. glycines (Xcg) is a major pathogen of soybean (Glycine max) in South Korea, despite the availability of soybean varieties with some resistance. We conducted a nationwide survey of the incidence and severity of bacterial pustule caused by Xcg. The percentage of infected fields was 7% to 17% between 2015 and 2017. We characterized the diversity of a nationwide collection of 106 Xcg isolates based on avrBs3 banding patterns. The isolates fell into 11 groups, each represented by a type strain; only two of these were similar to isolates collected from 1999 to 2002. The diversity of Xcg strains increased and the dominant strains changed between 1999 and 2017, with three new type strains comprising 44% of the isolates examined in 2012 to 2017. Pathogenicity tests did not show evidence for a shift in the races or aggressiveness of Xcg strains. Korean soybean cultivars, including the widely-grown Daewon cultivar, were susceptible to the 11 new type strains. The cultivar CNS, which carries the rxp resistance gene, was susceptible to most type strains, including two representing 83% of the Korean Xcg strains. In contrast, Williams 82, which also carries rxp, showed resistance to at least five type strains. Collectively, these results suggest that Williams 82 has resistance loci in addition to rxp. The widespread distribution of Xcg, the high virulence of the current endemic strains, and the low resistance of most Korean soybean cultivars collectively favor widespread disease in Korea in years that are favorable to pustule development.

• Journal of Genetic Medicine
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• v.10 no.2
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• pp.81-87
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• 2013

Pseudohypoaldosteronism (PHA), a rare syndrome of systemic or renal mineralocorticoid resistance, is clinically characterized by hyperkalemia, metabolic acidosis, and elevated plasma aldosterone levels with either renal salt wasting or hypertension. PHA is a heterogeneous disorder both clinically and genetically and can be divided into three subgroups; PHA type 1 (PHA1), type 2 (PHA2) and type 3 (PHA3). PHA1 and PHA2 are genetic disorders, and PHA3 is a secondary disease of transient mineralocorticoid resistance mostly associated with urinary tract infections and obstructive uropathies. PHA1 includes two different forms with different severity of the disease and phenotype: a systemic type of disease with autosomal recessive inheritance (caused by mutations of the amiloride-sensitive epithelial sodium channel, ENaC) and a renal form with autosomal dominant inheritance (caused by mutations of the mineralocorticoid receptor, MR). In the kidneys, the distal nephron takes charge of the fine regulation of water absorption and ion handling under the control of aldosterone. Two major intracellular actors necessary for the action of aldosterone are the MR and the ENaC. Impairment of the intracellular aldosterone signal transduction pathway results in resistance to the action of mineralocorticoids, which leads to PHA. Herein, ion handling the distal nephron and the clinico-genetic findings of PHA are reviewed with special emphasis on PHA type 1.

• Genomics & Informatics
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• v.12 no.4
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• pp.276-282
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• 2014

The disease tuberculosis, caused by Mycobacterium tuberculosis (MTB), remains a major cause of morbidity and mortality in developing countries. The evolution of drug-resistant tuberculosis causes a foremost threat to global health. Most drug-resistant MTB clinical strains are showing resistance to isoniazid and rifampicin (RIF), the frontline anti-tuberculosis drugs. Mutation in rpoB, the beta subunit of DNA-directed RNA polymerase of MTB, is reported to be a major cause of RIF resistance. Amongst mutations in the well-defined 81-base-pair central region of the rpoB gene, mutation at codon 450 (S450L) and 445 (H445Y) is mainly associated with RIF resistance. In this study, we modeled two resistant mutants of rpoB (S450L and H445Y) using Modeller9v10 and performed a docking analysis with RIF using AutoDock4.2 and compared the docking results of these mutants with the wild-type rpoB. The docking results revealed that RIF more effectively inhibited the wild-type rpoB with low binding energy than rpoB mutants. The rpoB mutants interacted with RIF with positive binding energy, revealing the incapableness of RIF inhibition and thus showing resistance. Subsequently, this was verified by molecular dynamics simulations. This in silico evidence may help us understand RIF resistance in rpoB mutant strains.

