• Title/Summary/Keyword: Residual volume

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New Method for Combined Quantitative Assessment of Air-Trapping and Emphysema on Chest Computed Tomography in Chronic Obstructive Pulmonary Disease: Comparison with Parametric Response Mapping

  • Hye Jeon Hwang;Joon Beom Seo;Sang Min Lee;Namkug Kim;Jaeyoun Yi;Jae Seung Lee;Sei Won Lee;Yeon-Mok Oh;Sang-Do Lee
    • Korean Journal of Radiology
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    • v.22 no.10
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    • pp.1719-1729
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    • 2021
  • Objective: Emphysema and small-airway disease are the two major components of chronic obstructive pulmonary disease (COPD). We propose a novel method of quantitative computed tomography (CT) emphysema air-trapping composite (EAtC) mapping to assess each COPD component. We analyzed the potential use of this method for assessing lung function in patients with COPD. Materials and Methods: A total of 584 patients with COPD underwent inspiration and expiration CTs. Using pairwise analysis of inspiration and expiration CTs with non-rigid registration, EAtC mapping classified lung parenchyma into three areas: Normal, functional air trapping (fAT), and emphysema (Emph). We defined fAT as the area with a density change of less than 60 Hounsfield units (HU) between inspiration and expiration CTs among areas with a density less than -856 HU on inspiration CT. The volume fraction of each area was compared with clinical parameters and pulmonary function tests (PFTs). The results were compared with those of parametric response mapping (PRM) analysis. Results: The relative volumes of the EAtC classes differed according to the Global Initiative for Chronic Obstructive Lung Disease stages (p < 0.001). Each class showed moderate correlations with forced expiratory volume in 1 second (FEV1) and FEV1/forced vital capacity (FVC) (r = -0.659-0.674, p < 0.001). Both fAT and Emph were significant predictors of FEV1 and FEV1/FVC (R2 = 0.352 and 0.488, respectively; p < 0.001). fAT was a significant predictor of mean forced expiratory flow between 25% and 75% and residual volume/total vital capacity (R2 = 0.264 and 0.233, respectively; p < 0.001), while Emph and age were significant predictors of carbon monoxide diffusing capacity (R2 = 0.303; p < 0.001). fAT showed better correlations with PFTs than with small-airway disease on PRM. Conclusion: The proposed quantitative CT EAtC mapping provides comprehensive lung functional information on each disease component of COPD, which may serve as an imaging biomarker of lung function.

Regular Waves-induced Seabed Dynamic Responses around Submerged Breakwater (규칙파동장하 잠제 주변지반의 동적거동에 관한 수치해석)

  • Lee, Kwang-Ho;Ryu, Heung-Won;Kim, Dong-Wook;Kim, Do-Sam;Kim, Tae-Hyung
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.28 no.3
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    • pp.132-145
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    • 2016
  • In case of the seabed around and under gravity structures such as submerged breakwater is exposed to a large wave action long period, the excess pore pressure will be generated significantly due to pore volume change associated with rearrangement soil grains. This effect will lead a seabed liquefaction around and under structures as a result from decrease in the effective stress. Under the seabed liquefaction occurred and developed, the possibility of structure failure will be increased eventually. In this study, to evaluate the liquefaction potential on the seabed quantitatively, numerical analysis was conducted using the expanded 2-dimensional numerical wave tank model and the finite element elasto-plastic model. Under the condition of the regular wave field, the time and spatial series of the deformation of submerged breakwater, the pore water pressure (oscillatory and residual components) and pore water pressure ratio in the seabed were estimated.

Ethanol Fermentation of Fusant between Heterologous Transformant of Saccharomyces cerevisiae and Candida tropicalis in Pilot Scale (Pilot Scale에서의 Fusant의 Ethanol 발효)

  • Seu, Jung-Hwn;Kim, Young-Ho;Lee, Soon-Mo;Bang, Byung-Ho
    • Microbiology and Biotechnology Letters
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    • v.17 no.1
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    • pp.14-18
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    • 1989
  • As the final experiment to assess the possibility of industrial application of FSC14-75, ethanol productivity from liquefied sweet potato starch was examined in a pilot scale of 300 liters. FSC14-75 produced 6.6%(v/v) of ethanol from 13.3% of liquefied sweet potato starch in 8 days, and the residual sugar was 3.15%. The corresponding efficiency was 70% of the theoretical maximum. Since we could isolate unicellular cell and flocculent cell from the fermentation broth, we designated them FSC14-75(S) and FSC14-75(F), respectively. We investigated ethanol productivity of FSC14-75(F) compared with that of FSC14-75(S) from liquefied potato starch in a mini·tar tormentor scale of 2.5 liters. FSC14-75(F) was found more favorable than the counterpart in terms of ethanol productivity, and produced 8.1%(v/v) of ethanol from 15% of liquefied potato starch with an efficiency of 75%. In a pilot scale fermentation with 15% of liquefied sweet potato starch, ethanol productivity of FSC14-75(F) reached maximum level of 7.7%(v/v) after 8 days, and the residual sugar was 1.9%. However, the ethanol productivity was not enhanced by a supplementary addition of Thermamyl to the fermentation broth after sterilization.

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Implant placement simultaneously sinus augmentation using crestal approach in severely atrophic maxilla; minimally invasive approach (골 흡수가 심한 상악 구치부에서 치조정 접근법을 이용하여 상악동 골이식술 동시 임플란트 식립)

  • Kim, Hyun-Joo;Kwon, Eun-Young;Choi, Jeomil;Lee, Ju-Youn;Joo, Ji-Young
    • Journal of Dental Rehabilitation and Applied Science
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    • v.33 no.1
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    • pp.47-54
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    • 2017
  • The atrophy of edentulous ridge and pneumatization of the maxillary sinus often limit the volume of bone available for implant placement on maxillary posterior teeth. Most clinicians suffer difficulties from poor bone quality and quantity on maxillary posterior site. Thus, the success of maxillary posterior implant surgery depends on the increase of the available bone and obtaining a good initial stability of the implant after maxillary sinus reconstruction. The maxillary sinus augmentation methods include a crestal approach and a lateral approach. Less morbidity and complications after operation is major advantage to sinus augmentation using crestal approach than lateral approach. However, when the residual ridge height is ${\geq}6mm$, it is known that crestal approach is appropriate. Also delayed implantation after sinus augmentation is recommended in severely atrophic ridge. We present the three cases of implant placement simultaneously sinus augmentation using crestal approach in posterior maxilla site with ${\leq}3mm$ of residual alveolar bone.

Soil-Water Characteristic Curve of Sandy Soils Containing Biopolymer Solution (바이오폴리머를 포함한 모래지반의 흙-습윤 특성곡선 연구)

  • Jung, Jongwon
    • Journal of the Korean GEO-environmental Society
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    • v.19 no.10
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    • pp.21-26
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    • 2018
  • Soil-water characteristic curve, which is called soil retention curve, is required to explore water flows in unsaturated soils, relative permeability of water in multi-phase fluids flow, and change to stiffness and volume of soils. Thus, the understanding of soil-water characteristic curves of soils help us explore the behavior of soils inclduing fluids. Biopolymers are environmental-friendly materials, which can be completely degraded by microbes and have been believed not to affect the nature. Thus, various biopolymers such as deacetylated power, polyethylene oxide, xanthan gum, alginic acid sodium salt, and polyacrylic acid have been studies for the application to soil remediation, soil improvement, and enhanced oil recovery. PAA (polyacrylic acid) is one of biopolymers, which have shown a great effect in enhanced oil recovery as well as soil remediation because of the improvement of water-flood performance by mobility control. The study on soil-water characteristic curves of sandy soils containing PAA (polyacrylic acid) has been conducted through experimentations and theoretical models. The results show that both capillary entry pressure and residual water saturation dramatically increase according to the increased concentration of PAA (polyacrylic acid). Also, soil-water characteristic curves by theoretical models are quite well consistent with the results by experimental studies. Thus, soil-water characteristic curves of sandy soils containing biopolymers such as PAA (polyacrylic acid) can be estimated using fitting parameters for the theoretical model.

Effets of Steel Fiber Contents on Flexural Creep Behavior of High-Strength Concrete (강섬유 혼입률에 따른 고강도 콘크리트의 휨 크리프 특성)

  • Lim, Seong-Hoon;Kim, Dong-Hwi;Yun, Hyun-Do
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.24 no.2
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    • pp.111-118
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    • 2020
  • In this paper, the flexural creep behavior of hooked-end steel fiber reinforced high-strength concrete was evaluated to investigate the steel fiber content influence on long-term behavior of flexural members. An experimental program consisted of nine prismatic beam specimens with dimensions of 150 × 150 × 600mm reinforced with different contents of steel fiber (0, 0.75 and 1.5% at the volume fraction). To introduce flexural creep loading to notched prismatic beam specimens, a four-point bending test setup was used. The sustained load with 40% of the flexural strength was applied by means of a lever system and controlled by a load cell for 90 days. During sustained loading, crack mouth opening displacement (CMOD) was monitored. Conventional flexural test after creep tests were carried out to evaluate the residual capacity of each specimen. Test results showed that steel fiber content has a significant effect on the flexural creep behavior of high-strength concrete and long-term flexural load with 40% of flexural strength doesn't generate negative effects on the residual capacity of steel fiber reinforced high-strength concrete.

Changes on rice qualify during long-term storaged (미곡의 장기저장에 의한 품질 특성 변화)

  • Lee, B.Y.;Kim, Y.B.;Son, J.R.;Yoon, I.H.;Han, P.J.
    • Applied Biological Chemistry
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    • v.34 no.3
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    • pp.262-264
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    • 1991
  • In order to establish the optimum storage period of rice, storability of rice for 1, 2. 3 and 4 years was investigated. Fat acidity of stored rice for 1, 2, 3 and 4 years was measured to 12.4, 23.6, 30.8 and 41.1 KOHmg/100g, respectively. Reducing sugar of those was analized to 0.31, 0.41, 0.57 and 0.68%. Germination of the stored rice for 1, 2 and 3 years was 97, 93 and 85%, respectively, but that of stored for four years was very low 32%. The longer storage period the higher, the lower water uptake ratio and expanded volume and much the lower total solid in residual liquid and intensity of starch iodine blue value of residual liquid, and the worse panel scores in color, stickness, taste and smell.