• Safety and Health at Work
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• v.9 no.1
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• pp.17-24
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• 2018

Background: Increasing the slip resistance of floor surfaces would be desirable, but there is a lack of evidence on whether traction properties are linearly correlated with the topographic features of the floor surfaces or what scales of surface roughness are required to effectively control the slipperiness of floors. Objective: This study expands on earlier findings on the effects of floor surface finishes against slip resistance performance and determines the operative ranges of floor surface roughness for optimal slip resistance controls under different risk levels of walking environments. Methods: Dynamic friction tests were conducted among three shoes and nine floor specimens under wet and oily environments and compared with a soapy environment. Results: The test results showed the significant effects of floor surface roughness on slip resistance performance against all the lubricated environments. Compared with the floor-type effect, the shoe-type effect on slip resistance performance was insignificant against the highly polluted environments. The study outcomes also indicated that the oily environment required rougher surface finishes than the wet and soapy ones in their lower boundary ranges of floor surface roughness. Conclusion: The results of this study with previous findings confirm that floor surface finishes require different levels of surface coarseness for different types of environmental conditions to effectively manage slippery walking environments. Collected data on operative ranges of floor surface roughness seem to be a valuable tool to develop practical design information and standards for floor surface finishes to efficiently prevent pedestrian fall incidents.

• Steel and Composite Structures
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• v.38 no.6
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• pp.657-670
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• 2021

This paper presents a designing method for enhancing fire resistance of steel box bridge girders (closed steel box bridge girder supporting a thin concrete slab) through taking into account such parameters namely; fire severity, type of longitudinal stiffeners (I, L, and T shaped), and number of longitudinal stiffeners. A validated 3-D finite element model, developed through the computer program ANSYS, is utilized to go over the fire response of a typical steel box bridge girder using the transient thermo-structural analysis method. Results from the numerical analysis show that fire severity and type of longitudinal stiffeners welded on bottom flange have significant influence on fire resistance of steel box bridge girders. T shaped longitudinal stiffeners applied on bottom flange can highly prevent collapse of steel box bridge girders towards the end of fire exposure. Increase of longitudinal stiffeners on bottom flange and web can slightly enhance fire resistance of steel box bridge girders. Rate of deflection-based criterion can be reliable to evaluate fire resistance of steel box bridge girders in most fire exposure cases. Thus, T shaped longitudinal stiffeners on bottom flange incorporated into bridge fire-resistance design can significantly enhance fire resistance of steel box bridge girders.

• Journal of Advanced Marine Engineering and Technology
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• v.24 no.5
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• pp.58-68
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• 2000

When SS400 steel was welded with low hydrogen type and ilmennite type welding, the effect of post-weld heat treatment(PWHT) was investigated with parameters such as micro vickers hardness, corrosion potential, polarization behaviors, galvanic current, Al anode generating current and Al anode weight loss etc. Hardness of each parts(HAZ, BM, WM) by PWHT in case of low hydrogen type and ilmennite type welding was lower than that of each parts by As-welded However hardness of WM area in case of low hydrogen type and ilmennite type welding was the highest among those three parts regardless of PWHT, Whereas in case of ilmennite type welding, WM area was the highest potential among these three parts on galvanic potential series with As-welded while BM area was the highest potential among these three parts by PWHT on the contrary. And in case of low hydrogen type welding, galvanic corrosion and micro cell corrosion of welding parts was decreased with PWHT. However, It was increased with PWHT in case of ilmennite type welding. Moreover Al anode generating current and anode weight loss in case of low hydrogen type was decreased by PWHT compared to As-wedled but, which was increased than that of As-welded in case of ilmennite type welding. Therefore, it is suggested that Corrosion resistance property in case of low hydrogen type welding is increased by PWHT. However its property was devreased with PWHT in case of ilmennite type welding.