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Irregular Waves-Induced Seabed Dynamic Responses around Submerged Breakwater (불규칙파동장하 잠제 주변지반의 동적거동에 관한 수치해석)

  • Lee, Kwang-Ho;Ryu, Heung-Won;Kim, Dong-Wook;Kim, Do-Sam;Kim, Tae-Hyung
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.28 no.4
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    • pp.177-190
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    • 2016
  • In case of the seabed around and under gravity structures such as submerged breakwater is exposed to a large wave action long period, the excess pore pressure will be generated significantly due to pore volume change associated with rearrangement soil grains. This effect will lead a seabed liquefaction around and under structures as a result from decrease in the effective stress. Under the seabed liquefaction occurred and developed, the possibility of structure failure will be increased eventually. Lee et al.(2016) studied for regular waves, and this study considered for irregular waves with the same numerical analysis method used for regular waves. Under the condition of the irregular wave field, the time and spatial series of the deformation of submerged breakwater, the pore water pressure (oscillatory and residual components) and pore water pressure ratio in the seabed were estimated and their results were compared with those of the regular wave field to evaluate the liquefaction potential on the seabed quantitatively. Although present results are based on a limited number of numerical simulations, one of the study's most important findings is that a more safe design can be obtainable when analyzing case with a regular wave condition corresponding to a significant wave of irregular wave.

Compressive and Flexural Properties of Concrete Reinforced with High-strength Hooked-end Steel Fibers (고강도 후크형 강섬유로 보강된 콘크리트의 압축 및 휨 성능)

  • Wang, Qi;Kim, Dong-Hwi;Yun, Hyun-Do;Jang, Seok-Joon;Kim, Sun-Woo
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.25 no.6
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    • pp.209-217
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    • 2021
  • This paper investigates the effect of high strength hooked-end steel fiber content and aspect ratio on the compressive and flexural performance of concrete. A total of ten mixtures were prepared and tested. Concretes with specific compressive strength of 30 MPa were reinforced with three different aspect ratios (l/d) of steel fibers 64, 67, and 80 and three different percentages of steel fibers 0.25, 0.50, and 0.75% by volume of concrete. Tensile strengths of steel fibers with l/d of 64, 67, and 80 are 2,000, 2,400, and 2,100 MPa, respectively. The compressive and flexural properties of plain and steel fiber-reinforced concrete (SFRC) mixtures were evaluated and compared. The experimental results indicated that the incorporation of high-strength hooked-end steel fibers had significant effects on the compressive and flexural performance of concrete. With the increase of steel fiber content, compressive performances, such as Poisson's ratio and toughness, of concrete were improved. The steel fibers with the least l/d of 67 resulted in a larger enhancement of compressive performances. The residual flexural strength, that is, post-cracking flexural resistance and toughness, of concrete is mainly depended on the dosage and aspect ratio of steel fibers. The residual flexural strength at serviceability (SLS) and ultimate limit state (ULS) defined in fib Model Code 2010 (MC2010) is increased as the fiber content and aspect ratio increase.

Mechanical Properties of Polypropylene Fiber mixed in Concrete and Granite Soil Concrete (폴리프로필렌섬유를 혼입한 콘크리트와 화강토콘크리트의 역학적 특성)

  • Jun, Hyung-Soon
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.6
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    • pp.120-126
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    • 2018
  • The study conducted an experiment in which residual aggregate and polypropylene fibers are mixed in concrete, and an experiment in which granite and polypropylene fibers are mixed. Two types of experiments, in particular, changed the amount of polypropylene fibers, and examined the mechanical properties of slump, compressive strength, tensile strength and the like. To establish a light and easy-to-use material for landscape construction and packaging material development by comparing two kinds of experimental results, comparing and analyzing residual aggregate as experimental materials and materials using granite soil to prevent partial destruction due to cracks in drying shrinkage. The more the amount of the PP fibers increases in concrete, the more the volume of the PP fibers increases, the less the slump is determined. As a result of the compressive strength, the cast-down earth concrete is measured to be about 59% to 71% of the concrete strength. As the amount of PP fibers mixed in increased, the compression strength showed a relative decrease. As a result of tensile strength, it is found that the granite concrete is about 68-67% of concrete tensile strength. It was found that the compression strength decreased as the amount of PP fibers mixed in concrete or fire-gant concrete was increased. Then, when polypropylene fibers are mixed in the concrete and the concrete, it is found that tensile strength is increased. By analyzing these results, a fixed amount of PP fiber is mixed in the concrete mixed with the granite soil and utilized for various structures in the field of landscape construction or materials related to packaging, the prevention and improvement effect of the structure is determined.